Motif ID: POU6F1

Z-value: 0.428


Transcription factors associated with POU6F1:

Gene SymbolEntrez IDGene Name
POU6F1 ENSG00000184271.11 POU6F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v2_chr12_-_51611477_516116120.048.4e-01Click!


Activity profile for motif POU6F1.

activity profile for motif POU6F1


Sorted Z-values histogram for motif POU6F1

Sorted Z-values for motif POU6F1



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151646800 1.214 ENST00000354675.6
 AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_153123345 0.799 ENST00000368748.4
 SPRR2G
small proline-rich protein 2G
chr1_-_197115818 0.553 ENST00000367409.4
ENST00000294732.7
 ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr2_+_128403720 0.519 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr2_+_128403439 0.514 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr8_+_39792474 0.498 ENST00000502986.2
 IDO2
indoleamine 2,3-dioxygenase 2
chr12_-_30887948 0.484 ENST00000433722.2
 CAPRIN2
caprin family member 2
chr9_+_128509624 0.483 ENST00000342287.5
ENST00000373487.4
 PBX3

pre-B-cell leukemia homeobox 3

chr8_+_118147498 0.472 ENST00000519688.1
ENST00000456015.2
 SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr6_-_110501200 0.455 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
 WASF1




WAS protein family, member 1




chr6_+_29274403 0.451 ENST00000377160.2
 OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr2_+_191045656 0.450 ENST00000443551.2
 C2orf88
chromosome 2 open reading frame 88
chr13_+_107029084 0.425 ENST00000444865.1
 LINC00460
long intergenic non-protein coding RNA 460
chr2_+_191045562 0.409 ENST00000340623.4
 C2orf88
chromosome 2 open reading frame 88
chr7_-_83824169 0.396 ENST00000265362.4
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_115219171 0.352 ENST00000409163.1
 DPP10
dipeptidyl-peptidase 10 (non-functional)
chr20_-_50419055 0.338 ENST00000217086.4
 SALL4
spalt-like transcription factor 4
chr12_+_102514019 0.327 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
 PARPBP


PARP1 binding protein


chr12_+_15699286 0.312 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
 PTPRO



protein tyrosine phosphatase, receptor type, O



chr3_+_46395219 0.299 ENST00000445132.2
ENST00000292301.4
 CCR2

chemokine (C-C motif) receptor 2

chr11_-_107729887 0.291 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr16_+_15744078 0.290 ENST00000396354.1
ENST00000570727.1
 NDE1

nudE neurodevelopment protein 1

chr12_+_102513950 0.277 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
 PARPBP



PARP1 binding protein



chr1_-_47655686 0.258 ENST00000294338.2
 PDZK1IP1
PDZK1 interacting protein 1
chr22_-_32767017 0.249 ENST00000400234.1
 RFPL3S
RFPL3 antisense
chr8_-_10512569 0.246 ENST00000382483.3
 RP1L1
retinitis pigmentosa 1-like 1
chr11_-_2323089 0.239 ENST00000456145.2
 C11orf21
chromosome 11 open reading frame 21
chr6_+_25754927 0.233 ENST00000377905.4
ENST00000439485.2
 SLC17A4

solute carrier family 17, member 4

chr15_-_31283618 0.226 ENST00000563714.1
 MTMR10
myotubularin related protein 10
chr4_+_106631966 0.211 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
 GSTCD


glutathione S-transferase, C-terminal domain containing


chr16_-_58718611 0.198 ENST00000564100.1
ENST00000570101.1
 SLC38A7

solute carrier family 38, member 7

chr7_-_38407770 0.197 ENST00000390348.2
 TRGV1
T cell receptor gamma variable 1 (non-functional)
chr19_+_52076425 0.191 ENST00000436511.2
 ZNF175
zinc finger protein 175
chr2_+_202937972 0.189 ENST00000541917.1
ENST00000295844.3
 AC079354.1

uncharacterized protein KIAA2012

chr1_+_225140372 0.171 ENST00000366848.1
ENST00000439375.2
 DNAH14

dynein, axonemal, heavy chain 14

chr2_-_166060571 0.167 ENST00000360093.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr2_-_166060552 0.162 ENST00000283254.7
ENST00000453007.1
 SCN3A

sodium channel, voltage-gated, type III, alpha subunit

chr13_+_107028897 0.162 ENST00000439790.1
ENST00000435024.1
 LINC00460

long intergenic non-protein coding RNA 460

chr6_+_26183958 0.161 ENST00000356530.3
 HIST1H2BE
histone cluster 1, H2be
chr4_+_78829479 0.160 ENST00000504901.1
 MRPL1
mitochondrial ribosomal protein L1
chr5_+_115177178 0.154 ENST00000316788.7
 AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr7_+_141490017 0.153 ENST00000247883.4
 TAS2R5
taste receptor, type 2, member 5
chr13_+_98612446 0.148 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
 IPO5


importin 5


chr4_+_110749143 0.139 ENST00000317735.4
 RRH
retinal pigment epithelium-derived rhodopsin homolog
chr1_-_243326612 0.138 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
 CEP170


centrosomal protein 170kDa


chr2_-_99917639 0.133 ENST00000308528.4
 LYG1
lysozyme G-like 1
chr16_-_87351022 0.130 ENST00000253461.4
 C16orf95
chromosome 16 open reading frame 95
chr1_+_225117350 0.130 ENST00000413949.2
ENST00000430092.1
ENST00000366850.3
ENST00000400952.3
ENST00000366849.1
 DNAH14




dynein, axonemal, heavy chain 14




chr12_+_10460417 0.123 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
 KLRD1


killer cell lectin-like receptor subfamily D, member 1


chr9_-_131644306 0.123 ENST00000302586.3
 CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr22_-_22307199 0.120 ENST00000397495.4
ENST00000263212.5
 PPM1F

protein phosphatase, Mg2+/Mn2+ dependent, 1F

chr11_-_4414880 0.119 ENST00000254436.7
ENST00000543625.1
 TRIM21

tripartite motif containing 21

chr16_-_87350970 0.117 ENST00000567970.1
 C16orf95
chromosome 16 open reading frame 95
chr1_-_106161540 0.117 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
 RP11-251P6.1


RP11-251P6.1


chr18_+_61554932 0.115 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr2_+_11679963 0.112 ENST00000263834.5
 GREB1
growth regulation by estrogen in breast cancer 1
chr9_-_131644202 0.103 ENST00000320665.6
ENST00000436267.2
 CCBL1

cysteine conjugate-beta lyase, cytoplasmic

chr1_+_113010056 0.094 ENST00000369686.5
 WNT2B
wingless-type MMTV integration site family, member 2B
chr11_-_65149422 0.093 ENST00000526432.1
ENST00000527174.1
 SLC25A45

solute carrier family 25, member 45

chrX_+_43515467 0.093 ENST00000338702.3
ENST00000542639.1
 MAOA

monoamine oxidase A

chr12_-_7596735 0.092 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
 CD163L1


CD163 molecule-like 1


chr13_+_58206655 0.092 ENST00000377918.3
 PCDH17
protocadherin 17
chr3_-_108248169 0.087 ENST00000273353.3
 MYH15
myosin, heavy chain 15
chr11_+_49050504 0.087 ENST00000332682.7
 TRIM49B
tripartite motif containing 49B
chr3_+_77088989 0.085 ENST00000461745.1
 ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr1_+_176432298 0.081 ENST00000367661.3
ENST00000367662.3
 PAPPA2

pappalysin 2

chr12_+_54892550 0.080 ENST00000545638.2
 NCKAP1L
NCK-associated protein 1-like
chr1_+_171107241 0.079 ENST00000236166.3
 FMO6P
flavin containing monooxygenase 6 pseudogene
chr1_-_89641680 0.075 ENST00000294671.2
 GBP7
guanylate binding protein 7
chr2_+_207220463 0.070 ENST00000598562.1
 AC017081.1
Uncharacterized protein
chr13_+_30510003 0.064 ENST00000400540.1
 LINC00544
long intergenic non-protein coding RNA 544
chr4_+_113970772 0.064 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
 ANK2



ankyrin 2, neuronal



chr17_-_40337470 0.064 ENST00000293330.1
 HCRT
hypocretin (orexin) neuropeptide precursor
chr11_+_2323349 0.061 ENST00000381121.3
 TSPAN32
tetraspanin 32
chr9_-_13165457 0.060 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
 MPDZ


multiple PDZ domain protein


chr15_+_80351977 0.060 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
 ZFAND6



zinc finger, AN1-type domain 6



chr4_-_169401628 0.059 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
 DDX60L




DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like




chr6_+_50786414 0.055 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
 TFAP2B


transcription factor AP-2 beta (activating enhancer binding protein 2 beta)


chr17_-_39165366 0.055 ENST00000391588.1
 KRTAP3-1
keratin associated protein 3-1
chr6_+_42123141 0.051 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
 GUCA1A



RP1-139D8.6
guanylate cyclase activator 1A (retina)



RP1-139D8.6
chr7_+_148287657 0.051 ENST00000307003.2
 C7orf33
chromosome 7 open reading frame 33
chr9_+_131644398 0.051 ENST00000372599.3
 LRRC8A
leucine rich repeat containing 8 family, member A
chr4_-_120222076 0.049 ENST00000504110.1
 C4orf3
chromosome 4 open reading frame 3
chr13_+_49551020 0.049 ENST00000541916.1
 FNDC3A
fibronectin type III domain containing 3A
chrX_+_119737806 0.046 ENST00000371317.5
 MCTS1
malignant T cell amplified sequence 1
chr9_+_131644388 0.045 ENST00000372600.4
 LRRC8A
leucine rich repeat containing 8 family, member A
chr12_-_95397442 0.045 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
 NDUFA12


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12


chr4_+_130692778 0.039 ENST00000513875.1
ENST00000508724.1
 RP11-422J15.1

RP11-422J15.1

chr12_-_108954933 0.037 ENST00000431469.2
ENST00000546815.1
 SART3

squamous cell carcinoma antigen recognized by T cells 3

chr10_-_43904235 0.035 ENST00000356053.3
 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr15_+_80351910 0.034 ENST00000261749.6
ENST00000561060.1
 ZFAND6

zinc finger, AN1-type domain 6

chr11_+_85339623 0.032 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
 TMEM126B



transmembrane protein 126B



chr12_-_108955070 0.029 ENST00000228284.3
ENST00000546611.1
 SART3

squamous cell carcinoma antigen recognized by T cells 3

chr19_-_3786253 0.028 ENST00000585778.1
 MATK
megakaryocyte-associated tyrosine kinase
chr4_+_123161120 0.026 ENST00000446180.1
 KIAA1109
KIAA1109
chr19_-_58662139 0.026 ENST00000598312.1
 ZNF329
zinc finger protein 329
chr17_-_39677971 0.023 ENST00000393976.2
 KRT15
keratin 15
chr19_-_3786354 0.022 ENST00000395040.2
ENST00000310132.6
 MATK

megakaryocyte-associated tyrosine kinase

chrX_-_100129128 0.020 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
 NOX1


NADPH oxidase 1


chr11_-_65381643 0.020 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
 MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr15_-_85259360 0.017 ENST00000559729.1
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr1_-_21377383 0.015 ENST00000374935.3
 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr6_-_138539627 0.015 ENST00000527246.2
 PBOV1
prostate and breast cancer overexpressed 1
chr8_-_146176199 0.015 ENST00000532351.1
ENST00000276816.4
ENST00000394909.2
 ZNF16


zinc finger protein 16


chr11_+_2323236 0.013 ENST00000182290.4
 TSPAN32
tetraspanin 32
chr10_+_97803151 0.009 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
 CCNJ



cyclin J



chr4_-_76912070 0.009 ENST00000395711.4
ENST00000356260.5
 SDAD1

SDA1 domain containing 1

chr20_-_50418972 0.008 ENST00000395997.3
 SALL4
spalt-like transcription factor 4
chr1_-_153538292 0.007 ENST00000497140.1
ENST00000368708.3
 S100A2

S100 calcium binding protein A2

chr20_-_50418947 0.003 ENST00000371539.3
 SALL4
spalt-like transcription factor 4
chr13_-_52027134 0.001 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6




integrator complex subunit 6




chr15_-_85259294 0.000 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
 SEC11A


SEC11 homolog A (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:1902567 negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:0048880 sensory system development(GO:0048880)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 1.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters