Motif ID: ZKSCAN1

Z-value: 0.784


Transcription factors associated with ZKSCAN1:

Gene SymbolEntrez IDGene Name
ZKSCAN1 ENSG00000106261.12 ZKSCAN1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg19_v2_chr7_+_99613195_99613206-0.611.7e-03Click!


Activity profile for motif ZKSCAN1.

activity profile for motif ZKSCAN1


Sorted Z-values histogram for motif ZKSCAN1

Sorted Z-values for motif ZKSCAN1



Network of associatons between targets according to the STRING database.



First level regulatory network of ZKSCAN1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_135394840 3.930 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr12_+_4385230 3.798 ENST00000536537.1
CCND2
cyclin D2
chr22_-_37640456 3.627 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2


ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)


chr22_-_37640277 3.441 ENST00000401529.3
ENST00000249071.6
RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

chr11_-_58343319 2.564 ENST00000395074.2
LPXN
leupaxin
chr9_+_126131131 2.384 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr1_-_205391178 2.218 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr19_-_19051993 1.985 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3



homer homolog 3 (Drosophila)



chr11_-_568369 1.981 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr12_-_25055177 1.884 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr9_-_123639445 1.613 ENST00000312189.6
PHF19
PHD finger protein 19
chr1_+_209859510 1.590 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr1_-_149908217 1.476 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr9_+_103189660 1.366 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr5_-_127873659 1.353 ENST00000262464.4
FBN2
fibrillin 2
chr9_-_123639600 1.319 ENST00000373896.3
PHF19
PHD finger protein 19
chr19_-_55660561 1.301 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1






troponin T type 1 (skeletal, slow)






chr9_+_103189536 1.222 ENST00000374885.1
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr1_+_65613340 1.220 ENST00000546702.1
AK4
adenylate kinase 4
chrX_+_47441712 1.065 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1




TIMP metallopeptidase inhibitor 1




chr1_+_16083154 1.023 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr20_-_48770244 1.007 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189


transmembrane protein 189


chr5_+_149980622 0.975 ENST00000394243.1
SYNPO
synaptopodin
chr22_+_33197683 0.958 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr20_-_56265680 0.951 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr11_+_72975559 0.948 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_72975524 0.928 ENST00000540342.1
ENST00000542092.1
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr11_+_72975578 0.913 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr14_-_96743060 0.904 ENST00000554299.1
DKFZP434O1614
DKFZP434O1614
chr2_+_74120094 0.858 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2




actin, gamma 2, smooth muscle, enteric




chr16_-_19729502 0.831 ENST00000219837.7
KNOP1
lysine-rich nucleolar protein 1
chr1_+_65613217 0.805 ENST00000545314.1
AK4
adenylate kinase 4
chr10_-_76859247 0.679 ENST00000472493.2
ENST00000605915.1
ENST00000478873.2
DUSP13


dual specificity phosphatase 13


chr3_+_12329397 0.628 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr17_-_73150599 0.616 ENST00000392566.2
ENST00000581874.1
HN1

hematological and neurological expressed 1

chr20_+_43343476 0.608 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr22_+_20861858 0.604 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15







mediator complex subunit 15







chr3_+_12329358 0.598 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr5_-_131562935 0.591 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr1_-_155224751 0.581 ENST00000350210.2
ENST00000368368.3
FAM189B

family with sequence similarity 189, member B

chr19_+_39138271 0.557 ENST00000252699.2
ACTN4
actinin, alpha 4
chr8_-_131028869 0.537 ENST00000518283.1
ENST00000519110.1
FAM49B

family with sequence similarity 49, member B

chr20_+_43343517 0.504 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr12_+_8995832 0.489 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr15_-_34635314 0.483 ENST00000557912.1
ENST00000328848.4
NOP10

NOP10 ribonucleoprotein

chr7_+_73588575 0.471 ENST00000265753.8
EIF4H
eukaryotic translation initiation factor 4H
chr11_-_118134997 0.454 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr19_+_850985 0.453 ENST00000590230.1
ELANE
elastase, neutrophil expressed
chr7_+_73588665 0.444 ENST00000353999.6
EIF4H
eukaryotic translation initiation factor 4H
chr10_+_89420706 0.443 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr20_+_4152356 0.427 ENST00000379460.2
SMOX
spermine oxidase
chr5_-_172756506 0.419 ENST00000265087.4
STC2
stanniocalcin 2
chr2_+_27070964 0.409 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr17_+_75372165 0.406 ENST00000427674.2
SEPT9
septin 9
chr14_+_103851712 0.390 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3



MAP/microtubule affinity-regulating kinase 3



chr18_+_52495426 0.366 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr17_-_46716647 0.365 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr19_-_344786 0.362 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr19_+_13051206 0.360 ENST00000586760.1
CALR
calreticulin
chr9_+_132934835 0.344 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr16_-_838329 0.341 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1





RNA pseudouridylate synthase domain containing 1





chr16_+_67562702 0.341 ENST00000379312.3
ENST00000042381.4
ENST00000540839.3
FAM65A


family with sequence similarity 65, member A


chr12_-_123450986 0.336 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9




ATP-binding cassette, sub-family B (MDR/TAP), member 9




chr11_+_70049269 0.322 ENST00000301838.4
FADD
Fas (TNFRSF6)-associated via death domain
chr15_+_89921280 0.311 ENST00000560596.1
ENST00000558692.1
ENST00000538734.2
ENST00000559235.1
LINC00925



long intergenic non-protein coding RNA 925



chr19_+_39138320 0.304 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4


actinin, alpha 4


chr6_+_35265586 0.303 ENST00000542066.1
ENST00000316637.5
DEF6

differentially expressed in FDCP 6 homolog (mouse)

chr11_+_33563821 0.301 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L


KIAA1549-like


chr10_-_126432821 0.296 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chrX_-_15402498 0.294 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr2_+_27071045 0.292 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr1_+_16348366 0.291 ENST00000375692.1
ENST00000420078.1
CLCNKA

chloride channel, voltage-sensitive Ka

chr7_-_72742085 0.272 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr12_+_122326630 0.268 ENST00000541212.1
ENST00000340175.5
PSMD9

proteasome (prosome, macropain) 26S subunit, non-ATPase, 9

chr1_+_226411319 0.266 ENST00000542034.1
ENST00000366810.5
MIXL1

Mix paired-like homeobox

chr22_+_21921994 0.257 ENST00000545681.1
UBE2L3
ubiquitin-conjugating enzyme E2L 3
chrX_-_130423200 0.250 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr16_+_56899114 0.250 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3



solute carrier family 12 (sodium/chloride transporter), member 3



chr17_-_73150629 0.247 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1


hematological and neurological expressed 1


chr7_+_72742178 0.243 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6


FK506 binding protein 6, 36kDa


chr11_+_64808675 0.237 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr6_-_30640811 0.228 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr12_+_122326662 0.226 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9


proteasome (prosome, macropain) 26S subunit, non-ATPase, 9


chr4_+_39460620 0.226 ENST00000340169.2
ENST00000261434.3
LIAS

lipoic acid synthetase

chr7_+_72742162 0.221 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chrX_-_130423386 0.221 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr1_+_113009163 0.220 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr19_-_38916839 0.213 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4




RAS guanyl releasing protein 4




chr3_+_184081213 0.211 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr3_+_184081175 0.211 ENST00000452961.1
ENST00000296223.3
POLR2H

polymerase (RNA) II (DNA directed) polypeptide H

chr9_-_86153218 0.209 ENST00000304195.3
ENST00000376438.1
FRMD3

FERM domain containing 3

chr15_+_75498739 0.203 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr15_-_80215984 0.192 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr21_+_46066331 0.180 ENST00000334670.8
KRTAP10-11
keratin associated protein 10-11
chr15_-_49103184 0.179 ENST00000399334.3
ENST00000325747.5
CEP152

centrosomal protein 152kDa

chr5_-_134735568 0.177 ENST00000510038.1
ENST00000304332.4
H2AFY

H2A histone family, member Y

chr13_+_76445187 0.169 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr12_+_52400719 0.167 ENST00000293662.4
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr3_-_64673289 0.166 ENST00000295903.4
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr4_+_39460659 0.162 ENST00000513731.1
LIAS
lipoic acid synthetase
chr19_+_18794470 0.155 ENST00000321949.8
ENST00000338797.6
CRTC1

CREB regulated transcription coactivator 1

chr19_-_38916822 0.155 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr6_-_43276535 0.149 ENST00000372569.3
ENST00000274990.4
CRIP3

cysteine-rich protein 3

chr7_+_87563557 0.147 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22





ADAM metallopeptidase domain 22





chr6_+_36922209 0.142 ENST00000373674.3
PI16
peptidase inhibitor 16
chr5_+_137774706 0.141 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2


receptor accessory protein 2


chr14_-_76447336 0.135 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr1_+_32083301 0.132 ENST00000403528.2
HCRTR1
hypocretin (orexin) receptor 1
chr2_-_37193606 0.131 ENST00000379213.2
ENST00000263918.4
STRN

striatin, calmodulin binding protein

chr11_+_46366918 0.115 ENST00000528615.1
ENST00000395574.3
DGKZ

diacylglycerol kinase, zeta

chr4_+_39460689 0.115 ENST00000381846.1
LIAS
lipoic acid synthetase
chr19_+_3178736 0.111 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr8_+_22102626 0.105 ENST00000519237.1
ENST00000397802.4
POLR3D

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

chr11_-_61197480 0.096 ENST00000439958.3
ENST00000394888.4
CPSF7

cleavage and polyadenylation specific factor 7, 59kDa

chrX_+_150866779 0.092 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr11_-_73720276 0.090 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr2_-_158345462 0.087 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr20_+_36932521 0.085 ENST00000262865.4
BPI
bactericidal/permeability-increasing protein
chr17_-_26684473 0.079 ENST00000540200.1
POLDIP2
polymerase (DNA-directed), delta interacting protein 2
chr9_+_138413277 0.074 ENST00000263598.2
ENST00000371781.3
LCN1

lipocalin 1

chr5_+_155753745 0.074 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr10_+_23384435 0.067 ENST00000376510.3
MSRB2
methionine sulfoxide reductase B2
chr21_+_18811205 0.064 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr2_+_113931513 0.052 ENST00000245796.6
ENST00000441564.3
PSD4

pleckstrin and Sec7 domain containing 4

chr17_+_17685422 0.052 ENST00000395774.1
RAI1
retinoic acid induced 1
chr3_+_184081137 0.047 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_5031687 0.043 ENST00000250066.6
ENST00000304328.5
USP6

ubiquitin specific peptidase 6 (Tre-2 oncogene)

chr20_-_3644046 0.040 ENST00000290417.2
ENST00000319242.3
GFRA4

GDNF family receptor alpha 4

chr1_+_27648648 0.036 ENST00000374076.4
TMEM222
transmembrane protein 222
chr16_+_19125252 0.034 ENST00000566735.1
ENST00000381440.3
ITPRIPL2

inositol 1,4,5-trisphosphate receptor interacting protein-like 2

chr11_-_64739542 0.033 ENST00000536065.1
C11orf85
chromosome 11 open reading frame 85
chr19_-_50666404 0.032 ENST00000600293.1
IZUMO2
IZUMO family member 2
chr6_-_33160231 0.032 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chr4_-_176733897 0.027 ENST00000393658.2
GPM6A
glycoprotein M6A
chr10_-_88281494 0.027 ENST00000298767.5
WAPAL
wings apart-like homolog (Drosophila)
chr2_+_1488435 0.026 ENST00000446278.1
ENST00000469607.1
TPO

thyroid peroxidase

chr10_+_112679301 0.022 ENST00000265277.5
ENST00000369452.4
SHOC2

soc-2 suppressor of clear homolog (C. elegans)

chr1_+_27648709 0.019 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
TMEM222



transmembrane protein 222



chr1_-_36615065 0.016 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3


trafficking protein particle complex 3


chr19_-_2739992 0.014 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3


solute carrier family 39 (zinc transporter), member 3


chr19_-_50666431 0.012 ENST00000293405.3
IZUMO2
IZUMO family member 2
chr2_-_183387430 0.010 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.4 2.4 GO:0014028 notochord formation(GO:0014028)
0.3 2.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 1.9 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 1.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.3 0.9 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 2.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 1.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 1.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 2.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 2.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 0.5 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.2 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 3.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.9 GO:0090131 mesenchyme migration(GO:0090131)
0.1 1.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.5 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 2.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:1903238 neutrophil mediated killing of gram-negative bacterium(GO:0070945) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.4 GO:0046208 spermine catabolic process(GO:0046208)
0.1 1.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.2 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 3.8 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.0 GO:0097444 spine apparatus(GO:0097444)
0.1 3.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 7.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.3 GO:0005861 troponin complex(GO:0005861)
0.1 1.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.6 GO:0002102 podosome(GO:0002102)
0.0 5.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088) zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.7 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 2.8 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.4 2.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 1.9 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.9 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.2 0.5 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.2 1.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.4 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.3 GO:0031014 troponin T binding(GO:0031014)
0.1 0.5 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 3.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 6.3 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.0 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.9 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 3.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 2.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.8 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 1.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 3.9 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.2 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 1.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules