Motif ID: ZNF8

Z-value: 0.300


Transcription factors associated with ZNF8:

Gene SymbolEntrez IDGene Name
ZNF8 ENSG00000083842.8 ZNF8
ZNF8 ENSG00000273439.1 ZNF8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_587903580.154.9e-01Click!


Activity profile for motif ZNF8.

activity profile for motif ZNF8


Sorted Z-values histogram for motif ZNF8

Sorted Z-values for motif ZNF8



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF8

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_13043697 0.675 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr6_+_88117683 0.430 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr6_+_29691198 0.323 ENST00000440587.2
ENST00000434407.2
HLA-F

major histocompatibility complex, class I, F

chr6_+_29691056 0.321 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F


major histocompatibility complex, class I, F


chr6_-_26056695 0.259 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr4_+_186347388 0.252 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr3_-_9994021 0.246 ENST00000411976.2
ENST00000412055.1
PRRT3

proline-rich transmembrane protein 3

chr9_+_1050331 0.211 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
DMRT2


doublesex and mab-3 related transcription factor 2


chr1_+_211500129 0.210 ENST00000427925.2
ENST00000261464.5
TRAF5

TNF receptor-associated factor 5

chr10_+_135192695 0.179 ENST00000368539.4
ENST00000278060.5
ENST00000357296.3
PAOX


polyamine oxidase (exo-N4-amino)


chr4_+_170541835 0.170 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr4_+_170541678 0.169 ENST00000360642.3
ENST00000512813.1
CLCN3

chloride channel, voltage-sensitive 3

chr11_-_46638720 0.141 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr6_+_18155560 0.140 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B


lysine (K)-specific demethylase 1B


chr1_-_186344802 0.134 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr11_+_13690249 0.124 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr1_-_55266865 0.110 ENST00000371274.4
TTC22
tetratricopeptide repeat domain 22
chr9_+_96026230 0.109 ENST00000448251.1
WNK2
WNK lysine deficient protein kinase 2
chr4_+_170541660 0.109 ENST00000513761.1
ENST00000347613.4
CLCN3

chloride channel, voltage-sensitive 3

chr5_-_137911049 0.106 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0032240 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation