Motif ID: UGCAUAG

Z-value: 0.708


Mature miRNA associated with seed UGCAUAG:

NamemiRBase Accession
hsa-miR-153-3p MIMAT0000439



Activity profile for motif UGCAUAG.

activity profile for motif UGCAUAG


Sorted Z-values histogram for motif UGCAUAG

Sorted Z-values for motif UGCAUAG



Network of associatons between targets according to the STRING database.



First level regulatory network of UGCAUAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_149365827 2.845 ENST00000344721.4
 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr1_+_228870824 1.896 ENST00000366691.3
 RHOU
ras homolog family member U
chr4_-_23891693 1.601 ENST00000264867.2
 PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_+_140254884 1.594 ENST00000398631.2
 PCDHA12
protocadherin alpha 12
chr5_+_140227048 1.589 ENST00000532602.1
 PCDHA9
protocadherin alpha 9
chr5_+_140248518 1.564 ENST00000398640.2
 PCDHA11
protocadherin alpha 11
chr5_+_140213815 1.535 ENST00000525929.1
ENST00000378125.3
 PCDHA7

protocadherin alpha 7

chr5_+_140220769 1.485 ENST00000531613.1
ENST00000378123.3
 PCDHA8

protocadherin alpha 8

chr17_+_55333876 1.345 ENST00000284073.2
 MSI2
musashi RNA-binding protein 2
chr2_+_121103706 1.246 ENST00000295228.3
 INHBB
inhibin, beta B
chr5_+_156693091 1.142 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
 CYFIP2



cytoplasmic FMR1 interacting protein 2



chr9_-_125693757 1.086 ENST00000373656.3
 ZBTB26
zinc finger and BTB domain containing 26
chr3_+_69812877 1.084 ENST00000457080.1
ENST00000328528.6
 MITF

microphthalmia-associated transcription factor

chr7_+_89841000 1.076 ENST00000287908.3
 STEAP2
STEAP family member 2, metalloreductase
chr15_+_75287861 1.052 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
 SCAMP5







secretory carrier membrane protein 5







chr2_-_202316260 1.027 ENST00000332624.3
 TRAK2
trafficking protein, kinesin binding 2
chr1_+_61547894 1.010 ENST00000403491.3
 NFIA
nuclear factor I/A
chr10_+_25463951 1.006 ENST00000376351.3
 GPR158
G protein-coupled receptor 158
chr12_+_93771659 0.999 ENST00000337179.5
ENST00000415493.2
 NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4

chr6_+_135502466 0.960 ENST00000367814.4
 MYB
v-myb avian myeloblastosis viral oncogene homolog

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 129 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.5 1.6 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.3 1.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.0 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 1.0 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.9 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.9 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.9 GO:0032648 regulation of interferon-beta production(GO:0032648)
0.0 0.8 GO:0044320 cellular response to leptin stimulus(GO:0044320)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0097440 apical dendrite(GO:0097440)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.5 GO:0002102 podosome(GO:0002102)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 0.5 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 1.0 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in C2:CP category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.5 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG