Motif ID: SOX7

Z-value: 0.366


Transcription factors associated with SOX7:

Gene SymbolEntrez IDGene Name
SOX7 ENSG00000171056.6 SOX7
SOX7 ENSG00000258724.1 SOX7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10697281_10697365-0.067.8e-01Click!


Activity profile for motif SOX7.

activity profile for motif SOX7


Sorted Z-values histogram for motif SOX7

Sorted Z-values for motif SOX7



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_22379753 0.617 ENST00000397121.2
 ZNF676
zinc finger protein 676
chrY_+_14813160 0.547 ENST00000338981.3
 USP9Y
ubiquitin specific peptidase 9, Y-linked
chr16_-_20364030 0.425 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
 UMOD






uromodulin






chr4_+_69313145 0.423 ENST00000305363.4
 TMPRSS11E
transmembrane protease, serine 11E
chr16_-_20364122 0.419 ENST00000396138.4
ENST00000577168.1
 UMOD

uromodulin

chr10_-_61495760 0.379 ENST00000395347.1
 SLC16A9
solute carrier family 16, member 9
chr4_+_76995855 0.329 ENST00000355810.4
ENST00000349321.3
 ART3

ADP-ribosyltransferase 3

chr9_+_105757590 0.302 ENST00000374798.3
ENST00000487798.1
 CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr1_-_43751230 0.272 ENST00000523677.1
 C1orf210
chromosome 1 open reading frame 210
chr19_-_38916802 0.272 ENST00000587738.1
 RASGRP4
RAS guanyl releasing protein 4
chr4_-_47983519 0.254 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr1_+_100598691 0.236 ENST00000370143.1
ENST00000370141.2
 TRMT13

tRNA methyltransferase 13 homolog (S. cerevisiae)

chr12_+_1099675 0.205 ENST00000545318.2
 ERC1
ELKS/RAB6-interacting/CAST family member 1
chr1_+_223101757 0.195 ENST00000284476.6
 DISP1
dispatched homolog 1 (Drosophila)
chr19_-_38916822 0.185 ENST00000586305.1
 RASGRP4
RAS guanyl releasing protein 4
chr2_-_190445499 0.182 ENST00000261024.2
 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr19_-_38916839 0.182 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
 RASGRP4




RAS guanyl releasing protein 4




chr11_+_7618413 0.129 ENST00000528883.1
 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_-_3195981 0.128 ENST00000425384.2
ENST00000435043.2
 RP1-40E16.9

RP1-40E16.9

chr12_-_57443886 0.127 ENST00000300119.3
 MYO1A
myosin IA
chr5_+_161494521 0.119 ENST00000356592.3
 GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr12_-_57328187 0.117 ENST00000293502.1
 SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr16_-_28303360 0.112 ENST00000501520.1
 RP11-57A19.2
RP11-57A19.2
chr6_+_147527103 0.105 ENST00000179882.6
 STXBP5
syntaxin binding protein 5 (tomosyn)
chr16_+_33020496 0.098 ENST00000565407.2
 IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr12_-_39734783 0.097 ENST00000552961.1
 KIF21A
kinesin family member 21A
chr17_-_56082455 0.095 ENST00000578794.1
 RP11-159D12.5
Uncharacterized protein
chr2_-_88285309 0.095 ENST00000420840.2
 RGPD2
RANBP2-like and GRIP domain containing 2
chr4_-_177190364 0.094 ENST00000296525.3
 ASB5
ankyrin repeat and SOCS box containing 5
chr12_-_90049828 0.094 ENST00000261173.2
ENST00000348959.3
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr12_-_90049878 0.092 ENST00000359142.3
 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr16_-_33647696 0.089 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9

Uncharacterized protein

chr5_+_161494770 0.086 ENST00000414552.2
ENST00000361925.4
 GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

chr19_-_5784610 0.086 ENST00000390672.2
ENST00000419421.2
 PRR22

proline rich 22

chr10_+_122610687 0.085 ENST00000263461.6
 WDR11
WD repeat domain 11
chr11_-_62474803 0.081 ENST00000533982.1
ENST00000360796.5
 BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr11_+_3011093 0.080 ENST00000332881.2
 AC131971.1
HCG1782999; PRO0943; Uncharacterized protein
chr19_+_37837185 0.079 ENST00000541583.2
 HKR1
HKR1, GLI-Kruppel zinc finger family member
chr4_-_123377880 0.078 ENST00000226730.4
 IL2
interleukin 2
chr2_+_87144738 0.077 ENST00000559485.1
 RGPD1
RANBP2-like and GRIP domain containing 1
chr6_-_111804905 0.073 ENST00000358835.3
ENST00000435970.1
 REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr1_-_26394114 0.072 ENST00000374272.3
 TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr6_+_140175987 0.058 ENST00000414038.1
ENST00000431609.1
 RP5-899B16.1

RP5-899B16.1

chr13_-_28024681 0.056 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
 MTIF3


mitochondrial translational initiation factor 3


chr2_-_166930131 0.054 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr8_-_102803163 0.051 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
 NCALD






neurocalcin delta






chr6_+_42531798 0.050 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
 UBR2


ubiquitin protein ligase E3 component n-recognin 2


chrY_+_26997726 0.049 ENST00000382296.2
 DAZ4
deleted in azoospermia 4
chr6_+_150690028 0.045 ENST00000229447.5
ENST00000344419.3
 IYD

iodotyrosine deiodinase

chr10_+_5005445 0.045 ENST00000380872.4
 AKR1C1
aldo-keto reductase family 1, member C1
chr1_+_11724167 0.045 ENST00000376753.4
 FBXO6
F-box protein 6
chr6_-_86303833 0.036 ENST00000505648.1
 SNX14
sorting nexin 14
chr5_-_95158375 0.027 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX



glutaredoxin (thioltransferase)



chr5_-_95158644 0.027 ENST00000237858.6
 GLRX
glutaredoxin (thioltransferase)
chr10_+_96162242 0.027 ENST00000225235.4
 TBC1D12
TBC1 domain family, member 12
chr10_+_24738355 0.026 ENST00000307544.6
 KIAA1217
KIAA1217
chr1_+_158901329 0.023 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
 PYHIN1




pyrin and HIN domain family, member 1




chr2_+_3705785 0.023 ENST00000252505.3
 ALLC
allantoicase
chr8_-_19459993 0.019 ENST00000454498.2
ENST00000520003.1
 CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr6_-_29324054 0.016 ENST00000543825.1
 OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr14_-_106573756 0.015 ENST00000390601.2
 IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr17_-_39623681 0.013 ENST00000225899.3
 KRT32
keratin 32
chr10_-_17243579 0.011 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
 TRDMT1






tRNA aspartic acid methyltransferase 1






chr10_-_5046042 0.011 ENST00000421196.3
ENST00000455190.1
 AKR1C2

aldo-keto reductase family 1, member C2

chr12_+_64173583 0.010 ENST00000261234.6
 TMEM5
transmembrane protein 5
chr18_+_32820990 0.007 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
 ZNF397





zinc finger protein 397





chr12_-_58027138 0.006 ENST00000341156.4
 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr7_-_143966381 0.005 ENST00000487179.1
 CTAGE8
CTAGE family, member 8
chr16_+_28303804 0.001 ENST00000341901.4
 SBK1
SH3 domain binding kinase 1
chrX_+_69353284 0.001 ENST00000342206.6
ENST00000356413.4
 IGBP1

immunoglobulin (CD79A) binding protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.2 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.0 GO:0047718 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation