Motif ID: UBP1

Z-value: 0.370


Transcription factors associated with UBP1:

Gene SymbolEntrez IDGene Name
UBP1 ENSG00000153560.7 UBP1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
UBP1hg19_v2_chr3_-_33481835_33481905-0.573.7e-03Click!


Activity profile for motif UBP1.

activity profile for motif UBP1


Sorted Z-values histogram for motif UBP1

Sorted Z-values for motif UBP1



Network of associatons between targets according to the STRING database.



First level regulatory network of UBP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_38071615 1.670 ENST00000215909.5
 LGALS1
lectin, galactoside-binding, soluble, 1
chr4_-_57524061 1.110 ENST00000508121.1
 HOPX
HOP homeobox
chr19_-_51538148 1.070 ENST00000319590.4
ENST00000250351.4
 KLK12

kallikrein-related peptidase 12

chr12_-_47473425 0.978 ENST00000550413.1
 AMIGO2
adhesion molecule with Ig-like domain 2
chr19_+_917287 0.924 ENST00000592648.1
ENST00000234371.5
 KISS1R

KISS1 receptor

chr17_+_74381343 0.899 ENST00000392496.3
 SPHK1
sphingosine kinase 1
chr2_+_228678550 0.738 ENST00000409189.3
ENST00000358813.4
 CCL20

chemokine (C-C motif) ligand 20

chr17_-_5138099 0.687 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
 SCIMP



SLP adaptor and CSK interacting membrane protein



chr12_-_8815215 0.614 ENST00000544889.1
ENST00000543369.1
 MFAP5

microfibrillar associated protein 5

chr12_-_8815299 0.599 ENST00000535336.1
 MFAP5
microfibrillar associated protein 5
chr9_-_35685452 0.574 ENST00000607559.1
 TPM2
tropomyosin 2 (beta)
chr1_-_150208320 0.525 ENST00000534220.1
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_47473369 0.484 ENST00000546455.1
 PCED1B
PC-esterase domain containing 1B
chr19_+_41257084 0.477 ENST00000601393.1
 SNRPA
small nuclear ribonucleoprotein polypeptide A
chr11_-_102668879 0.470 ENST00000315274.6
 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_100041527 0.426 ENST00000324341.1
 FAM71C
family with sequence similarity 71, member C
chr2_-_89442621 0.399 ENST00000492167.1
 IGKV3-20
immunoglobulin kappa variable 3-20
chr10_-_75676400 0.346 ENST00000412307.2
 C10orf55
chromosome 10 open reading frame 55
chr13_-_23949671 0.342 ENST00000402364.1
 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_-_150208291 0.325 ENST00000533654.1
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_-_65253506 0.321 ENST00000427538.1
 VSIG4
V-set and immunoglobulin domain containing 4
chr5_+_95998070 0.311 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
 CAST


calpastatin


chr1_-_150208363 0.302 ENST00000436748.2
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_49864746 0.301 ENST00000598810.1
 TEAD2
TEA domain family member 2
chr2_+_17721920 0.265 ENST00000295156.4
 VSNL1
visinin-like 1
chr17_+_48450575 0.254 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
 EME1


essential meiotic structure-specific endonuclease 1


chr21_+_43823983 0.250 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
 UBASH3A



ubiquitin associated and SH3 domain containing A



chr3_+_111718173 0.248 ENST00000494932.1
 TAGLN3
transgelin 3
chr11_-_11374904 0.241 ENST00000528848.2
 CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr15_-_101835110 0.235 ENST00000560496.1
 SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr6_+_31555045 0.216 ENST00000396101.3
ENST00000490742.1
 LST1

leukocyte specific transcript 1

chr4_+_156587979 0.204 ENST00000511507.1
 GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr16_+_29823427 0.200 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
 PRRT2


proline-rich transmembrane protein 2


chr1_+_206223941 0.197 ENST00000367126.4
 AVPR1B
arginine vasopressin receptor 1B
chr3_+_111718036 0.185 ENST00000455401.2
 TAGLN3
transgelin 3
chr1_-_150208412 0.185 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
 ANP32E



acidic (leucine-rich) nuclear phosphoprotein 32 family, member E



chr6_-_29395509 0.168 ENST00000377147.2
 OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr6_-_47009996 0.157 ENST00000371243.2
 GPR110
G protein-coupled receptor 110
chr6_+_29429217 0.155 ENST00000396792.2
 OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr5_+_34656331 0.148 ENST00000265109.3
 RAI14
retinoic acid induced 14
chr12_+_123717967 0.146 ENST00000536130.1
ENST00000546132.1
 C12orf65

chromosome 12 open reading frame 65

chr5_+_150051149 0.143 ENST00000523553.1
 MYOZ3
myozenin 3
chr19_-_11039188 0.138 ENST00000588347.1
 YIPF2
Yip1 domain family, member 2
chr2_-_2334888 0.131 ENST00000428368.2
ENST00000399161.2
 MYT1L

myelin transcription factor 1-like

chr2_+_61244697 0.131 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
 PEX13


peroxisomal biogenesis factor 13


chr17_-_48450534 0.129 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
 MRPL27


mitochondrial ribosomal protein L27


chrX_+_38420623 0.125 ENST00000378482.2
 TSPAN7
tetraspanin 7
chrX_+_78426469 0.121 ENST00000276077.1
 GPR174
G protein-coupled receptor 174
chr8_-_66474884 0.120 ENST00000520902.1
 CTD-3025N20.2
CTD-3025N20.2
chr1_-_150208498 0.116 ENST00000314136.8
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_-_75330537 0.114 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
 PROX2


prospero homeobox 2


chr11_-_60623437 0.111 ENST00000332539.4
 PTGDR2
prostaglandin D2 receptor 2
chr1_-_156217875 0.107 ENST00000292291.5
 PAQR6
progestin and adipoQ receptor family member VI
chr19_-_54784937 0.104 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
 LILRB2


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2


chr4_+_156588115 0.102 ENST00000455639.2
 GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr1_+_155108294 0.102 ENST00000303343.8
ENST00000368404.4
ENST00000368401.5
 SLC50A1


solute carrier family 50 (sugar efflux transporter), member 1


chr1_-_153599732 0.102 ENST00000392623.1
 S100A13
S100 calcium binding protein A13
chr15_+_28624878 0.093 ENST00000450328.2
 GOLGA8F
golgin A8 family, member F
chr11_-_113345995 0.086 ENST00000355319.2
ENST00000542616.1
 DRD2

dopamine receptor D2

chr8_-_107782463 0.085 ENST00000311955.3
 ABRA
actin-binding Rho activating protein
chr3_+_111260980 0.081 ENST00000438817.2
 CD96
CD96 molecule
chr8_+_77593448 0.079 ENST00000521891.2
 ZFHX4
zinc finger homeobox 4
chr4_+_156587853 0.074 ENST00000506455.1
ENST00000511108.1
 GUCY1A3

guanylate cyclase 1, soluble, alpha 3

chr12_+_123717458 0.072 ENST00000253233.1
 C12orf65
chromosome 12 open reading frame 65
chr12_+_101188547 0.072 ENST00000546991.1
ENST00000392979.3
 ANO4

anoctamin 4

chr9_+_15422702 0.071 ENST00000380821.3
ENST00000421710.1
 SNAPC3

small nuclear RNA activating complex, polypeptide 3, 50kDa

chr22_+_22730353 0.069 ENST00000390296.2
 IGLV5-45
immunoglobulin lambda variable 5-45
chr1_-_182369751 0.069 ENST00000367565.1
 TEDDM1
transmembrane epididymal protein 1
chr7_+_132937820 0.064 ENST00000393161.2
ENST00000253861.4
 EXOC4

exocyst complex component 4

chrX_+_139791917 0.061 ENST00000607004.1
ENST00000370535.3
 LINC00632

long intergenic non-protein coding RNA 632

chr15_+_81475047 0.059 ENST00000559388.1
 IL16
interleukin 16
chr11_+_10326612 0.058 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
 ADM





adrenomedullin





chr14_+_21214039 0.058 ENST00000326842.2
 EDDM3A
epididymal protein 3A
chr3_+_111260954 0.051 ENST00000283285.5
 CD96
CD96 molecule
chr19_-_11039261 0.051 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
 YIPF2





Yip1 domain family, member 2





chr2_+_162087577 0.050 ENST00000439442.1
 TANK
TRAF family member-associated NFKB activator
chr20_+_59654146 0.047 ENST00000441660.1
 RP5-827L5.1
RP5-827L5.1
chr2_+_113033164 0.041 ENST00000409871.1
ENST00000343936.4
 ZC3H6

zinc finger CCCH-type containing 6

chr1_-_182641367 0.039 ENST00000508450.1
 RGS8
regulator of G-protein signaling 8
chr11_+_7506713 0.038 ENST00000329293.3
ENST00000534244.1
 OLFML1

olfactomedin-like 1

chr5_-_41510656 0.037 ENST00000377801.3
 PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr1_+_48688357 0.035 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
 SLC5A9



solute carrier family 5 (sodium/sugar cotransporter), member 9



chr22_+_22676808 0.032 ENST00000390290.2
 IGLV1-51
immunoglobulin lambda variable 1-51
chr10_-_27443294 0.029 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
 YME1L1



YME1-like 1 ATPase



chr16_-_75301886 0.019 ENST00000393422.2
 BCAR1
breast cancer anti-estrogen resistance 1
chr1_-_152332480 0.016 ENST00000388718.5
 FLG2
filaggrin family member 2
chr22_+_22385332 0.007 ENST00000390282.2
 IGLV4-69
immunoglobulin lambda variable 4-69
chr5_-_131329918 0.006 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
 ACSL6


acyl-CoA synthetase long-chain family member 6


chr3_+_111260856 0.005 ENST00000352690.4
 CD96
CD96 molecule
chr9_-_130497565 0.004 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
 TOR2A



torsin family 2, member A



chr1_-_168698433 0.002 ENST00000367817.3
 DPT
dermatopontin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.7 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.4 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 1.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 1.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.5 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0030395 lactose binding(GO:0030395)
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.2 PID_NOTCH_PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines