Motif ID: UCCAGUU

Z-value: 0.405


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145-5p MIMAT0000437
hsa-miR-5195-3p MIMAT0021127



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151561085 1.247 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr7_+_5632436 1.171 ENST00000340250.6
ENST00000382361.3
FSCN1

fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

chr7_+_100770328 1.107 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr17_+_70117153 0.954 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr12_+_4382917 0.875 ENST00000261254.3
CCND2
cyclin D2
chr11_-_119599794 0.690 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr7_-_83824169 0.593 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_125348448 0.584 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr7_+_130126012 0.551 ENST00000341441.5
MEST
mesoderm specific transcript
chr15_-_52821247 0.540 ENST00000399231.3
ENST00000399233.2
MYO5A

myosin VA (heavy chain 12, myoxin)

chr8_+_26435359 0.452 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr5_-_157002775 0.451 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr12_-_124018252 0.442 ENST00000376874.4
RILPL1
Rab interacting lysosomal protein-like 1
chr15_+_52121822 0.413 ENST00000558455.1
ENST00000308580.7
TMOD3

tropomodulin 3 (ubiquitous)

chr10_-_74856608 0.399 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1





prolyl 4-hydroxylase, alpha polypeptide I





chr3_+_47324424 0.393 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr15_+_67358163 0.388 ENST00000327367.4
SMAD3
SMAD family member 3
chr2_+_9346892 0.374 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr15_-_34628951 0.372 ENST00000397707.2
ENST00000560611.1
SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr19_+_16187085 0.371 ENST00000300933.4
TPM4
tropomyosin 4
chr20_-_25566153 0.370 ENST00000278886.6
ENST00000422516.1
NINL

ninein-like

chr1_-_67519782 0.357 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr14_-_35182994 0.355 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr6_+_41606176 0.349 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI




MyoD family inhibitor




chr21_+_40177143 0.345 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr1_-_208417620 0.331 ENST00000367033.3
PLXNA2
plexin A2
chr2_-_96781984 0.329 ENST00000409345.3
ADRA2B
adrenoceptor alpha 2B
chr5_+_86564739 0.321 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1


RAS p21 protein activator (GTPase activating protein) 1


chr22_+_38035459 0.317 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr16_+_4421841 0.313 ENST00000304735.3
VASN
vasorin
chr10_+_5454505 0.309 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr5_-_77844974 0.306 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr22_+_21271714 0.285 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr9_-_35732362 0.275 ENST00000314888.9
ENST00000540444.1
TLN1

talin 1

chr2_-_74667612 0.274 ENST00000305557.5
ENST00000233330.6
RTKN

rhotekin

chr10_+_112404132 0.270 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr1_+_86046433 0.269 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr7_+_77166592 0.266 ENST00000248594.6
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr16_-_4987065 0.260 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chr6_-_88411911 0.258 ENST00000257787.5
AKIRIN2
akirin 2
chr19_+_39616410 0.252 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr7_-_92463210 0.249 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr9_-_110251836 0.247 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr5_+_14143728 0.246 ENST00000344204.4
ENST00000537187.1
TRIO

trio Rho guanine nucleotide exchange factor

chr12_+_49761224 0.241 ENST00000553127.1
ENST00000321898.6
SPATS2

spermatogenesis associated, serine-rich 2

chr14_+_50359773 0.239 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr11_-_118134997 0.238 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr16_+_16043406 0.237 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1





ATP-binding cassette, sub-family C (CFTR/MRP), member 1





chr2_-_106810783 0.237 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr4_-_80994210 0.234 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr16_-_79634595 0.233 ENST00000326043.4
ENST00000393350.1
MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chr9_+_128509624 0.231 ENST00000342287.5
ENST00000373487.4
PBX3

pre-B-cell leukemia homeobox 3

chr10_+_18948311 0.230 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr2_+_203879568 0.229 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr6_+_106546808 0.225 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr8_-_23712312 0.223 ENST00000290271.2
STC1
stanniocalcin 1
chr12_-_120687948 0.221 ENST00000458477.2
PXN
paxillin
chr13_+_52158610 0.211 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr22_-_18507279 0.207 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
MICAL3



microtubule associated monooxygenase, calponin and LIM domain containing 3



chr3_+_57994127 0.205 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
FLNB





filamin B, beta





chr15_-_63674218 0.205 ENST00000178638.3
CA12
carbonic anhydrase XII
chr1_+_206557366 0.202 ENST00000414007.1
ENST00000419187.2
SRGAP2

SLIT-ROBO Rho GTPase activating protein 2

chr11_-_128392085 0.202 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr1_-_54199877 0.200 ENST00000312233.2
GLIS1
GLIS family zinc finger 1
chr2_+_228336849 0.200 ENST00000409979.2
ENST00000310078.8
AGFG1

ArfGAP with FG repeats 1

chr1_+_28696111 0.194 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr5_+_174905398 0.194 ENST00000321442.5
SFXN1
sideroflexin 1
chr14_-_45431091 0.194 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28


kelch-like family member 28


chr1_-_38325256 0.193 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr12_-_93323013 0.190 ENST00000322349.8
EEA1
early endosome antigen 1
chr8_-_125384927 0.189 ENST00000297632.6
TMEM65
transmembrane protein 65
chr7_-_27183263 0.189 ENST00000222726.3
HOXA5
homeobox A5
chr10_+_96162242 0.189 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr8_-_28243934 0.187 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chr5_+_115177178 0.187 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr3_+_111578027 0.186 ENST00000431670.2
ENST00000412622.1
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr7_-_23053693 0.184 ENST00000409763.1
ENST00000409923.1
FAM126A

family with sequence similarity 126, member A

chr6_-_99797522 0.182 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr5_-_111754948 0.181 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr1_-_159893507 0.178 ENST00000368096.1
TAGLN2
transgelin 2
chr19_-_11308190 0.169 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr8_-_42751820 0.166 ENST00000526349.1
ENST00000527424.1
ENST00000534961.1
ENST00000319073.4
RNF170



ring finger protein 170



chr11_+_111473108 0.164 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr11_+_76494253 0.164 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr16_-_23160591 0.163 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr3_+_98451275 0.161 ENST00000265261.6
ENST00000497008.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr16_-_85722530 0.157 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr17_+_36508111 0.157 ENST00000331159.5
ENST00000577233.1
SOCS7

suppressor of cytokine signaling 7

chr6_-_693074 0.155 ENST00000230449.4
ENST00000443083.1
ENST00000448181.3
EXOC2


exocyst complex component 2


chr1_-_115259337 0.154 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr14_-_20020272 0.154 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr14_+_19553365 0.152 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr11_+_86748863 0.151 ENST00000340353.7
TMEM135
transmembrane protein 135
chr14_-_50698276 0.150 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr2_+_79740118 0.148 ENST00000496558.1
ENST00000451966.1
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr3_-_189838670 0.146 ENST00000319332.5
LEPREL1
leprecan-like 1
chr18_-_51751132 0.145 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr6_+_117586713 0.144 ENST00000352536.3
ENST00000326274.5
VGLL2

vestigial like 2 (Drosophila)

chr12_-_95611149 0.142 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6


FYVE, RhoGEF and PH domain containing 6


chr1_+_52682052 0.141 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr8_-_66754172 0.141 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chrX_+_48916497 0.140 ENST00000496529.2
ENST00000376396.3
ENST00000422185.2
ENST00000603986.1
ENST00000536628.2
CCDC120




coiled-coil domain containing 120




chrX_+_48432892 0.140 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr1_-_211307315 0.139 ENST00000271751.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr4_-_78740511 0.136 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L


CCR4-NOT transcription complex, subunit 6-like


chr9_-_95432536 0.136 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr12_-_95044309 0.135 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr8_-_18871159 0.134 ENST00000327040.8
ENST00000440756.2
PSD3

pleckstrin and Sec7 domain containing 3

chr7_+_135347215 0.133 ENST00000507606.1
C7orf73
chromosome 7 open reading frame 73
chr10_+_17686124 0.133 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr19_-_40324255 0.133 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr2_-_204400113 0.132 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_+_178062855 0.132 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr10_-_25012597 0.132 ENST00000396432.2
ARHGAP21
Rho GTPase activating protein 21
chr1_-_70671216 0.130 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr17_-_40306934 0.127 ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
ENST00000592574.1
RAB5C



CTD-2132N18.3
RAB5C, member RAS oncogene family



Uncharacterized protein
chr4_-_114682936 0.125 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D




calcium/calmodulin-dependent protein kinase II delta




chr3_-_9291063 0.125 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr2_+_204571198 0.123 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28


CD28 molecule


chr3_+_57261743 0.123 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr5_+_78908233 0.122 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAPD4



PAP associated domain containing 4



chr2_-_227664474 0.122 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr22_-_46933067 0.122 ENST00000262738.3
ENST00000395964.1
CELSR1

cadherin, EGF LAG seven-pass G-type receptor 1

chr19_+_56165480 0.121 ENST00000450554.2
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr1_+_200708671 0.118 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr10_+_112631547 0.114 ENST00000280154.7
ENST00000393104.2
PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chr8_-_27630102 0.114 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
CCDC25


coiled-coil domain containing 25


chr4_+_78078304 0.113 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr14_+_67707826 0.113 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr12_+_53774423 0.113 ENST00000426431.2
SP1
Sp1 transcription factor
chr4_-_68566832 0.112 ENST00000420827.2
ENST00000322244.5
UBA6

ubiquitin-like modifier activating enzyme 6

chr7_+_116139424 0.112 ENST00000222693.4
CAV2
caveolin 2
chr6_-_11232891 0.110 ENST00000379433.5
ENST00000379446.5
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr2_-_9695847 0.110 ENST00000310823.3
ENST00000497134.1
ADAM17

ADAM metallopeptidase domain 17

chr13_-_99630233 0.109 ENST00000376460.1
ENST00000442173.1
DOCK9

dedicator of cytokinesis 9

chr2_+_26568965 0.109 ENST00000260585.7
ENST00000447170.1
EPT1

ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

chr9_+_78505581 0.109 ENST00000376767.3
ENST00000376752.4
PCSK5

proprotein convertase subtilisin/kexin type 5

chr1_-_94703118 0.108 ENST00000260526.6
ENST00000370217.3
ARHGAP29

Rho GTPase activating protein 29

chr15_+_41523335 0.108 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr6_+_71122974 0.107 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr1_+_50574585 0.106 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr9_+_112403088 0.106 ENST00000448454.2
PALM2
paralemmin 2
chr5_+_151151471 0.105 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr3_+_9404526 0.104 ENST00000452837.2
ENST00000417036.1
ENST00000419437.1
ENST00000345094.3
ENST00000515662.2
THUMPD3




THUMP domain containing 3




chr12_+_96588143 0.104 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr7_+_20370746 0.102 ENST00000222573.4
ITGB8
integrin, beta 8
chr1_-_183604794 0.102 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5


actin related protein 2/3 complex, subunit 5, 16kDa


chr2_-_129076151 0.101 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr1_+_40420802 0.100 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A



major facilitator superfamily domain containing 2A



chr1_+_39456895 0.100 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr5_+_167181917 0.100 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr11_+_128563652 0.099 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_32914579 0.099 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr10_-_102046098 0.099 ENST00000441611.1
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chr19_+_56186557 0.099 ENST00000270460.6
EPN1
epsin 1
chr3_+_141205852 0.097 ENST00000286364.3
ENST00000452898.1
RASA2

RAS p21 protein activator 2

chr2_-_131267239 0.097 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr18_-_18691739 0.097 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr15_+_72766651 0.095 ENST00000379887.4
ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
chr3_+_110790590 0.094 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr3_+_171758344 0.094 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr2_-_216300784 0.093 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr9_-_107690420 0.092 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr9_+_80912059 0.092 ENST00000347159.2
ENST00000376588.3
PSAT1

phosphoserine aminotransferase 1

chr5_+_135468516 0.091 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5



SMAD family member 5



chr1_-_1822495 0.088 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr18_+_3247413 0.088 ENST00000579226.1
ENST00000217652.3
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr2_+_153191706 0.087 ENST00000288670.9
FMNL2
formin-like 2
chr1_+_167691191 0.087 ENST00000392121.3
ENST00000474859.1
MPZL1

myelin protein zero-like 1

chr3_-_195808952 0.086 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC



transferrin receptor



chr17_+_74261277 0.086 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr6_+_7107999 0.085 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1


ras responsive element binding protein 1


chr7_+_129710350 0.085 ENST00000335420.5
ENST00000463413.1
KLHDC10

kelch domain containing 10

chr19_-_2456922 0.084 ENST00000582871.1
ENST00000325327.3
LMNB2

lamin B2

chr3_+_101504200 0.083 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr13_+_80055284 0.083 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr15_+_45879321 0.081 ENST00000220531.3
ENST00000567461.1
BLOC1S6

biogenesis of lysosomal organelles complex-1, subunit 6, pallidin

chr10_-_60027642 0.081 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr3_-_113465065 0.081 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr3_-_142166904 0.081 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr20_-_46415297 0.079 ENST00000467815.1
ENST00000359930.4
SULF2

sulfatase 2

chr11_-_118966167 0.078 ENST00000530167.1
H2AFX
H2A histone family, member X
chr20_+_1875110 0.078 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr11_+_33278811 0.078 ENST00000303296.4
ENST00000379016.3
HIPK3

homeodomain interacting protein kinase 3

chr11_-_33183006 0.076 ENST00000524827.1
ENST00000323959.4
ENST00000431742.2
CSTF3


cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa


chr7_-_5570229 0.076 ENST00000331789.5
ACTB
actin, beta
chr11_+_64794875 0.075 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
SNX15


sorting nexin 15


chr1_-_154155595 0.073 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
TPM3




tropomyosin 3




chr17_-_62207485 0.073 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1
chr17_+_18218587 0.072 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr1_+_155051305 0.072 ENST00000368408.3
EFNA3
ephrin-A3
chr6_+_147830063 0.071 ENST00000367474.1
SAMD5
sterile alpha motif domain containing 5
chr20_+_61427797 0.071 ENST00000370487.3
MRGBP
MRG/MORF4L binding protein
chrX_-_11445856 0.070 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr7_+_30323923 0.070 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr1_-_171711387 0.070 ENST00000236192.7
VAMP4
vesicle-associated membrane protein 4
chr5_+_60628074 0.070 ENST00000252744.5
ZSWIM6
zinc finger, SWIM-type containing 6
chr7_-_155604967 0.069 ENST00000297261.2
SHH
sonic hedgehog
chr19_-_47220335 0.068 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2




protein kinase D2




chr17_+_57970469 0.067 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1



ribosomal protein S6 kinase, 70kDa, polypeptide 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.0 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.2 1.2 GO:0030035 microspike assembly(GO:0030035)
0.2 0.6 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.6 GO:0048880 sensory system development(GO:0048880)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.4 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.5 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.4 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.3 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.3 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:0019521 pentose-phosphate shunt, oxidative branch(GO:0009051) aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0044393 microspike(GO:0044393)
0.1 0.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling