Motif ID: SPIC

Z-value: 0.994


Transcription factors associated with SPIC:

Gene SymbolEntrez IDGene Name
SPIC ENSG00000166211.6 SPIC

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SPIChg19_v2_chr12_+_101869096_1018691990.135.4e-01Click!


Activity profile for motif SPIC.

activity profile for motif SPIC


Sorted Z-values histogram for motif SPIC

Sorted Z-values for motif SPIC



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_8201091 4.750 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1



chr19_-_51471362 3.440 ENST00000376853.4
ENST00000424910.2
KLK6

kallikrein-related peptidase 6

chr19_-_51471381 3.368 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr12_+_15699286 2.985 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr2_-_113594279 2.593 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr12_+_8975061 2.462 ENST00000299698.7
A2ML1
alpha-2-macroglobulin-like 1
chr4_-_80994471 2.382 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr3_-_111314230 2.311 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr18_-_33077556 2.218 ENST00000589273.1
ENST00000586489.1
INO80C

INO80 complex subunit C

chr2_+_113885138 2.062 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr5_+_33936491 2.056 ENST00000330120.3
RXFP3
relaxin/insulin-like family peptide receptor 3
chr4_-_57547454 2.053 ENST00000556376.2
HOPX
HOP homeobox
chr2_+_233925064 2.050 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr19_+_35645618 2.039 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5






FXYD domain containing ion transport regulator 5






chr19_-_15344243 1.994 ENST00000602233.1
EPHX3
epoxide hydrolase 3
chr19_-_51456344 1.942 ENST00000336334.3
ENST00000593428.1
KLK5

kallikrein-related peptidase 5

chr19_-_51456321 1.919 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr15_-_80263506 1.910 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr4_-_80994619 1.856 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr1_-_43855444 1.772 ENST00000372455.4
MED8
mediator complex subunit 8
chr19_-_51456198 1.756 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr4_-_111119804 1.755 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr12_+_1800179 1.737 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr19_+_35645817 1.653 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr1_+_120839412 1.648 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr1_+_151030234 1.582 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_203651937 1.519 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr19_-_42927251 1.439 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr1_-_27816556 1.434 ENST00000536657.1
WASF2
WAS protein family, member 2
chr1_+_206138884 1.432 ENST00000341209.5
ENST00000607379.1
FAM72A

family with sequence similarity 72, member A

chr16_+_23652773 1.416 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
DCTN5


dynactin 5 (p25)


chr10_+_102106829 1.405 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr1_-_143913143 1.398 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr2_-_69098566 1.383 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr7_+_74188309 1.378 ENST00000289473.4
ENST00000433458.1
NCF1

neutrophil cytosolic factor 1

chr1_+_206138457 1.375 ENST00000367128.3
ENST00000431655.2
FAM72A

family with sequence similarity 72, member A

chr22_-_37880543 1.353 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_-_95640218 1.347 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484


zinc finger protein 484


chr1_+_120839005 1.332 ENST00000369390.3
ENST00000452190.1
FAM72B

family with sequence similarity 72, member B

chr5_+_96211643 1.299 ENST00000437043.3
ENST00000510373.1
ERAP2

endoplasmic reticulum aminopeptidase 2

chr12_+_120105558 1.261 ENST00000229328.5
ENST00000541640.1
PRKAB1

protein kinase, AMP-activated, beta 1 non-catalytic subunit

chr1_+_192127578 1.252 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr6_+_106534192 1.251 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr2_-_238323007 1.245 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr18_-_33077942 1.239 ENST00000334598.7
INO80C
INO80 complex subunit C
chr16_+_30194916 1.220 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A


coronin, actin binding protein, 1A


chr10_-_98031265 1.200 ENST00000224337.5
ENST00000371176.2
BLNK

B-cell linker

chr5_-_39270725 1.199 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chrX_-_107018969 1.180 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr11_+_68671310 1.154 ENST00000255078.3
ENST00000539224.1
IGHMBP2

immunoglobulin mu binding protein 2

chr1_-_6420737 1.139 ENST00000541130.1
ENST00000377845.3
ACOT7

acyl-CoA thioesterase 7

chr3_+_47324424 1.122 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr15_+_63354769 1.111 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr11_-_64647144 1.090 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EHD1


EH-domain containing 1


chr16_+_11439286 1.085 ENST00000312499.5
ENST00000576027.1
RMI2

RecQ mediated genome instability 2

chr1_-_154946825 1.083 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr8_-_144655141 1.072 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr15_+_90744533 1.066 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_-_64851496 1.050 ENST00000404147.3
ENST00000275517.3
CDCA5

cell division cycle associated 5

chr16_-_88851618 1.036 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr3_+_130613226 1.030 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1




ATPase, Ca++ transporting, type 2C, member 1




chr10_-_121302195 1.023 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr10_-_98031310 1.003 ENST00000427367.2
ENST00000413476.2
BLNK

B-cell linker

chr1_+_24645807 0.990 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr12_-_51785182 0.976 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6



UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)



chr5_+_154393260 0.967 ENST00000435029.4
KIF4B
kinesin family member 4B
chr10_-_75401500 0.963 ENST00000359322.4
MYOZ1
myozenin 1
chr17_+_1959369 0.951 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr9_+_116037922 0.945 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr15_-_33360342 0.944 ENST00000558197.1
FMN1
formin 1
chr16_-_20702578 0.942 ENST00000307493.4
ENST00000219151.4
ACSM1

acyl-CoA synthetase medium-chain family member 1

chr1_+_110091189 0.939 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr17_-_37009882 0.935 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23




ribosomal protein L23




chr1_+_150245177 0.918 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr20_-_54967187 0.915 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA













aurora kinase A













chr3_+_121796697 0.911 ENST00000482356.1
ENST00000393627.2
CD86

CD86 molecule

chr4_-_159094194 0.905 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B


family with sequence similarity 198, member B


chr11_-_1643368 0.902 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr2_+_48667983 0.899 ENST00000449090.2
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr1_+_169337172 0.895 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1



basic leucine zipper nuclear factor 1



chr3_+_130569592 0.894 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_-_150780757 0.885 ENST00000271651.3
CTSK
cathepsin K
chr1_+_24645865 0.878 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_24127256 0.876 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr1_+_150245099 0.869 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr1_-_109618566 0.865 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr20_+_814377 0.862 ENST00000304189.2
ENST00000381939.1
FAM110A

family with sequence similarity 110, member A

chr1_+_11994715 0.845 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1



procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1



chr4_-_80994210 0.843 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr11_+_70244510 0.832 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
CTTN


cortactin


chr19_+_19496728 0.826 ENST00000537887.1
ENST00000417582.2
GATAD2A

GATA zinc finger domain containing 2A

chr16_+_30205225 0.823 ENST00000345535.4
ENST00000251303.6
SLX1A

SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

chrX_-_51239425 0.823 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr17_-_43487741 0.818 ENST00000455881.1
ARHGAP27
Rho GTPase activating protein 27
chr11_+_133938820 0.816 ENST00000299106.4
ENST00000529443.2
JAM3

junctional adhesion molecule 3

chr1_-_52499443 0.816 ENST00000371614.1
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr1_-_47069886 0.812 ENST00000371946.4
ENST00000371945.4
ENST00000428112.2
ENST00000529170.1
MKNK1



MAP kinase interacting serine/threonine kinase 1



chr15_-_34610962 0.812 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr12_-_49351228 0.809 ENST00000541959.1
ENST00000447318.2
ARF3

ADP-ribosylation factor 3

chr16_-_29465668 0.809 ENST00000569622.1
RP11-345J4.5
BolA-like protein 2
chr16_+_29465822 0.805 ENST00000330181.5
ENST00000351581.4
SLX1B

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr17_+_48450575 0.795 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1


essential meiotic structure-specific endonuclease 1


chr1_+_22979474 0.788 ENST00000509305.1
C1QB
complement component 1, q subcomponent, B chain
chr10_+_112257596 0.787 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr4_-_99064387 0.786 ENST00000295268.3
STPG2
sperm-tail PG-rich repeat containing 2
chr12_-_7596735 0.783 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1


CD163 molecule-like 1


chr1_-_180991978 0.781 ENST00000542060.1
ENST00000258301.5
STX6

syntaxin 6

chr12_-_54778471 0.770 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A


zinc finger protein 385A


chr2_+_48667898 0.769 ENST00000281394.4
ENST00000294952.8
PPP1R21

protein phosphatase 1, regulatory subunit 21

chr1_-_47069955 0.769 ENST00000341183.5
ENST00000496619.1
MKNK1

MAP kinase interacting serine/threonine kinase 1

chr9_-_134145880 0.769 ENST00000372269.3
ENST00000464831.1
FAM78A

family with sequence similarity 78, member A

chrX_+_24072833 0.755 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr3_+_52321827 0.751 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK




glycerate kinase




chr2_+_37458928 0.748 ENST00000439218.1
ENST00000432075.1
NDUFAF7

NADH dehydrogenase (ubiquinone) complex I, assembly factor 7

chr12_+_53693466 0.744 ENST00000267103.5
ENST00000548632.1
C12orf10

chromosome 12 open reading frame 10

chr1_+_212208919 0.741 ENST00000366991.4
ENST00000542077.1
DTL

denticleless E3 ubiquitin protein ligase homolog (Drosophila)

chr11_-_102668879 0.731 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr3_-_28390120 0.721 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr12_-_113841678 0.718 ENST00000552280.1
ENST00000257549.4
SDS

serine dehydratase

chr13_+_31309645 0.714 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr10_-_75676400 0.703 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr19_+_41256764 0.700 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA



small nuclear ribonucleoprotein polypeptide A



chr12_-_77272765 0.698 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2



cysteine and glycine-rich protein 2



chr14_-_69445968 0.693 ENST00000438964.2
ACTN1
actinin, alpha 1
chr11_-_67120974 0.692 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr6_-_32145861 0.687 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr14_+_67291158 0.687 ENST00000555456.1
GPHN
gephyrin
chr18_-_33077868 0.687 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80C



RP11-322E11.6
INO80 complex subunit C



Uncharacterized protein
chr11_+_72983246 0.677 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr12_+_10658489 0.667 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr8_-_42623747 0.666 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr14_-_69446034 0.656 ENST00000193403.6
ACTN1
actinin, alpha 1
chr5_+_110074685 0.649 ENST00000355943.3
ENST00000447245.2
SLC25A46

solute carrier family 25, member 46

chr4_-_99578776 0.646 ENST00000515287.1
TSPAN5
tetraspanin 5
chr14_-_69445793 0.644 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr6_-_136571400 0.644 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2


mitochondrial fission regulator 2


chr8_-_8243968 0.643 ENST00000520004.1
SGK223
Tyrosine-protein kinase SgK223
chr19_+_38826477 0.639 ENST00000409410.2
ENST00000215069.4
CATSPERG

catsper channel auxiliary subunit gamma

chrX_+_51075658 0.635 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr5_+_115177178 0.631 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chrX_+_100075368 0.631 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
CSTF2


cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa


chr17_+_7482785 0.630 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68


CD68 molecule


chr19_+_45417504 0.629 ENST00000588750.1
ENST00000588802.1
APOC1

apolipoprotein C-I

chr8_-_42623924 0.625 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr22_+_37309662 0.625 ENST00000403662.3
ENST00000262825.5
CSF2RB

colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

chr12_-_95044309 0.624 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr3_-_28390298 0.623 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr4_-_74853897 0.617 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr1_+_22979676 0.617 ENST00000432749.2
ENST00000314933.6
C1QB

complement component 1, q subcomponent, B chain

chr20_+_3869423 0.616 ENST00000497424.1
PANK2
pantothenate kinase 2
chr3_-_138665969 0.614 ENST00000330315.3
FOXL2
forkhead box L2
chr3_-_196014520 0.614 ENST00000441879.1
ENST00000292823.2
ENST00000411591.1
ENST00000431016.1
ENST00000443555.1
PCYT1A




phosphate cytidylyltransferase 1, choline, alpha




chr1_-_24126892 0.612 ENST00000374497.3
ENST00000425913.1
GALE

UDP-galactose-4-epimerase

chr2_-_70780572 0.611 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr19_+_1752372 0.611 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr7_-_99698338 0.610 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr5_-_140013275 0.609 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14


CD14 molecule


chr3_-_156272924 0.605 ENST00000467789.1
ENST00000265044.2
SSR3

signal sequence receptor, gamma (translocon-associated protein gamma)

chrX_+_30233668 0.603 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr15_-_67546963 0.602 ENST00000561452.1
ENST00000261880.5
AAGAB

alpha- and gamma-adaptin binding protein

chr13_+_41363581 0.595 ENST00000338625.4
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chrX_-_153637612 0.595 ENST00000369807.1
ENST00000369808.3
DNASE1L1

deoxyribonuclease I-like 1

chr5_-_159797627 0.594 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr12_-_109915098 0.593 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
KCTD10


potassium channel tetramerization domain containing 10


chr3_+_51895621 0.592 ENST00000333127.3
IQCF2
IQ motif containing F2
chr11_+_61891445 0.591 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr17_-_5138099 0.591 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP



SLP adaptor and CSK interacting membrane protein



chr16_+_23652700 0.591 ENST00000300087.2
DCTN5
dynactin 5 (p25)
chr7_-_80551671 0.591 ENST00000419255.2
ENST00000544525.1
SEMA3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

chr20_-_1309809 0.589 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr4_+_57333756 0.589 ENST00000510663.1
ENST00000504757.1
SRP72

signal recognition particle 72kDa

chr3_-_179169330 0.587 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr13_+_49280951 0.582 ENST00000282018.3
CYSLTR2
cysteinyl leukotriene receptor 2
chr3_-_50375657 0.571 ENST00000395126.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr6_-_27114577 0.558 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr17_+_42925270 0.557 ENST00000253410.2
ENST00000587021.1
HIGD1B

HIG1 hypoxia inducible domain family, member 1B

chr16_+_15737124 0.555 ENST00000396355.1
ENST00000396353.2
NDE1

nudE neurodevelopment protein 1

chr5_+_74062806 0.551 ENST00000296802.5
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr18_-_61089665 0.551 ENST00000238497.5
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr1_-_9129735 0.549 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_+_148847371 0.547 ENST00000296051.2
ENST00000460120.1
HPS3

Hermansky-Pudlak syndrome 3

chr1_-_94147385 0.542 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr9_+_125132803 0.541 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_33938236 0.540 ENST00000361328.3
ENST00000373413.2
ZSCAN20

zinc finger and SCAN domain containing 20

chr9_+_97021572 0.540 ENST00000395395.2
ENST00000340911.4
ZNF169

zinc finger protein 169

chr3_-_156272872 0.539 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr4_-_99578789 0.536 ENST00000511651.1
ENST00000505184.1
TSPAN5

tetraspanin 5

chr3_-_28390415 0.535 ENST00000414162.1
ENST00000420543.2
AZI2

5-azacytidine induced 2

chr11_-_85565906 0.534 ENST00000544076.1
AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chrX_-_153718988 0.534 ENST00000263512.4
ENST00000393587.4
ENST00000453912.1
SLC10A3


solute carrier family 10, member 3


chr2_+_89998789 0.533 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr14_+_75469606 0.531 ENST00000266126.5
EIF2B2
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr18_+_10471826 0.528 ENST00000584596.2
APCDD1
adenomatosis polyposis coli down-regulated 1
chr12_-_110486348 0.524 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
C12orf76


chromosome 12 open reading frame 76


chr6_-_167571817 0.523 ENST00000366834.1
GPR31
G protein-coupled receptor 31
chr20_-_44540686 0.522 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
PLTP




phospholipid transfer protein




chr2_-_89545079 0.520 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chrX_+_151999511 0.520 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL


NAD(P) dependent steroid dehydrogenase-like


chr5_+_96079240 0.520 ENST00000515663.1
CAST
calpastatin
chr16_-_72206034 0.519 ENST00000537465.1
ENST00000237353.10
PMFBP1

polyamine modulated factor 1 binding protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.0 3.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.9 5.6 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.9 2.6 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.7 2.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 1.5 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 1.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.5 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.4 2.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.4 2.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.4 1.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 0.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.3 0.9 GO:0018874 benzoate metabolic process(GO:0018874)
0.3 6.8 GO:0016540 protein autoprocessing(GO:0016540)
0.3 0.9 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.3 0.9 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.3 0.9 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.3 1.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 1.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 0.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 1.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 0.8 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.3 1.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.3 0.8 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.3 1.0 GO:0010266 response to vitamin B1(GO:0010266)
0.3 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.2 2.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 2.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.5 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 1.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 1.4 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2 0.7 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 1.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 0.8 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 0.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 1.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 0.2 GO:0097242 beta-amyloid clearance(GO:0097242)
0.2 0.8 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.9 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 0.6 GO:0019085 early viral transcription(GO:0019085)
0.2 0.7 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 1.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2 0.4 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 0.6 GO:1903722 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.2 0.5 GO:0043473 pigmentation(GO:0043473)
0.2 0.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 0.2 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 0.8 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.6 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.6 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2 0.6 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.5 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763) positive regulation of myeloid cell differentiation(GO:0045639)
0.1 2.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.1 0.8 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 1.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.7 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.8 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.6 GO:0001555 oocyte growth(GO:0001555) positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.4 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.1 0.4 GO:0071812 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 0.6 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 2.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.7 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.7 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.1 0.3 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.8 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 1.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.4 GO:0019086 late viral transcription(GO:0019086)
0.1 0.6 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.7 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.5 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.4 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.6 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 1.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.5 GO:0032886 regulation of microtubule-based process(GO:0032886)
0.1 1.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 1.2 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 2.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.8 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 2.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.3 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.1 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.1 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 0.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 2.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.3 GO:0071706 tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 0.2 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 2.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 3.2 GO:1901998 toxin transport(GO:1901998)
0.1 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.4 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.6 GO:0000732 strand displacement(GO:0000732)
0.0 0.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 1.0 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.5 GO:0042908 heme transport(GO:0015886) xenobiotic transport(GO:0042908)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.5 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.3 GO:0016050 vesicle organization(GO:0016050)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0019043 establishment of viral latency(GO:0019043)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 1.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 2.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 1.5 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.9 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.4 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.1 GO:0097421 liver regeneration(GO:0097421)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.5 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.0 0.7 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.5 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.2 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0032479 regulation of type I interferon production(GO:0032479) type I interferon production(GO:0032606)
0.0 2.0 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 1.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0060348 bone development(GO:0060348)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027)
0.0 1.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 1.7 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 3.4 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0042325 regulation of phosphorylation(GO:0042325)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.0 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 1.2 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.9 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.5 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.0 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.9 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.1 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 1.6 GO:0005602 complement component C1 complex(GO:0005602)
0.3 1.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 1.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.2 0.9 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 1.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 2.2 GO:0005916 fascia adherens(GO:0005916)
0.1 1.2 GO:0036128 CatSper complex(GO:0036128)
0.1 0.6 GO:0055087 Ski complex(GO:0055087)
0.1 4.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.5 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 0.3 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.1 GO:0008278 cohesin complex(GO:0008278)
0.1 1.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.2 GO:0032797 SMN complex(GO:0032797)
0.1 1.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 1.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.5 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.7 GO:0097443 sorting endosome(GO:0097443)
0.1 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.6 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.6 GO:0000801 central element(GO:0000801)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.0 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0071203 WASH complex(GO:0071203)
0.0 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194) alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0031390 DNA replication factor C complex(GO:0005663) Ctf18 RFC-like complex(GO:0031390)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 3.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:1990393 3M complex(GO:1990393)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 3.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 3.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 1.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 1.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.5 1.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 2.1 GO:0004966 galanin receptor activity(GO:0004966)
0.4 1.5 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3 2.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 1.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 0.8 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 1.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 0.8 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 2.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.7 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.2 1.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.7 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 1.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.6 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.2 0.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.3 GO:0031433 telethonin binding(GO:0031433)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 0.7 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.2 3.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.5 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.5 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.4 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 1.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 3.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.2 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0005497 androgen binding(GO:0005497)
0.1 1.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.5 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.9 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.8 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 2.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.3 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 1.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 3.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 2.0 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.8 GO:0019864 IgG binding(GO:0019864)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 1.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 3.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0089720 caspase binding(GO:0089720)
0.0 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.6 GO:0031014 troponin T binding(GO:0031014)
0.0 3.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 11.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 2.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 3.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 2.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:1990446 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0035242 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 1.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 7.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 4.6 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 4.0 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 1.3 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 0.9 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.6 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 1.9 PID_MYC_PATHWAY C-MYC pathway
0.0 1.4 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 6.9 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.1 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.5 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.8 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.4 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.5 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 6.7 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.1 1.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.1 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.6 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.0 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 1.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.0 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.3 REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.5 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 1.0 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 2.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 2.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.5 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 5.0 REACTOME_TRANSLATION Genes involved in Translation
0.0 2.0 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 3.1 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.3 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor