Motif ID: TBX15_MGA

Z-value: 0.562

Transcription factors associated with TBX15_MGA:

Gene SymbolEntrez IDGene Name
MGA ENSG00000174197.12 MGA
TBX15 ENSG00000092607.9 TBX15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MGAhg19_v2_chr15_+_41952591_41952672-0.491.5e-02Click!
TBX15hg19_v2_chr1_-_119532127_119532179,
hg19_v2_chr1_-_119530428_119530572
0.203.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TBX15_MGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153066998 1.958 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr21_+_30502806 1.691 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr14_+_75746781 1.354 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr4_+_8582287 1.156 ENST00000382487.4
GPR78
G protein-coupled receptor 78
chr1_-_153029980 1.062 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr1_-_153044083 1.008 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr7_-_76255444 0.936 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_+_15736359 0.907 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr7_+_143013198 0.870 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr7_-_27135591 0.866 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr14_+_67291158 0.826 ENST00000555456.1
GPHN
gephyrin
chr2_-_31637560 0.811 ENST00000379416.3
XDH
xanthine dehydrogenase
chr18_+_47088401 0.792 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr17_+_9066252 0.777 ENST00000436734.1
NTN1
netrin 1
chr5_+_133861339 0.775 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr7_-_142120321 0.752 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr1_+_150522222 0.742 ENST00000369039.5
ADAMTSL4
ADAMTS-like 4
chr9_+_139847347 0.733 ENST00000371632.3
LCN12
lipocalin 12
chrX_+_99899180 0.732 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr11_-_119599794 0.719 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr17_-_39216344 0.710 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr20_+_62492566 0.697 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr9_+_34990219 0.680 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr11_-_7847519 0.662 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chrX_-_153775426 0.638 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr19_+_39279838 0.631 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr20_+_44509857 0.580 ENST00000372523.1
ENST00000372520.1
ZSWIM1

zinc finger, SWIM-type containing 1

chr10_+_95256356 0.570 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr3_-_197024394 0.568 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1




discs, large homolog 1 (Drosophila)




chr1_-_11907829 0.557 ENST00000376480.3
NPPA
natriuretic peptide A
chr4_-_57547870 0.554 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX



HOP homeobox



chr1_-_205744205 0.550 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr22_-_20231207 0.547 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr5_-_132112907 0.528 ENST00000458488.2
SEPT8
septin 8
chr5_-_132112921 0.495 ENST00000378721.4
ENST00000378701.1
SEPT8

septin 8

chrX_+_69642881 0.488 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr21_+_37507210 0.479 ENST00000290354.5
CBR3
carbonyl reductase 3
chr12_-_57634475 0.478 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_-_111174054 0.472 ENST00000369770.3
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr17_-_40333099 0.464 ENST00000607371.1
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr5_+_137514687 0.462 ENST00000394894.3
KIF20A
kinesin family member 20A
chr13_-_99667960 0.459 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr19_-_46526304 0.451 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr12_-_49351228 0.450 ENST00000541959.1
ENST00000447318.2
ARF3

ADP-ribosylation factor 3

chr11_-_85779971 0.446 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr12_+_57853918 0.417 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1



GLI family zinc finger 1



chr17_+_76210267 0.413 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5



baculoviral IAP repeat containing 5



chr5_+_113697983 0.401 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr12_+_22778291 0.400 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr10_-_75226166 0.395 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr6_+_36646435 0.389 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
CDKN1A


cyclin-dependent kinase inhibitor 1A (p21, Cip1)


chr17_-_43209862 0.389 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr17_+_39975544 0.388 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr2_-_216003127 0.387 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chrX_+_56259316 0.384 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr11_+_18477369 0.380 ENST00000396213.3
ENST00000280706.2
LDHAL6A

lactate dehydrogenase A-like 6A

chr12_-_8815215 0.377 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr17_+_40704938 0.376 ENST00000225929.5
HSD17B1
hydroxysteroid (17-beta) dehydrogenase 1
chr17_+_39975455 0.375 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr5_-_9630463 0.374 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr12_-_8815299 0.363 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr12_+_65672702 0.362 ENST00000538045.1
ENST00000535239.1
MSRB3

methionine sulfoxide reductase B3

chr2_-_208030647 0.361 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_+_21467414 0.355 ENST00000554422.1
ENST00000298681.4
SLC39A2

solute carrier family 39 (zinc transporter), member 2

chr11_-_7818520 0.352 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chrX_+_70443050 0.352 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr4_+_156680518 0.348 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr6_+_121756809 0.344 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr7_-_27142290 0.342 ENST00000222718.5
HOXA2
homeobox A2
chr1_+_153950202 0.339 ENST00000608236.1
RP11-422P24.11
RP11-422P24.11
chr14_+_55033815 0.338 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr15_+_60296421 0.337 ENST00000396057.4
FOXB1
forkhead box B1
chr17_+_76210367 0.336 ENST00000592734.1
ENST00000587746.1
BIRC5

baculoviral IAP repeat containing 5

chr17_-_46657473 0.333 ENST00000332503.5
HOXB4
homeobox B4
chr12_-_13529642 0.333 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr11_-_62752162 0.332 ENST00000458333.2
ENST00000421062.2
SLC22A6

solute carrier family 22 (organic anion transporter), member 6

chr12_+_18891045 0.331 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr2_-_40680578 0.330 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr20_-_22565101 0.329 ENST00000419308.2
FOXA2
forkhead box A2
chrX_+_16804544 0.329 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr19_+_54926621 0.328 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1



tweety family member 1



chr6_+_43739697 0.323 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr11_-_28129656 0.322 ENST00000263181.6
KIF18A
kinesin family member 18A
chrX_+_135230712 0.322 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr2_-_27718052 0.322 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr9_+_124461603 0.315 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr19_+_54926601 0.315 ENST00000301194.4
TTYH1
tweety family member 1
chr17_-_39222131 0.312 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr4_+_166248775 0.312 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1



methylsterol monooxygenase 1



chr20_+_43343476 0.304 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr16_+_3162557 0.303 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205



zinc finger protein 205



chr5_+_54320078 0.302 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr4_+_156680143 0.299 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr2_+_62932779 0.293 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1


EH domain binding protein 1


chr6_-_40555176 0.292 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr2_+_201994208 0.289 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chrX_-_131623874 0.287 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr20_+_43343517 0.287 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr1_+_28586006 0.287 ENST00000253063.3
SESN2
sestrin 2
chr12_-_7848364 0.283 ENST00000329913.3
GDF3
growth differentiation factor 3
chr9_+_75766763 0.283 ENST00000456643.1
ENST00000415424.1
ANXA1

annexin A1

chr1_-_182641367 0.283 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr12_+_104324112 0.282 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr17_-_34122596 0.279 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr20_+_43343886 0.275 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr2_+_176972000 0.275 ENST00000249504.5
HOXD11
homeobox D11
chr3_+_4535155 0.274 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr7_+_2687173 0.273 ENST00000403167.1
TTYH3
tweety family member 3
chr7_-_99527243 0.268 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr17_+_7210294 0.268 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chr3_+_38206975 0.267 ENST00000446845.1
ENST00000311806.3
OXSR1

oxidative stress responsive 1

chr2_+_62933001 0.264 ENST00000263991.5
ENST00000354487.3
EHBP1

EH domain binding protein 1

chr4_+_156680153 0.263 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3




guanylate cyclase 1, soluble, beta 3




chr19_-_11689752 0.261 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5



acid phosphatase 5, tartrate resistant



chrX_+_101380642 0.259 ENST00000372780.1
ENST00000329035.2
TCEAL2

transcription elongation factor A (SII)-like 2

chr12_+_21525818 0.259 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP


islet amyloid polypeptide


chrX_+_15808569 0.258 ENST00000380308.3
ENST00000307771.7
ZRSR2

zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

chr19_-_36001286 0.257 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN














dermokine














chr6_-_131321863 0.254 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chrX_-_109561294 0.251 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr5_+_137514834 0.250 ENST00000508792.1
ENST00000504621.1
KIF20A

kinesin family member 20A

chr8_+_73449625 0.250 ENST00000523207.1
KCNB2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr22_+_40441456 0.246 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr14_+_55034599 0.244 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr4_-_170924888 0.242 ENST00000502832.1
ENST00000393704.3
MFAP3L

microfibrillar-associated protein 3-like

chr19_-_14217672 0.242 ENST00000587372.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr4_-_69111401 0.241 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr13_+_109248500 0.239 ENST00000356711.2
MYO16
myosin XVI
chr21_-_46962379 0.239 ENST00000311124.4
ENST00000380010.4
SLC19A1

solute carrier family 19 (folate transporter), member 1

chr1_+_202995611 0.238 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr21_-_31869451 0.236 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr17_+_38497640 0.235 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr12_-_48152853 0.235 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_10452929 0.233 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2


myosin, heavy chain 2, skeletal muscle, adult


chr1_+_154975258 0.232 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr6_+_45390222 0.229 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr3_+_52811596 0.227 ENST00000542827.1
ENST00000273283.2
ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

chr19_-_42916499 0.225 ENST00000601189.1
ENST00000599211.1
LIPE

lipase, hormone-sensitive

chr14_+_55034330 0.224 ENST00000251091.5
SAMD4A
sterile alpha motif domain containing 4A
chr3_+_10857885 0.223 ENST00000254488.2
ENST00000454147.1
SLC6A11

solute carrier family 6 (neurotransmitter transporter), member 11

chr15_+_76016293 0.222 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr14_-_55658323 0.220 ENST00000554067.1
ENST00000247191.2
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr19_-_36001113 0.219 ENST00000434389.1
DMKN
dermokine
chr12_-_48152611 0.217 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr8_+_11660227 0.214 ENST00000443614.2
ENST00000525900.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr19_-_39390350 0.213 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2


sirtuin 2


chr1_-_226374373 0.212 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr11_-_6426635 0.209 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1


amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)


chr12_-_49351303 0.208 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr6_-_10419871 0.206 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_+_39390320 0.204 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr10_-_126432821 0.204 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chrX_-_106146547 0.201 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr11_+_61447845 0.201 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chrX_+_122318113 0.201 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr1_+_154377669 0.201 ENST00000368485.3
ENST00000344086.4
IL6R

interleukin 6 receptor

chr14_-_55658252 0.200 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr12_-_110011288 0.200 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr5_-_137674000 0.199 ENST00000510119.1
ENST00000513970.1
CDC25C

cell division cycle 25C

chrX_-_128788914 0.197 ENST00000429967.1
ENST00000307484.6
APLN

apelin

chr15_+_41549105 0.196 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr2_+_219081817 0.196 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2


actin related protein 2/3 complex, subunit 2, 34kDa


chr15_+_63481668 0.195 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B


RAB8B, member RAS oncogene family


chr19_+_45973120 0.194 ENST00000592811.1
ENST00000586615.1
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_-_94079648 0.194 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chrX_+_123480375 0.192 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr12_-_85306594 0.190 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr1_-_19229248 0.188 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr12_-_48152428 0.188 ENST00000449771.2
ENST00000395358.3
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr11_+_120081475 0.188 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr4_+_57371509 0.187 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr2_+_201994042 0.187 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_8378140 0.186 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr1_-_19229014 0.186 ENST00000538839.1
ENST00000290597.5
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr15_+_90319557 0.186 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr1_+_160051319 0.185 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr4_+_102268904 0.180 ENST00000527564.1
ENST00000529296.1
AP001816.1

Uncharacterized protein

chrX_+_122318006 0.180 ENST00000371266.1
ENST00000264357.5
GRIA3

glutamate receptor, ionotropic, AMPA 3

chr1_+_41445413 0.180 ENST00000541520.1
CTPS1
CTP synthase 1
chr11_-_107590383 0.180 ENST00000525934.1
ENST00000531293.1
SLN

sarcolipin

chr20_-_1309809 0.179 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr20_+_825275 0.178 ENST00000541082.1
FAM110A
family with sequence similarity 110, member A
chr17_+_38474489 0.177 ENST00000394089.2
ENST00000425707.3
RARA

retinoic acid receptor, alpha

chr1_-_15735925 0.177 ENST00000427824.1
RP3-467K16.4
RP3-467K16.4
chr19_-_46418033 0.176 ENST00000341294.2
NANOS2
nanos homolog 2 (Drosophila)
chr7_+_99724317 0.176 ENST00000398075.2
ENST00000421390.1
MBLAC1

metallo-beta-lactamase domain containing 1

chr5_+_150040403 0.176 ENST00000517768.1
ENST00000297130.4
MYOZ3

myozenin 3

chr12_-_18890940 0.176 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1





phospholipase C, zeta 1





chr3_+_127770455 0.174 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr1_-_150780757 0.174 ENST00000271651.3
CTSK
cathepsin K
chr11_-_66104237 0.174 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr16_-_67965756 0.173 ENST00000571044.1
ENST00000571605.1
CTRL

chymotrypsin-like

chr11_+_28129795 0.172 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr4_-_186456652 0.171 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr8_+_102504651 0.169 ENST00000251808.3
ENST00000521085.1
GRHL2

grainyhead-like 2 (Drosophila)

chr12_-_120554534 0.169 ENST00000538903.1
ENST00000534951.1
RAB35

RAB35, member RAS oncogene family

chr1_-_28969517 0.168 ENST00000263974.4
ENST00000373824.4
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr16_+_88704978 0.168 ENST00000244241.4
IL17C
interleukin 17C
chr10_-_131762105 0.167 ENST00000368648.3
ENST00000355311.5
EBF3

early B-cell factor 3

chr2_-_219031709 0.166 ENST00000295683.2
CXCR1
chemokine (C-X-C motif) receptor 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.3 0.8 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.6 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.8 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 1.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.2 0.6 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 0.9 GO:0035803 egg coat formation(GO:0035803)
0.2 0.5 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.1 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.4 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.4 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.5 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.3 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.3 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.9 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.1 GO:0021603 cranial nerve formation(GO:0021603)
0.1 0.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.5 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.4 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.4 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.2 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.3 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.2 GO:2000612 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 1.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) chemical homeostasis within a tissue(GO:0048875)
0.0 3.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0015820 leucine transport(GO:0015820)
0.0 0.1 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 1.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.0 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0072255 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.5 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.4 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 1.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.0 GO:0060067 cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0060215 primitive hemopoiesis(GO:0060215) regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.0 GO:0003129 heart induction(GO:0003129)
0.0 0.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.0 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 1.0 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.9 GO:0043219 lateral loop(GO:0043219)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 4.7 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 0.5 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 0.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 1.0 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.4 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.8 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.8 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 2.1 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors