Motif ID: PAX7_NOBOX

Z-value: 0.567

Transcription factors associated with PAX7_NOBOX:

Gene SymbolEntrez IDGene Name
NOBOX ENSG00000106410.10 NOBOX
PAX7 ENSG00000009709.7 PAX7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NOBOXhg19_v2_chr7_-_144107320_144107320-0.368.6e-02Click!
PAX7hg19_v2_chr1_+_18957500_18957623-0.154.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of PAX7_NOBOX

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_35938674 3.884 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr3_+_63638339 3.667 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr12_-_25348007 2.854 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr6_+_43612750 2.035 ENST00000372165.4
ENST00000372163.4
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr1_+_47533160 1.114 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr4_+_165675197 1.076 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr17_-_39203519 1.065 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr22_-_39190116 0.932 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4

Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4

chr13_+_77522632 0.846 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr18_+_44526786 0.834 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr3_-_47324242 0.822 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9



kinesin family member 9



chr4_+_165675269 0.790 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr11_-_33913708 0.789 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_+_226013047 0.774 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr11_+_101918153 0.771 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr11_-_95522907 0.742 ENST00000358780.5
ENST00000542135.1
FAM76B

family with sequence similarity 76, member B

chr6_+_47624172 0.732 ENST00000507065.1
ENST00000296862.1
GPR111

G protein-coupled receptor 111

chr4_-_138453606 0.699 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr4_-_100356551 0.651 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_-_3030875 0.558 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 2.0 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.9 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.6 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.6 GO:0061157 mRNA destabilization(GO:0061157)
0.2 0.5 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0006068 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.4 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.5 GO:0097196 Shu complex(GO:0097196)
0.1 0.5 GO:0032010 phagolysosome(GO:0032010)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.7 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_FANCONI_PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway