avrg: GSE58827: Dynamics of the Mouse Liver


Results for Batf

Z-value: 0.80

Motif logo

Transcription factors associated with Batf

Gene Symbol Gene ID Gene Info
ENSMUSG00000034266.5 basic leucine zipper transcription factor, ATF-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of Batf motif

Sorted Z-values of Batf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_142661858 7.99 ENSMUST00000145896.2
insulin-like growth factor 2
chr7_-_142661305 7.75 ENSMUST00000105936.1
insulin-like growth factor 2
chr3_-_123034943 2.96 ENSMUST00000029761.7
myozenin 2
chr14_-_33185489 2.58 ENSMUST00000159606.1
WD repeat and FYVE domain containing 4
chr13_-_21780616 2.50 ENSMUST00000080511.2
histone cluster 1, H1b
chr2_+_164948219 2.15 ENSMUST00000017881.2
matrix metallopeptidase 9
chr7_-_45211877 1.91 ENSMUST00000033057.7
dickkopf-like 1
chr5_-_44099220 1.54 ENSMUST00000165909.1
prominin 1
chr1_-_171649002 1.49 ENSMUST00000111276.3
SLAM family member 7
chr11_-_79059872 1.46 ENSMUST00000141409.1
kinase suppressor of ras 1
chr14_-_33185066 1.32 ENSMUST00000061753.8
WD repeat and FYVE domain containing 4
chr10_+_88091070 1.27 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr2_-_45110241 1.13 ENSMUST00000177302.1
zinc finger E-box binding homeobox 2
chr15_+_103453782 1.05 ENSMUST00000047405.7
NCK associated protein 1 like
chr2_+_13573927 1.03 ENSMUST00000141365.1
chr5_-_149051300 1.03 ENSMUST00000110505.1
high mobility group box 1
chr7_-_126369543 0.96 ENSMUST00000032997.6
linker for activation of T cells
chr5_+_31116702 0.93 ENSMUST00000013771.8
tripartite motif-containing 54
chr7_+_30787897 0.89 ENSMUST00000098559.1
keratinocyte differentiation associated protein
chr3_+_14641722 0.87 ENSMUST00000029071.8
carbonic anhydrase 13
chr18_+_82910863 0.82 ENSMUST00000171238.1
zinc finger protein 516
chr11_+_97050594 0.74 ENSMUST00000090020.5
oxysterol binding protein-like 7
chr1_+_165302625 0.71 ENSMUST00000111450.1
G protein-coupled receptor 161
chr11_+_97050811 0.70 ENSMUST00000168565.1
oxysterol binding protein-like 7
chr5_+_137761680 0.68 ENSMUST00000110983.2
TSC22 domain family, member 4
chr12_+_71015966 0.66 ENSMUST00000046305.5
AT rich interactive domain 4A (RBP1-like)
chr2_-_74578875 0.65 ENSMUST00000134168.1
limb and neural patterns
chrX_+_151046131 0.64 ENSMUST00000112685.1
FYVE, RhoGEF and PH domain containing 1
chr10_-_62507737 0.61 ENSMUST00000020271.6
chr19_+_29410919 0.58 ENSMUST00000112576.2
programmed cell death 1 ligand 2
chr6_-_56901870 0.55 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III
chr2_-_74579379 0.54 ENSMUST00000130586.1
limb and neural patterns
chr5_-_149051604 0.53 ENSMUST00000093196.4
high mobility group box 1
chr5_+_17574268 0.53 ENSMUST00000030568.7
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_144751968 0.51 ENSMUST00000155175.1
anoctamin 1, calcium activated chloride channel
chr7_+_102065713 0.49 ENSMUST00000094129.2
transient receptor potential cation channel, subfamily C, member 2
chr6_-_106745109 0.48 ENSMUST00000167925.2
interleukin 5 receptor, alpha
chr6_-_145047725 0.45 ENSMUST00000123930.1
branched chain aminotransferase 1, cytosolic
chr7_-_12422488 0.45 ENSMUST00000120220.1
zinc fingr protein 551
chr12_+_83632208 0.42 ENSMUST00000048155.9
RNA binding motif protein 25
chr3_-_146108047 0.40 ENSMUST00000160285.1
WD repeat domain 63
chr5_-_6876523 0.39 ENSMUST00000164784.1
zinc finger protein 804B
chrY_-_1286563 0.38 ENSMUST00000091190.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr4_-_59783800 0.38 ENSMUST00000107526.1
INTS3 and NABP interacting protein
chr19_-_56822161 0.37 ENSMUST00000118592.1
RIKEN cDNA A630007B06 gene
chr6_-_145047636 0.37 ENSMUST00000149769.1
branched chain aminotransferase 1, cytosolic
chr13_+_19342154 0.35 ENSMUST00000103566.3
T cell receptor gamma, constant 4
chrX_+_52791179 0.34 ENSMUST00000101588.1
coiled-coil domain containing 160
chr9_+_75775355 0.33 ENSMUST00000012281.7
bone morphogenetic protein 5
chr2_-_157337424 0.32 ENSMUST00000109536.1
growth hormone releasing hormone
chr13_-_55831378 0.28 ENSMUST00000021968.6
paired-like homeodomain transcription factor 1
chr2_-_155514796 0.26 ENSMUST00000029131.4
gamma-glutamyltransferase 7
chr16_-_52454074 0.25 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr7_+_118633729 0.25 ENSMUST00000057320.7
transmembrane channel-like gene family 5
chr8_-_60954726 0.23 ENSMUST00000110302.1
chloride channel 3
chr11_-_29825649 0.22 ENSMUST00000104962.1
RIKEN cDNA 4931440F15 gene
chr10_+_116143881 0.22 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr18_+_42275353 0.21 ENSMUST00000046972.7
RNA binding motif protein 27
chr8_-_27413937 0.19 ENSMUST00000033882.8
cholinergic receptor, nicotinic, alpha polypeptide 6
chr1_-_54195034 0.16 ENSMUST00000087659.4
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr9_+_113812547 0.16 ENSMUST00000166734.2
CLIP associating protein 2
chr10_+_128706251 0.14 ENSMUST00000054125.8
premelanosome protein
chr13_-_60897439 0.14 ENSMUST00000171347.1
cytotoxic T lymphocyte-associated protein 2 beta
chr15_+_81744848 0.14 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr7_+_116093296 0.14 ENSMUST00000032899.5
RIKEN cDNA 1110004F10 gene
chr17_+_24886643 0.11 ENSMUST00000117890.1
splA/ryanodine receptor domain and SOCS box containing 3
chr15_-_8710409 0.10 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_24097996 0.09 ENSMUST00000133787.1
neuropeptide S receptor 1
chr10_-_117238665 0.09 ENSMUST00000020392.4
RIKEN cDNA 9530003J23 gene
chr7_+_116093336 0.08 ENSMUST00000106608.1
RIKEN cDNA 1110004F10 gene
chr11_+_82045705 0.05 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr5_+_8798139 0.03 ENSMUST00000009058.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
chr15_+_101473472 0.03 ENSMUST00000088049.3
keratin 86
chr7_-_102759465 0.03 ENSMUST00000168007.1
olfactory receptor 78
chr4_+_155869540 0.00 ENSMUST00000120794.1
cleavage and polyadenylation specific factor 3-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 15.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.7 2.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.5 1.6 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.5 1.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.4 1.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3 1.1 GO:0070358 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.2 1.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 0.6 GO:0033371 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.1 0.8 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.3 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 0.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.0 GO:0006968 cellular defense response(GO:0006968)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 3.0 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 1.4 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 1.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 2.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.5 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.0 0.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.2 GO:0033603 positive regulation of dopamine secretion(GO:0033603)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0071914 prominosome(GO:0071914)
0.1 1.0 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 3.0 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0051373 FATZ binding(GO:0051373)
0.5 1.6 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.4 15.7 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.0 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.5 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 1.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 4.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling