Motif ID: ZFX
Z-value: 1.170

Transcription factors associated with ZFX:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
ZFX | ENSG00000005889.11 | ZFX |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
ZFX | hg19_v2_chrX_+_24167828_24167907 | 0.51 | 1.0e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 471 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.8 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.1 | 2.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 2.3 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 2.2 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
0.1 | 1.8 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 1.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.2 | 1.6 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.1 | 1.6 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 1.6 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.0 | 1.6 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
0.5 | 1.4 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
0.2 | 1.4 | GO:0035803 | egg coat formation(GO:0035803) |
0.0 | 1.4 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
0.4 | 1.3 | GO:1903519 | apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
0.2 | 1.3 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
0.0 | 1.3 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
0.1 | 1.2 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.0 | 1.2 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
0.0 | 1.2 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.1 | 1.1 | GO:0002934 | desmosome organization(GO:0002934) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 184 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 6.5 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 2.5 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 2.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 2.2 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 2.1 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.1 | 1.9 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 1.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.1 | 1.8 | GO:0030056 | hemidesmosome(GO:0030056) |
0.3 | 1.7 | GO:0005927 | muscle tendon junction(GO:0005927) |
0.0 | 1.7 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.2 | 1.5 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.1 | 1.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 1.5 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.5 | 1.4 | GO:0016938 | kinesin I complex(GO:0016938) |
0.3 | 1.4 | GO:0035838 | growing cell tip(GO:0035838) |
0.1 | 1.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 1.4 | GO:0000502 | proteasome complex(GO:0000502) |
0.0 | 1.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.1 | 1.1 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 1.0 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 324 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.0 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 4.0 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 3.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 2.5 | GO:0051015 | actin filament binding(GO:0051015) |
0.1 | 2.3 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.2 | 2.2 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
0.0 | 2.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.2 | 1.9 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 1.7 | GO:0019209 | kinase activator activity(GO:0019209) |
0.5 | 1.6 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.0 | 1.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.4 | 1.4 | GO:0004461 | lactose synthase activity(GO:0004461) |
0.3 | 1.4 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
0.1 | 1.4 | GO:0032190 | acrosin binding(GO:0032190) |
0.1 | 1.4 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 1.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 1.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.0 | 1.3 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.1 | 1.2 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 47 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.6 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 3.8 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.1 | 2.8 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 2.3 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 2.1 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 2.0 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 1.9 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 1.6 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 1.5 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 1.3 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 1.2 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 1.1 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.1 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 1.1 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 1.0 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 1.0 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.0 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 1.0 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 1.0 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.9 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 85 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.9 | REACTOME_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell junction organization |
0.1 | 2.8 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 2.3 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 2.2 | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
0.0 | 2.1 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
0.0 | 1.8 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 1.6 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
0.0 | 1.6 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 1.5 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 1.5 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 1.4 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.1 | 1.4 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 1.3 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 1.2 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 1.2 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | Genes involved in Downstream signal transduction |
0.0 | 1.1 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.9 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.9 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.9 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |