Motif ID: RORC

Z-value: 0.389


Transcription factors associated with RORC:

Gene SymbolEntrez IDGene Name
RORC ENSG00000143365.12 RORC

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RORChg19_v2_chr1_-_151798546_1517985900.321.2e-01Click!


Activity profile for motif RORC.

activity profile for motif RORC


Sorted Z-values histogram for motif RORC

Sorted Z-values for motif RORC



Network of associatons between targets according to the STRING database.



First level regulatory network of RORC

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_4671352 0.577 ENST00000542744.1
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr12_+_7167980 0.405 ENST00000360817.5
ENST00000402681.3
C1S

complement component 1, s subcomponent

chr8_+_71485681 0.384 ENST00000391684.1
AC120194.1
AC120194.1
chr17_-_46623441 0.336 ENST00000330070.4
HOXB2
homeobox B2
chr12_+_93963590 0.250 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr19_+_38924316 0.249 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1


ryanodine receptor 1 (skeletal)


chr12_+_93964158 0.246 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chrX_-_102531717 0.240 ENST00000372680.1
TCEAL5
transcription elongation factor A (SII)-like 5
chr1_+_104198377 0.238 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr3_-_45957088 0.223 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr3_-_45957534 0.186 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr19_-_49140609 0.178 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_10450287 0.161 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3



intercellular adhesion molecule 3



chr16_-_1821496 0.157 ENST00000564628.1
ENST00000563498.1
NME3

NME/NM23 nucleoside diphosphate kinase 3

chrX_-_43832711 0.146 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr9_-_110251836 0.138 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr19_-_49140692 0.132 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr3_+_160559931 0.125 ENST00000464260.1
ENST00000295839.9
PPM1L

protein phosphatase, Mg2+/Mn2+ dependent, 1L

chr20_-_23433494 0.121 ENST00000377007.3
CST11
cystatin 11
chr10_-_21435488 0.121 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113


chromosome 10 open reading frame 113



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)

Gene overrepresentation in cellular_component category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate