Motif ID: RUNX1_RUNX2
Z-value: 1.059
Transcription factors associated with RUNX1_RUNX2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
RUNX1 | ENSG00000159216.14 | RUNX1 |
RUNX2 | ENSG00000124813.16 | RUNX2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
RUNX2 | hg19_v2_chr6_+_45389893_45389914 | -0.53 | 7.2e-03 | Click! |
RUNX1 | hg19_v2_chr21_-_36421401_36421462 | -0.37 | 7.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.1 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
0.5 | 1.6 | GO:0070428 | negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
0.5 | 3.5 | GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) |
0.4 | 1.7 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
0.4 | 1.2 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
0.4 | 2.6 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
0.4 | 1.1 | GO:0001798 | positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) |
0.3 | 3.2 | GO:0015889 | cobalamin transport(GO:0015889) |
0.2 | 4.4 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
0.2 | 0.7 | GO:0018057 | peptidyl-lysine oxidation(GO:0018057) |
0.2 | 0.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.2 | 0.2 | GO:0002590 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) |
0.2 | 0.9 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.2 | 0.9 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
0.2 | 1.1 | GO:1990822 | regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822) |
0.2 | 0.5 | GO:1903568 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
0.2 | 0.5 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.2 | 1.2 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
0.2 | 4.3 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
0.2 | 0.5 | GO:0042495 | detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
0.2 | 0.5 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
0.2 | 0.2 | GO:1902107 | positive regulation of leukocyte differentiation(GO:1902107) |
0.2 | 0.8 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
0.2 | 0.5 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
0.2 | 0.5 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
0.1 | 0.4 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
0.1 | 0.1 | GO:2001190 | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
0.1 | 0.4 | GO:0060545 | CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452) |
0.1 | 0.6 | GO:0072156 | distal tubule morphogenesis(GO:0072156) |
0.1 | 1.0 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
0.1 | 0.4 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
0.1 | 0.4 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
0.1 | 0.9 | GO:0023021 | termination of signal transduction(GO:0023021) |
0.1 | 0.4 | GO:0072683 | T cell extravasation(GO:0072683) |
0.1 | 0.4 | GO:0035915 | pore formation in membrane of other organism(GO:0035915) |
0.1 | 0.4 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
0.1 | 0.2 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
0.1 | 0.7 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.1 | 0.2 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
0.1 | 0.2 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
0.1 | 0.4 | GO:0033214 | iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308) |
0.1 | 3.1 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.1 | 0.4 | GO:0034239 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
0.1 | 0.3 | GO:1905246 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
0.1 | 0.5 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
0.1 | 0.7 | GO:0061526 | acetylcholine secretion(GO:0061526) |
0.1 | 0.4 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
0.1 | 1.0 | GO:0015705 | iodide transport(GO:0015705) |
0.1 | 0.4 | GO:0036269 | swimming behavior(GO:0036269) |
0.1 | 0.1 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
0.1 | 2.4 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.1 | 2.4 | GO:0006068 | ethanol catabolic process(GO:0006068) |
0.1 | 0.5 | GO:0032571 | response to vitamin K(GO:0032571) |
0.1 | 0.2 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.1 | 1.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.1 | 0.3 | GO:0002625 | regulation of T cell antigen processing and presentation(GO:0002625) |
0.1 | 0.3 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
0.1 | 0.5 | GO:0072313 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
0.1 | 0.4 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
0.1 | 0.4 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
0.1 | 0.1 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
0.1 | 0.2 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
0.1 | 0.2 | GO:0003064 | regulation of heart rate by hormone(GO:0003064) |
0.1 | 0.7 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
0.1 | 0.4 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
0.1 | 0.4 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
0.1 | 0.1 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) negative regulation of binding of sperm to zona pellucida(GO:2000360) |
0.1 | 1.4 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.1 | 0.3 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
0.1 | 0.3 | GO:0000103 | sulfate assimilation(GO:0000103) |
0.1 | 1.4 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
0.1 | 1.0 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
0.1 | 1.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.1 | 0.2 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
0.1 | 0.4 | GO:0050955 | thermoception(GO:0050955) |
0.1 | 0.5 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
0.1 | 0.3 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
0.1 | 1.5 | GO:0006768 | biotin metabolic process(GO:0006768) |
0.1 | 0.2 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
0.1 | 0.4 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
0.1 | 0.2 | GO:2000870 | regulation of progesterone secretion(GO:2000870) |
0.1 | 0.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 0.1 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.1 | 0.2 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162) |
0.1 | 0.4 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
0.1 | 0.4 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
0.1 | 1.1 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.1 | 0.2 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
0.1 | 0.3 | GO:2000721 | pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721) |
0.1 | 0.4 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
0.1 | 0.9 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.1 | 0.3 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
0.1 | 0.2 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
0.1 | 0.3 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
0.1 | 0.2 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.1 | 0.1 | GO:0045799 | positive regulation of chromatin assembly or disassembly(GO:0045799) |
0.1 | 0.3 | GO:0015692 | lead ion transport(GO:0015692) |
0.1 | 0.3 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
0.1 | 0.1 | GO:0060454 | positive regulation of gastric acid secretion(GO:0060454) |
0.1 | 1.3 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
0.1 | 0.4 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
0.1 | 0.3 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
0.1 | 0.4 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
0.1 | 0.2 | GO:0015822 | mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822) |
0.1 | 0.3 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
0.1 | 0.5 | GO:0033227 | dsRNA transport(GO:0033227) |
0.1 | 0.5 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
0.1 | 0.8 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.1 | 0.2 | GO:1904106 | protein localization to microvillus(GO:1904106) |
0.1 | 0.2 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
0.1 | 0.9 | GO:0015866 | ADP transport(GO:0015866) |
0.1 | 0.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
0.1 | 0.2 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
0.1 | 0.3 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
0.1 | 1.1 | GO:0070986 | left/right axis specification(GO:0070986) |
0.1 | 0.2 | GO:0036309 | protein localization to M-band(GO:0036309) |
0.1 | 0.4 | GO:0045007 | depurination(GO:0045007) |
0.1 | 0.2 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
0.1 | 0.4 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.1 | 0.6 | GO:0034214 | protein hexamerization(GO:0034214) |
0.1 | 0.3 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.2 | GO:0032053 | ciliary basal body organization(GO:0032053) |
0.1 | 0.3 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
0.1 | 0.2 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
0.1 | 0.2 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
0.1 | 0.2 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
0.1 | 0.2 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
0.1 | 0.7 | GO:0006527 | arginine catabolic process(GO:0006527) |
0.1 | 0.2 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.1 | 0.3 | GO:1904970 | brush border assembly(GO:1904970) |
0.1 | 0.6 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
0.1 | 0.2 | GO:0043602 | nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) |
0.0 | 0.1 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
0.0 | 0.3 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.0 | 0.4 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.0 | 0.4 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
0.0 | 0.1 | GO:1904808 | regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808) |
0.0 | 0.6 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
0.0 | 0.3 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
0.0 | 0.2 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
0.0 | 0.2 | GO:0019046 | release from viral latency(GO:0019046) |
0.0 | 0.1 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
0.0 | 0.2 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
0.0 | 0.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.5 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
0.0 | 0.1 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
0.0 | 0.1 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
0.0 | 0.1 | GO:1903697 | negative regulation of microvillus assembly(GO:1903697) |
0.0 | 0.6 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.0 | 0.0 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
0.0 | 0.1 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) spindle assembly involved in meiosis(GO:0090306) |
0.0 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.0 | 1.1 | GO:0001562 | response to protozoan(GO:0001562) |
0.0 | 0.4 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
0.0 | 0.5 | GO:0046831 | regulation of RNA export from nucleus(GO:0046831) |
0.0 | 0.1 | GO:0060214 | endocardium formation(GO:0060214) |
0.0 | 0.2 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
0.0 | 0.3 | GO:0010454 | negative regulation of cell fate commitment(GO:0010454) |
0.0 | 0.1 | GO:0070842 | aggresome assembly(GO:0070842) |
0.0 | 0.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.0 | 0.2 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 0.4 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
0.0 | 0.1 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
0.0 | 0.5 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.0 | 0.2 | GO:0035425 | autocrine signaling(GO:0035425) |
0.0 | 0.2 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 0.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
0.0 | 0.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.0 | 0.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 0.7 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.0 | 0.1 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
0.0 | 0.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.1 | GO:2000053 | regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) |
0.0 | 0.3 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.0 | 0.1 | GO:0001555 | oocyte growth(GO:0001555) |
0.0 | 1.4 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
0.0 | 0.5 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
0.0 | 0.7 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.0 | 1.8 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
0.0 | 0.2 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
0.0 | 0.1 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
0.0 | 0.1 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
0.0 | 0.1 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.0 | 0.1 | GO:1902310 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.0 | 0.1 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
0.0 | 0.2 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
0.0 | 0.3 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 0.4 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
0.0 | 0.1 | GO:1904640 | response to methionine(GO:1904640) |
0.0 | 0.6 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
0.0 | 0.0 | GO:1900133 | regulation of renin secretion into blood stream(GO:1900133) |
0.0 | 0.1 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
0.0 | 0.7 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
0.0 | 0.2 | GO:0051552 | flavone metabolic process(GO:0051552) |
0.0 | 0.3 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
0.0 | 0.2 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.0 | 0.4 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.0 | 1.2 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.0 | 0.1 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
0.0 | 0.1 | GO:0045726 | positive regulation of integrin biosynthetic process(GO:0045726) |
0.0 | 0.2 | GO:0002385 | mucosal immune response(GO:0002385) |
0.0 | 0.1 | GO:0010725 | regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) |
0.0 | 1.8 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
0.0 | 0.1 | GO:0036512 | trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) |
0.0 | 0.4 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
0.0 | 0.1 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.0 | 0.1 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
0.0 | 0.2 | GO:0030242 | pexophagy(GO:0030242) |
0.0 | 0.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.0 | 0.1 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) |
0.0 | 0.3 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.0 | 0.1 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
0.0 | 0.5 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.0 | 0.2 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
0.0 | 0.1 | GO:0009386 | translational attenuation(GO:0009386) |
0.0 | 0.2 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
0.0 | 0.1 | GO:2000729 | positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
0.0 | 0.1 | GO:0061101 | neuroendocrine cell differentiation(GO:0061101) |
0.0 | 0.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.0 | 0.2 | GO:0072396 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
0.0 | 0.1 | GO:0001983 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
0.0 | 0.1 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.2 | GO:0071569 | protein ufmylation(GO:0071569) |
0.0 | 0.6 | GO:1900116 | extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.0 | 0.2 | GO:0034088 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
0.0 | 0.2 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.2 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
0.0 | 0.2 | GO:0071839 | apoptotic process in bone marrow(GO:0071839) |
0.0 | 0.2 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
0.0 | 0.1 | GO:2000259 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
0.0 | 0.1 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
0.0 | 0.1 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
0.0 | 0.0 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.0 | 0.1 | GO:0034486 | vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) |
0.0 | 0.2 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.0 | 0.1 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
0.0 | 0.3 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.0 | 0.2 | GO:0030916 | otic vesicle formation(GO:0030916) |
0.0 | 0.1 | GO:2001015 | negative regulation of skeletal muscle cell differentiation(GO:2001015) |
0.0 | 0.4 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.0 | 0.3 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.0 | 0.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
0.0 | 0.1 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
0.0 | 0.6 | GO:0034389 | lipid particle organization(GO:0034389) |
0.0 | 0.4 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
0.0 | 0.5 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.0 | 0.2 | GO:0001660 | fever generation(GO:0001660) |
0.0 | 0.1 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
0.0 | 0.3 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.0 | 0.0 | GO:0046545 | development of primary female sexual characteristics(GO:0046545) |
0.0 | 0.3 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
0.0 | 0.1 | GO:1903644 | regulation of protein folding(GO:1903332) regulation of chaperone-mediated protein folding(GO:1903644) |
0.0 | 0.2 | GO:0032306 | regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) |
0.0 | 0.0 | GO:1903978 | regulation of microglial cell activation(GO:1903978) |
0.0 | 0.1 | GO:1903517 | regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824) |
0.0 | 0.1 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.0 | 0.1 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
0.0 | 0.0 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
0.0 | 0.1 | GO:0007402 | ganglion mother cell fate determination(GO:0007402) |
0.0 | 0.1 | GO:0060174 | limb bud formation(GO:0060174) |
0.0 | 0.1 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.0 | 0.1 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
0.0 | 0.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.0 | 0.2 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.0 | 0.7 | GO:0010574 | regulation of vascular endothelial growth factor production(GO:0010574) |
0.0 | 0.2 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.0 | 0.2 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
0.0 | 0.2 | GO:0072189 | ureter development(GO:0072189) |
0.0 | 0.1 | GO:0048318 | axial mesoderm development(GO:0048318) |
0.0 | 0.1 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.0 | 0.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.2 | GO:0002456 | T cell mediated immunity(GO:0002456) |
0.0 | 0.2 | GO:0051057 | positive regulation of small GTPase mediated signal transduction(GO:0051057) |
0.0 | 0.4 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.0 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
0.0 | 0.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.4 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.0 | 0.0 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.1 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
0.0 | 0.1 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.0 | 0.2 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
0.0 | 0.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
0.0 | 0.1 | GO:0035799 | ureter maturation(GO:0035799) |
0.0 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.1 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
0.0 | 0.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.0 | 0.3 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.0 | 0.2 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
0.0 | 0.1 | GO:1904604 | connective tissue replacement involved in inflammatory response wound healing(GO:0002248) regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204) |
0.0 | 0.0 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
0.0 | 0.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.0 | 0.1 | GO:0006574 | valine catabolic process(GO:0006574) |
0.0 | 0.1 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.1 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
0.0 | 0.0 | GO:0060166 | olfactory pit development(GO:0060166) |
0.0 | 0.1 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
0.0 | 0.1 | GO:0045582 | positive regulation of T cell differentiation(GO:0045582) |
0.0 | 0.3 | GO:0072537 | fibroblast activation(GO:0072537) |
0.0 | 0.1 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.0 | 0.1 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.0 | 0.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.1 | GO:0051938 | regulation of amino acid import(GO:0010958) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) L-glutamate import(GO:0051938) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) amino acid import into cell(GO:1902837) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123) |
0.0 | 0.0 | GO:0042489 | negative regulation of odontogenesis of dentin-containing tooth(GO:0042489) |
0.0 | 0.2 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.0 | 0.3 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
0.0 | 0.8 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
0.0 | 0.1 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.0 | 0.1 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
0.0 | 0.2 | GO:0009304 | tRNA transcription(GO:0009304) |
0.0 | 0.8 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) |
0.0 | 0.1 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
0.0 | 0.0 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
0.0 | 0.2 | GO:0033033 | negative regulation of myeloid cell apoptotic process(GO:0033033) |
0.0 | 0.1 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.0 | 0.4 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
0.0 | 0.2 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.0 | 2.6 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
0.0 | 0.1 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.0 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
0.0 | 1.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
0.0 | 0.2 | GO:0015671 | oxygen transport(GO:0015671) |
0.0 | 0.2 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
0.0 | 1.0 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
0.0 | 0.3 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
0.0 | 0.2 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 0.1 | GO:0015677 | copper ion import(GO:0015677) |
0.0 | 0.5 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.0 | 0.1 | GO:0042428 | serotonin metabolic process(GO:0042428) |
0.0 | 0.1 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
0.0 | 0.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.0 | 0.1 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
0.0 | 1.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.1 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
0.0 | 0.2 | GO:0051601 | exocyst localization(GO:0051601) |
0.0 | 0.2 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
0.0 | 0.6 | GO:0007603 | phototransduction, visible light(GO:0007603) |
0.0 | 0.0 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
0.0 | 0.1 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.0 | 0.1 | GO:0032364 | oxygen homeostasis(GO:0032364) |
0.0 | 0.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.3 | GO:0032098 | regulation of appetite(GO:0032098) |
0.0 | 0.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
0.0 | 0.1 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.0 | 0.1 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.0 | 0.0 | GO:0002023 | reduction of food intake in response to dietary excess(GO:0002023) |
0.0 | 0.1 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.0 | 0.0 | GO:0006051 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
0.0 | 0.2 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
0.0 | 0.2 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 0.0 | GO:0044793 | negative regulation by host of viral process(GO:0044793) |
0.0 | 0.0 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
0.0 | 0.1 | GO:0042574 | retinal metabolic process(GO:0042574) |
0.0 | 0.6 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
0.0 | 0.2 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
0.0 | 0.0 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
0.0 | 0.6 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.1 | GO:0045023 | G0 to G1 transition(GO:0045023) |
0.0 | 0.0 | GO:0043615 | astrocyte cell migration(GO:0043615) |
0.0 | 0.0 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.0 | 0.1 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
0.0 | 0.1 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.0 | 0.2 | GO:0097178 | ruffle assembly(GO:0097178) |
0.0 | 0.2 | GO:0060850 | regulation of transcription involved in cell fate commitment(GO:0060850) |
0.0 | 0.4 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
0.0 | 0.1 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.0 | 0.1 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
0.0 | 0.0 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
0.0 | 0.0 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.0 | 0.1 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
0.0 | 0.2 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
0.0 | 0.1 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
0.0 | 0.0 | GO:0035701 | hematopoietic stem cell migration(GO:0035701) |
0.0 | 0.2 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
0.0 | 0.0 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
0.0 | 0.0 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
0.0 | 0.6 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.0 | 0.2 | GO:1903319 | positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319) |
0.0 | 0.1 | GO:0048298 | regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298) |
0.0 | 0.1 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
0.0 | 0.3 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.0 | 0.1 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.2 | 0.6 | GO:0005608 | laminin-3 complex(GO:0005608) |
0.2 | 0.2 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
0.2 | 0.5 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
0.2 | 2.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 3.0 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 2.5 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 0.7 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 0.3 | GO:0043159 | acrosomal matrix(GO:0043159) |
0.1 | 0.2 | GO:0030849 | autosome(GO:0030849) |
0.1 | 0.5 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.1 | 0.2 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.8 | GO:0097433 | dense body(GO:0097433) |
0.1 | 0.9 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.1 | 0.3 | GO:1990037 | Lewy body core(GO:1990037) |
0.1 | 0.2 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
0.1 | 0.1 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.1 | 0.4 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
0.1 | 0.2 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.1 | 0.2 | GO:0000126 | transcription factor TFIIIB complex(GO:0000126) |
0.0 | 0.2 | GO:0097196 | Shu complex(GO:0097196) |
0.0 | 1.1 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
0.0 | 1.5 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.3 | GO:0014802 | terminal cisterna(GO:0014802) |
0.0 | 0.4 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.0 | 0.5 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.0 | 0.7 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.0 | 0.3 | GO:0089701 | U2AF(GO:0089701) |
0.0 | 0.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 1.2 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
0.0 | 0.0 | GO:0005767 | secondary lysosome(GO:0005767) |
0.0 | 0.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.0 | 0.4 | GO:0036157 | outer dynein arm(GO:0036157) |
0.0 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.1 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
0.0 | 0.2 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.0 | 0.5 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 5.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 2.9 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 2.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.0 | 0.4 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
0.0 | 0.0 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.0 | 0.2 | GO:0070081 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
0.0 | 0.2 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
0.0 | 0.1 | GO:0005579 | membrane attack complex(GO:0005579) |
0.0 | 1.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.1 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
0.0 | 0.4 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.5 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 0.3 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 2.1 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.3 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 0.1 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.0 | 0.1 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.0 | 0.6 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.1 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.1 | GO:0097361 | CIA complex(GO:0097361) |
0.0 | 0.1 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.2 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.1 | GO:1990130 | Iml1 complex(GO:1990130) |
0.0 | 3.5 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 1.5 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.4 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.1 | GO:0097362 | MCM8-MCM9 complex(GO:0097362) |
0.0 | 0.1 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.0 | 0.2 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.1 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
0.0 | 0.3 | GO:0000242 | pericentriolar material(GO:0000242) |
0.0 | 0.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.0 | 0.3 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.0 | 0.1 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.5 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 1.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.5 | GO:0008305 | integrin complex(GO:0008305) |
0.0 | 2.1 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.1 | GO:0030663 | COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663) |
0.0 | 0.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 0.0 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.0 | 0.7 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.3 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.1 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.0 | 0.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.1 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.8 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 0.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.7 | GO:0015030 | Cajal body(GO:0015030) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.1 | GO:0047708 | biotinidase activity(GO:0047708) |
0.3 | 1.3 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
0.3 | 2.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
0.3 | 1.2 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
0.3 | 3.2 | GO:0031419 | cobalamin binding(GO:0031419) |
0.2 | 4.4 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
0.2 | 0.7 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
0.2 | 0.6 | GO:0042007 | interleukin-18 binding(GO:0042007) |
0.2 | 4.9 | GO:0070330 | aromatase activity(GO:0070330) |
0.2 | 0.6 | GO:0035034 | histone acetyltransferase regulator activity(GO:0035034) |
0.2 | 0.8 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
0.2 | 1.6 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.2 | 2.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
0.2 | 0.5 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.2 | 0.8 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.2 | 0.5 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.1 | 0.4 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
0.1 | 0.7 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.1 | 0.4 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
0.1 | 0.9 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
0.1 | 0.4 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
0.1 | 0.5 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
0.1 | 0.5 | GO:0004803 | transposase activity(GO:0004803) |
0.1 | 0.1 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
0.1 | 0.6 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
0.1 | 0.7 | GO:0045118 | azole transporter activity(GO:0045118) |
0.1 | 0.5 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
0.1 | 0.3 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
0.1 | 1.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 0.3 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
0.1 | 1.8 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.1 | 1.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.1 | 0.4 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
0.1 | 0.4 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.1 | 1.6 | GO:1990459 | transferrin receptor binding(GO:1990459) |
0.1 | 0.3 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
0.1 | 0.9 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 0.9 | GO:0030884 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
0.1 | 0.2 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
0.1 | 1.1 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
0.1 | 0.5 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.1 | 1.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.1 | 2.1 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.3 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
0.1 | 0.2 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
0.1 | 0.3 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
0.1 | 0.4 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.1 | 0.5 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.1 | 0.3 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 0.3 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.1 | 0.2 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
0.1 | 0.2 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
0.1 | 0.3 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.1 | 0.2 | GO:0003947 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947) |
0.1 | 0.2 | GO:0045518 | interleukin-22 receptor binding(GO:0045518) |
0.1 | 0.9 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.1 | 0.3 | GO:0051373 | FATZ binding(GO:0051373) |
0.1 | 0.2 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 0.2 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
0.1 | 0.4 | GO:0016403 | dimethylargininase activity(GO:0016403) |
0.1 | 0.4 | GO:0004522 | ribonuclease A activity(GO:0004522) |
0.1 | 0.5 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
0.1 | 0.2 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.1 | 0.4 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.1 | 0.3 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.1 | 0.2 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
0.1 | 1.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 0.2 | GO:0047726 | iron-cytochrome-c reductase activity(GO:0047726) |
0.1 | 0.2 | GO:0001026 | TFIIIB-type transcription factor activity(GO:0001026) |
0.0 | 0.2 | GO:0004040 | amidase activity(GO:0004040) |
0.0 | 0.3 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.0 | 0.1 | GO:0008124 | 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124) |
0.0 | 0.3 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
0.0 | 0.1 | GO:0030395 | lactose binding(GO:0030395) |
0.0 | 0.4 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
0.0 | 0.2 | GO:0036033 | mediator complex binding(GO:0036033) |
0.0 | 0.1 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.0 | 0.5 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.0 | 0.2 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
0.0 | 0.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.4 | GO:1901612 | cardiolipin binding(GO:1901612) |
0.0 | 0.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.0 | 1.3 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.0 | 0.7 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
0.0 | 0.2 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.0 | 0.2 | GO:0070363 | mitochondrial light strand promoter sense binding(GO:0070363) |
0.0 | 0.5 | GO:0098505 | single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) |
0.0 | 0.5 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.0 | 1.6 | GO:0015106 | bicarbonate transmembrane transporter activity(GO:0015106) |
0.0 | 0.1 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.0 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731) |
0.0 | 0.1 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
0.0 | 2.3 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 0.7 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.0 | 1.1 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.0 | 0.3 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
0.0 | 0.1 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.0 | 0.1 | GO:0097363 | protein O-GlcNAc transferase activity(GO:0097363) |
0.0 | 0.4 | GO:0004875 | complement receptor activity(GO:0004875) |
0.0 | 0.2 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.0 | 0.2 | GO:0050682 | AF-2 domain binding(GO:0050682) |
0.0 | 0.1 | GO:0035500 | MH2 domain binding(GO:0035500) |
0.0 | 0.1 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
0.0 | 0.1 | GO:0005503 | all-trans retinal binding(GO:0005503) |
0.0 | 0.4 | GO:0008517 | folic acid transporter activity(GO:0008517) |
0.0 | 0.1 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
0.0 | 0.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.1 | GO:0030107 | HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) |
0.0 | 0.6 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.0 | 0.4 | GO:0019864 | IgG binding(GO:0019864) |
0.0 | 0.4 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.0 | 0.1 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
0.0 | 0.1 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
0.0 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.3 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.0 | 0.1 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.0 | 0.1 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.0 | 0.1 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.0 | 0.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 0.1 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
0.0 | 0.3 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.0 | 0.1 | GO:1990254 | keratin filament binding(GO:1990254) |
0.0 | 0.1 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
0.0 | 0.3 | GO:0008142 | oxysterol binding(GO:0008142) |
0.0 | 0.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.0 | 0.8 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.2 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
0.0 | 0.3 | GO:0035381 | purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381) purinergic receptor activity(GO:0035586) |
0.0 | 0.6 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 0.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.0 | 0.1 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
0.0 | 1.0 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 0.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 0.3 | GO:0008035 | high-density lipoprotein particle binding(GO:0008035) |
0.0 | 0.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
0.0 | 0.1 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.0 | 0.1 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.0 | 1.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 0.3 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.2 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.0 | 0.1 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
0.0 | 0.2 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.0 | 0.3 | GO:0004568 | chitinase activity(GO:0004568) |
0.0 | 0.0 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
0.0 | 1.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.1 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.0 | 0.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
0.0 | 0.1 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
0.0 | 0.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.0 | 1.0 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 0.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.1 | GO:0005283 | sodium:amino acid symporter activity(GO:0005283) |
0.0 | 0.1 | GO:0090541 | MIT domain binding(GO:0090541) |
0.0 | 0.1 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.0 | 0.1 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
0.0 | 0.2 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
0.0 | 0.2 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
0.0 | 0.1 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
0.0 | 0.1 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.0 | 0.1 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
0.0 | 0.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.0 | 0.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.1 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
0.0 | 0.1 | GO:0005534 | galactose binding(GO:0005534) |
0.0 | 0.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.0 | 0.1 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
0.0 | 0.1 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.0 | 0.1 | GO:1904599 | advanced glycation end-product binding(GO:1904599) |
0.0 | 0.0 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.0 | 0.1 | GO:0052795 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
0.0 | 0.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.0 | 0.3 | GO:0048018 | receptor agonist activity(GO:0048018) |
0.0 | 0.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 1.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.0 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.1 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.0 | 0.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.0 | 0.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.0 | 0.1 | GO:0005499 | vitamin D binding(GO:0005499) |
0.0 | 0.1 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
0.0 | 0.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.0 | 0.0 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
0.0 | 0.1 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 0.2 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.0 | 0.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
0.0 | 0.1 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.1 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
0.0 | 0.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.0 | 0.1 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.0 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.1 | GO:0004985 | opioid receptor activity(GO:0004985) |
0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 0.0 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.4 | GO:0030515 | snoRNA binding(GO:0030515) |
0.0 | 0.2 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.0 | GO:0098808 | mRNA cap binding(GO:0098808) |
0.0 | 0.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.0 | 0.1 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.0 | 0.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
0.0 | 0.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.0 | 0.0 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
0.0 | 0.5 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.1 | GO:0034711 | inhibin binding(GO:0034711) |
0.0 | 0.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.2 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.0 | 0.1 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.0 | 0.1 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.0 | 0.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.1 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.4 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.5 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.1 | GO:0042834 | peptidoglycan binding(GO:0042834) |
0.0 | 0.0 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.0 | 0.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.0 | 0.1 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.2 | GO:0051787 | misfolded protein binding(GO:0051787) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.1 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
0.1 | 2.7 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.1 | 2.0 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 1.3 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 1.9 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 1.0 | PID_IL23_PATHWAY | IL23-mediated signaling events |
0.0 | 0.4 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 3.3 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.0 | 1.2 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 0.3 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.1 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.3 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.0 | 1.4 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.4 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.2 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 0.3 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 0.1 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.0 | 0.0 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
0.0 | 1.1 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.1 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
0.0 | 0.2 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 1.3 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 0.5 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.1 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.5 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.7 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.5 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 1.0 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 1.4 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 0.2 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 0.4 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.0 | 0.3 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.3 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.7 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 0.4 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.1 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.1 | 0.3 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.1 | 1.5 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.1 | 1.2 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 2.5 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.1 | 2.1 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.1 | 1.4 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.1 | 2.1 | REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
0.1 | 1.0 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |
0.1 | 1.1 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
0.1 | 3.7 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 1.2 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.1 | 2.6 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 1.8 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 2.5 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.6 | REACTOME_OPSINS | Genes involved in Opsins |
0.0 | 2.3 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 1.8 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.5 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 0.4 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.0 | 0.0 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.0 | 0.8 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.0 | 0.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.0 | 0.8 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.0 | 1.8 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.3 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.0 | 0.2 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 0.4 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 0.5 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.0 | 0.6 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
0.0 | 0.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 1.4 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.3 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 0.2 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.0 | 0.0 | REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
0.0 | 0.7 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 0.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.4 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.2 | REACTOME_PROSTANOID_LIGAND_RECEPTORS | Genes involved in Prostanoid ligand receptors |
0.0 | 1.3 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 0.0 | REACTOME_SIGNALING_BY_FGFR3_MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.0 | 0.5 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.3 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.0 | 0.4 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.0 | 0.3 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.0 | 0.7 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.1 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.4 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.0 | 0.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 0.4 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
0.0 | 0.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 0.4 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |