Motif ID: PRDM14

Z-value: 0.244


Transcription factors associated with PRDM14:

Gene SymbolEntrez IDGene Name
PRDM14 ENSG00000147596.3 PRDM14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRDM14hg19_v2_chr8_-_70983506_70983562-0.019.5e-01Click!


Activity profile for motif PRDM14.

activity profile for motif PRDM14


Sorted Z-values histogram for motif PRDM14

Sorted Z-values for motif PRDM14



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM14

PNG image of the network

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Top targets:


Showing 1 to 20 of 81 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_55866997 0.443 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr4_-_103266626 0.195 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr2_+_101437487 0.149 ENST00000427413.1
ENST00000542504.1
NPAS2

neuronal PAS domain protein 2

chr2_-_69098566 0.148 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr19_+_49838653 0.134 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37





CD37 molecule





chr12_-_49351228 0.116 ENST00000541959.1
ENST00000447318.2
ARF3

ADP-ribosylation factor 3

chrX_+_41193407 0.115 ENST00000457138.2
ENST00000441189.2
DDX3X

DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked

chr12_-_49351148 0.093 ENST00000539611.1
ENST00000398092.4
ARF3
RP11-302B13.5
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr17_-_46691990 0.088 ENST00000576562.1
HOXB8
homeobox B8
chrX_+_15525426 0.088 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr7_-_139763521 0.083 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr12_-_49351303 0.083 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr6_-_46048116 0.080 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr17_+_41924511 0.075 ENST00000377203.4
ENST00000539718.1
ENST00000588884.1
ENST00000293396.8
ENST00000586233.1
CD300LG




CD300 molecule-like family member g




chr12_+_56325812 0.075 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA





diacylglycerol kinase, alpha 80kDa





chr9_+_132099158 0.074 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr20_-_3154162 0.073 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr17_-_46692287 0.072 ENST00000239144.4
HOXB8
homeobox B8
chrX_+_119292467 0.071 ENST00000371388.3
RHOXF2
Rhox homeobox family, member 2
chr1_+_36621529 0.071 ENST00000316156.4
MAP7D1
MAP7 domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)

Gene overrepresentation in molecular_function category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane