Motif ID: ZBTB33_CHD2

Z-value: 2.232

Transcription factors associated with ZBTB33_CHD2:

Gene SymbolEntrez IDGene Name
CHD2 ENSG00000173575.14 CHD2
ZBTB33 ENSG00000177485.6 ZBTB33

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB33hg19_v2_chrX_+_119384607_1193847200.691.9e-04Click!
CHD2hg19_v2_chr15_+_93443419_93443580-0.537.2e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB33_CHD2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_7761013 21.809 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr17_+_7761301 17.924 ENST00000332439.4
ENST00000570446.1
CYB5D1

cytochrome b5 domain containing 1

chr10_-_75118611 7.793 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
TTC18



tetratricopeptide repeat domain 18



chr22_+_45809560 7.732 ENST00000342894.3
ENST00000538017.1
RIBC2

RIB43A domain with coiled-coils 2

chr10_-_75118471 7.714 ENST00000340329.3
TTC18
tetratricopeptide repeat domain 18
chr3_+_108308513 7.283 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr2_-_207629997 7.225 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chrX_+_53449887 7.222 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr2_-_207630033 6.864 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr2_-_99757977 6.798 ENST00000355053.4
TSGA10
testis specific, 10
chr15_+_75287861 6.273 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5







secretory carrier membrane protein 5







chrY_+_15016725 5.943 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr11_+_71791849 5.083 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT




leucine rich transmembrane and O-methyltransferase domain containing




chr17_+_7591639 5.009 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr2_-_99757876 4.844 ENST00000539964.1
ENST00000393482.3
TSGA10

testis specific, 10

chrX_+_53449805 4.826 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr17_+_7591747 4.516 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr15_-_56757329 4.450 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr15_+_22833395 4.253 ENST00000283645.4
TUBGCP5
tubulin, gamma complex associated protein 5
chr4_-_17812309 4.109 ENST00000382247.1
ENST00000536863.1
DCAF16

DDB1 and CUL4 associated factor 16

chr11_+_71791693 4.055 ENST00000289488.2
ENST00000447974.1
LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr15_-_48470544 3.861 ENST00000267836.6
MYEF2
myelin expression factor 2
chr11_+_71791803 3.832 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_93781750 3.484 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr15_+_22833482 3.293 ENST00000453949.2
TUBGCP5
tubulin, gamma complex associated protein 5
chr6_+_116937636 3.238 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr16_+_89724188 3.204 ENST00000301031.4
ENST00000566204.1
ENST00000579310.1
SPATA33


spermatogenesis associated 33


chrY_+_15016013 3.135 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr4_-_16085340 3.033 ENST00000508167.1
PROM1
prominin 1
chr4_-_16085314 3.003 ENST00000510224.1
PROM1
prominin 1
chr16_+_89724434 2.997 ENST00000568929.1
SPATA33
spermatogenesis associated 33
chr20_-_61569227 2.983 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
DIDO1


death inducer-obliterator 1


chr2_-_55844720 2.896 ENST00000345102.5
ENST00000272313.5
ENST00000407823.3
SMEK2


SMEK homolog 2, suppressor of mek1 (Dictyostelium)


chr1_-_24741525 2.847 ENST00000374409.1
STPG1
sperm-tail PG-rich repeat containing 1
chr9_+_86595626 2.783 ENST00000445877.1
ENST00000325875.3
RMI1

RecQ mediated genome instability 1

chr6_+_52285131 2.782 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr16_+_89724263 2.758 ENST00000564238.1
SPATA33
spermatogenesis associated 33
chr8_-_110704014 2.733 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU


syntabulin (syntaxin-interacting)


chr16_+_90089008 2.713 ENST00000268699.4
GAS8
growth arrest-specific 8
chr10_+_96305535 2.686 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS




helicase, lymphoid-specific




chr20_-_34330129 2.630 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39




RNA binding motif protein 39




chr1_-_207224307 2.418 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr13_+_24153488 2.410 ENST00000382258.4
ENST00000382263.3
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr2_-_677369 2.286 ENST00000281017.3
TMEM18
transmembrane protein 18
chr2_-_43823093 2.283 ENST00000405006.4
THADA
thyroid adenoma associated
chr1_-_167906020 2.244 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr11_-_118436707 2.213 ENST00000264020.2
ENST00000264021.3
IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chr15_-_48470558 2.192 ENST00000324324.7
MYEF2
myelin expression factor 2
chr11_-_118436606 2.057 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr4_+_40751914 2.055 ENST00000381782.2
ENST00000316607.5
NSUN7

NOP2/Sun domain family, member 7

chr9_+_26956371 2.048 ENST00000380062.5
ENST00000518614.1
IFT74

intraflagellar transport 74 homolog (Chlamydomonas)

chr10_-_28287968 2.020 ENST00000305242.5
ARMC4
armadillo repeat containing 4
chr1_+_19923454 1.973 ENST00000322753.6
ENST00000602662.1
ENST00000602293.1
MINOS1
MINOS1-NBL1

mitochondrial inner membrane organizing system 1
MINOS1-NBL1 readthrough

chr1_-_167906277 1.965 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr8_-_42698433 1.949 ENST00000345117.2
ENST00000254250.3
THAP1

THAP domain containing, apoptosis associated protein 1

chr12_+_56661033 1.939 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr11_+_71791359 1.921 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr8_-_110703819 1.890 ENST00000532779.1
ENST00000534578.1
SYBU

syntabulin (syntaxin-interacting)

chr3_-_160117301 1.888 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr10_+_127408263 1.869 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr16_+_14165160 1.799 ENST00000574998.1
ENST00000571589.1
ENST00000574045.1
MKL2


MKL/myocardin-like 2


chr15_-_64126084 1.752 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1




HECT and RLD domain containing E3 ubiquitin protein ligase family member 1




chrX_+_77154935 1.718 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr16_-_84150492 1.700 ENST00000343411.3
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr13_+_115047097 1.684 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr1_-_174992544 1.672 ENST00000476371.1
MRPS14
mitochondrial ribosomal protein S14
chr1_+_70820451 1.636 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3




HERV-H LTR-associating 3




chr22_+_23487513 1.581 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr8_+_75896731 1.575 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr1_-_59165763 1.525 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr2_-_25194963 1.525 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr3_-_137893721 1.519 ENST00000505015.2
ENST00000260803.4
DBR1

debranching RNA lariats 1

chr13_+_115047053 1.516 ENST00000375299.3
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr13_-_21750659 1.492 ENST00000400018.3
ENST00000314759.5
SKA3

spindle and kinetochore associated complex subunit 3

chr9_-_21031608 1.485 ENST00000513293.2
ENST00000495827.2
PTPLAD2

protein tyrosine phosphatase-like A domain containing 2

chr6_+_52285046 1.474 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr5_-_10249990 1.470 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B


family with sequence similarity 173, member B


chr16_+_57481382 1.465 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
COQ9



coenzyme Q9



chr1_+_231473743 1.462 ENST00000295050.7
SPRTN
SprT-like N-terminal domain
chr1_+_20512568 1.446 ENST00000375099.3
UBXN10
UBX domain protein 10
chr1_+_26146397 1.436 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L








mitochondrial fission regulator 1-like








chr6_-_43478239 1.431 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr1_+_3569129 1.410 ENST00000354437.4
ENST00000357733.3
ENST00000346387.4
TP73


tumor protein p73


chr2_-_241497374 1.404 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ANKMY1



ankyrin repeat and MYND domain containing 1



chr1_+_26146674 1.403 ENST00000525713.1
ENST00000374301.3
MTFR1L

mitochondrial fission regulator 1-like

chr1_+_3569072 1.399 ENST00000378295.4
ENST00000604074.1
TP73

tumor protein p73

chr1_+_179923873 1.393 ENST00000367607.3
ENST00000491495.2
CEP350

centrosomal protein 350kDa

chr2_-_20101385 1.392 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr10_+_124768482 1.388 ENST00000368869.4
ENST00000358776.4
ACADSB

acyl-CoA dehydrogenase, short/branched chain

chr17_+_53046096 1.361 ENST00000376352.2
ENST00000299341.4
ENST00000405898.1
ENST00000434978.2
ENST00000398391.2
STXBP4




syntaxin binding protein 4




chr15_+_66797627 1.356 ENST00000565627.1
ENST00000564179.1
ZWILCH

zwilch kinetochore protein

chr13_+_24734844 1.340 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr11_+_111848024 1.321 ENST00000315253.5
DIXDC1
DIX domain containing 1
chr6_+_18155632 1.302 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr17_-_4843206 1.288 ENST00000576951.1
SLC25A11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr7_-_75677251 1.267 ENST00000431581.1
ENST00000359697.3
ENST00000451157.1
ENST00000340062.5
ENST00000360591.3
ENST00000248600.1
STYXL1





serine/threonine/tyrosine interacting-like 1





chr7_-_150038704 1.244 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2



retinoic acid receptor responder (tazarotene induced) 2



chr2_-_43823119 1.228 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA



thyroid adenoma associated



chr1_+_110577229 1.220 ENST00000369795.3
ENST00000369794.2
STRIP1

striatin interacting protein 1

chr14_+_65381079 1.217 ENST00000549987.1
ENST00000542227.1
ENST00000447296.2
ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
CHURC1-FNTB
FNTB

CHURC1






CHURC1-FNTB readthrough
farnesyltransferase, CAAX box, beta

churchill domain containing 1






chr17_+_7590734 1.216 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr13_-_41768654 1.214 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr14_-_92413727 1.211 ENST00000267620.10
FBLN5
fibulin 5
chr6_-_146285455 1.210 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr3_+_42642106 1.202 ENST00000232978.8
NKTR
natural killer-tumor recognition sequence
chr4_+_48988259 1.196 ENST00000226432.4
CWH43
cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
chr4_+_186064395 1.194 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr1_+_111992064 1.192 ENST00000483994.1
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr15_+_44580899 1.191 ENST00000559222.1
ENST00000299957.6
CASC4

cancer susceptibility candidate 4

chr1_+_183441500 1.179 ENST00000456731.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chr5_+_75699040 1.178 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr15_-_73925651 1.176 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN


neuroplastin


chr16_+_57481349 1.162 ENST00000262507.6
ENST00000565964.1
COQ9

coenzyme Q9

chr20_+_30946106 1.159 ENST00000375687.4
ENST00000542461.1
ASXL1

additional sex combs like 1 (Drosophila)

chr5_+_75699149 1.156 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_+_149402553 1.151 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr15_+_66797455 1.143 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr1_-_223316611 1.143 ENST00000366881.1
TLR5
toll-like receptor 5
chr22_-_37172111 1.138 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27


intraflagellar transport 27 homolog (Chlamydomonas)


chr17_-_2415169 1.133 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
METTL16


methyltransferase like 16


chr8_+_81398444 1.132 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr4_-_168155730 1.128 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr22_-_37172191 1.117 ENST00000340630.5
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr5_+_56469843 1.114 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr21_-_34144157 1.110 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr16_-_54320675 1.107 ENST00000329734.3
IRX3
iroquois homeobox 3
chr6_-_146285221 1.089 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH


SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase


chr1_-_156252590 1.084 ENST00000361813.5
ENST00000368267.5
SMG5

SMG5 nonsense mediated mRNA decay factor

chr15_+_44580955 1.079 ENST00000345795.2
ENST00000360824.3
CASC4

cancer susceptibility candidate 4

chr1_+_28052456 1.078 ENST00000373954.6
ENST00000419687.2
FAM76A

family with sequence similarity 76, member A

chr22_-_23484246 1.074 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr8_-_144691718 1.071 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL


pyrroline-5-carboxylate reductase-like


chr5_-_127418755 1.068 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3




CTC-228N24.3




chr1_+_246887349 1.066 ENST00000366510.3
SCCPDH
saccharopine dehydrogenase (putative)
chr2_-_85555355 1.061 ENST00000282120.2
ENST00000398263.2
TGOLN2

trans-golgi network protein 2

chr1_-_47779762 1.059 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL



SCL/TAL1 interrupting locus



chr4_-_103748880 1.053 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr17_-_37607497 1.042 ENST00000394287.3
ENST00000300651.6
MED1

mediator complex subunit 1

chr3_+_169684553 1.040 ENST00000337002.4
ENST00000480708.1
SEC62

SEC62 homolog (S. cerevisiae)

chr9_-_136214877 1.033 ENST00000446777.1
ENST00000343730.5
ENST00000344469.5
ENST00000371999.1
ENST00000494177.2
ENST00000457204.2
MED22





mediator complex subunit 22





chr19_-_33555780 1.026 ENST00000254260.3
ENST00000400226.4
RHPN2

rhophilin, Rho GTPase binding protein 2

chr2_+_170683979 1.023 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr2_+_170683942 1.020 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr11_+_62104897 1.006 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1


asparaginase like 1


chr8_+_16884740 1.002 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr19_+_12273866 1.000 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136




zinc finger protein 136




chr6_+_18155560 0.994 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B


lysine (K)-specific demethylase 1B


chr7_-_128171123 0.993 ENST00000608477.1
RP11-212P7.2
RP11-212P7.2
chr10_-_127408011 0.991 ENST00000531977.1
ENST00000527483.1
ENST00000525909.1
ENST00000528844.1
ENST00000423178.2
RP11-383C5.4




RP11-383C5.4




chr7_+_99775366 0.989 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr6_-_107436473 0.986 ENST00000369042.1
BEND3
BEN domain containing 3
chrX_-_129402857 0.985 ENST00000447817.1
ENST00000370978.4
ZNF280C

zinc finger protein 280C

chr2_-_160761179 0.971 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
LY75


LY75-CD302

lymphocyte antigen 75


LY75-CD302 readthrough

chr5_+_138629337 0.968 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3


matrin 3


chr1_-_6614565 0.962 ENST00000377705.5
NOL9
nucleolar protein 9
chr2_-_10587897 0.961 ENST00000405333.1
ENST00000443218.1
ODC1

ornithine decarboxylase 1

chr19_+_35168567 0.948 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302





zinc finger protein 302





chr14_-_20923195 0.946 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr17_+_58755184 0.938 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr20_-_61569296 0.938 ENST00000370371.4
DIDO1
death inducer-obliterator 1
chr14_+_65007177 0.926 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chrX_-_80457385 0.923 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr12_-_29534074 0.918 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC2





ERGIC and golgi 2





chr3_+_49044798 0.911 ENST00000438660.1
ENST00000608424.1
ENST00000415265.2
WDR6


WD repeat domain 6


chr7_+_99775520 0.910 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr15_-_93616892 0.909 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA


repulsive guidance molecule family member a


chr17_-_4843316 0.899 ENST00000544061.2
SLC25A11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr13_-_22178284 0.896 ENST00000468222.2
ENST00000382374.4
MICU2

mitochondrial calcium uptake 2

chr11_+_94227129 0.895 ENST00000540349.1
ENST00000535502.1
ENST00000545130.1
ENST00000544253.1
ENST00000541144.1
ANKRD49




ankyrin repeat domain 49




chr4_-_178363581 0.879 ENST00000264595.2
AGA
aspartylglucosaminidase
chr1_+_104068562 0.879 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr18_-_59854203 0.864 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
PIGN









phosphatidylinositol glycan anchor biosynthesis, class N









chrX_+_40944871 0.861 ENST00000378308.2
ENST00000324545.8
USP9X

ubiquitin specific peptidase 9, X-linked

chr16_-_5147743 0.855 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A


family with sequence similarity 86, member A


chr13_+_21750780 0.849 ENST00000309594.4
MRP63
mitochondrial ribosomal protein 63
chr19_-_1876156 0.848 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr5_+_56469775 0.843 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr6_-_119399895 0.842 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr16_-_18468926 0.834 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr3_-_195270162 0.828 ENST00000438848.1
ENST00000328432.3
PPP1R2

protein phosphatase 1, regulatory (inhibitor) subunit 2

chr16_+_57769635 0.826 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1


katanin p80 (WD repeat containing) subunit B 1


chr18_-_53255766 0.823 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr3_-_125803105 0.821 ENST00000346785.5
ENST00000315891.6
SLC41A3

solute carrier family 41, member 3

chr3_+_93781728 0.820 ENST00000314622.4
NSUN3
NOP2/Sun domain family, member 3
chr14_-_64108125 0.815 ENST00000267522.3
WDR89
WD repeat domain 89
chr6_+_33168637 0.815 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr22_+_29279552 0.814 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr11_+_44087729 0.813 ENST00000524990.1
ENST00000263776.8
ACCS

1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)

chr22_-_21356375 0.802 ENST00000215742.4
ENST00000399133.2
THAP7

THAP domain containing 7

chr2_+_24714729 0.800 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr19_+_35168633 0.800 ENST00000505365.2
ZNF302
zinc finger protein 302
chr17_+_55162453 0.799 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1


A kinase (PRKA) anchor protein 1


chr7_+_99933730 0.796 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr1_+_41157671 0.795 ENST00000534399.1
ENST00000372653.1
NFYC

nuclear transcription factor Y, gamma

chr1_-_24306798 0.793 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10



serine/arginine-rich splicing factor 10



chr1_+_26147319 0.785 ENST00000374300.3
MTFR1L
mitochondrial fission regulator 1-like
chr1_-_70820357 0.777 ENST00000370944.4
ENST00000262346.6
ANKRD13C

ankyrin repeat domain 13C

chr12_-_22697343 0.774 ENST00000446597.1
ENST00000536386.1
ENST00000396028.2
ENST00000545552.1
ENST00000544930.1
ENST00000333957.4
C2CD5





C2 calcium-dependent domain containing 5





chr17_+_79935418 0.773 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr12_-_27091183 0.772 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN


asunder spermatogenesis regulator



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0032203 telomere formation via telomerase(GO:0032203)
1.5 6.0 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.1 14.8 GO:0006108 malate metabolic process(GO:0006108)
1.1 4.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.9 2.8 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.9 2.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.9 3.5 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.9 7.7 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.7 14.1 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.7 2.7 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6 0.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.6 1.7 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.5 2.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.4 2.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 2.4 GO:0015853 adenine transport(GO:0015853)
0.4 1.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.4 1.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.4 2.7 GO:1904526 regulation of microtubule binding(GO:1904526)
0.4 1.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.4 1.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.4 1.8 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.4 2.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.4 1.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 0.9 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 1.2 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.3 1.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.3 1.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.3 0.8 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.3 1.8 GO:0080009 mRNA methylation(GO:0080009)
0.3 2.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.3 1.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 1.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 0.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 1.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 1.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.7 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.9 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 0.6 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 0.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 10.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 4.1 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.2 GO:0018343 protein farnesylation(GO:0018343)
0.2 0.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 1.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 4.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.6 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.2 0.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 2.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.6 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.5 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 0.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.2 6.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 0.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.2 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 2.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.2 0.6 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.2 1.1 GO:0033504 floor plate development(GO:0033504)
0.1 1.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.4 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 2.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.8 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 7.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.6 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 1.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.4 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0048382 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382)
0.1 2.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 1.0 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.5 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.9 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.8 GO:0048478 replication fork protection(GO:0048478)
0.1 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:0035900 response to isolation stress(GO:0035900)
0.1 2.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 1.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.6 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 7.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.4 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 1.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 1.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.4 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 0.6 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.9 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.2 GO:0016573 histone acetylation(GO:0016573)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 3.5 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.6 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.9 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.8 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 2.8 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 1.0 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.8 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.6 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.7 GO:0032196 transposition(GO:0032196)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.6 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 2.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 2.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.3 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 12.7 GO:0030031 cell projection assembly(GO:0030031)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 2.4 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 1.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.0 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.2 GO:0021762 substantia nigra development(GO:0021762)
0.0 1.1 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.4 GO:0001525 angiogenesis(GO:0001525)
0.0 1.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0051665 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 1.1 GO:0032259 methylation(GO:0032259)
0.0 0.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.1 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0001534 radial spoke(GO:0001534)
1.0 7.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.9 7.7 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.6 2.5 GO:1990423 RZZ complex(GO:1990423)
0.5 2.0 GO:0032044 DSIF complex(GO:0032044)
0.4 11.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 1.1 GO:0034455 t-UTP complex(GO:0034455)
0.4 14.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.4 4.6 GO:0097433 dense body(GO:0097433)
0.3 1.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 6.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 1.6 GO:1990246 uniplex complex(GO:1990246)
0.3 1.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 2.0 GO:0061617 MICOS complex(GO:0061617)
0.2 0.7 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 2.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 2.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.9 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2 4.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 0.7 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.2 1.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 3.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.2 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0036128 CatSper complex(GO:0036128)
0.1 0.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.9 GO:0005827 polar microtubule(GO:0005827)
0.1 3.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 12.4 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 4.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.6 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 2.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.8 GO:0044754 autolysosome(GO:0044754)
0.1 0.8 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 11.6 GO:0031514 motile cilium(GO:0031514)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 4.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 2.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 2.4 GO:0016592 mediator complex(GO:0016592)
0.1 0.7 GO:0031298 replication fork protection complex(GO:0031298)
0.1 6.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.7 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 4.3 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439) ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 4.4 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 2.6 GO:0044450 microtubule organizing center part(GO:0044450)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 6.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 14.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.7 14.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.7 2.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.6 1.8 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.5 4.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 1.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.4 2.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.4 7.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.4 2.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.4 5.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 1.5 GO:0036033 mediator complex binding(GO:0036033)
0.3 13.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.3 1.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 0.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.3 1.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.3 1.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 0.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.7 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2 1.8 GO:0048039 ubiquinone binding(GO:0048039)
0.2 0.7 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 2.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 2.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 1.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 0.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 1.3 GO:0046979 TAP2 binding(GO:0046979)
0.2 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.9 GO:0031208 POZ domain binding(GO:0031208)
0.2 0.5 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.2 0.8 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.2 0.6 GO:0004803 transposase activity(GO:0004803)
0.2 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.6 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.0 GO:0050733 RS domain binding(GO:0050733)
0.1 0.4 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 4.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.7 GO:0000150 recombinase activity(GO:0000150)
0.1 1.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 1.2 GO:0015288 porin activity(GO:0015288)
0.1 0.6 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.6 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 7.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 6.0 GO:0042805 actinin binding(GO:0042805)
0.1 1.0 GO:0000182 rDNA binding(GO:0000182)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 1.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 2.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 0.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 2.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.4 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 1.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 3.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.7 GO:0034062 RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.5 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 3.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 1.2 PID_ALK2_PATHWAY ALK2 signaling events
0.1 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 1.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.9 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 3.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.3 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.6 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID_ATM_PATHWAY ATM pathway
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.1 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.0 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 10.0 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.8 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 2.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.1 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 0.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.9 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 2.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.4 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 2.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.4 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript