Motif ID: PAX4

Z-value: 0.645


Transcription factors associated with PAX4:

Gene SymbolEntrez IDGene Name
PAX4 ENSG00000106331.10 PAX4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255724_1272557800.135.5e-01Click!


Activity profile for motif PAX4.

activity profile for motif PAX4


Sorted Z-values histogram for motif PAX4

Sorted Z-values for motif PAX4



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_32407619 3.909 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr16_-_28621353 3.587 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_-_20622478 1.740 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr11_-_93276582 1.704 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr17_+_72270380 1.642 ENST00000582036.1
ENST00000307504.5
DNAI2

dynein, axonemal, intermediate chain 2

chr4_+_39184024 1.618 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19




WD repeat domain 19




chr4_+_165675269 1.613 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr4_-_84030996 1.564 ENST00000411416.2
PLAC8
placenta-specific 8
chr6_-_130031358 1.400 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr11_+_86085778 1.328 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81



coiled-coil domain containing 81



chr11_-_124622134 1.292 ENST00000326621.5
VSIG2
V-set and immunoglobulin domain containing 2
chr19_+_14544099 1.197 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1


protein kinase N1


chr16_-_28621312 1.190 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_62474803 1.184 ENST00000533982.1
ENST00000360796.5
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr11_-_124622083 1.152 ENST00000403470.1
VSIG2
V-set and immunoglobulin domain containing 2
chr10_+_114135004 0.974 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_13134772 0.936 ENST00000587760.1
ENST00000585575.1
NFIX

nuclear factor I/X (CCAAT-binding transcription factor)

chr15_-_40401062 0.904 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF



Bcl2 modifying factor



chr6_+_32605195 0.900 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr18_-_53255766 0.893 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr16_-_84273304 0.893 ENST00000308251.4
ENST00000568181.1
KCNG4

potassium voltage-gated channel, subfamily G, member 4

chr4_+_3465027 0.886 ENST00000389653.2
ENST00000507039.1
ENST00000340083.5
DOK7


docking protein 7


chr17_+_72322346 0.878 ENST00000551294.1
ENST00000389916.4
KIF19

kinesin family member 19

chr16_-_28621298 0.873 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr18_-_53089723 0.857 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr2_-_170550877 0.852 ENST00000447353.1
CCDC173
coiled-coil domain containing 173
chr11_-_114466477 0.848 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr5_-_20575959 0.843 ENST00000507958.1
CDH18
cadherin 18, type 2
chr2_-_217560248 0.840 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr9_+_92219919 0.833 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr3_-_127872625 0.819 ENST00000464873.1
RUVBL1
RuvB-like AAA ATPase 1
chr7_+_133812052 0.801 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr16_-_28608364 0.794 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr19_+_11708259 0.753 ENST00000587939.1
ENST00000588174.1
ZNF627

zinc finger protein 627

chr11_+_1874200 0.730 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr6_+_32605134 0.709 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1


major histocompatibility complex, class II, DQ alpha 1


chr19_+_11708229 0.705 ENST00000361113.5
ZNF627
zinc finger protein 627
chr4_+_30723003 0.692 ENST00000543491.1
PCDH7
protocadherin 7
chr16_-_28608424 0.688 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr7_-_130080977 0.687 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr11_-_114466471 0.633 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr7_+_69064300 0.627 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr7_+_26191809 0.620 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr1_-_1677358 0.616 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
SLC35E2


solute carrier family 35, member E2


chr16_+_69958887 0.615 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr9_+_100000717 0.572 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180




coiled-coil domain containing 180




chr2_-_85839146 0.567 ENST00000306336.5
ENST00000409734.3
C2orf68

chromosome 2 open reading frame 68

chr6_-_31697977 0.566 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr5_-_13944652 0.543 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr20_-_34117447 0.525 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173



chromosome 20 open reading frame 173



chr11_+_134144139 0.521 ENST00000389887.5
GLB1L3
galactosidase, beta 1-like 3
chr5_-_133304473 0.495 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr9_+_27109392 0.483 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr19_-_37064145 0.472 ENST00000591340.1
ENST00000334116.7
ZNF529

zinc finger protein 529

chr17_+_33895090 0.464 ENST00000592381.1
RP11-1094M14.11
RP11-1094M14.11
chr18_+_72922710 0.462 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr2_-_191184571 0.420 ENST00000392332.3
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_72848092 0.420 ENST00000344575.3
FZD9
frizzled family receptor 9
chr1_+_210001309 0.383 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr8_-_144660771 0.380 ENST00000449291.2
NAPRT1
nicotinate phosphoribosyltransferase domain containing 1
chr4_+_140586922 0.371 ENST00000265498.1
ENST00000506797.1
MGST2

microsomal glutathione S-transferase 2

chr12_+_122181529 0.360 ENST00000541467.1
TMEM120B
transmembrane protein 120B
chr11_+_120107344 0.359 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr7_+_5919458 0.358 ENST00000416608.1
OCM
oncomodulin
chr21_-_21630994 0.358 ENST00000436373.1
AP001171.1
AP001171.1
chr19_-_49622348 0.340 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr2_+_170550944 0.334 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
PHOSPHO2



KLHL23

phosphatase, orphan 2



kelch-like family member 23

chr7_-_16872932 0.333 ENST00000419572.2
ENST00000412973.1
AGR2

anterior gradient 2

chr7_-_96654133 0.319 ENST00000486603.2
ENST00000222598.4
DLX5

distal-less homeobox 5

chr4_+_170541835 0.316 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr10_-_70092671 0.314 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD


phenazine biosynthesis-like protein domain containing


chr17_-_42295870 0.314 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF


upstream binding transcription factor, RNA polymerase I


chr12_-_121477039 0.310 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr19_-_52551814 0.308 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
ZNF432


zinc finger protein 432


chr5_-_93447333 0.308 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A


family with sequence similarity 172, member A


chr12_+_118573663 0.305 ENST00000261313.2
PEBP1
phosphatidylethanolamine binding protein 1
chr22_-_31688381 0.297 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr4_+_170541678 0.295 ENST00000360642.3
ENST00000512813.1
CLCN3

chloride channel, voltage-sensitive 3

chr12_-_118406028 0.295 ENST00000425217.1
KSR2
kinase suppressor of ras 2
chr19_+_49622646 0.294 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr17_+_47448102 0.289 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr1_-_1624083 0.287 ENST00000378662.1
ENST00000234800.6
SLC35E2B

solute carrier family 35, member E2B

chr2_+_12857043 0.286 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr12_-_45269430 0.282 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr4_-_492891 0.281 ENST00000338977.5
ENST00000511833.2
ZNF721

zinc finger protein 721

chr20_-_52210368 0.276 ENST00000371471.2
ZNF217
zinc finger protein 217
chr22_-_31688431 0.275 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr20_+_277737 0.275 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr9_-_136933615 0.274 ENST00000371834.2
BRD3
bromodomain containing 3
chr16_+_53088885 0.273 ENST00000566029.1
ENST00000447540.1
CHD9

chromodomain helicase DNA binding protein 9

chr19_+_49891475 0.269 ENST00000447857.3
CCDC155
coiled-coil domain containing 155
chr12_-_121476959 0.269 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr7_+_66386204 0.268 ENST00000341567.4
ENST00000607045.1
TMEM248

transmembrane protein 248

chr2_+_47630255 0.264 ENST00000406134.1
MSH2
mutS homolog 2
chr12_+_110906169 0.260 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr2_+_47630108 0.258 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chrX_-_102942961 0.258 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2


mortality factor 4 like 2


chr4_+_170541660 0.253 ENST00000513761.1
ENST00000347613.4
CLCN3

chloride channel, voltage-sensitive 3

chr2_-_208489707 0.249 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A


methyltransferase like 21A


chr7_-_137686791 0.238 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2


cAMP responsive element binding protein 3-like 2


chr19_+_24216213 0.237 ENST00000342944.6
ENST00000594934.1
ENST00000597683.1
ZNF254
CTD-2017D11.1

zinc finger protein 254
CTD-2017D11.1

chr2_+_217735493 0.231 ENST00000456163.1
AC007557.1
HCG1816075; Uncharacterized protein
chr7_-_130080818 0.229 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
CEP41


centrosomal protein 41kDa


chr17_+_7184986 0.225 ENST00000317370.8
ENST00000571308.1
SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

chr11_+_46740730 0.223 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2


coagulation factor II (thrombin)


chr20_-_44993012 0.222 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2




solute carrier family 35 (GDP-fucose transporter), member C2




chr12_+_31812121 0.220 ENST00000395763.3
METTL20
methyltransferase like 20
chrM_+_5824 0.217 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr12_-_123717643 0.214 ENST00000541437.1
ENST00000606320.1
MPHOSPH9

M-phase phosphoprotein 9

chr1_-_151319283 0.214 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr12_-_120763739 0.204 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr12_+_50017184 0.200 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr8_+_41348072 0.198 ENST00000405786.2
GOLGA7
golgin A7
chr1_-_182360918 0.196 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr9_+_134103496 0.195 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214


nucleoporin 214kDa


chr8_+_145215928 0.194 ENST00000528919.1
MROH1
maestro heat-like repeat family member 1
chr8_-_145653885 0.194 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
VPS28




vacuolar protein sorting 28 homolog (S. cerevisiae)




chr9_+_70971815 0.194 ENST00000396392.1
ENST00000396396.1
PGM5

phosphoglucomutase 5

chr10_+_102295616 0.192 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr17_+_1674982 0.189 ENST00000572048.1
ENST00000573763.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr2_-_20251744 0.188 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chrX_-_131547596 0.188 ENST00000538204.1
ENST00000370849.3
MBNL3

muscleblind-like splicing regulator 3

chr21_+_43933946 0.187 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr7_-_37488834 0.186 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chrX_-_47004878 0.186 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr6_+_34857019 0.186 ENST00000360359.3
ENST00000535627.1
ANKS1A

ankyrin repeat and sterile alpha motif domain containing 1A

chr3_+_39424828 0.184 ENST00000273158.4
ENST00000431510.1
SLC25A38

solute carrier family 25, member 38

chr1_+_41157361 0.184 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC




nuclear transcription factor Y, gamma




chr6_+_55039050 0.183 ENST00000370862.3
HCRTR2
hypocretin (orexin) receptor 2
chr10_-_70092635 0.178 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr1_+_22889953 0.178 ENST00000374644.4
ENST00000166244.3
ENST00000538803.1
EPHA8


EPH receptor A8


chr7_+_69064566 0.175 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr17_+_16284399 0.174 ENST00000535788.1
UBB
ubiquitin B
chrX_+_110187513 0.172 ENST00000446737.1
ENST00000425146.1
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr8_+_41347915 0.172 ENST00000518270.1
ENST00000520817.1
GOLGA7

golgin A7

chrX_-_102943022 0.165 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr6_-_10694766 0.164 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52


chromosome 6 open reading frame 52


chr8_+_17434689 0.161 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr2_-_85555385 0.160 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr11_+_20385231 0.160 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2



HIV-1 Tat interactive protein 2, 30kDa



chr5_-_58882219 0.158 ENST00000505453.1
ENST00000360047.5
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_168756151 0.152 ENST00000420691.1
LINC00626
long intergenic non-protein coding RNA 626
chr1_-_38156153 0.152 ENST00000464085.1
ENST00000486637.1
ENST00000358011.4
ENST00000461359.1
C1orf109



chromosome 1 open reading frame 109



chr1_-_182360498 0.152 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chrX_-_131547625 0.151 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr7_+_140396465 0.150 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2





NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa





chr3_+_51895621 0.148 ENST00000333127.3
IQCF2
IQ motif containing F2
chr8_-_7673238 0.147 ENST00000335021.2
DEFB107A
defensin, beta 107A
chr8_-_21771182 0.135 ENST00000523932.1
ENST00000544659.1
DOK2

docking protein 2, 56kDa

chr3_-_9921934 0.133 ENST00000423850.1
CIDEC
cell death-inducing DFFA-like effector c
chr3_-_79816965 0.132 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_+_492985 0.129 ENST00000296306.7
ENST00000536264.1
ENST00000310340.5
ENST00000453061.2
ENST00000504346.1
ENST00000503111.1
ENST00000383028.4
ENST00000509768.1
PIGG







phosphatidylinositol glycan anchor biosynthesis, class G







chr2_+_190526111 0.129 ENST00000607062.1
ENST00000260952.4
ENST00000425590.1
ENST00000607535.1
ENST00000420250.1
ENST00000606910.1
ENST00000607690.1
ENST00000607829.1
ASNSD1







asparagine synthetase domain containing 1







chr18_-_3874271 0.128 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr8_-_38853990 0.123 ENST00000456845.2
ENST00000397070.2
ENST00000517872.1
ENST00000412303.1
ENST00000456397.2
TM2D2




TM2 domain containing 2




chr18_-_60986962 0.121 ENST00000333681.4
BCL2
B-cell CLL/lymphoma 2
chr8_-_116681221 0.117 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chrX_-_48827976 0.114 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr11_+_22689648 0.113 ENST00000278187.3
GAS2
growth arrest-specific 2
chr8_-_21771214 0.113 ENST00000276420.4
DOK2
docking protein 2, 56kDa
chr19_+_9361606 0.111 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr13_+_76334498 0.109 ENST00000534657.1
LMO7
LIM domain 7
chr4_+_174292058 0.109 ENST00000296504.3
SAP30
Sin3A-associated protein, 30kDa
chr6_+_134274322 0.107 ENST00000367871.1
ENST00000237264.4
TBPL1

TBP-like 1

chr1_+_145524891 0.106 ENST00000369304.3
ITGA10
integrin, alpha 10
chr19_-_53193731 0.104 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
ZNF83


zinc finger protein 83


chr18_+_3448455 0.100 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr11_-_35440579 0.097 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_+_186383741 0.097 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr11_+_20385327 0.093 ENST00000451739.2
ENST00000532505.1
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr14_+_104394770 0.093 ENST00000409874.4
ENST00000339063.5
TDRD9

tudor domain containing 9

chr12_-_110888103 0.088 ENST00000426440.1
ENST00000228825.7
ARPC3

actin related protein 2/3 complex, subunit 3, 21kDa

chr5_-_32444828 0.088 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr9_+_19049372 0.086 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr6_-_32095968 0.084 ENST00000375203.3
ENST00000375201.4
ATF6B

activating transcription factor 6 beta

chr19_-_51961702 0.081 ENST00000430817.1
ENST00000321424.3
ENST00000340550.5
SIGLEC8


sialic acid binding Ig-like lectin 8


chr1_-_208084729 0.078 ENST00000310833.7
ENST00000356522.4
CD34

CD34 molecule

chr17_+_16284104 0.078 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB


ubiquitin B


chr1_+_41157421 0.076 ENST00000372654.1
NFYC
nuclear transcription factor Y, gamma
chr1_-_25291475 0.074 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chrX_+_66764375 0.073 ENST00000374690.3
AR
androgen receptor
chr11_-_59578202 0.073 ENST00000300151.4
MRPL16
mitochondrial ribosomal protein L16
chr6_+_10694900 0.071 ENST00000379568.3
PAK1IP1
PAK1 interacting protein 1
chr19_-_6333614 0.069 ENST00000301452.4
ACER1
alkaline ceramidase 1
chrX_-_31285042 0.067 ENST00000378680.2
ENST00000378723.3
DMD

dystrophin

chr6_+_31554456 0.066 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr22_+_23229960 0.065 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5


immunoglobulin lambda-like polypeptide 5


chr2_-_10830093 0.064 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
NOL10



nucleolar protein 10



chr21_+_26934165 0.061 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr2_+_102972363 0.060 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr7_-_139763521 0.059 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr8_+_12809093 0.057 ENST00000528753.2
KIAA1456
KIAA1456
chr4_-_76439596 0.056 ENST00000451788.1
ENST00000512706.1
RCHY1

ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

chr6_+_31554636 0.054 ENST00000433492.1
LST1
leukocyte specific transcript 1
chr13_-_28194541 0.054 ENST00000316334.3
LNX2
ligand of numb-protein X 2
chr19_-_36391434 0.050 ENST00000396901.1
ENST00000585925.1
NFKBID

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

chr7_-_96339132 0.049 ENST00000413065.1
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr8_+_12808834 0.048 ENST00000400069.3
KIAA1456
KIAA1456
chr7_-_140098257 0.047 ENST00000340308.3
ENST00000447932.2
ENST00000429996.2
ENST00000469193.1
ENST00000326232.9
SLC37A3




solute carrier family 37, member 3




chr1_-_20503917 0.045 ENST00000429261.2
PLA2G2C
phospholipase A2, group IIC

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 1.6 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 7.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 0.8 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.2 1.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 1.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.5 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 2.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.2 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 1.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185) positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.2 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.0 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.6 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.5 GO:0097503 sialylation(GO:0097503)
0.0 2.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.0 0.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.2 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.0 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.0 GO:0018195 peptidyl-arginine modification(GO:0018195)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 2.2 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.5 GO:0032302 MutSbeta complex(GO:0032302)
0.2 1.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:0002177 manchette(GO:0002177)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 0.3 GO:1990742 microvesicle(GO:1990742)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.4 5.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.5 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0033677 DNA/RNA helicase activity(GO:0033677)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 1.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID_MYC_PATHWAY C-MYC pathway
0.0 1.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.0 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters