Motif ID: STAT6

Z-value: 0.740


Transcription factors associated with STAT6:

Gene SymbolEntrez IDGene Name
STAT6 ENSG00000166888.6 STAT6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT6hg19_v2_chr12_-_57505121_575052160.262.2e-01Click!


Activity profile for motif STAT6.

activity profile for motif STAT6


Sorted Z-values histogram for motif STAT6

Sorted Z-values for motif STAT6



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_205391178 6.731 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chrX_+_135251783 2.323 ENST00000394153.2
FHL1
four and a half LIM domains 1
chrX_+_135252050 2.096 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chrX_+_135251835 2.080 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr2_+_113885138 1.944 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr10_+_102106829 1.798 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr11_-_128457446 1.519 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr2_-_31440377 1.432 ENST00000444918.2
ENST00000403897.3
CAPN14

calpain 14

chr4_+_54966198 1.206 ENST00000326902.2
ENST00000503800.1
GSX2

GS homeobox 2

chr9_+_36572851 1.161 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr1_-_160616804 1.158 ENST00000538290.1
SLAMF1
signaling lymphocytic activation molecule family member 1
chr17_-_17740325 1.141 ENST00000338854.5
SREBF1
sterol regulatory element binding transcription factor 1
chr8_+_49984894 1.122 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
C8orf22


chromosome 8 open reading frame 22


chr22_+_44464923 1.113 ENST00000404989.1
PARVB
parvin, beta
chrX_-_106960285 1.029 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr14_+_55034599 0.980 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr2_-_190044480 0.980 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_+_65082289 0.968 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr12_+_9144626 0.948 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_+_76745385 0.921 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
B3GNT6


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)


chr1_-_76398077 0.908 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chr19_+_38924316 0.863 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1


ryanodine receptor 1 (skeletal)


chr16_+_30075463 0.797 ENST00000562168.1
ENST00000569545.1
ALDOA

aldolase A, fructose-bisphosphate

chr1_-_8086343 0.744 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1


ERBB receptor feedback inhibitor 1


chr17_-_17740287 0.735 ENST00000355815.4
ENST00000261646.5
SREBF1

sterol regulatory element binding transcription factor 1

chr18_-_24445664 0.710 ENST00000578776.1
AQP4
aquaporin 4
chr8_+_11666649 0.707 ENST00000528643.1
ENST00000525777.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr12_+_6493319 0.704 ENST00000536876.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr2_+_182756915 0.700 ENST00000428267.2
SSFA2
sperm specific antigen 2
chr2_+_191792376 0.687 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr16_+_30075595 0.673 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr17_-_39507064 0.670 ENST00000007735.3
KRT33A
keratin 33A
chr3_+_140981456 0.662 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr11_-_67981046 0.653 ENST00000402789.1
ENST00000402185.2
ENST00000458496.1
SUV420H1


suppressor of variegation 4-20 homolog 1 (Drosophila)


chr1_+_150245099 0.650 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr1_-_41328018 0.647 ENST00000372638.2
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr14_-_69446034 0.642 ENST00000193403.6
ACTN1
actinin, alpha 1
chr1_-_241803679 0.633 ENST00000331838.5
OPN3
opsin 3
chr16_+_30075783 0.623 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr6_+_30525051 0.620 ENST00000376557.3
PRR3
proline rich 3
chr1_-_209824643 0.617 ENST00000391911.1
ENST00000415782.1
LAMB3

laminin, beta 3

chr6_-_27880174 0.603 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr15_+_89402148 0.601 ENST00000560601.1
ACAN
aggrecan
chr2_+_219745020 0.593 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr6_-_30524951 0.575 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr3_-_10149907 0.545 ENST00000450660.2
ENST00000524279.1
FANCD2OS

FANCD2 opposite strand

chr3_-_73673991 0.542 ENST00000308537.4
ENST00000263666.4
PDZRN3

PDZ domain containing ring finger 3

chr1_+_150245177 0.534 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr2_+_68961934 0.533 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr11_+_112832133 0.531 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr19_+_2785458 0.531 ENST00000307741.6
ENST00000585338.1
THOP1

thimet oligopeptidase 1

chr3_-_98235962 0.521 ENST00000513873.1
CLDND1
claudin domain containing 1
chr2_+_173600514 0.515 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_68961905 0.515 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr3_+_189507523 0.511 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr2_+_173600565 0.503 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_120988229 0.498 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr6_-_117150198 0.479 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A


G protein-coupled receptor, family C, group 6, member A


chr4_+_72897521 0.460 ENST00000308744.6
ENST00000344413.5
NPFFR2

neuropeptide FF receptor 2

chr3_+_158787041 0.460 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr12_-_71031220 0.457 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_-_131486367 0.435 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12




zinc finger, DHHC-type containing 12




chr8_-_42623747 0.433 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr3_+_189507432 0.431 ENST00000354600.5
TP63
tumor protein p63
chr2_-_204400113 0.429 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr11_-_14379997 0.418 ENST00000526063.1
ENST00000532814.1
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr8_-_42623924 0.418 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr12_-_54779511 0.415 ENST00000551109.1
ENST00000546970.1
ZNF385A

zinc finger protein 385A

chr9_-_14910990 0.412 ENST00000380881.4
ENST00000422223.2
FREM1

FRAS1 related extracellular matrix 1

chr19_-_54604083 0.409 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR





osteoclast associated, immunoglobulin-like receptor





chr1_+_214163033 0.405 ENST00000607425.1
PROX1
prospero homeobox 1
chr12_-_71031185 0.400 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr2_-_134326009 0.393 ENST00000409261.1
ENST00000409213.1
NCKAP5

NCK-associated protein 5

chr6_-_41254403 0.388 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1



triggering receptor expressed on myeloid cells 1



chr18_-_24445729 0.387 ENST00000383168.4
AQP4
aquaporin 4
chr1_+_32608566 0.377 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr5_+_74011328 0.376 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr16_-_29757272 0.375 ENST00000329410.3
C16orf54
chromosome 16 open reading frame 54
chr17_+_7384721 0.374 ENST00000412468.2
SLC35G6
solute carrier family 35, member G6
chr11_-_60719213 0.373 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr3_+_158991025 0.372 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chrX_-_138914394 0.365 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C



ATPase, class VI, type 11C



chr2_+_202316392 0.361 ENST00000194530.3
ENST00000392249.2
STRADB

STE20-related kinase adaptor beta

chr2_+_182756615 0.356 ENST00000431877.2
ENST00000320370.7
SSFA2

sperm specific antigen 2

chr5_+_126984710 0.352 ENST00000379445.3
CTXN3
cortexin 3
chr15_+_91643442 0.346 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr12_-_82152444 0.343 ENST00000549325.1
ENST00000550584.2
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr6_+_38690622 0.340 ENST00000327475.6
DNAH8
dynein, axonemal, heavy chain 8
chr1_+_26759295 0.338 ENST00000430232.1
DHDDS
dehydrodolichyl diphosphate synthase
chr3_-_57233966 0.333 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr20_+_58251716 0.330 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr1_-_205649580 0.330 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr1_-_68299130 0.328 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr2_+_197504278 0.309 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150



coiled-coil domain containing 150



chr7_+_129015484 0.294 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr8_+_9953214 0.292 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr1_-_179834311 0.276 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr1_+_12123414 0.267 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr3_+_35682913 0.259 ENST00000449196.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr8_+_9953061 0.258 ENST00000522907.1
ENST00000528246.1
MSRA

methionine sulfoxide reductase A

chr22_+_38201114 0.255 ENST00000340857.2
H1F0
H1 histone family, member 0
chr12_-_82152420 0.255 ENST00000552948.1
ENST00000548586.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr14_-_37642016 0.254 ENST00000331299.5
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr12_-_53097247 0.253 ENST00000341809.3
ENST00000537195.1
KRT77

keratin 77

chr7_+_112120908 0.251 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1


leucine-rich single-pass membrane protein 1


chr6_-_41168920 0.248 ENST00000483722.1
TREML2
triggering receptor expressed on myeloid cells-like 2
chr10_-_24770632 0.248 ENST00000596413.1
AL353583.1
AL353583.1
chr11_-_58980342 0.245 ENST00000361050.3
MPEG1
macrophage expressed 1
chr2_+_131769256 0.244 ENST00000355771.3
ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
chr15_+_67841330 0.231 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr9_-_3469181 0.230 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr11_+_65101225 0.223 ENST00000528416.1
ENST00000415073.2
ENST00000252268.4
DPF2


D4, zinc and double PHD fingers family 2


chr16_-_67753206 0.222 ENST00000268797.7
GFOD2
glucose-fructose oxidoreductase domain containing 2
chr1_+_202431859 0.221 ENST00000391959.3
ENST00000367270.4
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr6_+_116850174 0.220 ENST00000416171.2
ENST00000368597.2
ENST00000452373.1
ENST00000405399.1
FAM26D



family with sequence similarity 26, member D



chr4_+_166300084 0.218 ENST00000402744.4
CPE
carboxypeptidase E
chr7_-_76829125 0.211 ENST00000248598.5
FGL2
fibrinogen-like 2
chr9_-_111619239 0.211 ENST00000374667.3
ACTL7B
actin-like 7B
chr8_-_82359662 0.209 ENST00000519260.1
ENST00000256103.2
PMP2

peripheral myelin protein 2

chr5_+_138609441 0.208 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3


matrin 3


chr12_+_44152740 0.206 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4




interleukin-1 receptor-associated kinase 4




chr15_+_85525205 0.205 ENST00000394553.1
ENST00000339708.5
PDE8A

phosphodiesterase 8A

chr6_-_11232891 0.203 ENST00000379433.5
ENST00000379446.5
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr4_-_116034979 0.201 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr2_-_16804320 0.196 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr11_-_8964580 0.184 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr11_+_112832090 0.184 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr12_+_56435637 0.182 ENST00000356464.5
ENST00000552361.1
RPS26

ribosomal protein S26

chr2_-_203735484 0.181 ENST00000420558.1
ENST00000418208.1
ICA1L

islet cell autoantigen 1,69kDa-like

chr9_+_131464767 0.179 ENST00000291906.4
PKN3
protein kinase N3
chr14_+_38677123 0.179 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr1_+_42619070 0.177 ENST00000372581.1
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr6_-_32821599 0.174 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_122840015 0.169 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chrX_+_102192200 0.168 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chrX_-_50386648 0.167 ENST00000460112.3
SHROOM4
shroom family member 4
chr8_+_97506033 0.165 ENST00000518385.1
SDC2
syndecan 2
chr12_-_82153087 0.165 ENST00000547623.1
ENST00000549396.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr15_-_23932437 0.163 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr16_-_67694597 0.160 ENST00000393919.4
ENST00000219251.8
ACD

adrenocortical dysplasia homolog (mouse)

chr9_-_135996537 0.160 ENST00000372050.3
ENST00000372047.3
RALGDS

ral guanine nucleotide dissociation stimulator

chr12_+_80730292 0.158 ENST00000298820.3
OTOGL
otogelin-like
chr17_-_62308087 0.157 ENST00000583097.1
TEX2
testis expressed 2
chr14_-_46185155 0.156 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr10_+_98064085 0.155 ENST00000419175.1
ENST00000371174.2
DNTT

DNA nucleotidylexotransferase

chr9_-_100000957 0.153 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5

RP11-498P14.5

chr1_-_108735440 0.150 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_+_121311966 0.149 ENST00000338040.4
FBXO40
F-box protein 40
chr3_+_51575596 0.144 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr6_+_84222220 0.139 ENST00000369700.3
PRSS35
protease, serine, 35
chr12_+_52281744 0.135 ENST00000301190.6
ENST00000538991.1
ANKRD33

ankyrin repeat domain 33

chr1_+_152691998 0.134 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr12_+_52282001 0.130 ENST00000340970.4
ANKRD33
ankyrin repeat domain 33
chr17_+_7461613 0.127 ENST00000438470.1
ENST00000436057.1
TNFSF13

tumor necrosis factor (ligand) superfamily, member 13

chr13_-_74708372 0.125 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr20_+_42136308 0.124 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1



l(3)mbt-like 1 (Drosophila)



chr20_+_57209828 0.123 ENST00000598340.1
MGC4294
HCG1785561; MGC4294 protein; Uncharacterized protein
chr2_+_103378472 0.121 ENST00000412401.2
TMEM182
transmembrane protein 182
chr12_-_6451235 0.119 ENST00000440083.2
ENST00000162749.2
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr21_+_17792672 0.119 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr8_-_117886955 0.116 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr9_+_90112590 0.113 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chrX_-_100546314 0.108 ENST00000356784.1
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr2_+_234686976 0.101 ENST00000389758.3
MROH2A
maestro heat-like repeat family member 2A
chr20_+_42574317 0.096 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr11_+_63655987 0.081 ENST00000509502.2
ENST00000512060.1
MARK2

MAP/microtubule affinity-regulating kinase 2

chr19_+_13229126 0.080 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr15_+_25200074 0.074 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN



small nuclear ribonucleoprotein polypeptide N



chr1_+_89246647 0.071 ENST00000544045.1
PKN2
protein kinase N2
chr9_+_90112117 0.066 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr4_+_71337834 0.061 ENST00000304887.5
MUC7
mucin 7, secreted
chr12_+_6493199 0.060 ENST00000228918.4
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr22_-_29457832 0.059 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr10_-_61122220 0.057 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C






family with sequence similarity 13, member C






chr2_-_204400013 0.054 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
RAPH1




Ras association (RalGDS/AF-6) and pleckstrin homology domains 1




chr19_+_15052301 0.052 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr1_-_173572181 0.051 ENST00000536496.1
ENST00000367714.3
SLC9C2

solute carrier family 9, member C2 (putative)

chr8_+_104311059 0.049 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
FZD6


frizzled family receptor 6


chrX_-_139866723 0.048 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr7_-_15726296 0.045 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr14_-_24553834 0.044 ENST00000397002.2
NRL
neural retina leucine zipper
chr5_+_150051149 0.044 ENST00000523553.1
MYOZ3
myozenin 3
chr12_+_6493406 0.038 ENST00000543190.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr9_+_90112741 0.037 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr16_+_69984810 0.036 ENST00000393701.2
ENST00000568461.1
CLEC18A

C-type lectin domain family 18, member A

chr3_+_141121164 0.036 ENST00000510338.1
ENST00000504673.1
ZBTB38

zinc finger and BTB domain containing 38

chr17_+_7461849 0.031 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_-_88119580 0.027 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr14_+_22520762 0.025 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr18_-_51107372 0.024 ENST00000565170.1
RP11-202D1.2
RP11-202D1.2
chr17_+_7461781 0.024 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7462031 0.023 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_+_147258266 0.023 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr14_-_24551137 0.022 ENST00000396995.1
NRL
neural retina leucine zipper
chr3_-_185655795 0.022 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B


transformer 2 beta homolog (Drosophila)


chr1_+_78383813 0.019 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr17_+_34538310 0.019 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1











chemokine (C-C motif) ligand 4-like 1











chr15_+_64386261 0.018 ENST00000560829.1
SNX1
sorting nexin 1
chr17_+_7461580 0.017 ENST00000483039.1
ENST00000396542.1
TNFSF13

tumor necrosis factor (ligand) superfamily, member 13

chrX_+_100878079 0.017 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 1.2 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 1.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.5 GO:0030578 PML body organization(GO:0030578)
0.2 0.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.9 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.7 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 1.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 1.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 2.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.3 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 6.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.3 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.4 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.7 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.4 GO:0007619 courtship behavior(GO:0007619)
0.1 1.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.4 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.6 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.0 0.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0006833 water transport(GO:0006833)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.9 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.5 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.2 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.4 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.9 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 2.1 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 1.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 8.2 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 1.9 GO:0032810 sterol response element binding(GO:0032810)
0.4 1.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 0.9 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.2 0.9 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 2.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.7 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 1.0 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.0 GO:0043426 MRF binding(GO:0043426)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 7.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.1 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 3.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.0 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.9 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 1.0 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME_OPSINS Genes involved in Opsins
0.0 2.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 2.1 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.4 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta