Motif ID: RELA
Z-value: 1.244

Transcription factors associated with RELA:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
RELA | ENSG00000173039.14 | RELA |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
RELA | hg19_v2_chr11_-_65430251_65430399 | 0.55 | 5.5e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 129 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 8.4 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.5 | 4.4 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
1.4 | 4.1 | GO:0045360 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
1.2 | 3.6 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
0.1 | 3.3 | GO:0071498 | cellular response to fluid shear stress(GO:0071498) |
0.3 | 3.0 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
0.1 | 3.0 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
0.0 | 2.8 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
0.6 | 2.5 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
0.1 | 2.4 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
0.1 | 2.1 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
0.3 | 2.0 | GO:0060005 | vestibular reflex(GO:0060005) |
0.1 | 2.0 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
0.1 | 1.9 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
0.4 | 1.8 | GO:0044501 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
0.2 | 1.8 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
0.1 | 1.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.6 | 1.7 | GO:0070428 | B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
0.6 | 1.7 | GO:0045210 | FasL biosynthetic process(GO:0045210) |
0.0 | 1.7 | GO:0060113 | inner ear receptor cell differentiation(GO:0060113) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 51 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 21.0 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 7.8 | GO:0045121 | membrane raft(GO:0045121) |
0.0 | 4.0 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 3.8 | GO:0005901 | caveola(GO:0005901) |
0.6 | 2.5 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
0.2 | 2.5 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 2.4 | GO:0002102 | podosome(GO:0002102) |
0.1 | 2.1 | GO:0045180 | basal cortex(GO:0045180) |
0.2 | 1.8 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.0 | 1.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 1.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.4 | 1.6 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
0.2 | 1.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 1.4 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 1.4 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
0.0 | 1.4 | GO:0000145 | exocyst(GO:0000145) |
0.4 | 1.3 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
0.1 | 1.3 | GO:0033643 | host cell part(GO:0033643) |
0.0 | 1.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.9 | GO:0036449 | microtubule minus-end(GO:0036449) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 86 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 11.0 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 8.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 4.2 | GO:0003924 | GTPase activity(GO:0003924) |
1.4 | 4.1 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
0.9 | 3.6 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.0 | 3.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 2.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.5 | 2.4 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
0.1 | 2.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.1 | 2.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 2.1 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 2.1 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.1 | 2.0 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.1 | 2.0 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.1 | 1.9 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.2 | 1.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 1.6 | GO:0008199 | ferric iron binding(GO:0008199) |
0.0 | 1.6 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.2 | 1.4 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
0.0 | 1.4 | GO:0001618 | virus receptor activity(GO:0001618) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 33 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 11.4 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.2 | 10.9 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.1 | 8.5 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 3.6 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.1 | 3.2 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 3.2 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.1 | 2.9 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 2.9 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 2.0 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.0 | 2.0 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.1 | 1.8 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 1.7 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
0.0 | 1.6 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
0.0 | 1.5 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.1 | 1.4 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.0 | 1.2 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 1.2 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
0.0 | 1.2 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 1.2 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 1.1 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 38 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 16.0 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.2 | 7.5 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.1 | 5.1 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.1 | 3.6 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 3.6 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.1 | 2.7 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.1 | 2.3 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.1 | 2.3 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 2.2 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 2.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 1.9 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 1.6 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 1.6 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 1.6 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.1 | 1.5 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 1.5 | REACTOME_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell junction organization |
0.1 | 1.0 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
0.0 | 1.0 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.0 | 1.0 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 0.9 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |