Motif ID: NR4A2

Z-value: 0.497


Transcription factors associated with NR4A2:

Gene SymbolEntrez IDGene Name
NR4A2 ENSG00000153234.9 NR4A2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR4A2hg19_v2_chr2_-_157198860_1571989780.735.5e-05Click!


Activity profile for motif NR4A2.

activity profile for motif NR4A2


Sorted Z-values histogram for motif NR4A2

Sorted Z-values for motif NR4A2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792295 2.127 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr16_-_67427389 2.029 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr2_+_120189422 1.612 ENST00000306406.4
TMEM37
transmembrane protein 37
chr20_+_31755934 1.134 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr1_-_104238912 0.981 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr1_-_104239076 0.964 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr19_+_35629702 0.895 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr4_+_41614909 0.813 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr6_+_149068464 0.679 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr4_+_15471489 0.627 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A








coiled-coil and C2 domain containing 2A








chr2_-_27712583 0.597 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172


intraflagellar transport 172 homolog (Chlamydomonas)


chr22_+_32149927 0.585 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5







DEP domain containing 5







chr11_+_66624527 0.581 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_-_226129083 0.528 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr22_-_37880543 0.526 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr10_+_81107271 0.521 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr1_-_226129189 0.518 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr22_-_27620603 0.507 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1

RP5-1172A22.1

chr1_+_196621156 0.464 ENST00000359637.2
CFH
complement factor H
chr12_-_81992111 0.454 ENST00000443686.3
ENST00000407050.4
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr20_+_58179582 0.449 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr4_+_41614720 0.406 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr18_-_12377283 0.382 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr14_-_61190754 0.378 ENST00000216513.4
SIX4
SIX homeobox 4
chr22_+_31518938 0.376 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr1_+_9648921 0.366 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201


transmembrane protein 201


chr10_+_81107216 0.350 ENST00000394579.3
ENST00000225174.3
PPIF

peptidylprolyl isomerase F

chr14_+_21498666 0.339 ENST00000481535.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr5_+_149569520 0.330 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr16_-_28937027 0.327 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr13_+_97928395 0.327 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr22_-_24110063 0.324 ENST00000520222.1
ENST00000401675.3
CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

chr9_+_115983808 0.322 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr14_-_21492251 0.321 ENST00000554398.1
NDRG2
NDRG family member 2
chr7_-_72936608 0.320 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr14_-_21492113 0.311 ENST00000554094.1
NDRG2
NDRG family member 2
chrX_+_13587712 0.302 ENST00000361306.1
ENST00000380602.3
EGFL6

EGF-like-domain, multiple 6

chr2_+_219135115 0.281 ENST00000248451.3
ENST00000273077.4
PNKD

paroxysmal nonkinesigenic dyskinesia

chr1_+_196621002 0.278 ENST00000367429.4
ENST00000439155.2
CFH

complement factor H

chr5_-_169626104 0.275 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1

CTB-27N1.1

chr6_+_107077435 0.266 ENST00000369046.4
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr2_+_191334212 0.262 ENST00000444317.1
ENST00000535751.1
MFSD6

major facilitator superfamily domain containing 6

chr16_-_28936493 0.261 ENST00000544477.1
ENST00000357573.6
RABEP2

rabaptin, RAB GTPase binding effector protein 2

chr1_+_16062820 0.258 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr10_-_50970382 0.255 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr9_+_95997205 0.252 ENST00000411624.1
WNK2
WNK lysine deficient protein kinase 2
chr16_-_4466565 0.242 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7


CORO7-PAM16 readthrough
coronin 7


chr10_-_50970322 0.241 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr2_-_220110111 0.236 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L



galactosidase, beta 1-like



chr3_+_52813932 0.234 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr14_-_24911868 0.228 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr16_+_691792 0.228 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr8_+_21911054 0.228 ENST00000519850.1
ENST00000381470.3
DMTN

dematin actin binding protein

chr2_-_207024233 0.225 ENST00000423725.1
ENST00000233190.6
NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

chr14_+_21498360 0.221 ENST00000321760.6
ENST00000460647.2
ENST00000530140.2
ENST00000472458.1
TPPP2



tubulin polymerization-promoting protein family member 2



chr7_+_129007964 0.218 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2


adenosylhomocysteinase-like 2


chr19_+_1248547 0.212 ENST00000586757.1
ENST00000300952.2
MIDN

midnolin

chr16_-_30457048 0.201 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr1_-_20141763 0.200 ENST00000375121.2
RNF186
ring finger protein 186
chr2_-_25194963 0.199 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr22_+_30163340 0.193 ENST00000330029.6
ENST00000401406.3
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr7_-_150777874 0.193 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr1_-_20126365 0.183 ENST00000294543.6
ENST00000375122.2
TMCO4

transmembrane and coiled-coil domains 4

chr1_+_169075554 0.179 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_157108130 0.176 ENST00000368192.4
ETV3
ets variant 3
chr8_-_70745575 0.175 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr17_-_2614927 0.174 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr14_-_55369525 0.173 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1



GTP cyclohydrolase 1



chr5_-_137911049 0.172 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr1_+_212738676 0.171 ENST00000366981.4
ENST00000366987.2
ATF3

activating transcription factor 3

chr15_+_43885252 0.170 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B



creatine kinase, mitochondrial 1B



chr11_-_64511789 0.170 ENST00000419843.1
ENST00000394430.1
RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr17_-_1553346 0.165 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr3_-_179322436 0.165 ENST00000392659.2
ENST00000476781.1
MRPL47

mitochondrial ribosomal protein L47

chr20_+_37590942 0.163 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr7_-_150777949 0.160 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr7_-_27169801 0.160 ENST00000511914.1
HOXA4
homeobox A4
chr22_+_51176624 0.159 ENST00000216139.5
ENST00000529621.1
ACR

acrosin

chr12_-_108954933 0.159 ENST00000431469.2
ENST00000546815.1
SART3

squamous cell carcinoma antigen recognized by T cells 3

chr7_-_150777920 0.159 ENST00000353841.2
ENST00000297532.6
FASTK

Fas-activated serine/threonine kinase

chr14_+_23791159 0.157 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr3_-_179322416 0.157 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr4_-_74088800 0.156 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr10_+_76586348 0.153 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr12_+_120875910 0.152 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr16_+_4674787 0.151 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr15_+_43985084 0.149 ENST00000434505.1
ENST00000411750.1
CKMT1A

creatine kinase, mitochondrial 1A

chr17_-_79167828 0.148 ENST00000570817.1
AZI1
5-azacytidine induced 1
chr12_-_46121554 0.146 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr16_-_69368774 0.146 ENST00000562949.1
RP11-343C2.12
Conserved oligomeric Golgi complex subunit 8
chr8_+_134125727 0.144 ENST00000521107.1
TG
thyroglobulin
chr1_+_206858328 0.143 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr2_-_176046391 0.141 ENST00000392541.3
ENST00000409194.1
ATP5G3

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)

chr7_-_91875358 0.138 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1



KRIT1, ankyrin repeat containing



chr7_+_73245193 0.136 ENST00000340958.2
CLDN4
claudin 4
chr22_-_43036607 0.136 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr4_-_71705082 0.136 ENST00000439371.1
ENST00000499044.2
GRSF1

G-rich RNA sequence binding factor 1

chr4_+_146560245 0.134 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr9_-_138853156 0.134 ENST00000371756.3
UBAC1
UBA domain containing 1
chr11_-_110583912 0.133 ENST00000533353.1
ENST00000527598.1
ARHGAP20

Rho GTPase activating protein 20

chr10_-_51623203 0.133 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
TIMM23



translocase of inner mitochondrial membrane 23 homolog (yeast)



chr3_-_46000064 0.132 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr22_+_50354104 0.128 ENST00000360612.4
PIM3
pim-3 oncogene
chr11_+_3876859 0.127 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr3_+_128968437 0.127 ENST00000314797.6
COPG1
coatomer protein complex, subunit gamma 1
chr15_-_42783303 0.126 ENST00000565380.1
ENST00000564754.1
ZNF106

zinc finger protein 106

chr10_+_14880287 0.124 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chrX_+_44732757 0.124 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr3_+_179322481 0.123 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr12_-_114843889 0.121 ENST00000405440.2
TBX5
T-box 5
chr14_+_27342334 0.121 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1

RP11-384J4.1

chr17_-_56358287 0.121 ENST00000225275.3
ENST00000340482.3
MPO

myeloperoxidase

chr1_-_1711508 0.119 ENST00000378625.1
NADK
NAD kinase
chr22_+_23213658 0.119 ENST00000390318.2
IGLV4-3
immunoglobulin lambda variable 4-3
chr16_-_70729496 0.117 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr16_+_30675654 0.116 ENST00000287468.5
ENST00000395073.2
FBRS

fibrosin

chr8_+_145149930 0.116 ENST00000318911.4
CYC1
cytochrome c-1
chr3_+_51741072 0.115 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr6_-_31628512 0.115 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr17_+_79679299 0.114 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr7_-_81399411 0.112 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr20_-_33999766 0.112 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
UQCC1











ubiquinol-cytochrome c reductase complex assembly factor 1











chr1_-_241683001 0.110 ENST00000366560.3
FH
fumarate hydratase
chrX_-_63005405 0.108 ENST00000374878.1
ENST00000437457.2
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr9_+_33629119 0.108 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr12_+_7169887 0.102 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr14_+_22320634 0.101 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr2_+_219745020 0.101 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr15_+_43985725 0.101 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr3_-_49377499 0.100 ENST00000265560.4
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr10_-_50122277 0.099 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chr20_+_30865429 0.098 ENST00000375712.3
KIF3B
kinesin family member 3B
chr12_+_120875887 0.097 ENST00000229379.2
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1
chr16_-_66952742 0.095 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16


cadherin 16, KSP-cadherin


chr5_-_176981417 0.095 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B


family with sequence similarity 193, member B


chr19_+_45394477 0.094 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40




translocase of outer mitochondrial membrane 40 homolog (yeast)




chr17_+_79670386 0.094 ENST00000541223.1
ENST00000571730.1
ENST00000333676.3
SLC25A10
SLC25A10
MRPL12
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
mitochondrial ribosomal protein L12
chr4_-_40517984 0.093 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr9_-_115983641 0.089 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr6_-_107077347 0.089 ENST00000369063.3
ENST00000539449.1
RTN4IP1

reticulon 4 interacting protein 1

chr16_-_49698136 0.087 ENST00000535559.1
ZNF423
zinc finger protein 423
chr17_-_42988004 0.087 ENST00000586125.1
ENST00000591880.1
GFAP

glial fibrillary acidic protein

chr3_-_10028366 0.087 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chrX_+_69454505 0.084 ENST00000374521.3
AWAT1
acyl-CoA wax alcohol acyltransferase 1
chr2_+_109237717 0.084 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_198365122 0.080 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr3_+_113465866 0.079 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr10_+_22605374 0.078 ENST00000448361.1
COMMD3
COMM domain containing 3
chr14_-_92572894 0.078 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3













ataxin 3













chr4_-_140527848 0.077 ENST00000608795.1
ENST00000608958.1
SETD7

SET domain containing (lysine methyltransferase) 7

chr17_+_45973516 0.077 ENST00000376741.4
SP2
Sp2 transcription factor
chr2_+_198365095 0.077 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr3_-_52860850 0.076 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr7_-_105029812 0.075 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr17_+_79679369 0.074 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr22_+_30821732 0.074 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr4_+_20255123 0.072 ENST00000504154.1
ENST00000273739.5
SLIT2

slit homolog 2 (Drosophila)

chr10_+_14880157 0.071 ENST00000378372.3
HSPA14
heat shock 70kDa protein 14
chr19_+_45251804 0.070 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr10_+_5932174 0.069 ENST00000362091.4
FBXO18
F-box protein, helicase, 18
chr20_+_13765596 0.068 ENST00000378106.5
ENST00000463598.1
NDUFAF5

NADH dehydrogenase (ubiquinone) complex I, assembly factor 5

chr8_-_100905925 0.067 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr8_-_100905850 0.067 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C




cytochrome c oxidase subunit VIc




chr16_+_11038345 0.064 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr20_+_44421137 0.064 ENST00000415790.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr11_+_34938119 0.063 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX


pyruvate dehydrogenase complex, component X


chr19_+_54606145 0.062 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3





NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa





chr10_+_51371390 0.062 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
TIMM23B



translocase of inner mitochondrial membrane 23 homolog B (yeast)



chr3_+_138340049 0.059 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr16_-_30537839 0.059 ENST00000380412.5
ZNF768
zinc finger protein 768
chr12_+_51818586 0.058 ENST00000394856.1
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr4_-_140216948 0.057 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr2_-_25194476 0.056 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_+_201924619 0.056 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr12_-_56753858 0.056 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2


signal transducer and activator of transcription 2, 113kDa


chr7_-_91875109 0.056 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1












KRIT1, ankyrin repeat containing












chr3_-_49459878 0.055 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT


aminomethyltransferase


chr7_+_148287657 0.055 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr5_+_218356 0.054 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA


succinate dehydrogenase complex, subunit A, flavoprotein (Fp)


chr11_+_67798114 0.053 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8



NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)



chr9_+_129567282 0.052 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
ZBTB43


zinc finger and BTB domain containing 43


chr14_+_77228532 0.051 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr6_-_76072719 0.051 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr8_+_145582633 0.051 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr1_-_205904950 0.050 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr15_-_55562582 0.049 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr10_-_120938303 0.049 ENST00000356951.3
ENST00000298510.2
PRDX3

peroxiredoxin 3

chr2_+_119981384 0.049 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP3






STEAP family member 3, metalloreductase






chr2_+_103378472 0.049 ENST00000412401.2
TMEM182
transmembrane protein 182
chr1_-_205719295 0.048 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr10_+_22605304 0.048 ENST00000456711.1
ENST00000444869.1
ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
COMMD3

COMMD3-BMI1


COMM domain containing 3

COMMD3-BMI1 readthrough


chr1_-_154164534 0.047 ENST00000271850.7
ENST00000368530.2
TPM3

tropomyosin 3

chr5_-_139937895 0.046 ENST00000336283.6
SRA1
steroid receptor RNA activator 1
chr12_-_57039739 0.046 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B





ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide





chrX_-_150067173 0.046 ENST00000370377.3
ENST00000320893.6
CD99L2

CD99 molecule-like 2

chr18_-_19284724 0.044 ENST00000580981.1
ENST00000289119.2
ABHD3

abhydrolase domain containing 3

chr3_-_167452298 0.044 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10


programmed cell death 10


chr1_+_45140360 0.043 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228




chromosome 1 open reading frame 228




chr4_+_26321284 0.043 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr12_+_51818749 0.042 ENST00000514353.3
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3 0.9 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.9 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.4 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.6 GO:0061525 hindgut development(GO:0061525)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.2 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0090024 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 2.4 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 1.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)
0.0 1.1 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 0.6 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 2.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.5 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0004040 amidase activity(GO:0004040)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.0 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.4 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation