Motif ID: ZBTB33_CHD2
Z-value: 2.232
Transcription factors associated with ZBTB33_CHD2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
CHD2 | ENSG00000173575.14 | CHD2 |
ZBTB33 | ENSG00000177485.6 | ZBTB33 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
ZBTB33 | hg19_v2_chrX_+_119384607_119384720 | 0.69 | 1.9e-04 | Click! |
CHD2 | hg19_v2_chr15_+_93443419_93443580 | -0.53 | 7.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 10.7 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
1.5 | 6.0 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
1.1 | 14.8 | GO:0006108 | malate metabolic process(GO:0006108) |
1.1 | 4.2 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
0.9 | 2.8 | GO:0002023 | reduction of food intake in response to dietary excess(GO:0002023) |
0.9 | 2.7 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
0.9 | 3.5 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
0.9 | 7.7 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.7 | 14.1 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
0.7 | 2.7 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.6 | 0.6 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.6 | 1.7 | GO:1901297 | positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
0.5 | 2.0 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168) |
0.4 | 2.0 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.4 | 2.4 | GO:0015853 | adenine transport(GO:0015853) |
0.4 | 1.2 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
0.4 | 1.2 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.4 | 2.7 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
0.4 | 1.1 | GO:0034146 | toll-like receptor 5 signaling pathway(GO:0034146) |
0.4 | 1.1 | GO:1990180 | mitochondrial tRNA 3'-end processing(GO:1990180) |
0.4 | 1.8 | GO:0002154 | thyroid hormone mediated signaling pathway(GO:0002154) |
0.4 | 2.2 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
0.4 | 1.8 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.3 | 0.9 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.3 | 1.2 | GO:0072134 | nephrogenic mesenchyme morphogenesis(GO:0072134) |
0.3 | 1.2 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
0.3 | 1.1 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
0.3 | 0.8 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
0.3 | 1.8 | GO:0080009 | mRNA methylation(GO:0080009) |
0.3 | 2.3 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.3 | 1.0 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
0.2 | 1.2 | GO:0061760 | antifungal innate immune response(GO:0061760) |
0.2 | 0.5 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
0.2 | 1.0 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
0.2 | 1.7 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.2 | 0.7 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
0.2 | 0.7 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
0.2 | 0.9 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
0.2 | 0.6 | GO:0019521 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
0.2 | 0.8 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.2 | 10.5 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.2 | 4.1 | GO:0070986 | left/right axis specification(GO:0070986) |
0.2 | 1.2 | GO:0018343 | protein farnesylation(GO:0018343) |
0.2 | 0.6 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.2 | 1.0 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.2 | 4.7 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
0.2 | 0.6 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
0.2 | 0.8 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.2 | 2.8 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.2 | 0.6 | GO:0071139 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
0.2 | 0.7 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
0.2 | 0.5 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.2 | 0.9 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
0.2 | 6.3 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.2 | 0.5 | GO:0045360 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) |
0.2 | 0.5 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
0.2 | 0.8 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.2 | 2.2 | GO:0003356 | regulation of cilium beat frequency(GO:0003356) |
0.2 | 0.6 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
0.2 | 1.1 | GO:0033504 | floor plate development(GO:0033504) |
0.1 | 1.2 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
0.1 | 1.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 0.4 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
0.1 | 0.6 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.1 | 0.6 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
0.1 | 2.8 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.1 | 1.4 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
0.1 | 0.3 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
0.1 | 0.8 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.1 | 1.8 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
0.1 | 7.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.1 | 2.0 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.1 | 0.6 | GO:1902741 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
0.1 | 1.7 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
0.1 | 0.2 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.1 | 0.6 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
0.1 | 0.4 | GO:0009443 | pyridoxal 5'-phosphate salvage(GO:0009443) |
0.1 | 0.8 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.1 | 0.7 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 0.5 | GO:0048382 | lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382) |
0.1 | 2.7 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.1 | 0.3 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
0.1 | 0.7 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.1 | 0.4 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.1 | 1.0 | GO:0006528 | asparagine metabolic process(GO:0006528) |
0.1 | 0.5 | GO:0031392 | regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) |
0.1 | 0.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.1 | 0.9 | GO:0006552 | leucine catabolic process(GO:0006552) |
0.1 | 0.8 | GO:0048478 | replication fork protection(GO:0048478) |
0.1 | 0.6 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.1 | 0.2 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
0.1 | 1.2 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.1 | 0.7 | GO:0035900 | response to isolation stress(GO:0035900) |
0.1 | 2.3 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
0.1 | 0.3 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.1 | 0.3 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
0.1 | 1.3 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
0.1 | 0.8 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.1 | 1.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.1 | 0.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.4 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.1 | 0.7 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.1 | 0.4 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
0.1 | 0.5 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
0.1 | 0.5 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.1 | 0.6 | GO:0048105 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
0.1 | 1.0 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
0.1 | 7.3 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
0.1 | 0.3 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.1 | 0.8 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.1 | 0.4 | GO:0072396 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
0.1 | 0.2 | GO:0060931 | sinoatrial node cell development(GO:0060931) |
0.1 | 1.9 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.1 | 0.3 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
0.1 | 1.1 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 1.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.2 | GO:2000870 | regulation of progesterone secretion(GO:2000870) |
0.1 | 0.4 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.1 | 0.6 | GO:0009414 | response to water deprivation(GO:0009414) |
0.1 | 0.2 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
0.1 | 1.4 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.1 | 0.9 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
0.1 | 0.2 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
0.1 | 0.4 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.1 | 1.2 | GO:0016573 | histone acetylation(GO:0016573) |
0.1 | 0.8 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.8 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.0 | 0.5 | GO:0006768 | biotin metabolic process(GO:0006768) |
0.0 | 0.3 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
0.0 | 3.5 | GO:0021795 | cerebral cortex cell migration(GO:0021795) |
0.0 | 0.6 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
0.0 | 0.2 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
0.0 | 0.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.9 | GO:0006517 | protein deglycosylation(GO:0006517) |
0.0 | 1.4 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.1 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
0.0 | 0.8 | GO:0007599 | blood coagulation(GO:0007596) hemostasis(GO:0007599) |
0.0 | 0.7 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
0.0 | 0.2 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
0.0 | 0.1 | GO:0071335 | submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
0.0 | 0.9 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.0 | 2.8 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.2 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
0.0 | 1.0 | GO:0071467 | cellular response to pH(GO:0071467) |
0.0 | 0.2 | GO:0010446 | response to alkaline pH(GO:0010446) |
0.0 | 0.3 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
0.0 | 0.6 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
0.0 | 0.4 | GO:0010265 | SCF complex assembly(GO:0010265) |
0.0 | 1.5 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.2 | GO:0072313 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
0.0 | 0.8 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.0 | 0.3 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.0 | 1.6 | GO:0006505 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.2 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
0.0 | 0.6 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
0.0 | 0.7 | GO:0032196 | transposition(GO:0032196) |
0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.1 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
0.0 | 0.2 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
0.0 | 0.5 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 1.9 | GO:0035082 | axoneme assembly(GO:0035082) |
0.0 | 1.0 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
0.0 | 0.6 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
0.0 | 0.3 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.0 | 2.8 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.0 | 0.2 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
0.0 | 0.2 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 2.0 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
0.0 | 0.3 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.0 | 0.1 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
0.0 | 0.3 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.0 | 0.8 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
0.0 | 0.1 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.0 | 12.7 | GO:0030031 | cell projection assembly(GO:0030031) |
0.0 | 0.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.1 | GO:0010767 | regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) |
0.0 | 0.1 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676) |
0.0 | 0.7 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.1 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.0 | 0.1 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.0 | 0.4 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
0.0 | 0.2 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.0 | 0.3 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
0.0 | 0.1 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
0.0 | 2.4 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
0.0 | 0.1 | GO:0015846 | polyamine transport(GO:0015846) |
0.0 | 0.8 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.0 | 0.6 | GO:0007098 | centrosome cycle(GO:0007098) |
0.0 | 0.1 | GO:0015917 | aminophospholipid transport(GO:0015917) |
0.0 | 0.3 | GO:0097264 | self proteolysis(GO:0097264) |
0.0 | 0.1 | GO:0035283 | rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
0.0 | 0.1 | GO:0001927 | exocyst assembly(GO:0001927) |
0.0 | 1.3 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
0.0 | 0.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.0 | 0.1 | GO:1904808 | regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808) |
0.0 | 0.0 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.5 | GO:0009303 | rRNA transcription(GO:0009303) |
0.0 | 0.2 | GO:0048255 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
0.0 | 0.5 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.8 | GO:0007140 | male meiosis(GO:0007140) |
0.0 | 0.1 | GO:0034088 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
0.0 | 0.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
0.0 | 0.4 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.0 | 0.2 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 1.2 | GO:0021762 | substantia nigra development(GO:0021762) |
0.0 | 1.1 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 0.5 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.0 | 0.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.2 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 0.1 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.0 | 1.1 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
0.0 | 0.1 | GO:1901804 | beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) |
0.0 | 0.1 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
0.0 | 0.1 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
0.0 | 0.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.4 | GO:0001525 | angiogenesis(GO:0001525) |
0.0 | 1.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.2 | GO:0051665 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665) |
0.0 | 0.1 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.4 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.3 | GO:0015671 | oxygen transport(GO:0015671) |
0.0 | 1.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.0 | 0.4 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
0.0 | 0.2 | GO:0032288 | myelin assembly(GO:0032288) |
0.0 | 0.1 | GO:1902659 | regulation of glucose mediated signaling pathway(GO:1902659) |
0.0 | 1.1 | GO:0032259 | methylation(GO:0032259) |
0.0 | 0.5 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
0.0 | 0.4 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.3 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.1 | GO:0042713 | sperm ejaculation(GO:0042713) |
0.0 | 0.0 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.0 | 0.1 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.0 | 0.2 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.1 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
0.0 | 0.6 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 1.1 | GO:0002576 | platelet degranulation(GO:0002576) |
0.0 | 1.2 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
0.0 | 0.1 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
0.0 | 0.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:0001771 | immunological synapse formation(GO:0001771) |
0.0 | 0.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.1 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.2 | GO:0001534 | radial spoke(GO:0001534) |
1.0 | 7.3 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
0.9 | 7.7 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
0.6 | 2.5 | GO:1990423 | RZZ complex(GO:1990423) |
0.5 | 2.0 | GO:0032044 | DSIF complex(GO:0032044) |
0.4 | 11.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.4 | 1.1 | GO:0034455 | t-UTP complex(GO:0034455) |
0.4 | 14.2 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.4 | 4.6 | GO:0097433 | dense body(GO:0097433) |
0.3 | 1.7 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.3 | 6.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.3 | 1.6 | GO:1990246 | uniplex complex(GO:1990246) |
0.3 | 1.2 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.2 | 2.0 | GO:0061617 | MICOS complex(GO:0061617) |
0.2 | 0.7 | GO:1990716 | axonemal central apparatus(GO:1990716) |
0.2 | 2.1 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.2 | 2.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.2 | 0.9 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
0.2 | 4.4 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.2 | 0.7 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
0.2 | 0.2 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.2 | 1.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.2 | 0.7 | GO:0060187 | cell pole(GO:0060187) |
0.2 | 0.6 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.1 | 0.4 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
0.1 | 3.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.1 | 0.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 0.9 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.1 | 1.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 1.2 | GO:0071953 | elastic fiber(GO:0071953) |
0.1 | 0.9 | GO:0036128 | CatSper complex(GO:0036128) |
0.1 | 0.7 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.1 | 0.9 | GO:0005827 | polar microtubule(GO:0005827) |
0.1 | 3.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.1 | 0.7 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 0.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 12.4 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
0.1 | 4.1 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 0.8 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.1 | 0.6 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.1 | 2.4 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.1 | 0.5 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.1 | 0.8 | GO:0044754 | autolysosome(GO:0044754) |
0.1 | 0.8 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
0.1 | 11.6 | GO:0031514 | motile cilium(GO:0031514) |
0.1 | 0.3 | GO:0031213 | RSF complex(GO:0031213) |
0.1 | 4.8 | GO:0000786 | nucleosome(GO:0000786) |
0.1 | 0.3 | GO:0070081 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
0.1 | 1.6 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
0.1 | 2.5 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 1.2 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
0.1 | 1.2 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 0.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.1 | 0.4 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.1 | 2.4 | GO:0016592 | mediator complex(GO:0016592) |
0.1 | 0.7 | GO:0031298 | replication fork protection complex(GO:0031298) |
0.1 | 6.2 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.3 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
0.0 | 0.3 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
0.0 | 0.3 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.0 | 1.9 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 0.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.5 | GO:0070652 | HAUS complex(GO:0070652) |
0.0 | 0.4 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
0.0 | 0.3 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.0 | 0.1 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 0.8 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 0.7 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.0 | 4.3 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.3 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.0 | 0.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 0.1 | GO:0035061 | interchromatin granule(GO:0035061) |
0.0 | 0.1 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
0.0 | 0.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 0.8 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) ciliary transition fiber(GO:0097539) |
0.0 | 0.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.0 | 0.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.0 | 4.4 | GO:0035770 | ribonucleoprotein granule(GO:0035770) |
0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 1.9 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.1 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.0 | 1.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 2.6 | GO:0044450 | microtubule organizing center part(GO:0044450) |
0.0 | 0.9 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 1.6 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.0 | 0.3 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 1.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 1.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.1 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
0.0 | 6.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 1.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 0.2 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 0.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.2 | GO:0043034 | costamere(GO:0043034) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 14.8 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
1.7 | 14.9 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.7 | 2.1 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
0.6 | 1.8 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
0.5 | 4.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.5 | 1.5 | GO:0030626 | U12 snRNA binding(GO:0030626) |
0.4 | 2.2 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
0.4 | 7.1 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.4 | 2.3 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
0.4 | 5.7 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.4 | 1.5 | GO:0036033 | mediator complex binding(GO:0036033) |
0.3 | 13.6 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.3 | 1.0 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
0.3 | 0.9 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.3 | 1.2 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.3 | 1.2 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
0.3 | 1.2 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.3 | 0.9 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.2 | 0.7 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
0.2 | 1.8 | GO:0048039 | ubiquinone binding(GO:0048039) |
0.2 | 0.7 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
0.2 | 2.8 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.2 | 2.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.2 | 1.2 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.2 | 0.6 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
0.2 | 1.0 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
0.2 | 0.9 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
0.2 | 0.5 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
0.2 | 1.3 | GO:0046979 | TAP2 binding(GO:0046979) |
0.2 | 0.5 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
0.2 | 0.9 | GO:0031208 | POZ domain binding(GO:0031208) |
0.2 | 0.5 | GO:0004324 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
0.2 | 0.8 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
0.2 | 0.6 | GO:0004803 | transposase activity(GO:0004803) |
0.2 | 0.5 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.2 | 0.6 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
0.2 | 0.6 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.1 | 0.6 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
0.1 | 1.0 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 0.4 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
0.1 | 0.6 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.1 | 4.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 1.7 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 1.1 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.1 | 0.5 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.1 | 1.2 | GO:0015288 | porin activity(GO:0015288) |
0.1 | 0.6 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
0.1 | 0.4 | GO:0008478 | pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403) |
0.1 | 0.3 | GO:0090541 | MIT domain binding(GO:0090541) |
0.1 | 0.7 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.1 | 0.5 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.1 | 0.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.7 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
0.1 | 0.3 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
0.1 | 0.3 | GO:0030627 | pre-mRNA 5'-splice site binding(GO:0030627) |
0.1 | 1.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 0.4 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.1 | 0.6 | GO:0005072 | transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) |
0.1 | 7.9 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.1 | 2.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 3.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.1 | 6.0 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 1.0 | GO:0000182 | rDNA binding(GO:0000182) |
0.1 | 0.8 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.1 | 0.5 | GO:0004522 | ribonuclease A activity(GO:0004522) |
0.1 | 0.5 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.1 | 0.2 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
0.1 | 1.4 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.1 | 0.1 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.1 | 0.2 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
0.1 | 0.6 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.1 | 1.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.1 | 0.4 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.1 | 2.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 0.7 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731) |
0.1 | 0.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.1 | 1.6 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.1 | 0.7 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.1 | 2.2 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
0.1 | 0.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.1 | 0.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.1 | 1.6 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
0.1 | 2.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 0.9 | GO:1990459 | transferrin receptor binding(GO:1990459) |
0.1 | 0.2 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
0.1 | 0.6 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.1 | 0.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.1 | 0.8 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 0.2 | GO:0016212 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
0.1 | 0.2 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
0.1 | 0.6 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.1 | 0.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.0 | 0.6 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.0 | 0.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 1.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.2 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.0 | 0.3 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.0 | 0.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.0 | 0.4 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
0.0 | 1.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.3 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 1.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.1 | GO:0045145 | single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145) |
0.0 | 1.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 1.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 1.7 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
0.0 | 0.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.1 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
0.0 | 0.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.0 | 0.1 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
0.0 | 0.9 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 1.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.0 | 0.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 0.2 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
0.0 | 3.9 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.8 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.0 | 1.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.3 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
0.0 | 0.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.0 | 0.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.6 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 1.7 | GO:0034062 | RNA polymerase activity(GO:0034062) |
0.0 | 0.1 | GO:0032427 | GBD domain binding(GO:0032427) |
0.0 | 0.4 | GO:0010181 | FMN binding(GO:0010181) |
0.0 | 0.4 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.0 | 0.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.2 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
0.0 | 0.1 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 0.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 2.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 2.2 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 1.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.1 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.0 | 0.1 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.0 | 0.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.3 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.0 | 0.1 | GO:1903136 | cuprous ion binding(GO:1903136) |
0.0 | 0.5 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.4 | GO:0034979 | NAD-dependent protein deacetylase activity(GO:0034979) |
0.0 | 0.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.3 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 1.1 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.4 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.3 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.7 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 1.3 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 3.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.1 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.4 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.1 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.0 | 0.2 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.0 | 0.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 1.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.1 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.0 | 1.4 | GO:0019905 | syntaxin binding(GO:0019905) |
0.0 | 2.5 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.2 | GO:0008494 | translation activator activity(GO:0008494) |
0.0 | 0.6 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 3.8 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.0 | 0.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.0 | 0.3 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.0 | 0.8 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 2.5 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.0 | 0.2 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 1.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.8 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.8 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.1 | 1.2 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 0.5 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.1 | 1.6 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 1.1 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 2.7 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.8 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 1.4 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.0 | 1.1 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.9 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 1.6 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.9 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
0.0 | 0.9 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 1.4 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 1.2 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 0.2 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.0 | 3.8 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.3 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 0.6 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 0.2 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.0 | 0.3 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.7 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.4 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.2 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.4 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 0.3 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 0.1 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.0 | 0.3 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.5 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.0 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.5 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.4 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 5.9 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.3 | 10.0 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.1 | 1.4 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.1 | 1.7 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.1 | 1.8 | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
0.1 | 2.3 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.1 | 2.1 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
0.1 | 0.4 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.1 | 1.8 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.1 | 1.5 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 1.9 | REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
0.1 | 1.3 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.0 | 0.6 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.0 | 0.7 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 1.1 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 1.0 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.4 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.0 | 1.4 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 1.1 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.0 | 2.2 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.6 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.9 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.9 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 1.4 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
0.0 | 0.1 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
0.0 | 2.4 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.6 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.5 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 0.6 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
0.0 | 0.3 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 1.4 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.3 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.3 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.0 | 0.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 0.8 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
0.0 | 0.5 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 1.0 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.2 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.4 | REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION | Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
0.0 | 0.4 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 0.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.2 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.9 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.1 | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |