avrg: GSE58827: Dynamics of the Mouse Liver


Results for ACUGGCC

Z-value: 0.46

Motif logo

miRNA associated with seed ACUGGCC

NamemiRBASE accession

Activity profile of ACUGGCC motif

Sorted Z-values of ACUGGCC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_84479418 1.46 ENSMUST00000091002.1
FH2 domain containing 1
chr10_-_128401218 1.31 ENSMUST00000042666.5
solute carrier family 39 (metal ion transporter), member 5
chr18_+_36528145 1.11 ENSMUST00000074298.6
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr4_+_13743424 0.73 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_3938354 0.55 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr11_-_96005872 0.45 ENSMUST00000013559.2
insulin-like growth factor 2 mRNA binding protein 1
chrX_+_9885622 0.39 ENSMUST00000067529.2
synaptotagmin-like 5
chr2_-_153241402 0.39 ENSMUST00000056924.7
pleiomorphic adenoma gene-like 2
chr4_+_17853451 0.38 ENSMUST00000029881.3
matrix metallopeptidase 16
chr10_-_62792243 0.34 ENSMUST00000020268.5
cell division cycle and apoptosis regulator 1
chr2_-_60963192 0.33 ENSMUST00000028347.6
RNA binding motif, single stranded interacting protein 1
chr17_+_8801742 0.33 ENSMUST00000089085.2
phosphodiesterase 10A
chr2_+_24367565 0.32 ENSMUST00000102942.1
pleckstrin and Sec7 domain containing 4
chr19_-_41802028 0.32 ENSMUST00000026150.8
Rho GTPase activating protein 19
chr2_+_121955964 0.32 ENSMUST00000036647.6
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr12_-_15816762 0.31 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr5_+_75574916 0.28 ENSMUST00000144270.1
kit oncogene
chr12_-_46818749 0.26 ENSMUST00000021438.6
neuro-oncological ventral antigen 1
chr11_-_49712674 0.25 ENSMUST00000020624.6
CCR4-NOT transcription complex, subunit 6
chr1_-_186705980 0.24 ENSMUST00000045288.8
transforming growth factor, beta 2
chr5_-_139325616 0.23 ENSMUST00000110865.1
ArfGAP with dual PH domains 1
chr19_+_45363734 0.22 ENSMUST00000065601.5
beta-transducin repeat containing protein
chr11_+_111066154 0.20 ENSMUST00000042970.2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_-_95228636 0.20 ENSMUST00000065482.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr11_-_98545800 0.20 ENSMUST00000103141.3
IKAROS family zinc finger 3
chr16_+_33684460 0.20 ENSMUST00000152782.1
HEG homolog 1 (zebrafish)
chr8_-_86745950 0.19 ENSMUST00000045296.4
seven in absentia 1A
chr2_-_140671462 0.19 ENSMUST00000110057.2
fibronectin leucine rich transmembrane protein 3
chr1_-_153332724 0.19 ENSMUST00000027752.8
laminin, gamma 1
chr12_-_69681795 0.17 ENSMUST00000183277.1
son of sevenless homolog 2 (Drosophila)
chr9_+_35421541 0.16 ENSMUST00000119129.2
cell adhesion molecule-related/down-regulated by oncogenes
chr5_-_107289561 0.16 ENSMUST00000031224.8
transforming growth factor, beta receptor III
chr3_-_153725062 0.16 ENSMUST00000064460.5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr6_-_39206782 0.14 ENSMUST00000002305.8
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_-_32854185 0.14 ENSMUST00000130134.2
proline rich 14-like
chr3_+_38886940 0.14 ENSMUST00000061260.7
FAT tumor suppressor homolog 4 (Drosophila)
chr19_+_53600377 0.14 ENSMUST00000025930.9
structural maintenance of chromosomes 3
chr16_+_20535475 0.14 ENSMUST00000090023.6
adaptor-related protein complex 2, mu 1 subunit
chr9_-_32541589 0.12 ENSMUST00000016231.7
Friend leukemia integration 1
chr1_-_152766281 0.12 ENSMUST00000111859.1
ral guanine nucleotide dissociation stimulator,-like 1
chr11_+_46055973 0.10 ENSMUST00000011400.7
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr10_+_69533761 0.10 ENSMUST00000182884.1
ankyrin 3, epithelial
chr9_+_113930934 0.10 ENSMUST00000084885.5
upstream binding protein 1
chr12_-_90738438 0.10 ENSMUST00000082432.3
deiodinase, iodothyronine, type II
chr9_+_32696005 0.09 ENSMUST00000034534.6
E26 avian leukemia oncogene 1, 5' domain
chr4_+_15881255 0.09 ENSMUST00000029876.1
calbindin 1
chr18_+_69345721 0.08 ENSMUST00000078486.6
transcription factor 4
chr18_+_78349754 0.08 ENSMUST00000164064.1
predicted gene 6133
chr3_+_152210458 0.08 ENSMUST00000166984.1
far upstream element (FUSE) binding protein 1
chr7_-_116237767 0.07 ENSMUST00000182834.1
pleckstrin homology domain containing, family A member 7
chr13_+_49341549 0.07 ENSMUST00000110084.2
bicaudal D homolog 2 (Drosophila)
chr9_+_106170918 0.07 ENSMUST00000020490.5
WD repeat domain containing 82
chr10_-_128891674 0.07 ENSMUST00000026408.6
growth differentiation factor 11
chr6_+_7844806 0.06 ENSMUST00000040159.4
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr6_-_145250177 0.06 ENSMUST00000111710.1
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr2_+_162931520 0.06 ENSMUST00000130411.1
serine/arginine-rich splicing factor 6
chr11_+_106036867 0.04 ENSMUST00000058438.8
DDB1 and CUL4 associated factor 7
chr11_-_94321957 0.04 ENSMUST00000166312.1
LUC7-like 3 (S. cerevisiae)
chr5_+_43868802 0.03 ENSMUST00000030964.4
CD38 antigen
chr11_+_107547925 0.03 ENSMUST00000100305.1
helicase with zinc finger domain
chr18_-_46280820 0.03 ENSMUST00000025354.3
protein geranylgeranyltransferase type I, beta subunit
chr10_+_128092771 0.02 ENSMUST00000170054.2
bromodomain adjacent to zinc finger domain, 2A
chr9_+_108795971 0.02 ENSMUST00000085018.4
inositol hexaphosphate kinase 2
chr1_+_93803945 0.02 ENSMUST00000027505.6
inhibitor of growth family, member 5
chr11_+_60537978 0.02 ENSMUST00000044250.3
alkB, alkylation repair homolog 5 (E. coli)
chr4_-_53159885 0.02 ENSMUST00000030010.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr13_-_93499803 0.01 ENSMUST00000065537.7
junction-mediating and regulatory protein
chr12_+_16810940 0.01 ENSMUST00000020908.7
E2F transcription factor 6
chr12_-_12941827 0.01 ENSMUST00000043396.7
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr1_+_43098710 0.01 ENSMUST00000010434.7
expressed sequence AI597479
chr12_-_79089623 0.01 ENSMUST00000072154.7
phosphatidylinositol glycan anchor biosynthesis, class H
chr4_+_155734800 0.01 ENSMUST00000147721.1
transmembrane protein 240
chr7_+_97579868 0.01 ENSMUST00000042399.7
remodeling and spacing factor 1
chr19_+_8819401 0.00 ENSMUST00000096753.3
heterogeneous nuclear ribonucleoprotein U-like 2
chr10_-_39133848 0.00 ENSMUST00000134279.1
family with sequence similarity 229, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of ACUGGCC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.3 GO:2000325 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac