Motif ID: RUNX1_RUNX2

Z-value: 1.059

Transcription factors associated with RUNX1_RUNX2:

Gene SymbolEntrez IDGene Name
RUNX1 ENSG00000159216.14 RUNX1
RUNX2 ENSG00000124813.16 RUNX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RUNX2hg19_v2_chr6_+_45389893_45389914-0.537.2e-03Click!
RUNX1hg19_v2_chr21_-_36421401_36421462-0.377.5e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1_RUNX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_180018540 3.923 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr20_+_31870927 3.457 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr3_+_100328433 2.965 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr1_+_47264711 2.558 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1


cytochrome P450, family 4, subfamily B, polypeptide 1


chr19_-_41388657 2.024 ENST00000301146.4
ENST00000291764.3
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr17_+_1633755 1.658 ENST00000545662.1
WDR81
WD repeat domain 81
chr15_-_93632421 1.563 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr9_-_130635741 1.452 ENST00000223836.10
AK1
adenylate kinase 1
chr5_-_35938674 1.429 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr19_+_56989609 1.392 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr2_-_216257849 1.372 ENST00000456923.1
FN1
fibronectin 1
chr20_-_23967432 1.332 ENST00000286890.4
ENST00000278765.4
GGTLC1

gamma-glutamyltransferase light chain 1

chr19_-_9092018 1.194 ENST00000397910.4
MUC16
mucin 16, cell surface associated
chr6_+_32407619 1.171 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr19_+_56989485 1.162 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667-AS1






ZNF667 antisense RNA 1 (head to head)






chr17_-_1532106 1.158 ENST00000301335.5
ENST00000382147.4
SLC43A2

solute carrier family 43 (amino acid system L transporter), member 2

chr19_-_6720686 1.134 ENST00000245907.6
C3
complement component 3
chr1_+_196621156 1.064 ENST00000359637.2
CFH
complement factor H
chr4_+_89299994 1.064 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr21_-_36421626 1.013 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr21_-_36421535 1.006 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1


runt-related transcription factor 1


chr17_-_29641084 0.985 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr15_-_56757329 0.976 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr1_-_46642154 0.942 ENST00000540385.1
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr3_-_50383096 0.936 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr9_+_120466610 0.930 ENST00000394487.4
TLR4
toll-like receptor 4
chr15_+_84116106 0.913 ENST00000535412.1
ENST00000324537.5
SH3GL3

SH3-domain GRB2-like 3

chr6_-_165723088 0.911 ENST00000230301.8
C6orf118
chromosome 6 open reading frame 118
chr16_+_82068830 0.882 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr3_+_42947600 0.873 ENST00000328199.6
ENST00000541208.1
ZNF662

zinc finger protein 662

chr1_-_223536679 0.872 ENST00000608996.1
SUSD4
sushi domain containing 4
chr2_+_8822113 0.869 ENST00000396290.1
ENST00000331129.3
ID2

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

chr1_-_183622442 0.858 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr22_+_31003133 0.849 ENST00000405742.3
TCN2
transcobalamin II
chr22_+_31002779 0.847 ENST00000215838.3
TCN2
transcobalamin II
chr22_+_31003190 0.836 ENST00000407817.3
TCN2
transcobalamin II
chr1_+_196621002 0.827 ENST00000367429.4
ENST00000439155.2
CFH

complement factor H

chr12_-_8693469 0.826 ENST00000545274.1
ENST00000446457.2
CLEC4E

C-type lectin domain family 4, member E

chr2_+_132286754 0.819 ENST00000434330.1
CCDC74A
coiled-coil domain containing 74A
chr16_-_28608364 0.816 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr22_+_22988816 0.814 ENST00000480559.1
ENST00000448514.1
GGTLC2

gamma-glutamyltransferase light chain 2

chr17_+_73780852 0.806 ENST00000589666.1
UNK
unkempt family zinc finger
chr6_-_33048483 0.803 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr17_-_34417479 0.798 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr11_-_102401469 0.794 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr8_-_102803163 0.787 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr1_-_160231451 0.784 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr19_+_17982747 0.773 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr17_-_1531635 0.764 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr1_-_109655355 0.764 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr16_-_28621353 0.759 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_10686373 0.753 ENST00000442825.2
CLNK
cytokine-dependent hematopoietic cell linker
chr12_+_15125954 0.745 ENST00000266395.2
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr3_+_15643140 0.739 ENST00000449107.1
BTD
biotinidase
chr1_-_109655377 0.738 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr3_+_148508845 0.731 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr14_+_21359558 0.728 ENST00000304639.3
RNASE3
ribonuclease, RNase A family, 3
chr1_-_108743471 0.723 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_+_15643245 0.714 ENST00000303498.5
ENST00000437172.1
BTD

biotinidase

chr2_-_216300784 0.713 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chrX_-_44202857 0.707 ENST00000420999.1
EFHC2
EF-hand domain (C-terminal) containing 2
chr19_+_41497178 0.701 ENST00000324071.4
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr4_-_100356844 0.695 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_59633951 0.687 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr6_+_159071015 0.686 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr1_+_228870824 0.682 ENST00000366691.3
RHOU
ras homolog family member U
chr1_-_179112189 0.669 ENST00000512653.1
ENST00000344730.3
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr17_+_56232494 0.667 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr7_-_16921601 0.665 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3


anterior gradient 3


chr6_-_31745085 0.664 ENST00000375686.3
ENST00000447450.1
VWA7

von Willebrand factor A domain containing 7

chr3_-_150920979 0.664 ENST00000309180.5
ENST00000480322.1
GPR171

G protein-coupled receptor 171

chr22_+_25003626 0.661 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1


gamma-glutamyltransferase 1


chr1_+_32930647 0.657 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr10_+_114169299 0.656 ENST00000369410.3
ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_31745037 0.655 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr10_+_114135004 0.644 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_-_84035868 0.638 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr3_-_19975665 0.638 ENST00000295824.9
ENST00000389256.4
EFHB

EF-hand domain family, member B

chr14_-_65769392 0.637 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr9_+_120466650 0.635 ENST00000355622.6
TLR4
toll-like receptor 4
chr4_+_89299885 0.635 ENST00000380265.5
ENST00000273960.3
HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

chrX_+_53449887 0.634 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr17_+_79935464 0.631 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chr3_-_49170405 0.625 ENST00000305544.4
ENST00000494831.1
LAMB2

laminin, beta 2 (laminin S)

chr6_-_46889694 0.623 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116


G protein-coupled receptor 116


chr6_+_42847649 0.619 ENST00000424341.2
ENST00000602561.1
RPL7L1

ribosomal protein L7-like 1

chr14_-_94854926 0.618 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1


chr14_-_107078851 0.615 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr4_-_84035905 0.614 ENST00000311507.4
PLAC8
placenta-specific 8
chr17_+_79935418 0.608 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chrX_+_53449805 0.608 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr3_+_15643476 0.599 ENST00000436193.1
ENST00000383778.4
BTD

biotinidase

chr17_-_39183452 0.595 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr6_+_26365443 0.592 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chr19_+_3708376 0.583 ENST00000539908.2
TJP3
tight junction protein 3
chr11_+_124481361 0.581 ENST00000284288.2
PANX3
pannexin 3
chr14_-_23285069 0.579 ENST00000554758.1
ENST00000397528.4
SLC7A7

solute carrier family 7 (amino acid transporter light chain, y+L system), member 7

chr6_-_32920794 0.579 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA


XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha


Uncharacterized protein
chr20_-_33460621 0.577 ENST00000427420.1
ENST00000336431.5
GGT7

gamma-glutamyltransferase 7

chr7_+_120628731 0.575 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr4_-_10686475 0.575 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr1_-_157522260 0.573 ENST00000368191.3
ENST00000361835.3
FCRL5

Fc receptor-like 5

chr12_-_54121261 0.571 ENST00000549784.1
ENST00000262059.4
CALCOCO1

calcium binding and coiled-coil domain 1

chr16_-_28608424 0.568 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr19_+_54495542 0.568 ENST00000252729.2
ENST00000352529.1
CACNG6

calcium channel, voltage-dependent, gamma subunit 6

chr12_-_54121212 0.565 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1







calcium binding and coiled-coil domain 1







chr2_-_229046361 0.564 ENST00000392056.3
SPHKAP
SPHK1 interactor, AKAP domain containing
chr6_+_31895467 0.561 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr8_+_76452097 0.558 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chrX_+_9431324 0.557 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr21_+_42733870 0.556 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2


myxovirus (influenza virus) resistance 2 (mouse)


chr6_-_31846744 0.554 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
SLC44A4


solute carrier family 44, member 4


chr15_-_65503801 0.552 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr17_-_34524157 0.551 ENST00000378354.4
ENST00000394484.1
CCL3L3

chemokine (C-C motif) ligand 3-like 3

chr2_+_136499287 0.548 ENST00000415164.1
UBXN4
UBX domain protein 4
chr3_-_187454281 0.547 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr2_-_158300556 0.546 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr4_-_38806404 0.546 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr15_+_84115868 0.545 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr2_-_238499303 0.542 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr14_-_23285011 0.540 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_75988768 0.533 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr12_-_71551652 0.533 ENST00000546561.1
TSPAN8
tetraspanin 8
chr5_+_156696362 0.533 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_-_100356551 0.527 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr20_+_31749574 0.525 ENST00000253362.2
BPIFA2
BPI fold containing family A, member 2
chr16_+_53133070 0.520 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr20_+_37434329 0.519 ENST00000299824.1
ENST00000373331.2
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr13_+_113622757 0.514 ENST00000375604.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr11_+_6411670 0.514 ENST00000530395.1
ENST00000527275.1
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr7_-_99679324 0.512 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3






zinc finger protein 3






chr17_-_34625719 0.509 ENST00000422211.2
ENST00000542124.1
CCL3L1

chemokine (C-C motif) ligand 3-like 1

chr13_+_113622810 0.508 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_+_10541462 0.507 ENST00000293683.5
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_-_226129083 0.502 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr10_+_91092241 0.501 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr6_+_31916733 0.500 ENST00000483004.1
CFB
complement factor B
chrX_-_54209640 0.500 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C


family with sequence similarity 120C


chr6_-_56258892 0.497 ENST00000370819.1
COL21A1
collagen, type XXI, alpha 1
chr1_-_226129189 0.493 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr11_+_6411636 0.491 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chrX_-_2418936 0.488 ENST00000412516.2
ENST00000334651.5
ENST00000461691.1
ENST00000381223.4
ENST00000381222.2
DHRSX

ZBED1


dehydrogenase/reductase (SDR family) X-linked

zinc finger, BED-type containing 1


chr22_-_21580582 0.485 ENST00000424627.1
GGT2
gamma-glutamyltransferase 2
chr2_+_183943464 0.485 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr15_+_49170281 0.483 ENST00000560490.1
EID1
EP300 interacting inhibitor of differentiation 1
chr1_-_201096312 0.476 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr7_+_100612904 0.475 ENST00000379442.3
ENST00000536621.1
MUC12

mucin 12, cell surface associated

chr2_+_233527443 0.474 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr1_+_248031277 0.473 ENST00000537741.1
OR2W3
olfactory receptor, family 2, subfamily W, member 3
chr1_+_172628154 0.470 ENST00000340030.3
ENST00000367721.2
FASLG

Fas ligand (TNF superfamily, member 6)

chr5_-_42811986 0.470 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr1_-_235098935 0.466 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr11_-_62457371 0.466 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr11_+_101785727 0.464 ENST00000263468.8
KIAA1377
KIAA1377
chr2_-_74779744 0.464 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr10_+_91152303 0.464 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr3_+_113251143 0.463 ENST00000264852.4
ENST00000393830.3
SIDT1

SID1 transmembrane family, member 1

chr16_+_82090028 0.463 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr18_+_61575200 0.461 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr8_-_110704014 0.461 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU


syntabulin (syntaxin-interacting)


chr1_+_206643787 0.460 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr6_-_24911195 0.460 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr2_+_169659121 0.455 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN


nitric oxide synthase trafficking


chr8_-_110703819 0.454 ENST00000532779.1
ENST00000534578.1
SYBU

syntabulin (syntaxin-interacting)

chr4_-_70505358 0.454 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2


UDP glucuronosyltransferase 2 family, polypeptide A2


chr12_-_8693539 0.450 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr19_+_54496132 0.448 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr16_+_202686 0.444 ENST00000252951.2
HBZ
hemoglobin, zeta
chr19_-_52133588 0.444 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr16_+_2802623 0.443 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2



serine/arginine repetitive matrix 2



chr3_-_112218205 0.436 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr2_-_209010874 0.433 ENST00000260988.4
CRYGB
crystallin, gamma B
chr16_-_75590114 0.433 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
TMEM231


transmembrane protein 231


chr11_-_5345582 0.433 ENST00000328813.2
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr22_+_42665742 0.432 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3


Z83851.3


chr12_+_111051832 0.431 ENST00000550703.2
ENST00000551590.1
TCTN1

tectonic family member 1

chr17_-_42019836 0.429 ENST00000225992.3
PPY
pancreatic polypeptide
chr8_+_39770803 0.428 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr6_+_30951487 0.427 ENST00000486149.2
ENST00000376296.3
MUC21

mucin 21, cell surface associated

chr3_-_37034702 0.426 ENST00000322716.5
EPM2AIP1
EPM2A (laforin) interacting protein 1
chrX_-_128788914 0.426 ENST00000429967.1
ENST00000307484.6
APLN

apelin

chr3_+_98699880 0.423 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr20_-_3154162 0.422 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr6_-_39197226 0.420 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr1_-_168464875 0.419 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr12_+_111051902 0.417 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1



tectonic family member 1



chr11_+_61717336 0.417 ENST00000378042.3
BEST1
bestrophin 1
chr1_+_202976493 0.413 ENST00000367242.3
TMEM183A
transmembrane protein 183A
chrX_-_102319092 0.408 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr1_-_184006611 0.408 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr6_+_28109703 0.405 ENST00000457389.2
ENST00000330236.6
ZKSCAN8

zinc finger with KRAB and SCAN domains 8

chr9_+_34458771 0.404 ENST00000437363.1
ENST00000242317.4
DNAI1

dynein, axonemal, intermediate chain 1

chr5_-_38595498 0.404 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr6_+_32709119 0.404 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr11_+_61717279 0.403 ENST00000378043.4
BEST1
bestrophin 1
chr9_-_123342415 0.402 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
CDK5RAP2



CDK5 regulatory subunit associated protein 2



chr15_-_37393406 0.400 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr17_+_57408994 0.400 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr12_-_323689 0.398 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr12_+_93772326 0.397 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
NUDT4



nudix (nucleoside diphosphate linked moiety X)-type motif 4




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 1.6 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.5 3.5 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.4 1.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 2.6 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 1.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.3 3.2 GO:0015889 cobalamin transport(GO:0015889)
0.2 4.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 0.7 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.2 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.2 0.9 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.9 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2 1.1 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.2 0.5 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 1.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 4.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 0.5 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 0.5 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 0.2 GO:1902107 positive regulation of leukocyte differentiation(GO:1902107)
0.2 0.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.4 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.4 GO:0060545 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.6 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.4 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.9 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.4 GO:0072683 T cell extravasation(GO:0072683)
0.1 0.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.4 GO:0033214 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.1 3.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.4 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.3 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.7 GO:0061526 acetylcholine secretion(GO:0061526)
0.1 0.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 1.0 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.1 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 2.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 2.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.5 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.2 GO:0003064 regulation of heart rate by hormone(GO:0003064)
0.1 0.7 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 0.5 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.5 GO:0006768 biotin metabolic process(GO:0006768)
0.1 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 1.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 0.3 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.1 1.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:0015822 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.1 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.9 GO:0015866 ADP transport(GO:0015866)
0.1 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.4 GO:0045007 depurination(GO:0045007)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.3 GO:1904970 brush border assembly(GO:1904970)
0.1 0.6 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.2 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.2 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.0 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) spindle assembly involved in meiosis(GO:0090306)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.1 GO:0001562 response to protozoan(GO:0001562)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.5 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 1.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.5 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 1.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 1.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.6 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.2 GO:0071839 apoptotic process in bone marrow(GO:0071839)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.0 GO:0046545 development of primary female sexual characteristics(GO:0046545)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:1903644 regulation of protein folding(GO:1903332) regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.0 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.7 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.2 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.0 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.2 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:1904604 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.1 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.0 0.3 GO:0072537 fibroblast activation(GO:0072537)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0051938 regulation of amino acid import(GO:0010958) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) L-glutamate import(GO:0051938) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) amino acid import into cell(GO:1902837) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0 0.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.2 GO:0009304 tRNA transcription(GO:0009304)
0.0 0.8 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 2.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 1.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.6 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.0 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:1903319 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.1 GO:0048298 regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.6 GO:0005608 laminin-3 complex(GO:0005608)
0.2 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 3.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.5 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0097196 Shu complex(GO:0097196)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.0 GO:0005767 secondary lysosome(GO:0005767)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 5.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0047708 biotinidase activity(GO:0047708)
0.3 1.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 2.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.3 1.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 3.2 GO:0031419 cobalamin binding(GO:0031419)
0.2 4.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.7 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.2 0.6 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 4.9 GO:0070330 aromatase activity(GO:0070330)
0.2 0.6 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 0.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 1.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 2.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 0.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.5 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.5 GO:0004803 transposase activity(GO:0004803)
0.1 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.6 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.7 GO:0045118 azole transporter activity(GO:0045118)
0.1 0.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 0.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 1.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.9 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.3 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.2 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.2 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.2 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.2 GO:0004040 amidase activity(GO:0004040)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.5 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.6 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 2.3 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0035381 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381) purinergic receptor activity(GO:0035586)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.0 0.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 2.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.0 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 3.3 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 1.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.1 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.2 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.7 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.2 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 2.5 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.0 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.1 1.1 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.6 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_OPSINS Genes involved in Opsins
0.0 2.3 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.0 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.0 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.0 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis