Motif ID: POU2F2_POU3F1

Z-value: 1.050

Transcription factors associated with POU2F2_POU3F1:

Gene SymbolEntrez IDGene Name
POU2F2 ENSG00000028277.16 POU2F2
POU3F1 ENSG00000185668.5 POU3F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636617_42636632-0.145.0e-01Click!
POU3F1hg19_v2_chr1_-_38512450_385124740.087.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_107078851 3.184 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr1_-_149858227 2.787 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr9_-_75567962 2.672 ENST00000297785.3
ENST00000376939.1
ALDH1A1

aldehyde dehydrogenase 1 family, member A1

chr3_+_63638339 2.538 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr6_+_26124373 2.228 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr5_+_36608422 2.056 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_44124019 1.929 ENST00000300811.3
ZNF428
zinc finger protein 428
chr6_+_26217159 1.799 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr16_+_23847267 1.773 ENST00000321728.7
PRKCB
protein kinase C, beta
chr9_-_84303269 1.703 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr14_+_79745746 1.699 ENST00000281127.7
NRXN3
neurexin 3
chr6_+_27833034 1.658 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr16_-_21314360 1.654 ENST00000219599.3
ENST00000576703.1
CRYM

crystallin, mu

chr1_-_183622442 1.609 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr18_-_53089723 1.498 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr6_-_52668605 1.483 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr14_-_106926724 1.433 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr19_-_17516449 1.384 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr6_+_27100811 1.369 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr9_+_136325089 1.351 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chr9_+_92219919 1.345 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr11_+_27062272 1.310 ENST00000529202.1
ENST00000533566.1
BBOX1

butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

chr6_-_27100529 1.302 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr6_-_26124138 1.295 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr11_+_27062860 1.268 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_+_27114861 1.266 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr11_+_27062502 1.264 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_44123734 1.257 ENST00000598676.1
ZNF428
zinc finger protein 428
chr6_-_26216872 1.235 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr16_+_33020496 1.203 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr17_-_73775839 1.187 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B




H3 histone, family 3B (H3.3B)




chrX_-_48776292 1.184 ENST00000376509.4
PIM2
pim-2 oncogene
chr1_-_149814478 1.181 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr1_+_149822620 1.157 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr17_+_72733350 1.153 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37


RAB37, member RAS oncogene family


chr1_+_149858461 1.152 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr11_+_27076764 1.119 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_-_33647696 1.108 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9

Uncharacterized protein

chr12_+_49297899 1.090 ENST00000552942.1
ENST00000320516.4
CCDC65

coiled-coil domain containing 65

chr16_-_30107491 1.070 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chr2_-_239148599 1.044 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6






hes family bHLH transcription factor 6






chr2_+_10861775 1.001 ENST00000272238.4
ENST00000381661.3
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr14_-_106845789 0.971 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr7_-_100183742 0.954 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr14_-_106622419 0.940 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr8_+_56792355 0.919 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr11_+_120107344 0.912 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr1_+_104198377 0.909 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr6_-_55739542 0.907 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr8_+_56792377 0.809 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_-_27860956 0.809 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr16_+_19429018 0.779 ENST00000542583.2
TMC5
transmembrane channel-like 5
chr1_-_154832316 0.775 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr12_-_68696652 0.763 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr1_+_167298281 0.763 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr18_-_52989525 0.762 ENST00000457482.3
TCF4
transcription factor 4
chr16_+_3019552 0.753 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr18_-_52989217 0.751 ENST00000570287.2
TCF4
transcription factor 4
chr1_+_61547894 0.749 ENST00000403491.3
NFIA
nuclear factor I/A
chr1_+_225600404 0.747 ENST00000366845.2
AC092811.1
AC092811.1
chr14_+_65007177 0.742 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr17_+_14204389 0.738 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_+_27782788 0.715 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr6_-_26033796 0.697 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr17_-_19651668 0.689 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr6_-_82462425 0.686 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr1_+_201979645 0.666 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr1_-_227505289 0.642 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr1_+_59775752 0.641 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr19_-_46088068 0.641 ENST00000263275.4
ENST00000323060.3
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr6_+_27861190 0.635 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr16_+_3019246 0.625 ENST00000318782.8
ENST00000293978.8
PAQR4

progestin and adipoQ receptor family member IV

chr12_-_7245125 0.623 ENST00000542285.1
ENST00000540610.1
C1R

complement component 1, r subcomponent

chr6_-_27114577 0.591 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr17_+_72426891 0.588 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_+_49297887 0.587 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr5_-_66492562 0.568 ENST00000256447.4
CD180
CD180 molecule
chr1_+_61547405 0.562 ENST00000371189.4
NFIA
nuclear factor I/A
chr1_+_228645796 0.560 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chr19_+_17337406 0.559 ENST00000597836.1
OCEL1
occludin/ELL domain containing 1
chr18_-_61311485 0.558 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4


serpin peptidase inhibitor, clade B (ovalbumin), member 4


chr17_+_38171614 0.557 ENST00000583218.1
ENST00000394149.3
CSF3

colony stimulating factor 3 (granulocyte)

chr12_+_122064673 0.556 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr3_-_148939835 0.554 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr15_-_20193370 0.553 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_211036051 0.552 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chr12_+_7052974 0.552 ENST00000544681.1
ENST00000537087.1
C12orf57

chromosome 12 open reading frame 57

chr2_-_172750733 0.547 ENST00000392592.4
ENST00000422440.2
SLC25A12

solute carrier family 25 (aspartate/glutamate carrier), member 12

chrX_+_69674943 0.546 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr21_+_10862622 0.536 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1

immunoglobulin heavy variable 1/OR21-1 (non-functional)

chr14_-_106610852 0.528 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr12_+_7053228 0.525 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chrX_+_80457442 0.522 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr17_-_19651654 0.516 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr7_+_90338712 0.508 ENST00000265741.3
ENST00000406263.1
CDK14

cyclin-dependent kinase 14

chr17_+_20059302 0.508 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_-_149783914 0.507 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF


histone cluster 2, H2bf


chr6_-_27775694 0.503 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr17_+_38171681 0.502 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3



colony stimulating factor 3 (granulocyte)



chr6_+_26158343 0.499 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr19_-_19144243 0.499 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2



SURP and G patch domain containing 2



chr14_+_103573853 0.493 ENST00000560304.1
EXOC3L4
exocyst complex component 3-like 4
chr11_-_5248294 0.491 ENST00000335295.4
HBB
hemoglobin, beta
chr7_-_112727774 0.489 ENST00000297146.3
ENST00000501255.2
GPR85

G protein-coupled receptor 85

chr12_-_100656134 0.486 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr12_+_7053172 0.486 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr1_-_6052463 0.483 ENST00000378156.4
NPHP4
nephronophthisis 4
chr19_+_41305085 0.477 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr17_+_68100989 0.473 ENST00000585558.1
ENST00000392670.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr19_-_40931891 0.473 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr11_-_62359027 0.470 ENST00000494385.1
ENST00000308436.7
TUT1

terminal uridylyl transferase 1, U6 snRNA-specific

chr14_-_107013465 0.469 ENST00000390625.2
IGHV3-49
immunoglobulin heavy variable 3-49
chr7_-_130080977 0.468 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr21_+_17566643 0.466 ENST00000419952.1
ENST00000445461.2
LINC00478

long intergenic non-protein coding RNA 478

chr11_+_537494 0.466 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr6_+_26183958 0.465 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr6_+_10585979 0.454 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_+_97010424 0.447 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
FHL5


four and a half LIM domains 5


chr5_+_73109339 0.440 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr2_+_97426631 0.439 ENST00000377075.2
CNNM4
cyclin M4
chr18_+_44526786 0.438 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr12_-_31479107 0.435 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr1_+_61542922 0.429 ENST00000407417.3
NFIA
nuclear factor I/A
chr14_-_107211459 0.427 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr2_-_158182410 0.425 ENST00000419116.2
ENST00000410096.1
ERMN

ermin, ERM-like protein

chr19_+_1269324 0.423 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP










cold inducible RNA binding protein










chr14_-_106518922 0.418 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr12_-_56359802 0.410 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
PMEL





premelanosome protein





chr2_-_89399845 0.408 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr20_+_33292068 0.401 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr7_-_27239703 0.395 ENST00000222753.4
HOXA13
homeobox A13
chr4_-_110223799 0.395 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
COL25A1


collagen, type XXV, alpha 1


chr14_+_62585332 0.395 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr18_-_53253112 0.395 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr1_-_23886285 0.394 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr15_+_84115868 0.394 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr19_+_17337007 0.391 ENST00000215061.4
OCEL1
occludin/ELL domain containing 1
chr5_-_19988339 0.391 ENST00000382275.1
CDH18
cadherin 18, type 2
chr18_-_74839891 0.389 ENST00000581878.1
MBP
myelin basic protein
chr16_-_55909255 0.382 ENST00000290567.9
CES5A
carboxylesterase 5A
chr16_-_55909272 0.381 ENST00000319165.9
CES5A
carboxylesterase 5A
chr16_-_19897455 0.380 ENST00000568214.1
ENST00000569479.1
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr4_-_25865159 0.379 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr6_-_55740352 0.376 ENST00000370830.3
BMP5
bone morphogenetic protein 5
chr6_-_26043885 0.376 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr2_-_239197201 0.374 ENST00000254658.3
PER2
period circadian clock 2
chr10_-_129691195 0.369 ENST00000368671.3
CLRN3
clarin 3
chr16_-_55909211 0.369 ENST00000520435.1
CES5A
carboxylesterase 5A
chr9_-_140196703 0.368 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr17_-_61850894 0.366 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chr9_-_116065551 0.366 ENST00000297894.5
RNF183
ring finger protein 183
chr17_+_57642886 0.366 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40




DEAH (Asp-Glu-Ala-His) box polypeptide 40




chrX_+_72667090 0.365 ENST00000373514.2
CDX4
caudal type homeobox 4
chr4_-_74088800 0.357 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr22_+_32750872 0.356 ENST00000397468.1
RFPL3
ret finger protein-like 3
chr14_-_106725723 0.356 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr19_+_17337473 0.354 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr17_+_61851504 0.353 ENST00000359353.5
ENST00000389924.2
DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

chr2_+_220143989 0.350 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr3_-_55001115 0.349 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr19_+_17337027 0.347 ENST00000601529.1
ENST00000600232.1
OCEL1

occludin/ELL domain containing 1

chr4_-_157892167 0.346 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr22_+_22764088 0.345 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr6_-_143266297 0.343 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr1_+_210406121 0.342 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr15_-_41166414 0.342 ENST00000220507.4
RHOV
ras homolog family member V
chr5_-_111091948 0.336 ENST00000447165.2
NREP
neuronal regeneration related protein
chr2_-_239197238 0.335 ENST00000254657.3
PER2
period circadian clock 2
chr6_+_148663729 0.331 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr9_-_124991124 0.322 ENST00000394319.4
ENST00000340587.3
LHX6

LIM homeobox 6

chr12_-_10955226 0.321 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr12_-_58212487 0.319 ENST00000549994.1
AVIL
advillin
chr15_+_84116106 0.318 ENST00000535412.1
ENST00000324537.5
SH3GL3

SH3-domain GRB2-like 3

chr9_+_35658377 0.317 ENST00000378409.3
CCDC107
coiled-coil domain containing 107
chr7_-_120498357 0.316 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chr17_+_73521763 0.316 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)




chr17_+_61851157 0.316 ENST00000578681.1
ENST00000583590.1
DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

chr11_+_74699703 0.311 ENST00000529024.1
ENST00000544263.1
NEU3

sialidase 3 (membrane sialidase)

chr18_-_30716038 0.309 ENST00000581852.1
CCDC178
coiled-coil domain containing 178
chr11_-_34379546 0.303 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr8_-_10512569 0.297 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr3_+_186435137 0.296 ENST00000447445.1
KNG1
kininogen 1
chr12_-_31479045 0.296 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr16_-_73082274 0.295 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr7_+_129932974 0.295 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr1_+_28099683 0.295 ENST00000373943.4
STX12
syntaxin 12
chr2_+_42721689 0.291 ENST00000405592.1
MTA3
metastasis associated 1 family, member 3
chr3_+_132036243 0.287 ENST00000475741.1
ENST00000351273.7
ACPP

acid phosphatase, prostate

chr11_-_8615720 0.281 ENST00000358872.3
ENST00000454443.2
STK33

serine/threonine kinase 33

chr10_+_123922941 0.281 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr4_-_186733363 0.280 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr6_+_116691001 0.280 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr12_+_14927270 0.279 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr6_-_27782548 0.278 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr9_-_32526299 0.277 ENST00000379882.1
ENST00000379883.2
DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

chr14_-_106586656 0.274 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr11_+_34642656 0.274 ENST00000257831.3
ENST00000450654.2
EHF

ets homologous factor

chr6_+_143999072 0.270 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2


phosphatase and actin regulator 2


chr11_-_27494309 0.268 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr2_-_219906220 0.267 ENST00000458526.1
ENST00000409865.3
ENST00000410037.1
ENST00000457968.1
ENST00000436631.1
ENST00000341552.5
ENST00000441968.1
ENST00000295729.2
CCDC108







coiled-coil domain containing 108








Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6 1.7 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.5 1.4 GO:1901253 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.5 5.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 1.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.4 1.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.3 6.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 2.1 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.6 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 0.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.7 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.5 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.4 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.4 GO:0008050 female courtship behavior(GO:0008050)
0.1 1.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 6.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 3.3 GO:0060074 synapse maturation(GO:0060074)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.3 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 1.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 7.6 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.3 GO:0010842 retina layer formation(GO:0010842)
0.1 1.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 1.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:1904956 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 1.7 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 0.4 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.4 GO:0006983 ER overload response(GO:0006983)
0.0 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0006811 ion transport(GO:0006811)
0.0 3.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 1.2 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 1.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 3.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0048278 vesicle docking(GO:0048278)
0.0 1.3 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.0 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 18.3 GO:0000786 nucleosome(GO:0000786)
0.2 1.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 6.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 2.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 3.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.8 3.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 1.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.4 1.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 2.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 3.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 0.9 GO:0016160 amylase activity(GO:0016160)
0.2 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 6.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 1.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 15.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 2.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 3.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 19.8 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 2.7 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 1.7 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.0 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 2.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway