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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for E2f1

Z-value: 6.52

Motif logo

Transcription factors associated with E2f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027490.11 E2F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f1mm10_v2_chr2_-_154569845_1545698920.952.2e-19Click!

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_79301623 64.65 ENSMUST00000022595.7
regulator of cell cycle
chr2_+_163054682 40.66 ENSMUST00000018005.3
myeloblastosis oncogene-like 2
chr12_-_76709997 36.37 ENSMUST00000166101.1
spectrin beta, erythrocytic
chr11_+_98907801 35.84 ENSMUST00000092706.6
cell division cycle 6
chr17_+_56303396 35.63 ENSMUST00000113038.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_46404224 34.37 ENSMUST00000107764.2
hemogen
chr7_-_142578139 34.24 ENSMUST00000136359.1
H19 fetal liver mRNA
chr7_-_142578093 34.11 ENSMUST00000149974.1
ENSMUST00000152754.1
H19 fetal liver mRNA
chr2_-_28621932 31.72 ENSMUST00000028156.7
ENSMUST00000164290.1
growth factor independent 1B
chr11_-_69948145 31.03 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr4_+_126556935 30.46 ENSMUST00000048391.8
claspin
chr17_+_56303321 30.45 ENSMUST00000001258.8
ubiquitin-like, containing PHD and RING finger domains, 1
chr5_+_45669907 29.93 ENSMUST00000117396.1
non-SMC condensin I complex, subunit G
chr5_+_76840597 29.09 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
RIKEN cDNA C530008M17 gene
chr14_-_47276790 27.23 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
WD repeat and HMG-box DNA binding protein 1
chr16_-_18621366 26.46 ENSMUST00000051160.2
glycoprotein Ib, beta polypeptide
chr13_+_73467197 26.25 ENSMUST00000022099.8
lysophosphatidylcholine acyltransferase 1
chr4_+_126556994 24.70 ENSMUST00000147675.1
claspin
chrX_-_52613936 24.25 ENSMUST00000114857.1
glypican 3
chr6_+_134929118 23.90 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chrX_-_52613913 23.57 ENSMUST00000069360.7
glypican 3
chr12_+_69168808 22.98 ENSMUST00000110621.1
leucine rich repeat protein 1
chr6_+_134929089 22.75 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5
chr8_-_71723308 22.69 ENSMUST00000125092.1
FCH domain only 1
chr7_+_102441685 22.60 ENSMUST00000033283.9
ribonucleotide reductase M1
chrX_-_104671048 22.06 ENSMUST00000042070.5
zinc finger, DHHC domain containing 15
chr11_+_24080664 22.04 ENSMUST00000118955.1
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_108579445 22.01 ENSMUST00000102744.3
origin recognition complex, subunit 1
chrX_-_51205990 21.90 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr9_+_65890237 21.71 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr12_+_24708241 21.49 ENSMUST00000020980.5
ribonucleotide reductase M2
chr7_+_13278778 21.41 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
ligase I, DNA, ATP-dependent
chr11_+_95010277 21.32 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr7_+_67952817 20.64 ENSMUST00000005671.8
insulin-like growth factor I receptor
chr12_+_116405397 20.30 ENSMUST00000084828.3
non-SMC condensin II complex, subunit G2
chr1_-_191575534 20.11 ENSMUST00000027933.5
denticleless homolog (Drosophila)
chr13_-_100775844 19.75 ENSMUST00000075550.3
centromere protein H
chr16_-_15637277 19.72 ENSMUST00000023353.3
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chrX_-_111463149 19.51 ENSMUST00000096348.3
ENSMUST00000113428.2
ribosomal protein S6 kinase polypeptide 6
chr11_+_53519920 19.32 ENSMUST00000147912.1
septin 8
chr13_-_47105790 19.30 ENSMUST00000129352.1
DEK oncogene (DNA binding)
chr5_+_76657673 19.25 ENSMUST00000128112.1
RIKEN cDNA C530008M17 gene
chr5_+_106964319 19.24 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
cell division cycle 7 (S. cerevisiae)
chr1_-_20820213 18.66 ENSMUST00000053266.9
minichromosome maintenance deficient 3 (S. cerevisiae)
chr17_-_56830916 18.57 ENSMUST00000002444.7
ENSMUST00000086801.5
regulatory factor X, 2 (influences HLA class II expression)
chrX_-_136215443 18.46 ENSMUST00000113120.1
ENSMUST00000113118.1
ENSMUST00000058125.8
brain expressed gene 1
chr7_-_141443989 18.25 ENSMUST00000026580.5
leucine-rich and death domain containing
chr1_-_190978954 18.25 ENSMUST00000047409.6
vasohibin 2
chr5_-_138170992 18.22 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_138171248 17.94 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_+_58948890 17.93 ENSMUST00000078267.3
histone cluster 3, H2ba
chr10_-_19851459 17.86 ENSMUST00000059805.4
solute carrier family 35, member D3
chr9_-_61946768 17.75 ENSMUST00000034815.7
kinesin family member 23
chr5_-_138171216 17.73 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr16_+_93883895 17.62 ENSMUST00000023666.4
ENSMUST00000117099.1
ENSMUST00000142316.1
chromatin assembly factor 1, subunit B (p60)
chr9_+_13246982 17.18 ENSMUST00000110583.2
ENSMUST00000169961.1
coiled-coil domain containing 82
chr17_+_35841668 17.17 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr16_+_37011758 17.13 ENSMUST00000071452.5
ENSMUST00000054034.6
polymerase (DNA directed), theta
chr13_-_47106176 16.91 ENSMUST00000021807.6
ENSMUST00000135278.1
DEK oncogene (DNA binding)
chr4_+_115000174 16.83 ENSMUST00000129957.1
Scl/Tal1 interrupting locus
chrX_+_136138996 16.80 ENSMUST00000116527.1
brain expressed gene 4
chr5_+_123749696 16.69 ENSMUST00000031366.7
kinetochore associated 1
chr11_+_95009852 16.67 ENSMUST00000055947.3
sterile alpha motif domain containing 14
chr4_+_115000156 16.36 ENSMUST00000030490.6
Scl/Tal1 interrupting locus
chr4_+_52439235 16.07 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
structural maintenance of chromosomes 2
chr13_+_54701457 15.97 ENSMUST00000037145.7
cadherin-related family member 2
chr6_+_113531675 15.95 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr6_-_126939524 15.57 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
RAD51 associated protein 1
chr8_+_71406003 14.96 ENSMUST00000119976.1
ENSMUST00000120725.1
ankyrin repeat and LEM domain containing 1
chr15_-_55090422 14.94 ENSMUST00000110231.1
ENSMUST00000023059.6
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr8_+_3665747 14.94 ENSMUST00000014118.2
RIKEN cDNA 1810033B17 gene
chr9_+_70679016 14.93 ENSMUST00000144537.1
a disintegrin and metallopeptidase domain 10
chrX_+_71555918 14.87 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr19_-_9899450 14.84 ENSMUST00000025562.7
inner centromere protein
chr3_-_54915867 14.73 ENSMUST00000070342.3
serine rich and transmembrane domain containing 1
chr5_+_115845229 14.43 ENSMUST00000137952.1
ENSMUST00000148245.1
citron
chr16_-_91688703 14.39 ENSMUST00000138560.1
ENSMUST00000023682.4
ENSMUST00000117159.1
ENSMUST00000114031.1
downstream neighbor of SON
chr11_+_53519871 14.38 ENSMUST00000120878.2
septin 8
chr11_+_62248977 14.02 ENSMUST00000018644.2
adenosine A2b receptor
chr6_-_122801639 13.98 ENSMUST00000165884.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr2_+_131491764 13.84 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr17_+_25016343 13.61 ENSMUST00000024983.5
intraflagellar transport 140
chr2_+_131491958 13.48 ENSMUST00000110181.1
ENSMUST00000110180.1
spermine oxidase
chr11_+_87755567 13.28 ENSMUST00000123700.1
RIKEN cDNA A430104N18 gene
chr3_+_114030532 13.17 ENSMUST00000123619.1
ENSMUST00000092155.5
collagen, type XI, alpha 1
chr15_+_73723131 13.13 ENSMUST00000165541.1
ENSMUST00000167582.1
protein tyrosine phosphatase 4a3
chr10_+_3973086 12.86 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_-_84698769 12.79 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr3_+_40800013 12.71 ENSMUST00000026858.5
ENSMUST00000170825.1
polo-like kinase 4
chr4_-_133968611 12.69 ENSMUST00000102552.1
high mobility group nucleosomal binding domain 2
chr1_-_133801031 12.62 ENSMUST00000143567.1
ATPase, Ca++ transporting, plasma membrane 4
chr12_+_24708984 12.56 ENSMUST00000154588.1
ribonucleotide reductase M2
chrX_-_111463103 12.56 ENSMUST00000137712.2
ribosomal protein S6 kinase polypeptide 6
chr19_-_10203880 12.54 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chr18_+_56707725 12.51 ENSMUST00000025486.8
lamin B1
chr1_+_74506044 12.41 ENSMUST00000087215.5
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr15_-_58135047 12.37 ENSMUST00000038194.3
ATPase family, AAA domain containing 2
chrX_+_170009659 12.34 ENSMUST00000179760.1
predicted gene, 21887
chr16_-_18811615 12.23 ENSMUST00000096990.3
cell division cycle 45
chr17_-_25944932 12.23 ENSMUST00000085027.3
NHL repeat containing 4
chr6_+_4755327 12.19 ENSMUST00000176551.1
paternally expressed 10
chr2_-_160912292 12.04 ENSMUST00000109454.1
ENSMUST00000057169.4
elastin microfibril interfacer 3
chr5_+_33820695 12.02 ENSMUST00000075812.4
ENSMUST00000114397.2
ENSMUST00000155880.1
Wolf-Hirschhorn syndrome candidate 1 (human)
chr8_-_124434323 11.91 ENSMUST00000140012.1
piggyBac transposable element derived 5
chrX_-_139871637 11.86 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr4_-_43046196 11.83 ENSMUST00000036462.5
family with sequence similarity 214, member B
chr7_+_100493337 11.72 ENSMUST00000126534.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr13_-_55329723 11.65 ENSMUST00000021941.7
Max dimerization protein 3
chr10_-_21160925 11.65 ENSMUST00000020158.6
myeloblastosis oncogene
chr8_+_94179089 11.59 ENSMUST00000034215.6
metallothionein 1
chrX_-_51205773 11.59 ENSMUST00000114875.1
muscleblind-like 3 (Drosophila)
chr15_+_80091320 11.56 ENSMUST00000009728.6
ENSMUST00000009727.5
synaptogyrin 1
chrX_+_35888808 11.55 ENSMUST00000033419.6
dedicator of cytokinesis 11
chr3_+_40800054 11.52 ENSMUST00000168287.1
polo-like kinase 4
chr18_-_67641329 11.41 ENSMUST00000097542.2
centrosomal protein 76
chr11_+_53519725 11.32 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr14_-_73325773 11.28 ENSMUST00000022701.6
retinoblastoma 1
chr5_-_67847360 11.27 ENSMUST00000072971.6
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr2_+_52072823 11.26 ENSMUST00000112693.2
ENSMUST00000069794.5
Rap1 interacting factor 1 homolog (yeast)
chr19_+_47178820 11.24 ENSMUST00000111808.3
neuralized homolog 1A (Drosophila)
chr4_-_133967893 11.17 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr4_-_152477433 11.17 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_+_45554893 11.16 ENSMUST00000107752.3
hydroxysteroid (17-beta) dehydrogenase 14
chr4_+_24496434 10.94 ENSMUST00000108222.2
ENSMUST00000138567.2
ENSMUST00000050446.6
MMS22-like, DNA repair protein
chr9_-_58741543 10.93 ENSMUST00000098674.4
RIKEN cDNA 2410076I21 gene
chr12_+_109743787 10.91 ENSMUST00000183068.1
miRNA containing gene
chr9_-_21291124 10.88 ENSMUST00000086374.6
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr11_-_11808923 10.84 ENSMUST00000109664.1
ENSMUST00000150714.1
ENSMUST00000047689.4
ENSMUST00000171938.1
ENSMUST00000171080.1
fidgetin-like 1
chr18_-_58209926 10.81 ENSMUST00000025497.6
fibrillin 2
chr10_+_128232065 10.72 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
timeless circadian clock 1
chrX_-_8145679 10.59 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
RNA binding motif protein 3
chr17_-_29888570 10.48 ENSMUST00000171691.1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr7_-_67803489 10.44 ENSMUST00000181235.1
RIKEN cDNA 4833412C05 gene
chr11_+_80089385 10.44 ENSMUST00000108239.1
ENSMUST00000017694.5
ATPase family, AAA domain containing 5
chr7_+_99535439 10.38 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr10_-_91082704 10.38 ENSMUST00000162618.1
ENSMUST00000020157.6
ENSMUST00000160788.1
apoptotic peptidase activating factor 1
chr14_+_32321987 10.30 ENSMUST00000022480.7
oxoglutarate dehydrogenase-like
chr10_-_120476469 10.29 ENSMUST00000072777.7
ENSMUST00000159699.1
high mobility group AT-hook 2
chr17_+_28769307 10.26 ENSMUST00000004986.6
mitogen-activated protein kinase 13
chr4_+_135152496 10.26 ENSMUST00000119564.1
runt related transcription factor 3
chr8_-_122551316 10.20 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr16_+_17646564 10.18 ENSMUST00000182117.1
ENSMUST00000182671.1
ENSMUST00000182344.1
coiled-coil domain containing 74A
chr2_+_29869484 10.09 ENSMUST00000047521.6
ENSMUST00000134152.1
cerebral endothelial cell adhesion molecule
chr18_-_80363622 10.02 ENSMUST00000184366.1
potassium voltage-gated channel, subfamily G, member 2
chr13_+_21722057 10.02 ENSMUST00000110476.3
histone cluster 1, H2bm
chr8_+_75109528 9.97 ENSMUST00000164309.1
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr17_+_35841491 9.95 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr13_-_107022027 9.85 ENSMUST00000117539.1
ENSMUST00000122233.1
ENSMUST00000022204.9
ENSMUST00000159772.1
kinesin family member 2A
chr17_+_25016068 9.84 ENSMUST00000137386.1
intraflagellar transport 140
chr5_-_44101668 9.82 ENSMUST00000087441.4
ENSMUST00000074113.6
prominin 1
chr1_-_190979280 9.76 ENSMUST00000166139.1
vasohibin 2
chr17_-_71526819 9.73 ENSMUST00000024851.9
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr2_-_66124994 9.71 ENSMUST00000028378.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
chr7_+_97453204 9.69 ENSMUST00000050732.7
ENSMUST00000121987.1
potassium channel tetramerisation domain containing 14
chr14_+_99298652 9.67 ENSMUST00000005279.6
Kruppel-like factor 5
chr8_-_78508876 9.65 ENSMUST00000049245.7
RNA binding motif protein, X linked-like-1
chr16_+_17646464 9.60 ENSMUST00000056962.4
coiled-coil domain containing 74A
chr4_+_131873608 9.57 ENSMUST00000053819.3
serine/arginine-rich splicing factor 4
chr2_+_119618717 9.51 ENSMUST00000028771.7
nucleolar and spindle associated protein 1
chr17_+_56304313 9.43 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr8_-_53638945 9.39 ENSMUST00000047768.4
nei like 3 (E. coli)
chr3_+_65666223 9.38 ENSMUST00000099075.2
ENSMUST00000107848.1
ENSMUST00000161794.1
leucine, glutamate and lysine rich 1
chrX_-_47892502 9.33 ENSMUST00000077569.4
ENSMUST00000101616.2
ENSMUST00000088973.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr12_-_109068173 9.29 ENSMUST00000073156.7
brain-enriched guanylate kinase-associated
chr4_+_13743424 9.28 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_154613297 9.28 ENSMUST00000081926.6
ENSMUST00000109702.1
zinc finger protein 341
chr5_-_67847400 9.26 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr4_-_133967235 9.24 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr10_-_80433615 9.21 ENSMUST00000105346.3
ENSMUST00000020377.6
ENSMUST00000105340.1
ENSMUST00000020379.6
ENSMUST00000105344.1
ENSMUST00000105342.1
ENSMUST00000105345.3
ENSMUST00000105343.1
transcription factor 3
chr4_-_116123618 9.21 ENSMUST00000102704.3
ENSMUST00000102705.3
RAD54 like (S. cerevisiae)
chr10_+_128015157 9.17 ENSMUST00000178041.1
ENSMUST00000026461.7
DNA primase, p49 subunit
chr4_-_117929466 9.17 ENSMUST00000097913.2
artemin
chr7_-_83884289 9.07 ENSMUST00000094216.3
mesoderm development candidate 1
chr10_-_81524225 9.02 ENSMUST00000043709.7
guanine nucleotide binding protein, alpha 15
chr14_-_67715585 9.02 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
cell division cycle associated 2
chr7_+_45215753 9.00 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
TEA domain family member 2
chr10_+_100015817 8.95 ENSMUST00000130190.1
ENSMUST00000020129.7
kit ligand
chr13_+_91461050 8.94 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr13_-_51793650 8.90 ENSMUST00000110040.2
ENSMUST00000021900.7
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr9_-_36726374 8.90 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
checkpoint kinase 1
chr3_+_68869563 8.87 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr4_+_11191726 8.85 ENSMUST00000029866.9
ENSMUST00000108324.3
cyclin E2
chr7_-_38107490 8.84 ENSMUST00000108023.3
cyclin E1
chr14_+_31134853 8.80 ENSMUST00000090212.4
5'-nucleotidase domain containing 2
chr10_-_128704978 8.80 ENSMUST00000026416.7
ENSMUST00000026415.7
cyclin-dependent kinase 2
chr6_-_87590701 8.78 ENSMUST00000050887.7
prokineticin receptor 1
chr2_-_151009364 8.77 ENSMUST00000109896.1
ninein-like
chr11_-_34833631 8.72 ENSMUST00000093191.2
spindle apparatus coiled-coil protein 1
chrX_+_37048807 8.71 ENSMUST00000060057.1
sosondowah ankyrin repeat domain family member D
chr18_-_52529692 8.70 ENSMUST00000025409.7
lysyl oxidase
chr3_+_28781305 8.65 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr12_+_117843489 8.65 ENSMUST00000021592.9
cell division cycle associated 7 like
chr8_+_120488416 8.63 ENSMUST00000034279.9
genetic suppressor element 1
chr1_+_191063001 8.61 ENSMUST00000076952.5
ENSMUST00000139340.1
ENSMUST00000078259.6
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr9_-_44344159 8.61 ENSMUST00000077353.7
hydroxymethylbilane synthase
chr13_-_23551648 8.60 ENSMUST00000102971.1
histone cluster 1, H4f
chr19_-_5894100 8.56 ENSMUST00000055911.4
tigger transposable element derived 3
chr16_-_23127702 8.48 ENSMUST00000115338.1
ENSMUST00000115337.1
ENSMUST00000023598.8
replication factor C (activator 1) 4
chr17_-_35516780 8.38 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chrY_+_90784738 8.37 ENSMUST00000179483.1
erythroid differentiation regulator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
21.5 64.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
9.2 92.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
8.7 43.3 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
8.0 31.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
6.8 27.2 GO:0070829 heterochromatin maintenance(GO:0070829)
6.8 47.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
6.3 37.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
6.0 17.9 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
5.9 17.8 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
5.7 85.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
5.6 16.9 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
5.5 22.0 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
5.5 38.5 GO:0098535 de novo centriole assembly(GO:0098535)
5.5 27.3 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
5.4 70.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
5.2 15.7 GO:1904980 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
5.0 55.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
5.0 20.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
4.9 24.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
4.9 34.0 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
4.8 38.6 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
4.8 14.3 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
4.5 22.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
4.5 13.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
4.4 22.2 GO:0042117 monocyte activation(GO:0042117)
4.4 22.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
4.3 98.3 GO:0006270 DNA replication initiation(GO:0006270)
4.2 12.6 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
4.2 12.5 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
3.9 27.3 GO:0046208 spermine catabolic process(GO:0046208)
3.8 34.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.7 14.6 GO:0090095 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
3.6 3.6 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
3.6 10.8 GO:0071694 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
3.6 10.7 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
3.6 10.7 GO:0051311 meiotic metaphase plate congression(GO:0051311)
3.6 64.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.5 53.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
3.3 6.6 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
3.3 9.8 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
3.2 19.5 GO:0042891 antibiotic transport(GO:0042891)
3.2 16.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
3.2 16.0 GO:1904970 brush border assembly(GO:1904970)
3.1 18.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
3.0 12.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
2.9 49.7 GO:0046599 regulation of centriole replication(GO:0046599)
2.9 14.4 GO:0035989 tendon development(GO:0035989)
2.8 14.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
2.7 40.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
2.6 2.6 GO:0051542 elastin biosynthetic process(GO:0051542)
2.6 5.2 GO:0015675 nickel cation transport(GO:0015675)
2.6 20.5 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
2.6 69.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
2.6 7.7 GO:0072278 metanephric comma-shaped body morphogenesis(GO:0072278) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
2.6 10.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.4 7.2 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
2.3 14.0 GO:0031284 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of guanylate cyclase activity(GO:0031284)
2.3 2.3 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
2.3 20.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
2.2 6.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
2.2 4.4 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
2.2 4.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
2.1 12.9 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
2.1 6.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
2.1 46.8 GO:0030261 chromosome condensation(GO:0030261)
2.1 12.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.1 6.3 GO:0045004 DNA replication proofreading(GO:0045004)
2.1 8.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
2.0 2.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
2.0 8.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.0 10.0 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.9 7.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.9 3.8 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
1.9 5.7 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.9 17.0 GO:0048251 elastic fiber assembly(GO:0048251)
1.9 5.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.9 5.6 GO:0061743 motor learning(GO:0061743)
1.9 37.1 GO:0031297 replication fork processing(GO:0031297)
1.8 1.8 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
1.8 5.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
1.8 5.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.8 8.9 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
1.8 56.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.7 10.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
1.7 27.4 GO:1990403 embryonic brain development(GO:1990403)
1.7 3.4 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
1.7 11.6 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.6 4.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
1.6 3.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
1.6 4.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.6 16.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.6 9.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.6 6.4 GO:0032053 ciliary basal body organization(GO:0032053)
1.6 4.8 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.6 6.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.6 15.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.6 6.2 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.5 47.8 GO:0040034 regulation of development, heterochronic(GO:0040034)
1.5 6.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.5 15.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.5 24.4 GO:0033260 nuclear DNA replication(GO:0033260)
1.5 18.3 GO:0019985 translesion synthesis(GO:0019985)
1.5 9.0 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
1.5 7.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.5 7.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
1.5 9.0 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.5 4.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
1.5 7.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
1.5 1.5 GO:0010159 specification of organ position(GO:0010159)
1.4 5.8 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.4 5.7 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
1.4 17.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
1.4 1.4 GO:0000022 mitotic spindle elongation(GO:0000022)
1.4 7.0 GO:0009414 response to water deprivation(GO:0009414)
1.4 4.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
1.4 6.9 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
1.4 12.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.4 10.9 GO:0048102 autophagic cell death(GO:0048102)
1.4 4.1 GO:0006597 spermine biosynthetic process(GO:0006597)
1.3 10.3 GO:0002326 B cell lineage commitment(GO:0002326)
1.3 8.9 GO:0016584 nucleosome positioning(GO:0016584)
1.3 11.4 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
1.3 6.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
1.3 5.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3 5.0 GO:0060032 notochord regression(GO:0060032)
1.3 7.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.2 5.0 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
1.2 9.8 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
1.2 22.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
1.2 17.8 GO:0051382 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
1.2 8.2 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
1.2 4.7 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.2 33.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.2 11.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.1 2.3 GO:0060061 Spemann organizer formation(GO:0060061)
1.1 6.8 GO:0006543 glutamine catabolic process(GO:0006543)
1.1 20.3 GO:0001675 acrosome assembly(GO:0001675)
1.1 4.5 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.1 4.4 GO:0021586 pons maturation(GO:0021586)
1.1 3.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
1.1 6.6 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.1 6.6 GO:0001866 NK T cell proliferation(GO:0001866)
1.1 13.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.1 12.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.1 53.4 GO:0090307 mitotic spindle assembly(GO:0090307)
1.1 6.4 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
1.1 4.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.1 10.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.1 6.3 GO:0006116 NADH oxidation(GO:0006116)
1.1 6.3 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.1 1.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
1.0 11.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.0 9.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
1.0 8.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.0 2.0 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209)
1.0 43.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
1.0 7.8 GO:1904177 regulation of adipose tissue development(GO:1904177)
1.0 5.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.0 2.9 GO:0060435 bronchiole development(GO:0060435)
1.0 9.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
1.0 5.8 GO:0007000 nucleolus organization(GO:0007000)
1.0 28.0 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
1.0 2.9 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
1.0 2.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.0 2.9 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.9 1.9 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.9 3.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.9 8.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.9 26.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.9 28.0 GO:0045026 plasma membrane fusion(GO:0045026)
0.9 6.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.9 5.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.9 10.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.9 6.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.9 2.7 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.9 3.6 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.9 1.8 GO:0032202 telomere assembly(GO:0032202)
0.9 2.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.9 2.6 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.9 1.7 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.9 11.2 GO:0070995 NADPH oxidation(GO:0070995)
0.9 10.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.8 5.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8 1.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.8 6.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.8 2.4 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.8 11.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 21.1 GO:0051310 metaphase plate congression(GO:0051310)
0.8 20.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.8 10.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.8 5.4 GO:0050713 negative regulation of translation in response to stress(GO:0032055) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.8 7.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.8 24.2 GO:0051225 spindle assembly(GO:0051225)
0.8 3.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.7 7.4 GO:0051026 chiasma assembly(GO:0051026)
0.7 14.6 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.7 6.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.7 2.9 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.7 2.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.7 2.9 GO:0034508 centromere complex assembly(GO:0034508)
0.7 5.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 8.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 2.8 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.7 16.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.7 4.9 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.7 2.8 GO:0019042 viral latency(GO:0019042)
0.7 11.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7 2.0 GO:0021764 amygdala development(GO:0021764)
0.7 2.0 GO:0060137 maternal process involved in parturition(GO:0060137)
0.7 6.7 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.7 6.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.7 12.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.7 9.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.6 6.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.6 2.5 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.6 4.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.6 4.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.6 1.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.6 1.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.6 4.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.6 3.0 GO:0035617 stress granule disassembly(GO:0035617)
0.6 3.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 1.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.6 12.6 GO:0030903 notochord development(GO:0030903)
0.6 3.0 GO:0015889 cobalamin transport(GO:0015889)
0.6 4.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.6 8.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.5 1.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.5 6.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.5 5.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.5 4.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 0.5 GO:0072284 metanephric S-shaped body morphogenesis(GO:0072284) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.5 2.5 GO:0072697 protein localization to cell cortex(GO:0072697)
0.5 12.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.5 2.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.5 6.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 28.7 GO:0006334 nucleosome assembly(GO:0006334)
0.5 3.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056) protein localization to nucleolus(GO:1902570)
0.5 3.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.5 3.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.5 10.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.5 5.5 GO:0061072 iris morphogenesis(GO:0061072)
0.5 20.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.5 2.3 GO:0061141 lung ciliated cell differentiation(GO:0061141)
0.5 7.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.4 15.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.4 28.2 GO:0006342 chromatin silencing(GO:0006342)
0.4 0.9 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.4 6.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.4 1.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 2.1 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 9.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4 13.3 GO:0006284 base-excision repair(GO:0006284)
0.4 1.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.4 0.8 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.4 3.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.4 4.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4 5.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4 2.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 1.6 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.4 0.8 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.4 8.6 GO:0007413 axonal fasciculation(GO:0007413)
0.4 2.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 5.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 3.4 GO:0007343 egg activation(GO:0007343)
0.4 5.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 1.5 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.4 1.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.4 1.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 5.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 4.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 10.1 GO:0006706 steroid catabolic process(GO:0006706)
0.3 1.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.3 1.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 1.0 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.3 1.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 1.6 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.3 2.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 15.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3 1.0 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.3 12.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 2.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 2.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 2.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.3 4.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.3 0.9 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 1.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 9.0 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.3 1.7 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.3 15.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 1.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.3 0.8 GO:0061090 positive regulation of sequestering of zinc ion(GO:0061090)
0.3 1.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.3 8.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 3.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 2.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 3.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.3 10.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 2.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 0.3 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.3 1.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 0.8 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 2.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 1.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 12.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 1.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 5.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 2.5 GO:0036010 protein localization to endosome(GO:0036010)
0.2 1.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 4.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 1.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 1.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 2.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.2 0.4 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 1.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 1.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 4.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 9.8 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 2.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 3.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 1.3 GO:0033227 positive regulation of synaptic transmission, dopaminergic(GO:0032226) dsRNA transport(GO:0033227)
0.2 0.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 1.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 7.7 GO:0009409 response to cold(GO:0009409)
0.2 1.0 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 0.6 GO:0061428 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2 1.0 GO:0097503 sialylation(GO:0097503)
0.2 5.9 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.2 1.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 3.2 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 1.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 2.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 1.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 0.8 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 0.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 8.1 GO:0060976 coronary vasculature development(GO:0060976)
0.2 1.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 1.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 3.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.2 3.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 2.9 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.2 1.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 5.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 0.5 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.2 1.9 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2 1.3 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.8 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.2 1.5 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.2 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 5.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 1.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.1 GO:0035563 regulation of chromatin binding(GO:0035561) positive regulation of chromatin binding(GO:0035563)
0.2 1.4 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2 3.2 GO:0032098 regulation of appetite(GO:0032098)
0.2 1.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.5 GO:0060060 positive regulation of axon extension involved in axon guidance(GO:0048842) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 1.9 GO:0097264 self proteolysis(GO:0097264)
0.1 9.5 GO:0051028 mRNA transport(GO:0051028)
0.1 3.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.7 GO:0031053 primary miRNA processing(GO:0031053)
0.1 2.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 5.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.4 GO:0006817 phosphate ion transport(GO:0006817)
0.1 8.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 4.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 3.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 7.6 GO:0048477 oogenesis(GO:0048477)
0.1 0.2 GO:0072708 response to sorbitol(GO:0072708)
0.1 4.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.3 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 7.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 2.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.4 GO:0010286 heat acclimation(GO:0010286)
0.1 1.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.9 GO:0030539 male genitalia development(GO:0030539)
0.1 3.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.5 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.7 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 7.4 GO:0000910 cytokinesis(GO:0000910)
0.1 1.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 1.3 GO:0006907 pinocytosis(GO:0006907)
0.1 0.9 GO:0070203 regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
0.1 3.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 2.1 GO:0048854 brain morphogenesis(GO:0048854)
0.1 4.3 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.1 0.5 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.1 1.5 GO:0003416 endochondral bone growth(GO:0003416)
0.1 0.2 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.1 11.1 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 2.2 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 1.7 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 3.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.7 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.7 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.2 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.9 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 56.7 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
9.1 45.5 GO:0031523 Myb complex(GO:0031523)
9.0 134.7 GO:0042555 MCM complex(GO:0042555)
8.6 25.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
8.5 25.4 GO:0033186 CAF-1 complex(GO:0033186)
6.9 69.1 GO:0000796 condensin complex(GO:0000796)
6.2 37.2 GO:0098536 deuterosome(GO:0098536)
5.9 17.8 GO:1990423 RZZ complex(GO:1990423)
4.8 33.8 GO:0008091 spectrin(GO:0008091)
4.7 19.0 GO:0090537 CERF complex(GO:0090537)
4.1 12.3 GO:0071920 cleavage body(GO:0071920)
4.1 12.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
4.0 20.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
3.6 14.3 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
3.6 17.8 GO:0097149 centralspindlin complex(GO:0097149)
3.5 21.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
3.4 30.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
3.0 12.1 GO:0000802 transverse filament(GO:0000802)
3.0 9.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
2.8 22.2 GO:0042382 paraspeckles(GO:0042382)
2.6 10.4 GO:0043293 apoptosome(GO:0043293)
2.4 9.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.4 7.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.3 20.8 GO:0030991 intraciliary transport particle A(GO:0030991)
2.3 20.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
2.3 11.3 GO:0035189 Rb-E2F complex(GO:0035189)
2.2 15.4 GO:0005638 lamin filament(GO:0005638)
2.1 144.5 GO:0005657 replication fork(GO:0005657)
2.1 29.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
2.0 8.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.0 22.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.0 14.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
2.0 9.8 GO:0071914 prominosome(GO:0071914)
1.9 5.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.9 7.5 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
1.9 31.6 GO:0032593 insulin-responsive compartment(GO:0032593)
1.8 59.2 GO:0051233 spindle midzone(GO:0051233)
1.8 5.4 GO:1990716 axonemal central apparatus(GO:1990716)
1.8 17.6 GO:0072687 meiotic spindle(GO:0072687)
1.7 6.9 GO:0008623 CHRAC(GO:0008623)
1.7 11.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.7 13.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.6 13.0 GO:0070652 HAUS complex(GO:0070652)
1.6 21.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.6 9.7 GO:0044530 supraspliceosomal complex(GO:0044530)
1.6 16.0 GO:0005652 nuclear lamina(GO:0005652)
1.6 16.0 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.6 4.8 GO:0031417 NatC complex(GO:0031417)
1.5 3.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.5 4.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.4 10.1 GO:0001740 Barr body(GO:0001740)
1.4 14.4 GO:0001739 sex chromatin(GO:0001739)
1.3 2.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.2 6.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
1.2 25.5 GO:0010369 chromocenter(GO:0010369)
1.2 6.0 GO:0070876 SOSS complex(GO:0070876)
1.2 10.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.1 6.9 GO:0070531 BRCA1-A complex(GO:0070531)
1.1 38.8 GO:0000788 nuclear nucleosome(GO:0000788)
1.1 11.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.1 5.6 GO:0044301 climbing fiber(GO:0044301)
1.1 3.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.1 4.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.1 10.8 GO:0045298 tubulin complex(GO:0045298)
1.1 6.4 GO:0031933 telomeric heterochromatin(GO:0031933)
1.0 4.1 GO:0033553 rDNA heterochromatin(GO:0033553)
1.0 21.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.0 5.0 GO:1990037 Lewy body core(GO:1990037)
1.0 12.7 GO:0031616 spindle pole centrosome(GO:0031616)
1.0 13.6 GO:0097539 ciliary transition fiber(GO:0097539)
1.0 53.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.9 68.0 GO:0005844 polysome(GO:0005844)
0.9 5.6 GO:0071547 piP-body(GO:0071547)
0.9 15.7 GO:0044453 nuclear membrane part(GO:0044453)
0.9 10.1 GO:0005687 U4 snRNP(GO:0005687)
0.9 5.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.9 8.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.8 9.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 8.8 GO:0000974 Prp19 complex(GO:0000974)
0.8 6.2 GO:0097433 dense body(GO:0097433)
0.8 4.6 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.8 5.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8 13.6 GO:0031143 pseudopodium(GO:0031143)
0.7 6.6 GO:0061574 ASAP complex(GO:0061574)
0.7 2.1 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.7 12.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.7 25.3 GO:0000786 nucleosome(GO:0000786)
0.7 2.0 GO:0030870 Mre11 complex(GO:0030870)
0.7 4.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.7 6.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.7 65.8 GO:0005814 centriole(GO:0005814)
0.6 19.6 GO:0097228 sperm principal piece(GO:0097228)
0.6 1.8 GO:0030905 retromer, tubulation complex(GO:0030905)
0.6 6.9 GO:0005686 U2 snRNP(GO:0005686)
0.5 4.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 22.9 GO:0015030 Cajal body(GO:0015030)
0.5 8.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 6.9 GO:0036038 MKS complex(GO:0036038)
0.5 8.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5 42.4 GO:0016363 nuclear matrix(GO:0016363)
0.5 1.0 GO:0035976 AP1 complex(GO:0035976)
0.5 9.9 GO:0035869 ciliary transition zone(GO:0035869)
0.5 22.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 5.0 GO:0097542 ciliary tip(GO:0097542)
0.4 13.9 GO:0002080 acrosomal membrane(GO:0002080)
0.4 10.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 25.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.4 1.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 13.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 69.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.4 21.3 GO:0045171 intercellular bridge(GO:0045171)
0.4 2.1 GO:0034709 methylosome(GO:0034709)
0.4 2.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.4 1.7 GO:0033010 paranodal junction(GO:0033010)
0.4 6.9 GO:0031528 microvillus membrane(GO:0031528)
0.4 1.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.4 3.0 GO:0061689 tricellular tight junction(GO:0061689)
0.4 17.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 55.3 GO:0001650 fibrillar center(GO:0001650)
0.3 1.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.3 3.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 3.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 8.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 25.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 4.5 GO:0043083 synaptic cleft(GO:0043083)
0.3 3.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.3 2.2 GO:0090543 Flemming body(GO:0090543)
0.3 3.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 15.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 2.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 11.4 GO:0016592 mediator complex(GO:0016592)
0.3 5.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 4.3 GO:0005685 U1 snRNP(GO:0005685)
0.3 19.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 3.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 2.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 3.0 GO:0035253 ciliary rootlet(GO:0035253)
0.3 7.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 3.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 16.4 GO:0016605 PML body(GO:0016605)
0.3 184.3 GO:0005694 chromosome(GO:0005694)
0.3 1.1 GO:0032021 NELF complex(GO:0032021)
0.3 4.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 1.7 GO:0097165 nuclear stress granule(GO:0097165)
0.3 0.8 GO:0071953 elastic fiber(GO:0071953)
0.3 3.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 2.9 GO:0045179 apical cortex(GO:0045179)
0.3 1.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.7 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 5.5 GO:0005859 muscle myosin complex(GO:0005859)
0.2 7.5 GO:0097440 apical dendrite(GO:0097440)
0.2 34.2 GO:0005681 spliceosomal complex(GO:0005681)
0.2 15.6 GO:0005643 nuclear pore(GO:0005643)
0.2 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 1.6 GO:0031209 SCAR complex(GO:0031209)
0.2 2.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 1.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 29.8 GO:0001726 ruffle(GO:0001726)
0.2 5.0 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.2 1.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.4 GO:0002102 podosome(GO:0002102)
0.1 0.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.4 GO:0034399 nuclear periphery(GO:0034399)
0.1 0.6 GO:1990696 USH2 complex(GO:1990696)
0.1 0.6 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 10.0 GO:0030175 filopodium(GO:0030175)
0.1 2.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 4.4 GO:0016459 myosin complex(GO:0016459)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.9 GO:0071203 WASH complex(GO:0071203)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.1 2.4 GO:0031519 PcG protein complex(GO:0031519)
0.1 7.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 2.7 GO:0030686 90S preribosome(GO:0030686)
0.1 27.7 GO:0043292 contractile fiber(GO:0043292)
0.1 0.8 GO:0045120 pronucleus(GO:0045120)
0.1 2.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 7.1 GO:0005581 collagen trimer(GO:0005581)
0.1 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 6.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 6.1 GO:0005882 intermediate filament(GO:0005882)
0.1 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 5.9 GO:0005811 lipid particle(GO:0005811)
0.1 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 10.1 GO:0043209 myelin sheath(GO:0043209)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 27.8 GO:0005730 nucleolus(GO:0005730)
0.0 3.6 GO:0005604 basement membrane(GO:0005604)
0.0 4.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.7 GO:0030118 clathrin coat(GO:0030118)
0.0 7.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 4.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.7 82.3 GO:0031493 nucleosomal histone binding(GO:0031493)
11.3 56.7 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
10.3 61.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
9.1 27.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
9.1 27.3 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
9.0 45.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
6.3 19.0 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
6.2 18.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
5.7 28.5 GO:0043515 kinetochore binding(GO:0043515)
5.6 16.9 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
4.9 54.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
4.9 4.9 GO:0015616 DNA translocase activity(GO:0015616)
4.3 17.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
4.3 12.8 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
3.9 19.5 GO:0042895 antibiotic transporter activity(GO:0042895)
3.6 7.2 GO:0000405 bubble DNA binding(GO:0000405)
3.6 18.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
3.1 15.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
3.1 12.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
3.1 18.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
3.1 33.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.0 8.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.9 8.7 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
2.8 22.0 GO:0043559 insulin binding(GO:0043559)
2.6 107.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
2.6 12.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.6 15.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
2.5 7.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
2.5 7.5 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
2.5 22.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
2.4 9.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
2.4 14.3 GO:0033592 RNA strand annealing activity(GO:0033592)
2.3 9.4 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
2.3 14.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
2.2 17.5 GO:0070087 chromo shadow domain binding(GO:0070087)
2.0 8.0 GO:0031708 endothelin B receptor binding(GO:0031708)
2.0 6.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
2.0 17.9 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.0 11.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.9 7.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
1.9 5.7 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
1.8 9.2 GO:0036310 annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
1.8 14.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.8 5.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.8 16.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.7 12.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.7 58.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.7 6.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.6 22.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.6 6.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.5 6.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.5 7.5 GO:0030621 U4 snRNA binding(GO:0030621)
1.5 9.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.5 10.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.5 8.8 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
1.4 15.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.4 8.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.4 10.0 GO:0003678 DNA helicase activity(GO:0003678)
1.4 15.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.3 4.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.3 8.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.3 10.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.3 4.0 GO:0031751 D4 dopamine receptor binding(GO:0031751)
1.3 55.5 GO:0070412 R-SMAD binding(GO:0070412)
1.3 5.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.3 3.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.2 4.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.2 4.8 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
1.2 14.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
1.2 4.7 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.2 5.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.2 4.6 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.2 9.2 GO:0070644 vitamin D response element binding(GO:0070644)
1.1 14.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
1.1 7.8 GO:0042289 MHC class II protein binding(GO:0042289)
1.1 6.6 GO:0043237 laminin-1 binding(GO:0043237)
1.1 3.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.1 6.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.0 8.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.0 32.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.0 18.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.0 4.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.9 10.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.9 2.8 GO:0019002 GMP binding(GO:0019002)
0.9 10.3 GO:0003680 AT DNA binding(GO:0003680)
0.9 7.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.9 5.5 GO:0004359 glutaminase activity(GO:0004359)
0.9 2.7 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.9 27.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.9 11.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.8 25.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8 2.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.8 2.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.8 5.7 GO:0045545 syndecan binding(GO:0045545)
0.8 2.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.8 5.3 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.7 4.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.7 5.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.7 2.2 GO:0030519 snoRNP binding(GO:0030519)
0.7 2.9 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.7 5.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7 2.1 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.7 2.1 GO:0009041 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.7 10.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.7 7.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7 14.9 GO:0035173 histone kinase activity(GO:0035173)
0.7 36.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.7 5.4 GO:0050897 cobalt ion binding(GO:0050897)
0.7 34.7 GO:0042169 SH2 domain binding(GO:0042169)
0.7 2.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.7 2.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.7 26.4 GO:0030506 ankyrin binding(GO:0030506)
0.7 3.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.6 5.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 13.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 6.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.6 26.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.6 5.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.6 6.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 6.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.6 3.6 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.6 8.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.6 4.1 GO:0019808 polyamine binding(GO:0019808)
0.6 2.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.6 3.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.6 8.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.6 25.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.6 5.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 4.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.6 2.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 2.2 GO:2001069 glycogen binding(GO:2001069)
0.5 1.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.5 63.1 GO:0004386 helicase activity(GO:0004386)
0.5 5.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.5 8.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 5.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 12.5 GO:0043274 phospholipase binding(GO:0043274)
0.5 2.5 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.5 6.4 GO:0005522 profilin binding(GO:0005522)
0.5 4.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.5 5.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.5 2.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.5 2.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.5 94.1 GO:0042393 histone binding(GO:0042393)
0.5 8.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 25.7 GO:0070888 E-box binding(GO:0070888)
0.5 33.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.5 1.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 11.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.5 4.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 1.8 GO:1990460 leptin receptor binding(GO:1990460)
0.4 4.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.4 8.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 1.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.4 2.1 GO:1990188 euchromatin binding(GO:1990188)
0.4 2.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 8.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.4 1.9 GO:0071253 connexin binding(GO:0071253)
0.4 2.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.4 3.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.4 4.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 4.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.4 0.7 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4 6.5 GO:0004707 MAP kinase activity(GO:0004707)
0.4 10.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 1.7 GO:0038132 neuregulin binding(GO:0038132)
0.3 10.5 GO:0001968 fibronectin binding(GO:0001968)
0.3 2.6 GO:0070990 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.3 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.5 GO:0005113 patched binding(GO:0005113)
0.3 1.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3 31.5 GO:0003777 microtubule motor activity(GO:0003777)
0.3 2.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 13.1 GO:0031491 nucleosome binding(GO:0031491)
0.3 6.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 2.0 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 6.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 4.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 3.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 4.6 GO:0010181 FMN binding(GO:0010181)
0.3 2.4 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091) CTD phosphatase activity(GO:0008420)
0.3 1.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.3 2.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 10.0 GO:0008009 chemokine activity(GO:0008009)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 3.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 7.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 4.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.4 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 1.4 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 14.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 2.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.2 2.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 4.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 2.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 6.1 GO:0070840 dynein complex binding(GO:0070840)
0.2 2.2 GO:0008527 taste receptor activity(GO:0008527)
0.2 2.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 5.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 2.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.2 4.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 10.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 2.5 GO:0048156 tau protein binding(GO:0048156)
0.2 14.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 7.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 3.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 21.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 1.3 GO:0034452 dynactin binding(GO:0034452)
0.2 2.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 4.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 9.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 2.1 GO:0050692 DBD domain binding(GO:0050692)
0.2 7.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 3.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 4.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 6.2 GO:0042805 actinin binding(GO:0042805)
0.2 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 3.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 3.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 4.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 3.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 13.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 6.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.2 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 6.0 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 7.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 7.0 GO:0005507 copper ion binding(GO:0005507)
0.1 7.3 GO:0019894 kinesin binding(GO:0019894)
0.1 3.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.1 2.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 3.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 3.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 4.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 4.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 20.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 10.7 GO:0019902 phosphatase binding(GO:0019902)
0.1 2.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 15.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 3.3 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.1 0.7 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 3.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.3 GO:0042301 phosphate ion binding(GO:0042301)
0.1 3.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 2.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 4.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 7.9 GO:0031072 heat shock protein binding(GO:0031072)
0.1 1.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 25.4 GO:0003682 chromatin binding(GO:0003682)
0.1 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 3.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 39.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 3.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 10.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 10.1 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.7 GO:0003774 motor activity(GO:0003774)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 2.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 9.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 18.0 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 3.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 39.4 GO:0003677 DNA binding(GO:0003677)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 4.4 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 221.3 PID ATR PATHWAY ATR signaling pathway
2.1 102.3 PID AURORA B PATHWAY Aurora B signaling
2.1 203.5 PID E2F PATHWAY E2F transcription factor network
1.1 4.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.0 28.6 PID ATM PATHWAY ATM pathway
1.0 23.1 PID FANCONI PATHWAY Fanconi anemia pathway
1.0 43.7 PID PLK1 PATHWAY PLK1 signaling events
1.0 33.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.8 29.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.7 22.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 3.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.6 8.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.6 8.9 PID BARD1 PATHWAY BARD1 signaling events
0.6 2.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 10.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 5.4 PID MYC PATHWAY C-MYC pathway
0.5 8.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 23.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.5 14.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.5 7.3 PID IL5 PATHWAY IL5-mediated signaling events
0.5 20.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.5 16.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.5 7.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.4 6.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 3.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 36.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 32.8 PID CMYB PATHWAY C-MYB transcription factor network
0.3 12.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 13.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 11.5 PID REELIN PATHWAY Reelin signaling pathway
0.3 9.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.3 7.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 3.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 3.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 2.2 PID TNF PATHWAY TNF receptor signaling pathway
0.3 19.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 14.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 12.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 5.3 PID IL1 PATHWAY IL1-mediated signaling events
0.2 2.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 10.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 4.7 PID ENDOTHELIN PATHWAY Endothelins
0.2 13.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 1.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 5.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 33.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 8.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 5.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 5.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 5.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 3.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 1.4 ST GAQ PATHWAY G alpha q Pathway
0.1 1.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 4.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.8 PID BMP PATHWAY BMP receptor signaling
0.1 1.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 18.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 142.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
5.7 101.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
5.1 66.6 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
4.6 78.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
4.4 8.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
3.5 13.9 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
3.1 43.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
3.0 45.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
3.0 29.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.4 28.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
2.3 11.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.2 13.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.0 22.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.8 26.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.7 29.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.6 86.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.4 38.7 REACTOME KINESINS Genes involved in Kinesins
1.3 36.1 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
1.0 6.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.8 42.6 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.8 39.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.8 9.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.8 15.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.7 32.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 17.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7 58.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.7 18.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.7 4.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6 20.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.6 6.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.5 8.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 26.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 7.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.5 9.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 15.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5 7.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.5 4.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.5 23.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 12.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 4.8 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.4 22.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 2.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 2.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.4 5.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 20.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 11.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 12.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 4.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 8.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 5.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 7.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 10.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 11.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 3.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 13.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 7.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 3.4 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.3 6.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 22.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 1.7 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 15.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.3 6.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.3 7.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.3 5.7 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.3 2.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.3 5.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.3 10.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 4.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 2.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 20.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 3.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.3 4.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.3 1.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 5.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 12.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 3.5 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.2 3.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 8.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 14.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 1.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 5.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 2.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.6 REACTOME RNA POL II TRANSCRIPTION Genes involved in RNA Polymerase II Transcription
0.1 2.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 2.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 3.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 8.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 6.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 3.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 1.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 4.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.2 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 3.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events