Motif ID: UAGUGUU

Z-value: 0.729





Activity profile for motif UAGUGUU.

activity profile for motif UAGUGUU


Sorted Z-values histogram for motif UAGUGUU

Sorted Z-values for motif UAGUGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAGUGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_25102252 2.732 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_-_39219705 2.062 ENST00000351578.6
FYB
FYN binding protein
chr20_+_37554955 1.695 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr7_+_36429409 1.361 ENST00000265748.2
ANLN
anillin, actin binding protein
chr2_-_113542063 1.330 ENST00000263339.3
IL1A
interleukin 1, alpha
chr12_-_54813229 1.275 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr22_+_33197683 1.266 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr20_-_23030296 1.219 ENST00000377103.2
THBD
thrombomodulin
chr14_-_35182994 1.152 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr3_+_172468472 1.063 ENST00000232458.5
ENST00000392692.3
ECT2

epithelial cell transforming sequence 2 oncogene

chr1_+_182992545 1.042 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_+_47324424 0.964 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr4_-_80994210 0.920 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr7_-_98741642 0.900 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr9_+_131644388 0.889 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr14_+_55034599 0.870 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr1_+_40420802 0.846 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A



major facilitator superfamily domain containing 2A



chr3_-_98620500 0.825 ENST00000326840.6
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr10_+_76871454 0.813 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr9_-_113800317 0.802 ENST00000374431.3
LPAR1
lysophosphatidic acid receptor 1
chr2_+_102508955 0.797 ENST00000414004.2
FLJ20373
FLJ20373
chr11_-_65667884 0.751 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr1_-_244013384 0.726 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_-_25019760 0.725 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr17_+_26662730 0.702 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr16_-_85722530 0.692 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr4_-_41216619 0.679 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr17_-_1395954 0.675 ENST00000359786.5
MYO1C
myosin IC
chr21_+_34775181 0.666 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_+_114178512 0.662 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_178694300 0.648 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr3_+_150126101 0.645 ENST00000361875.3
ENST00000361136.2
TSC22D2

TSC22 domain family, member 2

chr8_-_145013711 0.639 ENST00000345136.3
PLEC
plectin
chr17_+_2699697 0.626 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2


RAP1 GTPase activating protein 2


chr15_+_38544476 0.613 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr18_+_42260861 0.609 ENST00000282030.5
SETBP1
SET binding protein 1
chr9_-_99180597 0.607 ENST00000375256.4
ZNF367
zinc finger protein 367
chr1_-_155942086 0.561 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr5_-_132299313 0.551 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr17_-_17875688 0.538 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2







target of myb1-like 2 (chicken)







chr1_-_231560790 0.529 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr1_+_7831323 0.528 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr5_-_76788317 0.497 ENST00000296679.4
WDR41
WD repeat domain 41
chr2_+_208576355 0.495 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1


cyclin Y-like 1


chr1_-_29450399 0.494 ENST00000521452.1
TMEM200B
transmembrane protein 200B
chr12_+_100967420 0.490 ENST00000266754.5
ENST00000547754.1
GAS2L3

growth arrest-specific 2 like 3

chr1_-_179198702 0.483 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr10_-_99447024 0.483 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr4_+_128703295 0.469 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr8_+_126442563 0.467 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr1_+_25071848 0.457 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr12_-_53625958 0.456 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG



retinoic acid receptor, gamma



chr2_+_234160217 0.449 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1




autophagy related 16-like 1 (S. cerevisiae)




chr8_-_28243934 0.428 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chrX_-_128977781 0.425 ENST00000357166.6
ZDHHC9
zinc finger, DHHC-type containing 9
chr11_+_118477144 0.425 ENST00000361417.2
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr22_-_36236265 0.423 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr19_-_4400415 0.422 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1


SH3-domain GRB2-like 1


chr5_+_72251793 0.420 ENST00000430046.2
ENST00000341845.6
FCHO2

FCH domain only 2

chr1_+_78245303 0.416 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr3_+_171758344 0.409 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr4_+_15004165 0.402 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2


cytoplasmic polyadenylation element binding protein 2


chr6_-_30712313 0.402 ENST00000376377.2
ENST00000259874.5
IER3

immediate early response 3

chr1_-_179846928 0.394 ENST00000367612.3
ENST00000609928.1
TOR1AIP2

torsin A interacting protein 2

chr8_-_92053212 0.391 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chrX_-_41782249 0.388 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chr12_+_56915713 0.387 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr11_+_69455855 0.373 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr1_+_52682052 0.362 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr7_-_23510086 0.360 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_165697920 0.356 ENST00000342193.4
ENST00000375458.2
COBLL1

cordon-bleu WH2 repeat protein-like 1

chr16_+_3070313 0.351 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr7_+_106505912 0.350 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr6_+_118228657 0.345 ENST00000360388.4
SLC35F1
solute carrier family 35, member F1
chr13_+_76123883 0.343 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr8_-_125384927 0.343 ENST00000297632.6
TMEM65
transmembrane protein 65
chr12_+_49761224 0.337 ENST00000553127.1
ENST00000321898.6
SPATS2

spermatogenesis associated, serine-rich 2

chr9_-_34126730 0.334 ENST00000361264.4
DCAF12
DDB1 and CUL4 associated factor 12
chr6_+_35310312 0.323 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD



peroxisome proliferator-activated receptor delta



chr18_+_59854480 0.323 ENST00000256858.6
ENST00000398130.2
KIAA1468

KIAA1468

chr17_+_79373540 0.323 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr14_+_65453432 0.321 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr20_+_17550489 0.320 ENST00000246069.7
DSTN
destrin (actin depolymerizing factor)
chr11_+_111473108 0.320 ENST00000304987.3
SIK2
salt-inducible kinase 2
chrX_-_70288234 0.318 ENST00000276105.3
ENST00000374274.3
SNX12

sorting nexin 12

chr1_+_215740709 0.317 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3
chr1_-_43424500 0.303 ENST00000415851.2
ENST00000426263.3
ENST00000372500.3
SLC2A1


solute carrier family 2 (facilitated glucose transporter), member 1


chr13_-_77460525 0.300 ENST00000377474.2
ENST00000317765.2
KCTD12

potassium channel tetramerization domain containing 12

chr1_+_186265399 0.296 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr4_-_139163491 0.294 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr19_-_18632861 0.293 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr6_+_11094266 0.289 ENST00000416247.2
SMIM13
small integral membrane protein 13
chr2_+_196521458 0.288 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr1_-_38325256 0.287 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr20_+_57766075 0.282 ENST00000371030.2
ZNF831
zinc finger protein 831
chr2_-_209119831 0.277 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr17_-_62658186 0.277 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr3_-_176914238 0.276 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr12_+_107168342 0.273 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr7_-_123389104 0.273 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chrX_+_48916497 0.272 ENST00000496529.2
ENST00000376396.3
ENST00000422185.2
ENST00000603986.1
ENST00000536628.2
CCDC120




coiled-coil domain containing 120




chr19_-_48894762 0.271 ENST00000600980.1
ENST00000330720.2
KDELR1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr12_+_88536067 0.269 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
TMTC3


transmembrane and tetratricopeptide repeat containing 3


chr9_+_101867359 0.267 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr9_+_110045537 0.267 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr12_-_121342170 0.261 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr8_+_11141925 0.260 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr1_+_65613217 0.251 ENST00000545314.1
AK4
adenylate kinase 4
chr5_-_147162078 0.246 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr3_-_195808952 0.242 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC



transferrin receptor



chr10_+_134351319 0.238 ENST00000368594.3
ENST00000368593.3
INPP5A

inositol polyphosphate-5-phosphatase, 40kDa

chr15_+_59063478 0.235 ENST00000559228.1
ENST00000450403.2
FAM63B

family with sequence similarity 63, member B

chr12_-_93323013 0.233 ENST00000322349.8
EEA1
early endosome antigen 1
chr5_-_142783175 0.232 ENST00000231509.3
ENST00000394464.2
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr2_-_39348137 0.228 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr1_-_243418344 0.226 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr9_-_123964114 0.220 ENST00000373840.4
RAB14
RAB14, member RAS oncogene family
chr1_+_200708671 0.216 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr6_-_24721054 0.213 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr7_-_14029515 0.203 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chr12_-_6451235 0.202 ENST00000440083.2
ENST00000162749.2
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr9_-_73029540 0.201 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr1_-_156542328 0.197 ENST00000361170.2
IQGAP3
IQ motif containing GTPase activating protein 3
chr10_-_120514720 0.195 ENST00000369151.3
ENST00000340214.4
CACUL1

CDK2-associated, cullin domain 1

chr5_-_156486120 0.195 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr5_+_82767284 0.194 ENST00000265077.3
VCAN
versican
chr1_+_78470530 0.192 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_57583130 0.191 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr15_+_66161871 0.190 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr14_+_103058948 0.189 ENST00000262241.6
RCOR1
REST corepressor 1
chr17_-_49198216 0.184 ENST00000262013.7
ENST00000357122.4
SPAG9

sperm associated antigen 9

chr6_+_25279651 0.183 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chrX_+_24483338 0.181 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr4_+_99916765 0.179 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr17_+_5185552 0.179 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1




rabaptin, RAB GTPase binding effector protein 1




chr1_+_199996702 0.176 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr14_-_74253948 0.173 ENST00000394071.2
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr2_+_198669365 0.171 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr3_-_72496035 0.170 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr10_-_119806085 0.169 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr2_+_182756615 0.168 ENST00000431877.2
ENST00000320370.7
SSFA2

sperm specific antigen 2

chr3_-_196014520 0.164 ENST00000441879.1
ENST00000292823.2
ENST00000411591.1
ENST00000431016.1
ENST00000443555.1
PCYT1A




phosphate cytidylyltransferase 1, choline, alpha




chr9_+_71394945 0.162 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr16_-_23160591 0.159 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr15_+_85523671 0.159 ENST00000310298.4
ENST00000557957.1
PDE8A

phosphodiesterase 8A

chr7_-_66460563 0.152 ENST00000246868.2
SBDS
Shwachman-Bodian-Diamond syndrome
chr1_+_186798073 0.151 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chr5_-_16936340 0.150 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr3_+_101292939 0.149 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PCNP


PEST proteolytic signal containing nuclear protein


chr5_+_179159813 0.146 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr2_-_183903133 0.143 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr17_+_38375574 0.141 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr18_+_43753974 0.137 ENST00000282059.6
ENST00000321319.6
C18orf25

chromosome 18 open reading frame 25

chr12_+_19592602 0.133 ENST00000398864.3
ENST00000266508.9
AEBP2

AE binding protein 2

chr10_+_75757863 0.128 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL


vinculin


chr6_-_74363803 0.125 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chr11_-_65381643 0.125 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr6_+_163835669 0.125 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI



QKI, KH domain containing, RNA binding



chr3_-_50396978 0.123 ENST00000266025.3
TMEM115
transmembrane protein 115
chr15_+_90931450 0.123 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQGAP1


IQ motif containing GTPase activating protein 1


chr17_+_79650962 0.123 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr15_-_101142362 0.122 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS





lines homolog (Drosophila)





chr11_-_76381781 0.122 ENST00000260061.5
ENST00000404995.1
LRRC32

leucine rich repeat containing 32

chr10_-_104262426 0.119 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chrX_+_146993449 0.119 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1


fragile X mental retardation 1


chr4_+_113970772 0.118 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2



ankyrin 2, neuronal



chr7_+_20370746 0.118 ENST00000222573.4
ITGB8
integrin, beta 8
chr1_+_87170247 0.118 ENST00000370558.4
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr11_+_57520715 0.115 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1



catenin (cadherin-associated protein), delta 1



chr1_-_68299130 0.113 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr1_-_31538517 0.111 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1







pumilio RNA-binding family member 1







chrX_-_11445856 0.111 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr3_+_85008089 0.110 ENST00000383699.3
CADM2
cell adhesion molecule 2
chr9_+_133454943 0.104 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr17_-_45266542 0.104 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27




cell division cycle 27




chr10_-_11653753 0.101 ENST00000609104.1
USP6NL
USP6 N-terminal like
chrX_+_99839799 0.101 ENST00000373031.4
TNMD
tenomodulin
chr8_-_37756972 0.099 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1


RAB11 family interacting protein 1 (class I)


chr4_-_90229142 0.099 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr9_+_114423615 0.094 ENST00000374293.4
GNG10
guanine nucleotide binding protein (G protein), gamma 10
chr2_-_61765315 0.094 ENST00000406957.1
ENST00000401558.2
XPO1

exportin 1 (CRM1 homolog, yeast)

chr17_+_4710391 0.094 ENST00000263088.6
ENST00000572940.1
PLD2

phospholipase D2

chr3_+_100428268 0.092 ENST00000240851.4
TFG
TRK-fused gene
chr4_+_145567173 0.092 ENST00000296575.3
HHIP
hedgehog interacting protein
chr10_-_15762124 0.089 ENST00000378076.3
ITGA8
integrin, alpha 8
chr4_-_185747188 0.087 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1



acyl-CoA synthetase long-chain family member 1



chr17_-_21117902 0.086 ENST00000317635.5
TMEM11
transmembrane protein 11
chr3_+_10857885 0.085 ENST00000254488.2
ENST00000454147.1
SLC6A11

solute carrier family 6 (neurotransmitter transporter), member 11

chr11_-_110167352 0.083 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX





radixin





chr19_+_18794470 0.082 ENST00000321949.8
ENST00000338797.6
CRTC1

CREB regulated transcription coactivator 1

chr1_-_211752073 0.079 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr6_-_82462425 0.075 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr5_-_114961858 0.071 ENST00000456936.3
ENST00000408996.4
ENST00000282382.4
TMED7
TICAM2
TMED7-TICAM2
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
TMED7-TICAM2 readthrough
chr6_-_52441713 0.070 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr13_-_110959478 0.065 ENST00000543140.1
ENST00000375820.4
COL4A1

collagen, type IV, alpha 1

chr22_+_21771656 0.064 ENST00000407464.2
HIC2
hypermethylated in cancer 2
chr15_-_51058005 0.062 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chr8_-_62627057 0.062 ENST00000519234.1
ENST00000379449.6
ENST00000379454.4
ENST00000518068.1
ENST00000517856.1
ENST00000356457.5
ASPH





aspartate beta-hydroxylase





chr6_-_111136513 0.060 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr7_-_75988321 0.059 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5 1.4 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.3 1.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 0.9 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.3 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.2 0.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.6 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 0.5 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.6 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.3 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.4 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.9 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 1.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.5 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.4 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.3 GO:0072672 neutrophil extravasation(GO:0072672)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.3 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.1 0.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 1.5 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.4 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 1.7 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.5 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.7 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 1.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.2 1.1 GO:0097149 centralspindlin complex(GO:0097149)
0.2 0.7 GO:0000811 GINS complex(GO:0000811)
0.2 0.7 GO:0045160 myosin I complex(GO:0045160)
0.2 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 1.0 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0001939 female pronucleus(GO:0001939)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.3 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 1.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 2.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 2.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 1.8 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 3.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.7 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.4 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.1 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.3 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex