Motif ID: ZNF8

Z-value: 0.300


Transcription factors associated with ZNF8:

Gene SymbolEntrez IDGene Name
ZNF8 ENSG00000083842.8 ZNF8
ZNF8 ENSG00000273439.1 ZNF8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_587903580.154.9e-01Click!


Activity profile for motif ZNF8.

activity profile for motif ZNF8


Sorted Z-values histogram for motif ZNF8

Sorted Z-values for motif ZNF8



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_13043697 0.675 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr6_+_88117683 0.430 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr6_+_29691198 0.323 ENST00000440587.2
ENST00000434407.2
HLA-F

major histocompatibility complex, class I, F

chr6_+_29691056 0.321 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F


major histocompatibility complex, class I, F


chr6_-_26056695 0.259 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr4_+_186347388 0.252 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr3_-_9994021 0.246 ENST00000411976.2
ENST00000412055.1
PRRT3

proline-rich transmembrane protein 3

chr9_+_1050331 0.211 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
DMRT2


doublesex and mab-3 related transcription factor 2


chr1_+_211500129 0.210 ENST00000427925.2
ENST00000261464.5
TRAF5

TNF receptor-associated factor 5

chr10_+_135192695 0.179 ENST00000368539.4
ENST00000278060.5
ENST00000357296.3
PAOX


polyamine oxidase (exo-N4-amino)


chr4_+_170541835 0.170 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr4_+_170541678 0.169 ENST00000360642.3
ENST00000512813.1
CLCN3

chloride channel, voltage-sensitive 3

chr11_-_46638720 0.141 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr6_+_18155560 0.140 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B


lysine (K)-specific demethylase 1B


chr1_-_186344802 0.134 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr11_+_13690249 0.124 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr1_-_55266865 0.110 ENST00000371274.4
TTC22
tetratricopeptide repeat domain 22
chr9_+_96026230 0.109 ENST00000448251.1
WNK2
WNK lysine deficient protein kinase 2
chr4_+_170541660 0.109 ENST00000513761.1
ENST00000347613.4
CLCN3

chloride channel, voltage-sensitive 3

chr5_-_137911049 0.106 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr16_+_29973351 0.106 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
TMEM219



transmembrane protein 219



chr5_-_93447333 0.106 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A


family with sequence similarity 172, member A


chr1_-_55266926 0.105 ENST00000371276.4
TTC22
tetratricopeptide repeat domain 22
chr5_+_10353780 0.100 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6


membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase


chr9_-_37576226 0.093 ENST00000432825.2
FBXO10
F-box protein 10
chr22_-_37415475 0.086 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
TST


thiosulfate sulfurtransferase (rhodanese)


chr19_-_55652290 0.081 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr1_+_186344945 0.080 ENST00000419367.3
ENST00000287859.6
C1orf27

chromosome 1 open reading frame 27

chr1_+_186344883 0.078 ENST00000367470.3
C1orf27
chromosome 1 open reading frame 27
chr7_+_117824086 0.066 ENST00000249299.2
ENST00000424702.1
NAA38

N(alpha)-acetyltransferase 38, NatC auxiliary subunit

chr2_-_105946491 0.065 ENST00000393359.2
TGFBRAP1
transforming growth factor, beta receptor associated protein 1
chr10_-_1034237 0.065 ENST00000381466.1
AL359878.1
Uncharacterized protein
chr10_+_1034338 0.062 ENST00000360803.4
ENST00000538293.1
GTPBP4

GTP binding protein 4

chr17_+_34136459 0.059 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15





TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa





chr17_+_75181292 0.051 ENST00000431431.2
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr17_+_7517264 0.051 ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
ENST00000593717.1
SHBG






AC007421.1
sex hormone-binding globulin






AC007421.1
chr20_+_37377085 0.050 ENST00000243903.4
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr13_+_53226963 0.048 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1


SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)


chr2_-_240322643 0.042 ENST00000345617.3
HDAC4
histone deacetylase 4
chr15_+_85523671 0.037 ENST00000310298.4
ENST00000557957.1
PDE8A

phosphodiesterase 8A

chr1_+_25664408 0.036 ENST00000374358.4
TMEM50A
transmembrane protein 50A
chr6_-_31763408 0.034 ENST00000444930.2
VARS
valyl-tRNA synthetase
chr11_+_46638805 0.031 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
ATG13


autophagy related 13


chrX_+_102631248 0.030 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr1_+_214161272 0.028 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr19_+_52074502 0.024 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175


zinc finger protein 175


chr12_-_74686314 0.021 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2


RP11-81H3.2


chr13_+_21750780 0.020 ENST00000309594.4
MRP63
mitochondrial ribosomal protein 63
chr16_+_68573116 0.020 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
ZFP90




ZFP90 zinc finger protein




chr10_-_73611046 0.020 ENST00000394934.1
ENST00000394936.3
PSAP

prosaposin

chr11_+_13690200 0.019 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr19_+_35739897 0.017 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR


lipolysis stimulated lipoprotein receptor


chr1_-_246670519 0.016 ENST00000388985.4
ENST00000490107.1
SMYD3

SET and MYND domain containing 3

chr2_+_198365122 0.014 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr19_+_37998031 0.014 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
ZNF793


zinc finger protein 793


chr12_+_52463751 0.013 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
C12orf44



chromosome 12 open reading frame 44



chr7_+_100303676 0.013 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr12_+_79258444 0.013 ENST00000261205.4
SYT1
synaptotagmin I
chr1_+_6615241 0.012 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1


taste receptor, type 1, member 1


chr2_+_87144738 0.012 ENST00000559485.1
RGPD1
RANBP2-like and GRIP domain containing 1
chr1_-_228296956 0.010 ENST00000366744.1
ENST00000348259.5
ENST00000366747.3
ENST00000366746.3
ENST00000295008.4
ENST00000336520.3
ENST00000366731.5
ENST00000411464.2
ENST00000457264.1
ENST00000336300.5
ENST00000430433.1
ENST00000391867.3
MRPL55











mitochondrial ribosomal protein L55











chr13_+_45563721 0.009 ENST00000361121.2
GPALPP1
GPALPP motifs containing 1
chr19_+_35739782 0.009 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr6_-_116601044 0.008 ENST00000368608.3
TSPYL1
TSPY-like 1
chrX_+_128913906 0.008 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr22_+_30163340 0.008 ENST00000330029.6
ENST00000401406.3
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr5_+_89854595 0.007 ENST00000405460.2
GPR98
G protein-coupled receptor 98
chr12_+_79258547 0.006 ENST00000457153.2
SYT1
synaptotagmin I
chr17_+_48585745 0.006 ENST00000323776.5
MYCBPAP
MYCBP associated protein
chr5_+_102455968 0.004 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr16_+_21964662 0.004 ENST00000561553.1
ENST00000565331.1
UQCRC2

ubiquinol-cytochrome c reductase core protein II

chr2_+_172290707 0.004 ENST00000375255.3
ENST00000539783.1
DCAF17

DDB1 and CUL4 associated factor 17

chr11_-_61560254 0.003 ENST00000543510.1
TMEM258
transmembrane protein 258
chr6_+_53659746 0.002 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr8_-_109260897 0.002 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E





eukaryotic translation initiation factor 3, subunit E





chr3_+_49236910 0.000 ENST00000452691.2
ENST00000366429.2
CCDC36

coiled-coil domain containing 36


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0032240 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.7 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation