Motif ID: OTX1

Z-value: 0.714


Transcription factors associated with OTX1:

Gene SymbolEntrez IDGene Name
OTX1 ENSG00000115507.5 OTX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_632779380.573.3e-03Click!


Activity profile for motif OTX1.

activity profile for motif OTX1


Sorted Z-values histogram for motif OTX1

Sorted Z-values for motif OTX1



Network of associatons between targets according to the STRING database.



First level regulatory network of OTX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_65769392 3.511 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr19_-_55677999 3.118 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr19_-_55677920 3.022 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr17_-_4689649 2.479 ENST00000441199.2
ENST00000416307.2
VMO1

vitelline membrane outer layer 1 homolog (chicken)

chr12_-_71533055 2.340 ENST00000552128.1
TSPAN8
tetraspanin 8
chr2_-_160654745 1.949 ENST00000259053.4
ENST00000429078.2
CD302

CD302 molecule

chr12_+_20963647 1.753 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_-_146696901 1.729 ENST00000369272.3
ENST00000441068.2
FMO5

flavin containing monooxygenase 5

chr12_+_20963632 1.713 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr2_+_102721023 1.521 ENST00000409589.1
ENST00000409329.1
IL1R1

interleukin 1 receptor, type I

chr9_-_35563896 1.456 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr3_+_58223228 1.382 ENST00000478253.1
ENST00000295962.4
ABHD6

abhydrolase domain containing 6

chr17_-_34329084 1.270 ENST00000536149.1
ENST00000354059.4
CCL14
CCL15
chemokine (C-C motif) ligand 14
chemokine (C-C motif) ligand 15
chr10_+_114133773 1.232 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_+_111393659 1.227 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_-_104211294 1.159 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr17_+_41158742 1.141 ENST00000415816.2
ENST00000438323.2
IFI35

interferon-induced protein 35

chr3_+_42544084 1.108 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1



vasoactive intestinal peptide receptor 1



chr8_-_133637624 1.105 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr20_+_48884002 1.077 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3

RP11-290F20.3

chr2_+_170335924 1.035 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5

RP11-724O16.1
Bardet-Biedl syndrome 5

Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr1_-_92351769 0.989 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr6_-_9939552 0.879 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr14_-_89878369 0.871 ENST00000553840.1
ENST00000556916.1
FOXN3

forkhead box N3

chr10_-_50122277 0.836 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chr3_-_193272874 0.818 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr7_-_120498357 0.799 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chr3_-_193272741 0.769 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr15_-_55657428 0.739 ENST00000568543.1
CCPG1
cell cycle progression 1
chr22_+_39052632 0.713 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr1_+_63989004 0.709 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr1_+_170501270 0.690 ENST00000367763.3
ENST00000367762.1
GORAB

golgin, RAB6-interacting

chr12_-_107380910 0.688 ENST00000392830.2
ENST00000240050.4
MTERFD3

MTERF domain containing 3

chr14_-_24911448 0.644 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1





short chain dehydrogenase/reductase family 39U, member 1





chr19_-_47616992 0.638 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr1_+_196621002 0.627 ENST00000367429.4
ENST00000439155.2
CFH

complement factor H

chr1_-_154928562 0.620 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr12_-_107380846 0.616 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3


MTERF domain containing 3


chr15_-_43876702 0.610 ENST00000348806.6
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr14_-_102706934 0.605 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK


MOK protein kinase


chr2_+_109403193 0.605 ENST00000412964.2
ENST00000295124.4
CCDC138

coiled-coil domain containing 138

chr1_+_174844645 0.605 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr15_-_43877062 0.600 ENST00000381885.1
ENST00000396923.3
PPIP5K1

diphosphoinositol pentakisphosphate kinase 1

chr21_+_44073916 0.592 ENST00000349112.3
ENST00000398224.3
PDE9A

phosphodiesterase 9A

chr1_+_40840320 0.590 ENST00000372708.1
SMAP2
small ArfGAP2
chr3_-_27410847 0.586 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10


NIMA-related kinase 10


chr4_+_189060573 0.583 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr3_+_195447738 0.578 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chr12_+_108523133 0.565 ENST00000547525.1
WSCD2
WSC domain containing 2
chr8_-_10512569 0.538 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr1_-_247335269 0.537 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124



zinc finger protein 124



chr19_+_35940486 0.521 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr15_-_61521495 0.492 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr2_+_201936458 0.478 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr17_-_56769382 0.476 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14


testis expressed 14


chr5_-_111091948 0.474 ENST00000447165.2
NREP
neuronal regeneration related protein
chr16_-_8962200 0.439 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1


calcium regulated heat stable protein 1, 24kDa


chr3_+_138340049 0.416 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr3_-_58572760 0.407 ENST00000447756.2
FAM107A
family with sequence similarity 107, member A
chr16_+_14802801 0.406 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr20_-_3140490 0.405 ENST00000449731.1
ENST00000380266.3
UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr1_+_172502336 0.402 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chrX_-_100307043 0.394 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
TRMT2B


tRNA methyltransferase 2 homolog B (S. cerevisiae)


chr2_+_204103663 0.386 ENST00000356079.4
ENST00000429815.2
CYP20A1

cytochrome P450, family 20, subfamily A, polypeptide 1

chr8_-_33370607 0.385 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr12_+_124997766 0.378 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr11_-_67275542 0.378 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr3_+_142315225 0.372 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chr2_-_234475380 0.369 ENST00000443711.2
ENST00000251722.6
USP40

ubiquitin specific peptidase 40

chr11_-_62420757 0.366 ENST00000330574.2
INTS5
integrator complex subunit 5
chr19_+_21265028 0.354 ENST00000291770.7
ZNF714
zinc finger protein 714
chr22_+_30163340 0.354 ENST00000330029.6
ENST00000401406.3
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr19_+_10531150 0.354 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr8_-_79717750 0.343 ENST00000263851.4
ENST00000379113.2
IL7

interleukin 7

chr12_-_54071181 0.340 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr10_-_28571015 0.328 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr16_-_58163299 0.327 ENST00000262498.3
C16orf80
chromosome 16 open reading frame 80
chr11_-_130786333 0.322 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19



sorting nexin 19



chr8_-_145652336 0.316 ENST00000529182.1
ENST00000526054.1
VPS28

vacuolar protein sorting 28 homolog (S. cerevisiae)

chr3_+_138340067 0.304 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chrM_+_12331 0.297 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr4_+_159727272 0.294 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr14_-_102552659 0.290 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr14_+_50234309 0.288 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr1_+_229440129 0.283 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr3_-_141747950 0.281 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_16539094 0.275 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr9_+_116172958 0.269 ENST00000374165.1
C9orf43
chromosome 9 open reading frame 43
chr11_+_113258495 0.265 ENST00000303941.3
ANKK1
ankyrin repeat and kinase domain containing 1
chr3_+_192958914 0.253 ENST00000264735.2
ENST00000602513.1
HRASLS

HRAS-like suppressor

chr13_-_31736478 0.251 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr1_+_18434240 0.246 ENST00000251296.1
IGSF21
immunoglobin superfamily, member 21
chr12_+_7864021 0.244 ENST00000345088.2
DPPA3
developmental pluripotency associated 3
chr4_-_54424366 0.243 ENST00000306888.2
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr7_-_91509986 0.240 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF




mitochondrial transcription termination factor




chr8_+_109455845 0.232 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr8_+_132916318 0.230 ENST00000254624.5
ENST00000522709.1
EFR3A

EFR3 homolog A (S. cerevisiae)

chr21_-_43816052 0.226 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr22_-_30162924 0.220 ENST00000344318.3
ENST00000397781.3
ZMAT5

zinc finger, matrin-type 5

chr5_+_177631497 0.214 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr16_-_29874462 0.208 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT


CDP-diacylglycerol--inositol 3-phosphatidyltransferase


chr15_+_75550940 0.208 ENST00000300576.5
GOLGA6C
golgin A6 family, member C
chr12_-_117537240 0.202 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC


tescalcin


chr6_-_137539651 0.200 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr14_-_27066960 0.191 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr19_-_41903161 0.190 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5



exosome component 5



chr19_+_17448348 0.190 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTPBP3


GTP binding protein 3 (mitochondrial)


chr1_-_151300160 0.188 ENST00000368874.4
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr5_+_101569696 0.187 ENST00000597120.1
AC008948.1
AC008948.1
chr6_-_32731243 0.185 ENST00000427449.1
ENST00000411527.1
HLA-DQB2

major histocompatibility complex, class II, DQ beta 2

chr5_-_59783882 0.184 ENST00000505507.2
ENST00000502484.2
PDE4D

phosphodiesterase 4D, cAMP-specific

chr16_-_21436459 0.182 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3


nuclear pore complex interacting protein family, member B3


chr3_-_12587055 0.182 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr5_+_140079919 0.182 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr6_+_132873832 0.179 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr10_+_52724028 0.179 ENST00000561565.1
RP11-96B5.4
RP11-96B5.4
chr12_+_49740700 0.175 ENST00000549441.2
ENST00000395069.3
DNAJC22

DnaJ (Hsp40) homolog, subfamily C, member 22

chr1_+_45805342 0.164 ENST00000372090.5
TOE1
target of EGR1, member 1 (nuclear)
chr3_-_156878540 0.160 ENST00000461804.1
CCNL1
cyclin L1
chr12_-_14956396 0.158 ENST00000535328.1
ENST00000261167.2
WBP11

WW domain binding protein 11

chr9_-_113100088 0.157 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8



thioredoxin domain containing 8 (spermatozoa)



chrX_+_1734051 0.157 ENST00000381229.4
ENST00000381233.3
ASMT

acetylserotonin O-methyltransferase

chrX_+_1733876 0.155 ENST00000381241.3
ASMT
acetylserotonin O-methyltransferase
chr3_-_69129501 0.154 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3



ubiquitin-like modifier activating enzyme 3



chr17_-_8770956 0.154 ENST00000311434.9
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr7_+_99195878 0.152 ENST00000453227.1
ENST00000429679.1
GS1-259H13.2

GS1-259H13.2

chr5_+_134303591 0.151 ENST00000282611.6
CATSPER3
cation channel, sperm associated 3
chr10_-_35104185 0.141 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3










par-3 family cell polarity regulator










chr10_+_60028818 0.140 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr2_+_201936707 0.134 ENST00000433898.1
ENST00000454214.1
NDUFB3

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

chr1_+_81771806 0.129 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr11_-_111957451 0.127 ENST00000504148.2
ENST00000541231.1
TIMM8B

translocase of inner mitochondrial membrane 8 homolog B (yeast)

chr7_-_100895414 0.125 ENST00000435848.1
ENST00000474120.1
FIS1

fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)

chr2_-_161350305 0.124 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_+_24755416 0.119 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr1_+_40723779 0.118 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr7_+_99195677 0.117 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chr20_-_33539655 0.115 ENST00000451957.2
GSS
glutathione synthetase
chr1_+_117910047 0.113 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_+_150293973 0.112 ENST00000414970.2
ENST00000543398.1
PRPF3

pre-mRNA processing factor 3

chr6_+_38690622 0.111 ENST00000327475.6
DNAH8
dynein, axonemal, heavy chain 8
chr20_+_3052264 0.109 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr1_+_150293921 0.105 ENST00000324862.6
PRPF3
pre-mRNA processing factor 3
chr11_+_55944094 0.097 ENST00000312298.1
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chr9_-_100935043 0.096 ENST00000343933.5
CORO2A
coronin, actin binding protein, 2A
chr16_-_66583701 0.095 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2


thymidine kinase 2, mitochondrial


chr15_+_42787452 0.095 ENST00000249647.3
SNAP23
synaptosomal-associated protein, 23kDa
chrX_-_43832711 0.092 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr16_-_21868978 0.091 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4



nuclear pore complex interacting protein family, member B4



chr11_+_130029457 0.091 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr2_+_122513109 0.089 ENST00000389682.3
ENST00000536142.1
TSN

translin

chr22_-_36903101 0.088 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr6_-_133055815 0.088 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3






vanin 3






chr8_-_56986768 0.088 ENST00000523936.1
RPS20
ribosomal protein S20
chr4_+_100737954 0.085 ENST00000296414.7
ENST00000512369.1
DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides

chr17_-_39324424 0.082 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr8_+_101162812 0.081 ENST00000353107.3
ENST00000522439.1
POLR2K

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

chr7_+_55980331 0.079 ENST00000429591.2
ZNF713
zinc finger protein 713
chr5_-_154230130 0.079 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2



fatty acid hydroxylase domain containing 2



chr13_+_23755099 0.077 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr5_-_147286065 0.077 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr6_+_140175987 0.073 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1

RP5-899B16.1

chr1_+_24882560 0.073 ENST00000374392.2
NCMAP
noncompact myelin associated protein
chr2_-_112642267 0.072 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1
chr5_-_54603368 0.072 ENST00000508346.1
ENST00000251636.5
DHX29

DEAH (Asp-Glu-Ala-His) box polypeptide 29

chr2_-_201936302 0.071 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B



family with sequence similarity 126, member B



chrX_+_149861836 0.069 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1





myotubularin related protein 1





chr6_-_41039567 0.067 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr3_+_136649311 0.064 ENST00000469404.1
ENST00000467911.1
NCK1

NCK adaptor protein 1

chr1_-_205719295 0.064 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr17_-_26876350 0.063 ENST00000470125.1
UNC119
unc-119 homolog (C. elegans)
chr2_-_96192450 0.056 ENST00000609975.1
RP11-440D17.3
RP11-440D17.3
chr16_-_29415350 0.055 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr2_+_1418154 0.052 ENST00000423320.1
ENST00000382198.1
TPO

thyroid peroxidase

chr1_+_241695424 0.051 ENST00000366558.3
ENST00000366559.4
KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

chr16_-_69373396 0.049 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8


component of oligomeric golgi complex 8


chr5_+_135496675 0.043 ENST00000507637.1
SMAD5
SMAD family member 5
chr11_-_40315640 0.040 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr2_-_211090162 0.032 ENST00000233710.3
ACADL
acyl-CoA dehydrogenase, long chain
chrX_+_53123314 0.032 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5




long intergenic non-protein coding RNA 1155




chr3_-_51909600 0.024 ENST00000446461.1
IQCF5
IQ motif containing F5
chr2_-_111230393 0.021 ENST00000413601.2
ENST00000447537.2
LIMS3L
LIMS3L
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
chr2_+_234580525 0.017 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_234580499 0.015 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr4_+_83956237 0.012 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr16_-_69448 0.007 ENST00000326592.9
WASH4P
WAS protein family homolog 4 pseudogene
chr2_+_16080659 0.006 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr14_+_21458127 0.005 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17





methyltransferase like 17





chr3_-_69062764 0.005 ENST00000295571.5
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr18_+_8717369 0.004 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2


SOGA family member 2


chr21_+_18811205 0.004 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr9_-_116172946 0.003 ENST00000374171.4
POLE3
polymerase (DNA directed), epsilon 3, accessory subunit
chr1_-_160832642 0.003 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr5_+_59783941 0.001 ENST00000506884.1
ENST00000504876.2
PART1

prostate androgen-regulated transcript 1 (non-protein coding)

chr12_+_57881740 0.001 ENST00000262027.5
ENST00000315473.5
MARS

methionyl-tRNA synthetase

chr1_-_9811600 0.000 ENST00000435891.1
CLSTN1
calsyntenin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 8.3 GO:0044458 motile cilium assembly(GO:0044458)
0.2 1.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.3 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 3.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:2000653 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.5 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.7 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 1.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 2.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 1.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.6 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.4 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511) modification-dependent protein catabolic process(GO:0019941) modification-dependent macromolecule catabolic process(GO:0043632)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:1902911 protein kinase complex(GO:1902911)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.5 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 1.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 1.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 1.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 3.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.0 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 1.3 ST_ADRENERGIC Adrenergic Pathway
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 1.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.1 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma