Motif ID: SMAD4

Z-value: 1.543


Transcription factors associated with SMAD4:

Gene SymbolEntrez IDGene Name
SMAD4 ENSG00000141646.9 SMAD4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48494361_48494426-0.779.1e-06Click!


Activity profile for motif SMAD4.

activity profile for motif SMAD4


Sorted Z-values histogram for motif SMAD4

Sorted Z-values for motif SMAD4



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51456321 6.481 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr19_-_51456344 5.991 ENST00000336334.3
ENST00000593428.1
KLK5

kallikrein-related peptidase 5

chr19_-_51456198 4.169 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr1_+_152956549 3.200 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chrX_-_48328551 2.823 ENST00000376876.3
SLC38A5
solute carrier family 38, member 5
chrX_-_48328631 2.757 ENST00000429543.1
ENST00000317669.5
SLC38A5

solute carrier family 38, member 5

chr1_-_28520447 2.710 ENST00000539896.1
PTAFR
platelet-activating factor receptor
chr1_-_24469602 2.652 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr1_+_45212074 2.580 ENST00000372217.1
KIF2C
kinesin family member 2C
chr19_-_11688447 2.549 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr2_-_113594279 2.535 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr5_-_39219705 2.532 ENST00000351578.6
FYB
FYN binding protein
chr2_-_31360887 2.482 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)


chr1_+_45212051 2.461 ENST00000372222.3
KIF2C
kinesin family member 2C
chr19_-_11688500 2.439 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr7_+_48128316 2.278 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr7_+_48128194 2.275 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1


uridine phosphorylase 1


chr22_+_30752606 2.223 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157


coiled-coil domain containing 157


chr5_-_39219641 2.210 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB



FYN binding protein



chr1_-_28520384 2.185 ENST00000305392.3
PTAFR
platelet-activating factor receptor
chr1_+_152486950 2.182 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr11_-_107729887 2.116 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr5_+_148521381 2.112 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr10_+_75670862 2.056 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
PLAU


plasminogen activator, urokinase


chr19_-_43032532 2.055 ENST00000403461.1
ENST00000352591.5
ENST00000358394.3
ENST00000403444.3
ENST00000308072.4
ENST00000599389.1
ENST00000351134.3
ENST00000161559.6
CEACAM1







carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)







chr10_+_88718397 2.004 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr17_+_42081914 1.985 ENST00000293404.3
ENST00000589767.1
NAGS

N-acetylglutamate synthase

chr2_-_208030647 1.937 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_-_7297519 1.934 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chr9_+_140119618 1.930 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr10_+_88718314 1.917 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr22_-_37880543 1.916 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_+_31488433 1.885 ENST00000455608.1
SMTN
smoothelin
chr15_+_40453204 1.880 ENST00000287598.6
ENST00000412359.3
BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

chr5_+_148521046 1.856 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3


actin binding LIM protein family, member 3


chr19_-_41859814 1.848 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr12_-_57634475 1.834 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr5_+_148521136 1.814 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr12_-_54813229 1.813 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_-_139891165 1.812 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr1_+_203595903 1.800 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr19_-_49015050 1.800 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chrX_-_153599578 1.778 ENST00000360319.4
ENST00000344736.4
FLNA

filamin A, alpha

chr1_+_203595689 1.773 ENST00000357681.5
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr4_-_111119804 1.748 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr22_-_37823468 1.723 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr2_+_30454390 1.716 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr15_+_81071684 1.706 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199


KIAA1199


chr17_-_76899275 1.698 ENST00000322630.2
ENST00000586713.1
DDC8

Protein DDC8 homolog

chr2_+_33359687 1.692 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr19_+_35645618 1.666 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5






FXYD domain containing ion transport regulator 5






chr12_-_8815215 1.663 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr10_+_102891048 1.658 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr1_-_9189229 1.649 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr21_+_30502806 1.612 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr12_-_8815299 1.600 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr2_+_33359646 1.588 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr2_-_70780572 1.584 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr17_+_74372662 1.583 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr17_+_74381343 1.559 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr15_-_89764929 1.552 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr14_-_24732368 1.500 ENST00000544573.1
TGM1
transglutaminase 1
chr15_+_67420441 1.492 ENST00000558894.1
SMAD3
SMAD family member 3
chr19_-_51141196 1.482 ENST00000338916.4
SYT3
synaptotagmin III
chr7_-_107642348 1.463 ENST00000393561.1
LAMB1
laminin, beta 1
chr2_+_113735575 1.449 ENST00000376489.2
ENST00000259205.4
IL36G

interleukin 36, gamma

chr20_+_60174827 1.431 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr3_-_48632593 1.426 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr14_-_24732403 1.408 ENST00000206765.6
TGM1
transglutaminase 1
chrX_-_153602991 1.402 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr20_+_30598231 1.395 ENST00000300415.8
ENST00000262659.8
CCM2L

cerebral cavernous malformation 2-like

chr16_+_23690138 1.391 ENST00000300093.4
PLK1
polo-like kinase 1
chrX_+_135279179 1.389 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr19_+_42301079 1.374 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr2_-_228028829 1.358 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr5_+_150404904 1.350 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr1_+_26605618 1.349 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr7_+_86274145 1.348 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3


glutamate receptor, metabotropic 3


chr9_-_123639445 1.345 ENST00000312189.6
PHF19
PHD finger protein 19
chr16_-_46655538 1.331 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr16_+_66638616 1.318 ENST00000564060.1
ENST00000565922.1
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr11_-_61647935 1.288 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr2_+_102456277 1.284 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr22_+_44319648 1.275 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr20_+_42984330 1.267 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr2_-_71062938 1.264 ENST00000410009.3
CD207
CD207 molecule, langerin
chr17_-_34122596 1.258 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr3_+_50316458 1.256 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr19_+_49055332 1.248 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr3_-_48594248 1.239 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4





chr11_+_72929402 1.239 ENST00000393596.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr18_-_33077556 1.236 ENST00000589273.1
ENST00000586489.1
INO80C

INO80 complex subunit C

chr1_+_11751748 1.235 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr12_+_75874460 1.225 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr7_-_142120321 1.221 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr2_-_9563575 1.215 ENST00000488451.1
ENST00000238091.4
ENST00000355346.4
ITGB1BP1


integrin beta 1 binding protein 1


chr11_+_35211429 1.205 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44


CD44 molecule (Indian blood group)


chr1_-_110283138 1.201 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr19_-_44285401 1.201 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr12_-_49365501 1.194 ENST00000403957.1
ENST00000301061.4
WNT10B

wingless-type MMTV integration site family, member 10B

chr16_+_68877496 1.190 ENST00000261778.1
TANGO6
transport and golgi organization 6 homolog (Drosophila)
chr1_+_153388993 1.183 ENST00000368729.4
S100A7A
S100 calcium binding protein A7A
chr1_+_155178518 1.182 ENST00000316721.4
MTX1
metaxin 1
chr11_+_35211511 1.179 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr3_+_154797877 1.174 ENST00000462745.1
ENST00000493237.1
MME

membrane metallo-endopeptidase

chr10_-_75193308 1.169 ENST00000299432.2
MSS51
MSS51 mitochondrial translational activator
chr17_-_39780819 1.163 ENST00000311208.8
KRT17
keratin 17
chr20_-_23967432 1.153 ENST00000286890.4
ENST00000278765.4
GGTLC1

gamma-glutamyltransferase light chain 1

chr14_-_106830057 1.152 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr19_-_51017881 1.147 ENST00000601207.1
ENST00000598657.1
ENST00000376916.3
ASPDH


aspartate dehydrogenase domain containing


chr22_+_44319619 1.146 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr3_-_47950745 1.125 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr20_-_33880204 1.120 ENST00000374408.3
FAM83C
family with sequence similarity 83, member C
chr2_-_27718052 1.120 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr22_-_21579843 1.107 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr6_-_112080256 1.106 ENST00000462856.2
ENST00000229471.4
FYN

FYN oncogene related to SRC, FGR, YES

chr1_+_155178481 1.104 ENST00000368376.3
MTX1
metaxin 1
chr14_+_65171315 1.102 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr10_+_50822480 1.090 ENST00000455728.2
CHAT
choline O-acetyltransferase
chr7_+_24613034 1.080 ENST00000409761.1
ENST00000396475.2
MPP6

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

chr11_-_568369 1.070 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr9_+_126118449 1.063 ENST00000359999.3
ENST00000373631.3
CRB2

crumbs homolog 2 (Drosophila)

chr12_-_99038732 1.059 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP



IKBKB interacting protein



chr2_-_112237835 1.057 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG

MIR4435-1 host gene (non-protein coding)

chr8_-_145028013 1.055 ENST00000354958.2
PLEC
plectin
chr22_-_30234218 1.051 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2


activating signal cointegrator 1 complex subunit 2


chr4_+_154073469 1.049 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr8_-_125486755 1.041 ENST00000499418.2
ENST00000530778.1
RNF139-AS1

RNF139 antisense RNA 1 (head to head)

chr17_+_9066252 1.040 ENST00000436734.1
NTN1
netrin 1
chr6_-_35656685 1.038 ENST00000539068.1
ENST00000540787.1
FKBP5

FK506 binding protein 5

chr17_-_7297833 1.036 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr20_+_42965626 1.034 ENST00000217043.2
R3HDML
R3H domain containing-like
chr12_-_6960407 1.024 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3



cell division cycle associated 3



chr14_+_20937538 1.024 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr1_+_183155373 1.022 ENST00000493293.1
ENST00000264144.4
LAMC2

laminin, gamma 2

chr12_+_75874580 1.022 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr1_+_156254070 1.021 ENST00000405535.2
ENST00000456810.1
TMEM79

transmembrane protein 79

chr9_+_34990219 1.016 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr6_-_131291572 1.015 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_-_50143452 1.012 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr7_-_23510086 1.010 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr19_-_43702231 1.010 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr17_+_41476327 1.010 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr20_-_6103666 1.009 ENST00000536936.1
FERMT1
fermitin family member 1
chr6_-_41863098 1.007 ENST00000373006.1
USP49
ubiquitin specific peptidase 49
chr20_+_31619454 1.007 ENST00000349552.1
BPIFB6
BPI fold containing family B, member 6
chr19_-_44031341 1.002 ENST00000600651.1
ETHE1
ethylmalonic encephalopathy 1
chr1_+_209859510 0.995 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr3_+_130569592 0.987 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr7_+_134551583 0.983 ENST00000435928.1
CALD1
caldesmon 1
chr12_+_47473369 0.978 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr3_+_39371191 0.970 ENST00000326306.4
CCR8
chemokine (C-C motif) receptor 8
chr19_-_44031375 0.970 ENST00000292147.2
ETHE1
ethylmalonic encephalopathy 1
chr17_-_43487741 0.969 ENST00000455881.1
ARHGAP27
Rho GTPase activating protein 27
chr14_-_91720224 0.967 ENST00000238699.3
ENST00000531499.2
GPR68

G protein-coupled receptor 68

chr16_+_31483374 0.961 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr4_+_187187098 0.952 ENST00000403665.2
ENST00000264692.4
F11

coagulation factor XI

chrX_-_48815633 0.950 ENST00000428668.2
OTUD5
OTU domain containing 5
chr22_-_24641027 0.949 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5




gamma-glutamyltransferase 5




chr15_-_70388943 0.948 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3






transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)






chr19_-_14629224 0.943 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr15_+_75182346 0.942 ENST00000569931.1
ENST00000352410.4
ENST00000566377.1
ENST00000569233.1
ENST00000567132.1
ENST00000564633.1
ENST00000568907.1
ENST00000563422.1
ENST00000564003.1
ENST00000562800.1
ENST00000563786.1
ENST00000535694.1
ENST00000323744.6
ENST00000568828.1
ENST00000562606.1
ENST00000565576.1
ENST00000567570.1
MPI
















mannose phosphate isomerase
















chr1_-_41131326 0.941 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr6_-_35656712 0.940 ENST00000357266.4
ENST00000542713.1
FKBP5

FK506 binding protein 5

chr1_-_149908710 0.935 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
MTMR11


myotubularin related protein 11


chr15_-_70388599 0.934 ENST00000560996.1
ENST00000558201.1
TLE3

transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

chr6_+_43738444 0.934 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA








vascular endothelial growth factor A








chr19_+_54371114 0.930 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM



myeloid-associated differentiation marker



chr2_+_174219548 0.929 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7




cell division cycle associated 7




chr1_-_214638146 0.921 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr2_+_113816685 0.920 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr11_-_67120974 0.917 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr12_-_53207842 0.914 ENST00000458244.2
KRT4
keratin 4
chr12_+_75874984 0.913 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr1_-_201368707 0.906 ENST00000391967.2
LAD1
ladinin 1
chr13_-_21750659 0.895 ENST00000400018.3
ENST00000314759.5
SKA3

spindle and kinetochore associated complex subunit 3

chr22_-_20368028 0.892 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr1_+_152691998 0.891 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr3_-_195619579 0.883 ENST00000428187.1
TNK2
tyrosine kinase, non-receptor, 2
chr9_+_35673853 0.881 ENST00000378357.4
CA9
carbonic anhydrase IX
chr9_+_75263565 0.879 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr15_-_74504560 0.876 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chr3_-_42743006 0.870 ENST00000310417.5
HHATL
hedgehog acyltransferase-like
chr5_+_60933634 0.864 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr16_+_66638003 0.853 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3





CKLF-like MARVEL transmembrane domain containing 3





chr16_+_3070356 0.852 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A


tumor necrosis factor receptor superfamily, member 12A


chr3_-_12800751 0.846 ENST00000435218.2
ENST00000435575.1
TMEM40

transmembrane protein 40

chr1_-_24127256 0.834 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr7_+_36429409 0.834 ENST00000265748.2
ANLN
anillin, actin binding protein
chr15_-_83953466 0.831 ENST00000345382.2
BNC1
basonuclin 1
chr2_+_90458201 0.829 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr12_-_6961050 0.824 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr8_+_107282368 0.824 ENST00000521369.2
RP11-395G23.3
RP11-395G23.3
chr22_+_22988816 0.821 ENST00000480559.1
ENST00000448514.1
GGTLC2

gamma-glutamyltransferase light chain 2

chr2_+_87769459 0.821 ENST00000414030.1
ENST00000437561.1
LINC00152

long intergenic non-protein coding RNA 152

chr10_-_90712520 0.818 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr7_-_107443652 0.817 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr11_-_64851496 0.815 ENST00000404147.3
ENST00000275517.3
CDCA5

cell division cycle associated 5

chr6_+_12290586 0.814 ENST00000379375.5
EDN1
endothelin 1
chr8_+_82192501 0.814 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 16.6 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.6 4.9 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
1.2 3.6 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.1 4.6 GO:0006218 uridine catabolic process(GO:0006218)
1.0 3.1 GO:0046521 sphingoid catabolic process(GO:0046521)
1.0 5.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.0 2.9 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.8 2.5 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.8 0.8 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.7 2.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.7 2.1 GO:0002856 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) insulin catabolic process(GO:1901143)
0.6 3.8 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.6 1.9 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.6 1.8 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.6 1.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.5 1.6 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.5 1.1 GO:0010165 response to X-ray(GO:0010165)
0.5 5.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 1.9 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.5 1.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 5.8 GO:0015816 glycine transport(GO:0015816)
0.4 0.4 GO:1901205 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.4 1.6 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.4 1.2 GO:0051885 positive regulation of anagen(GO:0051885)
0.4 3.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.7 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.3 1.0 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.3 1.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 2.0 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.3 2.0 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.3 0.3 GO:0046108 uridine metabolic process(GO:0046108)
0.3 1.2 GO:0000103 sulfate assimilation(GO:0000103)
0.3 5.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 0.9 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 1.2 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.3 1.8 GO:0042335 cuticle development(GO:0042335)
0.3 1.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 0.9 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.3 0.9 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.3 1.4 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.3 2.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 0.8 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.3 0.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 0.8 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.3 0.8 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.3 2.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.3 1.0 GO:0051884 anagen(GO:0042640) regulation of anagen(GO:0051884)
0.3 1.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 1.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 0.7 GO:0007412 axon target recognition(GO:0007412)
0.2 1.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 1.2 GO:0046449 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.2 1.2 GO:0021553 olfactory nerve development(GO:0021553)
0.2 0.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.7 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 1.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300)
0.2 2.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 0.4 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.2 1.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.6 GO:0019417 sulfur oxidation(GO:0019417)
0.2 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 1.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 2.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.2 1.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 1.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.4 GO:0070305 response to cGMP(GO:0070305)
0.2 0.8 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 0.6 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.2 1.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.2 0.7 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.5 GO:0021558 trochlear nerve development(GO:0021558)
0.2 0.4 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.9 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.1 GO:0061364 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) response to cortisol(GO:0051414) apoptotic process involved in luteolysis(GO:0061364)
0.2 0.9 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.7 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.2 0.5 GO:0060545 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 0.7 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 0.3 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.2 0.5 GO:0050894 determination of affect(GO:0050894)
0.2 0.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 2.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.8 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 0.8 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 0.6 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 0.6 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.2 0.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 0.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.4 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.7 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 2.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.0 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.4 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.7 GO:0010193 response to ozone(GO:0010193)
0.1 0.8 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 0.9 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.5 GO:0072376 protein activation cascade(GO:0072376)
0.1 0.7 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 1.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.8 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.7 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.4 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.5 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.6 GO:0048749 compound eye development(GO:0048749)
0.1 0.4 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 1.8 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 1.2 GO:0046541 saliva secretion(GO:0046541)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 1.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.5 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.1 0.3 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1 1.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.0 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.7 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 2.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 5.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.4 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 4.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.3 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.3 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) detection of chemical stimulus involved in sensory perception of pain(GO:0050968) response to capsazepine(GO:1901594)
0.1 0.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.9 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.5 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.4 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.4 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.4 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 1.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.7 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.4 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.4 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.3 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.1 0.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 3.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.9 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.4 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.7 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.1 9.0 GO:0070268 cornification(GO:0070268)
0.1 0.3 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 1.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.4 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.3 GO:0007276 gamete generation(GO:0007276)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.7 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 2.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.2 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 7.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 0.2 GO:2001137 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) positive regulation of endocytic recycling(GO:2001137)
0.1 0.1 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.1 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.3 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0007398 ectoderm development(GO:0007398)
0.1 0.8 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 1.9 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.4 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643)
0.1 0.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 1.3 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.2 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 1.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.5 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0015824 proline transport(GO:0015824) proline transmembrane transport(GO:0035524)
0.0 1.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.4 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.7 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.7 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 2.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.3 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.0 1.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.5 GO:0006935 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.6 GO:0060324 face development(GO:0060324)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.4 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.4 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 2.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 1.2 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 0.1 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 1.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.5 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.0 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.0 0.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.0 0.8 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.4 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.9 GO:0033574 response to testosterone(GO:0033574)
0.0 0.1 GO:0035814 regulation of systemic arterial blood pressure by vasopressin(GO:0001992) negative regulation of renal sodium excretion(GO:0035814)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.5 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.4 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0007015 actin filament organization(GO:0007015)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.0 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 1.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.0 GO:0060481 bronchus development(GO:0060433) lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 1.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.6 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 0.6 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.4 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.3 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.6 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 1.2 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.2 GO:0072678 T cell migration(GO:0072678)
0.0 0.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.5 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 17.4 GO:0097209 epidermal lamellar body(GO:0097209)
1.1 3.2 GO:0031523 Myb complex(GO:0031523)
0.8 2.5 GO:0005607 laminin-2 complex(GO:0005607)
0.5 1.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.3 1.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 7.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 0.8 GO:1990032 parallel fiber(GO:1990032)
0.3 4.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 0.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.7 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.2 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 1.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 0.5 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.6 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.1 GO:0071546 pi-body(GO:0071546)
0.1 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 2.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 2.6 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 5.8 GO:0001533 cornified envelope(GO:0001533)
0.1 3.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 0.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.8 GO:0000801 central element(GO:0000801)
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.8 GO:0008278 cohesin complex(GO:0008278)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.3 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
0.1 1.7 GO:0097342 ripoptosome(GO:0097342)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 9.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.7 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 2.4 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.3 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 7.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.1 0.4 GO:0034448 EGO complex(GO:0034448)
0.1 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 1.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 6.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 2.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 3.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0070161 anchoring junction(GO:0070161)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 8.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 3.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 11.0 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0008305 integrin complex(GO:0008305)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 1.0 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 7.5 GO:0044297 cell body(GO:0044297)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
1.0 5.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
1.0 4.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.8 3.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 3.3 GO:0050436 microfibril binding(GO:0050436)
0.5 5.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.5 5.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.5 1.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 1.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 2.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 2.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.4 2.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 2.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 5.2 GO:0008199 ferric iron binding(GO:0008199)
0.4 1.5 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.4 1.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 1.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.3 3.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 5.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 2.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 1.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 0.9 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.3 0.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 3.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 1.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 1.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.7 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.2 2.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 5.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 1.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 0.8 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 1.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 1.1 GO:0042806 fucose binding(GO:0042806)
0.2 0.7 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 1.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 2.0 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 1.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.2 1.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 1.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 1.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.4 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.5 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.5 GO:0031877 somatostatin receptor binding(GO:0031877)
0.2 1.3 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 2.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.3 GO:0042731 PH domain binding(GO:0042731)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.4 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 3.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.3 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.6 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.1 0.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 2.0 GO:0043295 glutathione binding(GO:0043295)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.8 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.1 1.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 3.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.7 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.3 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 2.1 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 2.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.2 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 2.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.2 GO:0031432 titin binding(GO:0031432)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0004882 androgen receptor activity(GO:0004882)
0.1 2.1 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.5 GO:0017166 vinculin binding(GO:0017166)
0.1 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0017022 myosin binding(GO:0017022)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 5.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 15.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 1.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 1.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.6 GO:0016918 retinal binding(GO:0016918)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.6 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 2.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0017016 Ras GTPase binding(GO:0017016)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 4.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 2.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0031078 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.4 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 2.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 6.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.8 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 4.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 4.7 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 5.3 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.3 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.7 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.2 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.7 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.5 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 1.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.2 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.7 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.4 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 1.0 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.6 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID_INSULIN_PATHWAY Insulin Pathway
0.0 3.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.2 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 7.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 5.3 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 4.6 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 4.1 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 2.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.5 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.5 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 2.9 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 0.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.3 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 2.1 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.2 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 1.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.1 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME_SIGNALING_BY_ERBB2 Genes involved in Signaling by ERBB2
0.0 0.4 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.4 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.1 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.6 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 3.5 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_IL_2_SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 1.0 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones