Motif ID: POU1F1

Z-value: 0.516


Transcription factors associated with POU1F1:

Gene SymbolEntrez IDGene Name
POU1F1 ENSG00000064835.6 POU1F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v2_chr3_-_87325612_87325654-0.155.0e-01Click!


Activity profile for motif POU1F1.

activity profile for motif POU1F1


Sorted Z-values histogram for motif POU1F1

Sorted Z-values for motif POU1F1



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_13141097 1.272 ENST00000411542.1
AC011288.2
AC011288.2
chr16_-_30122717 1.241 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr5_+_147691979 0.785 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr1_+_115572415 0.638 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr17_-_5321549 0.567 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr10_+_94352956 0.526 ENST00000260731.3
KIF11
kinesin family member 11
chr8_-_91095099 0.518 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr18_-_59274139 0.477 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr9_+_125133315 0.440 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr4_-_159956333 0.390 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr1_-_205391178 0.390 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr1_+_192127578 0.384 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr1_-_197036364 0.378 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr19_-_43969796 0.378 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr18_+_29027696 0.369 ENST00000257189.4
DSG3
desmoglein 3
chr10_+_52152766 0.357 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr2_-_190044480 0.348 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr9_+_18474204 0.341 ENST00000276935.6
ADAMTSL1
ADAMTS-like 1
chr11_+_35201826 0.326 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr19_-_36001113 0.320 ENST00000434389.1
DMKN
dermokine
chr4_-_153601136 0.312 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr15_+_67418047 0.298 ENST00000540846.2
SMAD3
SMAD family member 3
chrX_-_11308598 0.288 ENST00000380717.3
ARHGAP6
Rho GTPase activating protein 6
chr9_-_21351377 0.281 ENST00000380210.1
IFNA6
interferon, alpha 6
chr6_-_134861089 0.277 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr1_-_67266939 0.269 ENST00000304526.2
INSL5
insulin-like 5
chr3_-_48130707 0.268 ENST00000360240.6
ENST00000383737.4
MAP4

microtubule-associated protein 4

chr13_+_32313658 0.267 ENST00000380314.1
ENST00000298386.2
RXFP2

relaxin/insulin-like family peptide receptor 2

chr19_-_58864848 0.257 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr12_+_131438443 0.254 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr1_+_8378140 0.243 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chrX_-_55057403 0.242 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2



aminolevulinate, delta-, synthase 2



chr11_-_5323226 0.241 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr9_+_12693336 0.238 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr20_+_3776371 0.235 ENST00000245960.5
CDC25B
cell division cycle 25B
chr14_-_80697396 0.225 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr1_+_87012753 0.225 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr12_+_82347498 0.221 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr17_-_64225508 0.221 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chrX_+_84258832 0.219 ENST00000373173.2
APOOL
apolipoprotein O-like
chr10_-_75226166 0.218 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr8_-_110986918 0.216 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr10_+_62538089 0.202 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1


cyclin-dependent kinase 1


chr9_+_125132803 0.200 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_58655461 0.198 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr18_+_21269556 0.192 ENST00000399516.3
LAMA3
laminin, alpha 3
chr12_+_12510352 0.188 ENST00000298571.6
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr18_+_21269404 0.188 ENST00000313654.9
LAMA3
laminin, alpha 3
chr15_+_69365265 0.187 ENST00000415504.1
LINC00277
long intergenic non-protein coding RNA 277
chr4_+_71296204 0.185 ENST00000413702.1
MUC7
mucin 7, secreted
chr7_+_129932974 0.182 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr11_-_117186946 0.179 ENST00000313005.6
ENST00000528053.1
BACE1

beta-site APP-cleaving enzyme 1

chr8_+_11961898 0.178 ENST00000400085.3
ZNF705D
zinc finger protein 705D
chr12_-_10978957 0.177 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr4_+_74347400 0.176 ENST00000226355.3
AFM
afamin
chrX_+_153533275 0.176 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
TKTL1


transketolase-like 1


chr4_+_96012614 0.174 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr12_-_11287243 0.174 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr7_-_87342564 0.173 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr19_+_9296279 0.173 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr12_-_52761262 0.172 ENST00000257901.3
KRT85
keratin 85
chr6_+_26087646 0.171 ENST00000309234.6
HFE
hemochromatosis
chr9_+_111624577 0.166 ENST00000333999.3
ACTL7A
actin-like 7A
chr11_-_107729887 0.162 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr3_+_130650738 0.160 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr19_-_56826157 0.159 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A





zinc finger and SCAN domain containing 5A





chr8_+_98900132 0.159 ENST00000520016.1
MATN2
matrilin 2
chr16_-_67217844 0.159 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L


KIAA0895-like


chrX_-_71458802 0.158 ENST00000373657.1
ENST00000334463.3
ERCC6L

excision repair cross-complementing rodent repair deficiency, complementation group 6-like

chr6_-_49712123 0.158 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr19_+_54466179 0.156 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr17_+_61086917 0.155 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr20_+_30102231 0.151 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13




histocompatibility (minor) 13




chr9_-_34729457 0.149 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr12_-_7596735 0.149 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1


CD163 molecule-like 1


chr12_-_7656357 0.148 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163


CD163 molecule


chr2_-_166930131 0.147 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chrX_+_154113317 0.146 ENST00000354461.2
H2AFB1
H2A histone family, member B1
chr1_-_53608289 0.145 ENST00000371491.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr6_+_47749718 0.143 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
OPN5


opsin 5


chr5_+_119867159 0.141 ENST00000505123.1
PRR16
proline rich 16
chr2_-_163008903 0.140 ENST00000418842.2
ENST00000375497.3
GCG

glucagon

chr10_+_53806501 0.139 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr6_+_26087509 0.138 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr12_-_86650045 0.137 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_-_111754948 0.137 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr15_+_58702742 0.136 ENST00000356113.6
ENST00000414170.3
LIPC

lipase, hepatic

chr8_+_36641842 0.134 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr10_-_99052382 0.134 ENST00000466484.1
ENST00000358531.4
ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ARHGAP19

ARHGAP19-SLIT1


Rho GTPase activating protein 19

ARHGAP19-SLIT1 readthrough (NMD candidate)


chr2_-_43266680 0.134 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2


AC016735.2


chr11_+_55650773 0.132 ENST00000449290.2
TRIM51
tripartite motif-containing 51
chr12_-_95510743 0.132 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr5_-_36301984 0.130 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr6_-_49604545 0.129 ENST00000371175.4
ENST00000229810.7
RHAG

Rh-associated glycoprotein

chrX_-_77225135 0.129 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr5_-_88119580 0.128 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr18_+_616672 0.127 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr14_+_31046959 0.123 ENST00000547532.1
ENST00000555429.1
G2E3

G2/M-phase specific E3 ubiquitin protein ligase

chrX_-_154689596 0.121 ENST00000369444.2
H2AFB3
H2A histone family, member B3
chr1_+_149754227 0.121 ENST00000444948.1
ENST00000369168.4
FCGR1A

Fc fragment of IgG, high affinity Ia, receptor (CD64)

chr6_-_49712147 0.119 ENST00000433368.2
ENST00000354620.4
CRISP3

cysteine-rich secretory protein 3

chr3_+_28390637 0.118 ENST00000420223.1
ENST00000383768.2
ZCWPW2

zinc finger, CW type with PWWP domain 2

chr12_+_25205666 0.118 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr15_-_22448819 0.118 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr19_+_16940198 0.117 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3B


SIN3 transcription regulator family member B


chr4_+_5526883 0.115 ENST00000195455.2
C4orf6
chromosome 4 open reading frame 6
chrX_-_32173579 0.111 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chrX_+_154610428 0.110 ENST00000354514.4
H2AFB2
H2A histone family, member B2
chr14_-_101295407 0.110 ENST00000596284.1
AL117190.2
AL117190.2
chr14_+_61654271 0.107 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr12_+_93096759 0.107 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr4_+_3344141 0.107 ENST00000306648.7
RGS12
regulator of G-protein signaling 12
chr7_-_14026063 0.106 ENST00000443608.1
ENST00000438956.1
ETV1

ets variant 1

chr22_-_32767017 0.105 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr7_-_14026123 0.102 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1


ets variant 1


chr12_-_118797475 0.100 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr2_+_152214098 0.098 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_81575281 0.097 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr4_+_86525299 0.097 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr1_-_183559693 0.097 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2


neutrophil cytosolic factor 2


chr5_+_115177178 0.097 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr11_-_89224488 0.096 ENST00000534731.1
ENST00000527626.1
NOX4

NADPH oxidase 4

chr12_-_112123524 0.096 ENST00000327551.6
BRAP
BRCA1 associated protein
chr7_+_130126165 0.094 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr2_-_17981462 0.094 ENST00000402989.1
ENST00000428868.1
SMC6

structural maintenance of chromosomes 6

chr4_+_74301880 0.094 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr7_+_130126012 0.093 ENST00000341441.5
MEST
mesoderm specific transcript
chr1_+_81771806 0.093 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr6_+_114178512 0.093 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr7_+_107224364 0.092 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr7_-_76829125 0.092 ENST00000248598.5
FGL2
fibrinogen-like 2
chr5_+_60933634 0.090 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr3_+_160939050 0.090 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3



NMD3 ribosome export adaptor



chr4_+_76481258 0.090 ENST00000311623.4
ENST00000435974.2
C4orf26

chromosome 4 open reading frame 26

chr1_-_183560011 0.090 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr9_-_85882145 0.089 ENST00000328788.1
FRMD3
FERM domain containing 3
chr8_-_57233103 0.089 ENST00000303749.3
ENST00000522671.1
SDR16C5

short chain dehydrogenase/reductase family 16C, member 5

chr20_+_55904815 0.089 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11



SPO11 meiotic protein covalently bound to DSB



chr11_+_55578854 0.089 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr4_-_185275104 0.088 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr12_+_69753448 0.088 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS4



YEATS domain containing 4



chr1_-_247921982 0.087 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr2_+_161993465 0.087 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr12_+_93096619 0.086 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr5_-_93077293 0.085 ENST00000510627.4
POU5F2
POU domain class 5, transcription factor 2
chr2_+_210517895 0.085 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr19_-_4535233 0.083 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr16_+_28565230 0.083 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr8_+_7801144 0.082 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr20_+_30697298 0.079 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr7_-_140482926 0.077 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr17_+_1944790 0.074 ENST00000575162.1
DPH1
diphthamide biosynthesis 1
chr7_-_86688990 0.074 ENST00000450689.2
KIAA1324L
KIAA1324-like
chr19_+_572543 0.073 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
BSG


basigin (Ok blood group)


chrX_-_15288154 0.073 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9


ankyrin repeat and SOCS box containing 9


chrX_+_43515467 0.072 ENST00000338702.3
ENST00000542639.1
MAOA

monoamine oxidase A

chr4_-_139051839 0.071 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616


long intergenic non-protein coding RNA 616


chr12_-_86650077 0.071 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr6_+_154360476 0.069 ENST00000428397.2
OPRM1
opioid receptor, mu 1
chr10_+_18549645 0.068 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr17_-_41050716 0.068 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
LINC00671



long intergenic non-protein coding RNA 671



chr10_+_97759848 0.067 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B


coiled-coil and C2 domain containing 2B


chr8_-_49833978 0.065 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr2_+_234826016 0.063 ENST00000324695.4
ENST00000433712.2
TRPM8

transient receptor potential cation channel, subfamily M, member 8

chr10_-_28623368 0.060 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_+_119957554 0.060 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2


chr3_-_160823040 0.059 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1






beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)






chr10_-_50396425 0.059 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr17_+_45728427 0.059 ENST00000540627.1
KPNB1
karyopherin (importin) beta 1
chr6_+_42584847 0.058 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr9_-_95056010 0.057 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr7_+_99425633 0.057 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43







cytochrome P450, family 3, subfamily A, polypeptide 43







chr6_+_140175987 0.056 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1

RP5-899B16.1

chr15_+_64680003 0.056 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr3_+_132843652 0.055 ENST00000508711.1
TMEM108
transmembrane protein 108
chr10_-_115904361 0.055 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118

chr6_+_29429217 0.055 ENST00000396792.2
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr4_+_190861993 0.054 ENST00000524583.1
ENST00000531991.2
FRG1

FSHD region gene 1

chr11_+_122709200 0.054 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr12_+_8309630 0.053 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr7_-_141957847 0.053 ENST00000552471.1
ENST00000547058.2
PRSS58

protease, serine, 58

chr9_-_99540328 0.053 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510


zinc finger protein 510


chr9_-_95055956 0.052 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS



isoleucyl-tRNA synthetase



chr2_+_223162866 0.052 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr3_-_160823158 0.052 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1


beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)


chrX_+_150565653 0.051 ENST00000330374.6
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr4_+_186990298 0.051 ENST00000296795.3
ENST00000513189.1
TLR3

toll-like receptor 3

chr16_+_48278178 0.051 ENST00000285737.4
ENST00000535754.1
LONP2

lon peptidase 2, peroxisomal

chr5_+_137225158 0.051 ENST00000290431.5
PKD2L2
polycystic kidney disease 2-like 2
chr6_-_136788001 0.050 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr9_-_21239978 0.050 ENST00000380222.2
IFNA14
interferon, alpha 14
chr18_-_13915530 0.050 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr2_-_45795145 0.049 ENST00000535761.1
SRBD1
S1 RNA binding domain 1
chr19_+_52873166 0.049 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
ZNF880




zinc finger protein 880




chr8_+_70850403 0.047 ENST00000602248.1
AC090574.1
Uncharacterized protein
chr3_+_98216448 0.046 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr4_-_122854612 0.046 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr8_-_49834299 0.044 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr17_+_66255310 0.044 ENST00000448504.2
ARSG
arylsulfatase G
chr12_+_26348429 0.044 ENST00000242729.2
SSPN
sarcospan

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.8 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.6 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.0 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0030849 Y chromosome(GO:0000806) autosome(GO:0030849)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME_OPSINS Genes involved in Opsins