Motif ID: UCACAGU

Z-value: 0.443


Mature miRNA associated with seed UCACAGU:

NamemiRBase Accession
hsa-miR-27a-3p MIMAT0000084
hsa-miR-27b-3p MIMAT0000419



Activity profile for motif UCACAGU.

activity profile for motif UCACAGU


Sorted Z-values histogram for motif UCACAGU

Sorted Z-values for motif UCACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAGU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_24911195 1.895 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr3_+_58223228 1.022 ENST00000478253.1
ENST00000295962.4
ABHD6

abhydrolase domain containing 6

chr14_+_56585048 0.861 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr14_+_67999999 0.843 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_+_76506706 0.783 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B




phosphodiesterase 8B




chr8_+_40010989 0.702 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr14_+_100259666 0.696 ENST00000262233.6
ENST00000334192.4
EML1

echinoderm microtubule associated protein like 1

chr14_-_92413727 0.690 ENST00000267620.10
FBLN5
fibulin 5
chr17_+_55333876 0.654 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr5_-_57756087 0.623 ENST00000274289.3
PLK2
polo-like kinase 2
chr6_+_19837592 0.605 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr5_+_50678921 0.596 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr19_+_32896697 0.588 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr11_-_74109422 0.581 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr6_-_39197226 0.574 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr1_-_92351769 0.563 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr13_+_24734844 0.541 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr20_-_50419055 0.540 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr4_-_107957454 0.538 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr9_-_3525968 0.531 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.7 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.7 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 0.6 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.1 0.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.1 0.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.5 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.5 GO:0043584 nose development(GO:0043584)
0.0 0.5 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.0 0.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE Genes involved in Phospholipase C-mediated cascade