avrg: GSE58827: Dynamics of the Mouse Liver


Results for Batf3

Z-value: 0.70

Motif logo

Transcription factors associated with Batf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000026630.4 basic leucine zipper transcription factor, ATF-like 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of Batf3 motif

Sorted Z-values of Batf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_67549173 3.79 ENSMUST00000115050.1
spire homolog 1 (Drosophila)
chr3_+_135212557 2.98 ENSMUST00000062893.7
centromere protein E
chr14_-_87141114 2.17 ENSMUST00000168889.1
diaphanous homolog 3 (Drosophila)
chr2_+_109280738 2.06 ENSMUST00000028527.7
kinesin family member 18A
chr6_-_86669136 1.95 ENSMUST00000001184.7
MAX dimerization protein 1
chr14_-_87141206 1.91 ENSMUST00000022599.7
diaphanous homolog 3 (Drosophila)
chr10_+_120765774 1.79 ENSMUST00000056994.3
RIKEN cDNA 4921513I03 gene
chr3_+_40800054 1.49 ENSMUST00000168287.1
polo-like kinase 4
chr13_-_22042949 1.30 ENSMUST00000091741.4
histone cluster 1, H2ag
chr15_+_79347534 1.28 ENSMUST00000096350.3
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr13_+_22043189 1.15 ENSMUST00000110452.1
histone cluster 1, H2bj
chr11_-_59163281 1.04 ENSMUST00000069631.2
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr14_+_50807915 0.95 ENSMUST00000036126.5
poly (ADP-ribose) polymerase family, member 2
chr4_+_130360132 0.92 ENSMUST00000105994.3
small nuclear ribonucleoprotein 40 (U5)
chr13_+_5861489 0.91 ENSMUST00000000080.6
Kruppel-like factor 6
chr12_+_4082574 0.85 ENSMUST00000020986.7
DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_-_126830632 0.85 ENSMUST00000112583.1
NCK-associated protein 5
chr6_-_124464772 0.78 ENSMUST00000008297.4
calsyntenin 3
chr4_-_107810948 0.75 ENSMUST00000097930.1
RIKEN cDNA B230314M03 gene
chr12_-_69159109 0.75 ENSMUST00000037023.8
ribosomal protein S29
chr6_-_83054415 0.74 ENSMUST00000113962.1
HtrA serine peptidase 2
chr5_+_31698050 0.73 ENSMUST00000114507.3
brain and reproductive organ-expressed protein
chr12_+_4082596 0.72 ENSMUST00000049584.5
DnaJ (Hsp40) homolog, subfamily C, member 27
chr2_-_125123618 0.71 ENSMUST00000142718.1
myelin basic protein expression factor 2, repressor
chr5_+_107497762 0.71 ENSMUST00000152474.1
RIKEN cDNA A830010M20 gene
chr7_+_3703979 0.69 ENSMUST00000006496.8
ribosomal protein S9
chr7_+_3704025 0.67 ENSMUST00000108623.1
ribosomal protein S9
chr7_+_3704307 0.65 ENSMUST00000108624.1
ribosomal protein S9
chr5_+_107497718 0.63 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr11_-_69323768 0.62 ENSMUST00000092973.5
centrobin, centrosomal BRCA2 interacting protein
chr6_+_57703051 0.55 ENSMUST00000151042.1
LanC (bacterial lantibiotic synthetase component C)-like 2
chr5_+_142960343 0.54 ENSMUST00000031565.8
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr18_+_44828471 0.48 ENSMUST00000037763.7
YTH domain containing 2
chr3_-_158036566 0.47 ENSMUST00000137444.1
serine/arginine-rich splicing factor 11
chr3_-_158036630 0.45 ENSMUST00000121326.1
serine/arginine-rich splicing factor 11
chr17_-_56476462 0.41 ENSMUST00000067538.5
protein tyrosine phosphatase, receptor type, S
chr2_+_120609383 0.40 ENSMUST00000124187.1
HAUS augmin-like complex, subunit 2
chr17_+_55892184 0.31 ENSMUST00000054780.8
zinc finger protein 959
chr8_-_60954726 0.31 ENSMUST00000110302.1
chloride channel 3
chr3_+_67374116 0.30 ENSMUST00000061322.8
myeloid leukemia factor 1
chr7_+_90442729 0.30 ENSMUST00000061767.4
CREB/ATF bZIP transcription factor
chr4_-_130359915 0.30 ENSMUST00000134159.2
zinc finger, CCHC domain containing 17
chr16_+_20696175 0.29 ENSMUST00000128273.1
family with sequence similarity 131, member A
chr1_-_126830786 0.29 ENSMUST00000162646.1
NCK-associated protein 5
chr16_+_38562806 0.25 ENSMUST00000171687.1
transmembrane protein 39a
chr11_-_59163696 0.24 ENSMUST00000137433.1
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr16_+_38562821 0.23 ENSMUST00000163948.1
transmembrane protein 39a
chrX_+_74309089 0.22 ENSMUST00000130581.1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr3_+_158036662 0.22 ENSMUST00000072080.3
leucine rich repeat containing 40
chr5_-_137149320 0.21 ENSMUST00000041226.8
mucin 3, intestinal
chr1_+_74791516 0.16 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr9_-_119322421 0.13 ENSMUST00000040853.4
oxidative-stress responsive 1
chr11_-_70237852 0.13 ENSMUST00000108575.2
RIKEN cDNA 0610010K14 gene
chr10_-_17947997 0.07 ENSMUST00000037879.6
headcase homolog (Drosophila)
chr8_+_106011491 0.07 ENSMUST00000034375.4
dihydrouridine synthase 2-like (SMM1, S. cerevisiae)
chr5_+_25222862 0.07 ENSMUST00000045737.7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr17_-_27907706 0.06 ENSMUST00000025057.4
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_-_80324418 0.06 ENSMUST00000047362.4
RCC1 domain containing 1
chr4_+_32238950 0.04 ENSMUST00000037416.6
BTB and CNC homology 2
chrX_-_8175890 0.02 ENSMUST00000143984.1
TBC1 domain family, member 25
chr5_-_130255525 0.02 ENSMUST00000026387.4
Shwachman-Bodian-Diamond syndrome homolog (human)
chr3_-_107696462 0.02 ENSMUST00000029490.8
S-adenosylhomocysteine hydrolase-like 1
chr2_-_120609283 0.01 ENSMUST00000102496.1
leucine rich repeat containing 57
chr17_-_24707617 0.00 ENSMUST00000126319.1
transducin (beta)-like 3
chr11_-_70237638 0.00 ENSMUST00000100950.3
RIKEN cDNA 0610010K14 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.5 1.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.5 2.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.5 3.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 1.5 GO:0046601 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.1 0.6 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.6 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 0.7 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.4 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.1 0.9 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.8 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 2.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 1.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 1.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 1.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 1.5 GO:0098536 deuterosome(GO:0098536)
0.1 0.5 GO:0044393 microspike(GO:0044393)
0.1 3.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0043515 kinetochore binding(GO:0043515)
0.3 2.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.1 2.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production