Motif ID: ZNF274

Z-value: 0.318


Transcription factors associated with ZNF274:

Gene SymbolEntrez IDGene Name
ZNF274 ENSG00000171606.13 ZNF274

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF274hg19_v2_chr19_+_58694396_58694485-0.174.4e-01Click!


Activity profile for motif ZNF274.

activity profile for motif ZNF274


Sorted Z-values histogram for motif ZNF274

Sorted Z-values for motif ZNF274



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF274

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45205498 0.672 ENST00000372218.4
KIF2C
kinesin family member 2C
chr1_+_45205478 0.667 ENST00000452259.1
ENST00000372224.4
KIF2C

kinesin family member 2C

chr12_-_54653313 0.329 ENST00000550411.1
ENST00000439541.2
CBX5

chromobox homolog 5

chr2_+_11864458 0.304 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1


lipin 1


chr6_+_31553901 0.272 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1



leukocyte specific transcript 1



chr6_+_31553978 0.248 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1


leukocyte specific transcript 1


chr2_-_42991257 0.246 ENST00000378661.2
OXER1
oxoeicosanoid (OXE) receptor 1
chr16_+_29818857 0.242 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_+_30687978 0.239 ENST00000327892.8
ENST00000435534.1
TUBB

tubulin, beta class I

chr12_+_113344755 0.229 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_+_60174827 0.228 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr22_+_39353527 0.227 ENST00000249116.2
APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr11_+_55653396 0.225 ENST00000244891.3
TRIM51
tripartite motif-containing 51
chr17_-_41132410 0.223 ENST00000409399.1
ENST00000421990.2
ENST00000409446.3
ENST00000453594.1
PTGES3L-AARSD1

PTGES3L

PTGES3L-AARSD1 readthrough

prostaglandin E synthase 3 (cytosolic)-like

chr18_+_9885760 0.214 ENST00000536353.2
ENST00000584255.1
TXNDC2

thioredoxin domain containing 2 (spermatozoa)

chr14_+_22409308 0.193 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr11_-_10590118 0.183 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_32784687 0.174 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr2_-_89292422 0.163 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr12_+_109273806 0.163 ENST00000228476.3
ENST00000547768.1
DAO

D-amino-acid oxidase

chr16_-_80603558 0.157 ENST00000567317.1
RP11-18F14.1
RP11-18F14.1
chr8_-_4852494 0.155 ENST00000520002.1
ENST00000602557.1
CSMD1

CUB and Sushi multiple domains 1

chr3_+_102153859 0.153 ENST00000306176.1
ENST00000466937.1
ZPLD1

zona pellucida-like domain containing 1

chr19_+_6887571 0.149 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1




egf-like module containing, mucin-like, hormone receptor-like 1




chr8_-_4852218 0.144 ENST00000400186.3
ENST00000602723.1
CSMD1

CUB and Sushi multiple domains 1

chr6_+_36165133 0.131 ENST00000446974.1
ENST00000454960.1
BRPF3

bromodomain and PHD finger containing, 3

chr18_+_9885961 0.130 ENST00000306084.6
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr18_+_9885934 0.129 ENST00000357775.5
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr14_-_24047965 0.127 ENST00000397118.3
ENST00000356300.4
JPH4

junctophilin 4

chr10_-_29811456 0.115 ENST00000535393.1
SVIL
supervillin
chr5_+_32531893 0.105 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr10_+_5488564 0.097 ENST00000449083.1
ENST00000380359.3
NET1

neuroepithelial cell transforming 1

chr16_+_29819096 0.092 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MAZ


MYC-associated zinc finger protein (purine-binding transcription factor)


chr15_+_89164520 0.087 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr5_-_74162605 0.071 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A


family with sequence similarity 169, member A


chr16_+_31470179 0.070 ENST00000538189.1
ENST00000268314.4
ARMC5

armadillo repeat containing 5

chr19_+_6135646 0.068 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2






acyl-CoA synthetase bubblegum family member 2






chr16_+_29819446 0.064 ENST00000568282.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_31470143 0.062 ENST00000457010.2
ENST00000563544.1
ARMC5

armadillo repeat containing 5

chrX_+_52920336 0.062 ENST00000452154.2
FAM156B
family with sequence similarity 156, member B
chr16_+_29819372 0.061 ENST00000568544.1
ENST00000569978.1
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chrX_+_119737806 0.051 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr3_+_50284321 0.047 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr1_+_42928945 0.043 ENST00000428554.2
CCDC30
coiled-coil domain containing 30
chr19_+_40195101 0.043 ENST00000360675.3
ENST00000601802.1
LGALS14

lectin, galactoside-binding, soluble, 14

chr19_+_40194946 0.036 ENST00000392052.3
LGALS14
lectin, galactoside-binding, soluble, 14
chr22_+_24038593 0.034 ENST00000452208.1
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr7_+_30791743 0.032 ENST00000013222.5
ENST00000409539.1
INMT

indolethylamine N-methyltransferase

chr4_-_121993673 0.031 ENST00000379692.4
NDNF
neuron-derived neurotrophic factor
chr17_-_3461092 0.016 ENST00000301365.4
ENST00000572519.1
TRPV3

transient receptor potential cation channel, subfamily V, member 3

chr2_+_9696028 0.011 ENST00000607241.1
RP11-214N9.1
RP11-214N9.1
chr19_+_41949054 0.004 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.5 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors