Motif ID: UCCAGUU

Z-value: 0.405


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145-5p MIMAT0000437
hsa-miR-5195-3p MIMAT0021127



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_151561085 1.247 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr7_+_5632436 1.171 ENST00000340250.6
ENST00000382361.3
FSCN1

fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

chr7_+_100770328 1.107 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr17_+_70117153 0.954 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr12_+_4382917 0.875 ENST00000261254.3
CCND2
cyclin D2
chr11_-_119599794 0.690 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr7_-_83824169 0.593 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_125348448 0.584 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr7_+_130126012 0.551 ENST00000341441.5
MEST
mesoderm specific transcript
chr15_-_52821247 0.540 ENST00000399231.3
ENST00000399233.2
MYO5A

myosin VA (heavy chain 12, myoxin)

chr8_+_26435359 0.452 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr5_-_157002775 0.451 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr12_-_124018252 0.442 ENST00000376874.4
RILPL1
Rab interacting lysosomal protein-like 1
chr15_+_52121822 0.413 ENST00000558455.1
ENST00000308580.7
TMOD3

tropomodulin 3 (ubiquitous)

chr10_-_74856608 0.399 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1





prolyl 4-hydroxylase, alpha polypeptide I





chr3_+_47324424 0.393 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr15_+_67358163 0.388 ENST00000327367.4
SMAD3
SMAD family member 3
chr2_+_9346892 0.374 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr15_-_34628951 0.372 ENST00000397707.2
ENST00000560611.1
SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr19_+_16187085 0.371 ENST00000300933.4
TPM4
tropomyosin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0030035 microspike assembly(GO:0030035)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 1.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.0 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.0 0.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.6 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.6 GO:0048880 sensory system development(GO:0048880)
0.1 0.5 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.4 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.4 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0044393 microspike(GO:0044393)
0.1 0.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0089701 U2AF(GO:0089701)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.2 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.7 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.0 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras