Motif ID: TBX21_TBR1

Z-value: 1.056

Transcription factors associated with TBX21_TBR1:

Gene SymbolEntrez IDGene Name
TBR1 ENSG00000136535.10 TBR1
TBX21 ENSG00000073861.2 TBX21

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX21hg19_v2_chr17_+_45810594_45810610-0.433.5e-02Click!
TBR1hg19_v2_chr2_+_162272605_1622727530.193.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TBX21_TBR1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_94727048 10.728 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr1_+_38022572 9.897 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr1_+_38022513 8.827 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr11_+_73358594 7.429 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1


pleckstrin homology domain containing, family B (evectins) member 1


chr19_-_7990991 6.087 ENST00000318978.4
CTXN1
cortexin 1
chr4_-_177116772 4.661 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr5_-_35938674 4.630 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr7_-_120497178 3.861 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr2_+_228736321 3.734 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr11_+_6260298 3.699 ENST00000379936.2
CNGA4
cyclic nucleotide gated channel alpha 4
chr3_-_66551397 3.427 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr2_+_228736335 3.350 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chr3_-_66551351 3.262 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr3_-_100712352 3.223 ENST00000471714.1
ENST00000284322.5
ABI3BP

ABI family, member 3 (NESH) binding protein

chr16_-_67450325 2.986 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr14_+_95078714 2.600 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3


chr12_+_69742121 2.510 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ


lysozyme


chr17_-_56406117 2.510 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr5_+_140571902 2.483 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr13_-_39564993 2.453 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr19_+_36236514 2.405 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr1_+_47264711 2.396 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1


cytochrome P450, family 4, subfamily B, polypeptide 1


chr19_+_36236491 2.363 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr1_+_212782012 2.258 ENST00000341491.4
ENST00000366985.1
ATF3

activating transcription factor 3

chr17_+_35849937 2.160 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr22_+_31003133 1.945 ENST00000405742.3
TCN2
transcobalamin II
chr8_+_75896731 1.937 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr22_+_31003190 1.924 ENST00000407817.3
TCN2
transcobalamin II
chr1_-_46598371 1.851 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3




phosphoinositide-3-kinase, regulatory subunit 3 (gamma)




chrX_+_53449887 1.832 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr7_-_138386097 1.826 ENST00000421622.1
SVOPL
SVOP-like
chr1_-_26633067 1.825 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11








UBX domain protein 11








chr2_-_157189180 1.792 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr1_-_46598284 1.745 ENST00000423209.1
ENST00000262741.5
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr9_-_75567962 1.704 ENST00000297785.3
ENST00000376939.1
ALDH1A1

aldehyde dehydrogenase 1 family, member A1

chr12_+_56473939 1.688 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr16_+_30212378 1.609 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr9_+_26956371 1.574 ENST00000380062.5
ENST00000518614.1
IFT74

intraflagellar transport 74 homolog (Chlamydomonas)

chr1_+_182758900 1.568 ENST00000367555.1
ENST00000367554.3
NPL

N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

chr11_-_47736896 1.565 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2




ATP/GTP binding protein-like 2




chr5_-_68628543 1.545 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
CCDC125


coiled-coil domain containing 125


chr10_+_118305435 1.540 ENST00000369221.2
PNLIP
pancreatic lipase
chr6_-_52705641 1.490 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr10_+_114135004 1.486 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_7232585 1.413 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4



neuralized E3 ubiquitin protein ligase 4



chrX_+_53449805 1.408 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr6_+_39760129 1.382 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr11_+_45907177 1.331 ENST00000241014.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr14_+_77582905 1.300 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr2_+_98703643 1.296 ENST00000477737.1
VWA3B
von Willebrand factor A domain containing 3B
chr4_-_70518941 1.292 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr1_+_16062820 1.271 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr15_-_83316254 1.260 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr1_-_108743471 1.237 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr11_+_17756279 1.233 ENST00000265969.6
KCNC1
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr12_-_57443886 1.225 ENST00000300119.3
MYO1A
myosin IA
chr12_-_90024360 1.205 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr5_-_74807418 1.199 ENST00000405807.4
ENST00000261415.7
COL4A3BP

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chrX_+_105412290 1.192 ENST00000357175.2
ENST00000337685.2
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr10_+_45406627 1.191 ENST00000389583.4
TMEM72
transmembrane protein 72
chr19_-_50529193 1.189 ENST00000596445.1
ENST00000599538.1
VRK3

vaccinia related kinase 3

chr20_+_44098346 1.139 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr11_+_64073699 1.139 ENST00000405666.1
ENST00000468670.1
ESRRA

estrogen-related receptor alpha

chr7_-_138363824 1.113 ENST00000419765.3
SVOPL
SVOP-like
chr1_-_85930246 1.101 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_-_33913708 1.069 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr7_-_100026280 1.035 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1



zinc finger, CW type with PWWP domain 1



chr6_-_13487825 1.023 ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr6_+_167738569 0.991 ENST00000239587.5
TTLL2
tubulin tyrosine ligase-like family, member 2
chrX_-_132549506 0.963 ENST00000370828.3
GPC4
glypican 4
chr11_-_6440624 0.956 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr15_+_41913690 0.925 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr11_-_236326 0.921 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
SIRT3




sirtuin 3




chr12_+_12202774 0.910 ENST00000589718.1
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr7_-_87849340 0.909 ENST00000419179.1
ENST00000265729.2
SRI

sorcin

chr12_+_12202785 0.908 ENST00000586576.1
ENST00000464885.2
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr20_+_44098385 0.889 ENST00000217425.5
ENST00000339946.3
WFDC2

WAP four-disulfide core domain 2

chr17_+_30771279 0.885 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11



proteasome (prosome, macropain) 26S subunit, non-ATPase, 11



chr1_+_40840320 0.860 ENST00000372708.1
SMAP2
small ArfGAP2
chr6_-_46922659 0.849 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr11_+_129685707 0.848 ENST00000281441.3
TMEM45B
transmembrane protein 45B
chr16_+_53133070 0.822 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr19_+_859425 0.820 ENST00000327726.6
CFD
complement factor D (adipsin)
chr14_-_76447494 0.813 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr8_+_104831554 0.804 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr22_-_31688381 0.785 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr5_+_98104978 0.785 ENST00000308234.7
RGMB
repulsive guidance molecule family member b
chr11_-_133826852 0.778 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr1_+_147013182 0.773 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr16_-_81110683 0.773 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46


chromosome 16 open reading frame 46


chr6_+_131894284 0.771 ENST00000368087.3
ENST00000356962.2
ARG1

arginase 1

chr15_-_43559055 0.763 ENST00000220420.5
ENST00000349114.4
TGM5

transglutaminase 5

chr11_+_65266507 0.755 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr15_+_67547163 0.745 ENST00000335894.4
IQCH
IQ motif containing H
chr1_-_1009683 0.743 ENST00000453464.2
RNF223
ring finger protein 223
chr14_-_65569244 0.734 ENST00000557277.1
ENST00000556892.1
MAX

MYC associated factor X

chr1_+_155099927 0.732 ENST00000368407.3
EFNA1
ephrin-A1
chr11_+_61447845 0.727 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr20_-_271009 0.723 ENST00000382369.5
C20orf96
chromosome 20 open reading frame 96
chr12_-_107380910 0.721 ENST00000392830.2
ENST00000240050.4
MTERFD3

MTERF domain containing 3

chr2_+_219247021 0.716 ENST00000539932.1
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr11_-_76155700 0.705 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr6_-_84937314 0.696 ENST00000257766.4
ENST00000403245.3
KIAA1009

KIAA1009

chr19_+_859654 0.690 ENST00000592860.1
CFD
complement factor D (adipsin)
chr4_+_160188889 0.689 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_-_115124257 0.684 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr11_-_44972476 0.681 ENST00000527685.1
ENST00000308212.5
TP53I11

tumor protein p53 inducible protein 11

chr12_-_107380846 0.675 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3


MTERF domain containing 3


chr15_-_52030293 0.669 ENST00000560491.1
ENST00000267838.3
LYSMD2

LysM, putative peptidoglycan-binding, domain containing 2

chr12_-_91576429 0.664 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr2_-_40679186 0.661 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_+_695888 0.659 ENST00000441152.2
PRR26
proline rich 26
chr17_+_76311791 0.648 ENST00000586321.1
AC061992.2
AC061992.2
chr2_-_152146385 0.644 ENST00000414946.1
ENST00000243346.5
NMI

N-myc (and STAT) interactor

chr4_+_74735102 0.642 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr3_-_46505137 0.631 ENST00000426532.2
ENST00000415180.1
LTF

lactotransferrin

chr3_-_146213722 0.628 ENST00000336685.2
ENST00000489015.1
PLSCR2

phospholipid scramblase 2

chr1_-_44818599 0.622 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr12_+_32112340 0.621 ENST00000540924.1
ENST00000312561.4
KIAA1551

KIAA1551

chr4_-_89619386 0.615 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr6_-_154751629 0.612 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr12_-_91348949 0.608 ENST00000358859.2
CCER1
coiled-coil glutamate-rich protein 1
chr7_+_107110488 0.607 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr18_-_30050395 0.607 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr22_-_24110063 0.606 ENST00000520222.1
ENST00000401675.3
CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

chr12_+_58148842 0.604 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr5_+_74807581 0.594 ENST00000241436.4
ENST00000352007.5
POLK

polymerase (DNA directed) kappa

chr22_-_31688431 0.592 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr1_+_26146397 0.586 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L








mitochondrial fission regulator 1-like








chr11_-_114271139 0.582 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr17_+_58755184 0.581 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr12_-_10151773 0.581 ENST00000298527.6
ENST00000348658.4
CLEC1B

C-type lectin domain family 1, member B

chr11_+_112832202 0.579 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr3_-_49466686 0.578 ENST00000273598.3
ENST00000436744.2
NICN1

nicolin 1

chr2_+_27799389 0.578 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr3_-_52443799 0.570 ENST00000470173.1
ENST00000296288.5
BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

chr14_+_32546274 0.569 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr17_-_42452063 0.565 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr1_+_26146674 0.560 ENST00000525713.1
ENST00000374301.3
MTFR1L

mitochondrial fission regulator 1-like

chr1_+_174843548 0.559 ENST00000478442.1
ENST00000465412.1
RABGAP1L

RAB GTPase activating protein 1-like

chr2_-_61697862 0.556 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr19_+_3721719 0.551 ENST00000589378.1
ENST00000382008.3
TJP3

tight junction protein 3

chr21_+_25801041 0.549 ENST00000453784.2
ENST00000423581.1
AP000476.1

AP000476.1

chr17_-_20370847 0.548 ENST00000423676.3
ENST00000324290.5
LGALS9B

lectin, galactoside-binding, soluble, 9B

chr2_+_217498105 0.545 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chrX_-_19689106 0.538 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_18443703 0.532 ENST00000379996.3
CDKL5
cyclin-dependent kinase-like 5
chr16_-_88717482 0.531 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr3_-_61237050 0.530 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT



fragile histidine triad



chr2_-_175869936 0.529 ENST00000409900.3
CHN1
chimerin 1
chr3_+_142315225 0.524 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chr22_+_35776828 0.522 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chrX_-_10645773 0.514 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr5_-_34043310 0.508 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr1_+_27114418 0.508 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr8_-_27457494 0.503 ENST00000521770.1
CLU
clusterin
chr16_-_88717423 0.502 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA


cytochrome b-245, alpha polypeptide


chr17_+_25958174 0.497 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9



lectin, galactoside-binding, soluble, 9



chr19_+_1000418 0.497 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr4_+_154622652 0.489 ENST00000260010.6
TLR2
toll-like receptor 2
chr17_-_9929581 0.485 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr11_-_76155618 0.483 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr8_+_28351707 0.464 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr9_-_35815013 0.461 ENST00000259667.5
HINT2
histidine triad nucleotide binding protein 2
chr10_-_65028938 0.447 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr10_-_120355149 0.435 ENST00000239032.2
PRLHR
prolactin releasing hormone receptor
chr15_-_83316087 0.433 ENST00000568757.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr5_+_140207536 0.431 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr13_+_42031679 0.426 ENST00000379359.3
RGCC
regulator of cell cycle
chr9_-_96717654 0.423 ENST00000253968.6
BARX1
BARX homeobox 1
chr6_+_30295036 0.420 ENST00000376659.5
ENST00000428555.1
TRIM39

tripartite motif containing 39

chr6_+_108487245 0.418 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr5_+_56469843 0.409 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr12_-_56120838 0.396 ENST00000548160.1
CD63
CD63 molecule
chr9_+_17135016 0.394 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN


centlein, centrosomal protein


chr10_-_65028817 0.393 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr19_+_12862604 0.392 ENST00000553030.1
BEST2
bestrophin 2
chr4_+_26322185 0.390 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr17_-_1553346 0.386 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr14_-_20881579 0.382 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
TEP1


telomerase-associated protein 1


chr7_-_91875358 0.380 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1



KRIT1, ankyrin repeat containing



chr20_-_271304 0.378 ENST00000400269.3
ENST00000360321.2
C20orf96

chromosome 20 open reading frame 96

chr6_+_127588020 0.373 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146




ring finger protein 146




chr9_+_134378289 0.373 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1












protein-O-mannosyltransferase 1












chr17_+_76356516 0.372 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr1_+_158325684 0.370 ENST00000368162.2
CD1E
CD1e molecule
chr22_-_41215328 0.367 ENST00000434185.1
ENST00000435456.2
SLC25A17

solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17

chr15_+_60296421 0.367 ENST00000396057.4
FOXB1
forkhead box B1
chr8_-_72268968 0.360 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr17_-_56609302 0.358 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4





septin 4





chr6_+_30294612 0.356 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
TRIM39






tripartite motif containing 39






chr4_+_26322409 0.354 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr19_+_50529212 0.344 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
ZNF473


zinc finger protein 473


chr4_-_170924888 0.342 ENST00000502832.1
ENST00000393704.3
MFAP3L

microfibrillar-associated protein 3-like

chr5_+_35856951 0.341 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R



interleukin 7 receptor



chr3_+_185000729 0.339 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
MAP3K13




mitogen-activated protein kinase kinase kinase 13




chr8_-_61193947 0.338 ENST00000317995.4
CA8
carbonic anhydrase VIII
chr5_-_145562147 0.337 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS



leucyl-tRNA synthetase



chr6_+_32132360 0.336 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8


EGF-like-domain, multiple 8


chr4_+_108745711 0.336 ENST00000394684.4
SGMS2
sphingomyelin synthase 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.8 2.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.6 1.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 1.8 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4 1.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.4 3.7 GO:0015889 cobalamin transport(GO:0015889)
0.3 2.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.3 1.6 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.3 1.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3 1.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 1.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 1.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 0.8 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.2 0.7 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 1.6 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 0.7 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 4.7 GO:0007220 Notch receptor processing(GO:0007220)
0.2 0.6 GO:0033214 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.2 0.7 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.2 0.5 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.2 2.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.5 GO:0042495 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 0.5 GO:0071106 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.2 0.5 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 1.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 1.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.4 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 3.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 2.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.7 GO:0014028 notochord formation(GO:0014028)
0.1 1.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 4.0 GO:0010842 retina layer formation(GO:0010842)
0.1 0.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.3 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 1.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.3 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 1.2 GO:0015866 ADP transport(GO:0015866)
0.1 7.6 GO:0007602 phototransduction(GO:0007602)
0.1 0.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 3.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.5 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.5 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.5 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 2.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.1 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 1.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.6 GO:0033630 keratinocyte development(GO:0003334) positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 1.5 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.8 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.2 GO:0061010 common bile duct development(GO:0061009) gall bladder development(GO:0061010)
0.1 0.3 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 7.8 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.8 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.2 GO:2000078 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.3 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 1.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.3 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.1 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.5 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.6 GO:0015871 choline transport(GO:0015871)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.8 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.8 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:1902624 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.6 GO:0030220 platelet formation(GO:0030220)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) chylomicron assembly(GO:0034378)
0.0 1.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.3 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 1.9 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.4 4.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 18.7 GO:0030286 dynein complex(GO:0030286)
0.2 1.9 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.6 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 3.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.9 GO:0044326 dendritic spine neck(GO:0044326)
0.1 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 3.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 0.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 5.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.0 1.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 4.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 8.0 GO:0005929 cilium(GO:0005929)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0035580 specific granule lumen(GO:0035580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 18.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.5 1.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 3.7 GO:0031419 cobalamin binding(GO:0031419)
0.3 2.0 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 3.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 0.9 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.3 1.6 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 1.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 1.2 GO:0097001 ceramide binding(GO:0097001)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.0 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 4.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 2.5 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.5 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 2.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.7 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 3.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.0 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 3.1 GO:0030552 cAMP binding(GO:0030552)
0.1 0.7 GO:0000150 recombinase activity(GO:0000150)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.7 GO:0016594 glycine binding(GO:0016594)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0031730 CCR1 chemokine receptor binding(GO:0031726) CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 3.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 9.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.9 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.2 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 4.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 2.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.8 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 3.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 1.5 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.3 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.5 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.1 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 2.2 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 2.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 5.0 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME_DEFENSINS Genes involved in Defensins
0.0 0.4 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells