Motif ID: NR3C1

Z-value: 0.653


Transcription factors associated with NR3C1:

Gene SymbolEntrez IDGene Name
NR3C1 ENSG00000113580.10 NR3C1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR3C1hg19_v2_chr5_-_142782862_1427828940.193.7e-01Click!


Activity profile for motif NR3C1.

activity profile for motif NR3C1


Sorted Z-values histogram for motif NR3C1

Sorted Z-values for motif NR3C1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153066998 1.077 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr1_-_153013588 1.064 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr21_-_47352477 1.063 ENST00000593412.1
PRED62
Uncharacterized protein
chr17_-_38859996 0.891 ENST00000264651.2
KRT24
keratin 24
chr10_-_5541525 0.856 ENST00000380332.3
CALML5
calmodulin-like 5
chr1_-_153433120 0.838 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr2_-_113594279 0.799 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr5_+_33936491 0.784 ENST00000330120.3
RXFP3
relaxin/insulin-like family peptide receptor 3
chr17_-_39553844 0.763 ENST00000251645.2
KRT31
keratin 31
chr19_+_54926601 0.744 ENST00000301194.4
TTYH1
tweety family member 1
chr1_+_152956549 0.732 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr2_-_31637560 0.714 ENST00000379416.3
XDH
xanthine dehydrogenase
chr19_-_51456344 0.704 ENST00000336334.3
ENST00000593428.1
KLK5

kallikrein-related peptidase 5

chr19_-_51456321 0.699 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr1_-_27816556 0.695 ENST00000536657.1
WASF2
WAS protein family, member 2
chr8_-_125740514 0.668 ENST00000325064.5
ENST00000518547.1
MTSS1

metastasis suppressor 1

chr6_+_38690622 0.650 ENST00000327475.6
DNAH8
dynein, axonemal, heavy chain 8
chrX_+_55246818 0.647 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr7_+_76054224 0.636 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr4_+_75310851 0.621 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr1_-_17304771 0.615 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr2_+_11817713 0.612 ENST00000449576.2
LPIN1
lipin 1
chr2_+_11864458 0.603 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1


lipin 1


chr2_+_233925064 0.600 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr19_+_54926621 0.599 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1



tweety family member 1



chr17_-_71410794 0.594 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr5_-_39219705 0.593 ENST00000351578.6
FYB
FYN binding protein
chr15_-_81616446 0.590 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr4_+_75311019 0.552 ENST00000502307.1
AREG
amphiregulin
chr12_+_110011571 0.544 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr11_-_66675371 0.543 ENST00000393955.2
PC
pyruvate carboxylase
chr18_+_61442629 0.540 ENST00000398019.2
ENST00000540675.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr2_+_234637754 0.530 ENST00000609767.1
ENST00000482026.1
UGT1A1
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A3
chr8_-_125577940 0.526 ENST00000519168.1
ENST00000395508.2
MTSS1

metastasis suppressor 1

chr8_-_125740730 0.516 ENST00000354184.4
MTSS1
metastasis suppressor 1
chr12_-_48164812 0.514 ENST00000549151.1
ENST00000548919.1
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr14_+_105190514 0.507 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr12_-_110486348 0.499 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
C12orf76


chromosome 12 open reading frame 76


chr9_+_75263565 0.499 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr22_+_24322322 0.495 ENST00000215780.5
ENST00000402588.3
GSTT2

glutathione S-transferase theta 2

chr14_-_106805716 0.493 ENST00000438142.2
IGHV4-31
immunoglobulin heavy variable 4-31
chr1_-_38218577 0.489 ENST00000540011.1
EPHA10
EPH receptor A10
chr13_+_78109804 0.486 ENST00000535157.1
SCEL
sciellin
chr1_-_24469602 0.485 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr5_-_39219641 0.477 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB



FYN binding protein



chr11_-_105948129 0.477 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr15_+_40643227 0.476 ENST00000448599.2
PHGR1
proline/histidine/glycine-rich 1
chr14_-_107283278 0.476 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr20_+_60174827 0.473 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr20_+_62327996 0.466 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr6_-_133079022 0.463 ENST00000525289.1
ENST00000326499.6
VNN2

vanin 2

chrX_+_64887512 0.462 ENST00000360270.5
MSN
moesin
chr18_-_33077556 0.458 ENST00000589273.1
ENST00000586489.1
INO80C

INO80 complex subunit C

chr1_-_152552980 0.456 ENST00000368787.3
LCE3D
late cornified envelope 3D
chr2_-_42991257 0.441 ENST00000378661.2
OXER1
oxoeicosanoid (OXE) receptor 1
chr4_+_75480629 0.440 ENST00000380846.3
AREGB
amphiregulin B
chr19_-_43382142 0.438 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr7_+_40174565 0.434 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10





succinylCoA:glutarate-CoA transferase





chr4_-_48136217 0.433 ENST00000264316.4
TXK
TXK tyrosine kinase
chr19_+_16308711 0.429 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1


adaptor-related protein complex 1, mu 1 subunit


chrX_-_119249819 0.428 ENST00000217999.2
RHOXF1
Rhox homeobox family, member 1
chr18_-_48346298 0.420 ENST00000398439.3
MRO
maestro
chr7_-_100860851 0.418 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr13_+_78109884 0.416 ENST00000377246.3
ENST00000349847.3
SCEL

sciellin

chr17_-_34756219 0.414 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chrX_+_2984874 0.412 ENST00000359361.2
ARSF
arylsulfatase F
chr13_+_32838801 0.409 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr19_+_15751689 0.408 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
CYP4F3


cytochrome P450, family 4, subfamily F, polypeptide 3


chr14_+_94640633 0.405 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr17_+_73975292 0.400 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1




TEN1 CST complex subunit




chr11_-_6341724 0.396 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr1_-_153521597 0.389 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr17_+_40704938 0.386 ENST00000225929.5
HSD17B1
hydroxysteroid (17-beta) dehydrogenase 1
chr11_-_2924970 0.385 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr15_+_28624878 0.381 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr8_-_101661887 0.380 ENST00000311812.2
SNX31
sorting nexin 31
chr7_-_76255444 0.379 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr9_-_21305312 0.378 ENST00000259555.4
IFNA5
interferon, alpha 5
chr3_+_42727011 0.377 ENST00000287777.4
KLHL40
kelch-like family member 40
chr11_-_61646054 0.375 ENST00000527379.1
FADS3
fatty acid desaturase 3
chr8_+_54793454 0.373 ENST00000276500.4
RGS20
regulator of G-protein signaling 20
chr19_+_5823813 0.372 ENST00000303212.2
NRTN
neurturin
chr17_+_74380683 0.371 ENST00000592299.1
ENST00000590959.1
ENST00000323374.4
SPHK1


sphingosine kinase 1


chr7_-_93519471 0.370 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr11_+_57365150 0.370 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr8_+_7752151 0.369 ENST00000302247.2
DEFB4A
defensin, beta 4A
chr8_+_128427857 0.369 ENST00000391675.1
POU5F1B
POU class 5 homeobox 1B
chr20_-_23586513 0.367 ENST00000376971.3
CST9
cystatin 9 (testatin)
chr19_-_16008880 0.366 ENST00000011989.7
ENST00000221700.6
CYP4F2

cytochrome P450, family 4, subfamily F, polypeptide 2

chr2_+_27719697 0.365 ENST00000264717.2
ENST00000424318.2
GCKR

glucokinase (hexokinase 4) regulator

chr11_-_6341844 0.364 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr8_+_54793425 0.362 ENST00000522225.1
RGS20
regulator of G-protein signaling 20
chr18_+_9885760 0.362 ENST00000536353.2
ENST00000584255.1
TXNDC2

thioredoxin domain containing 2 (spermatozoa)

chr22_-_44287875 0.360 ENST00000438734.1
ENST00000597664.1
ENST00000216177.4
ENST00000593866.1
ENST00000381198.2
PNPLA5




patatin-like phospholipase domain containing 5




chr3_+_12330560 0.359 ENST00000397026.2
PPARG
peroxisome proliferator-activated receptor gamma
chr10_+_17270214 0.359 ENST00000544301.1
VIM
vimentin
chr18_+_56530136 0.357 ENST00000591083.1
ZNF532
zinc finger protein 532
chr2_-_89545079 0.356 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr1_-_153283194 0.351 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr10_-_90967063 0.350 ENST00000371852.2
CH25H
cholesterol 25-hydroxylase
chr1_+_22979676 0.350 ENST00000432749.2
ENST00000314933.6
C1QB

complement component 1, q subcomponent, B chain

chr7_+_143318020 0.349 ENST00000444908.2
ENST00000518791.1
ENST00000411497.2
FAM115C


family with sequence similarity 115, member C


chr6_-_109777128 0.348 ENST00000358807.3
ENST00000358577.3
MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr10_-_135090360 0.345 ENST00000486609.1
ENST00000445355.3
ENST00000485491.2
ADAM8


ADAM metallopeptidase domain 8


chr17_-_16472483 0.345 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287


zinc finger protein 287


chr4_-_89744314 0.344 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr12_+_128399965 0.343 ENST00000540882.1
ENST00000542089.1
LINC00507

long intergenic non-protein coding RNA 507

chr15_+_90728145 0.341 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr17_+_74381343 0.341 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr10_-_105845674 0.340 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr8_+_91013577 0.339 ENST00000220764.2
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr1_-_55089191 0.336 ENST00000302250.2
ENST00000371304.2
FAM151A

family with sequence similarity 151, member A

chr9_+_131683174 0.335 ENST00000372592.3
ENST00000428610.1
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr10_+_696000 0.335 ENST00000381489.5
PRR26
proline rich 26
chr5_+_135394840 0.334 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr8_+_26247878 0.334 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_-_89278535 0.333 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr19_-_2041159 0.332 ENST00000589441.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_-_153521714 0.329 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr4_-_89744457 0.329 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr19_+_35485682 0.327 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr14_+_94640671 0.324 ENST00000328839.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr3_-_182833863 0.323 ENST00000492597.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr19_-_54876558 0.321 ENST00000391742.2
ENST00000434277.2
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr4_-_89744365 0.317 ENST00000513837.1
ENST00000503556.1
FAM13A

family with sequence similarity 13, member A

chr22_-_37880543 0.316 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_-_66417107 0.315 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr2_-_231825668 0.314 ENST00000392039.2
GPR55
G protein-coupled receptor 55
chr11_+_117857063 0.311 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA


interleukin 10 receptor, alpha


chr9_+_116267536 0.311 ENST00000374136.1
RGS3
regulator of G-protein signaling 3
chr10_-_17659234 0.311 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_-_56848426 0.310 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr18_+_34124507 0.309 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr1_-_27816641 0.308 ENST00000430629.2
WASF2
WAS protein family, member 2
chr10_+_120863587 0.308 ENST00000535029.1
ENST00000361432.2
ENST00000544016.1
FAM45A


family with sequence similarity 45, member A


chr1_-_9129598 0.305 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_-_107590383 0.304 ENST00000525934.1
ENST00000531293.1
SLN

sarcolipin

chr14_-_81408063 0.300 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr10_-_135090338 0.300 ENST00000415217.3
ADAM8
ADAM metallopeptidase domain 8
chr2_+_240323439 0.298 ENST00000428471.1
ENST00000413029.1
AC062017.1

Uncharacterized protein

chr11_-_85376121 0.298 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr17_+_7905912 0.296 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr17_+_7344057 0.296 ENST00000575398.1
ENST00000575082.1
FGF11

fibroblast growth factor 11

chr1_+_171060018 0.295 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
FMO3




flavin containing monooxygenase 3




chr22_+_23248512 0.294 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr11_-_105948040 0.291 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr17_-_6983550 0.290 ENST00000576617.1
ENST00000416562.2
CLEC10A

C-type lectin domain family 10, member A

chr11_-_118135160 0.289 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr10_-_76868931 0.287 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13




dual specificity phosphatase 13




chr2_-_71062938 0.287 ENST00000410009.3
CD207
CD207 molecule, langerin
chr15_+_67430339 0.286 ENST00000439724.3
SMAD3
SMAD family member 3
chr2_+_234621551 0.286 ENST00000373414.3
ENST00000608381.1
UGT1A5
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A5
UDP glucuronosyltransferase 1 family, polypeptide A8
chr15_+_90792760 0.286 ENST00000339615.5
ENST00000438251.1
TTLL13

tubulin tyrosine ligase-like family, member 13

chr2_+_89975669 0.286 ENST00000474213.1
IGKV2D-30
immunoglobulin kappa variable 2D-30
chr15_-_22448819 0.285 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr17_-_6983594 0.285 ENST00000571664.1
ENST00000254868.4
CLEC10A

C-type lectin domain family 10, member A

chr7_-_121784285 0.285 ENST00000417368.2
AASS
aminoadipate-semialdehyde synthase
chr15_+_41099788 0.285 ENST00000299173.10
ENST00000566407.1
ZFYVE19

zinc finger, FYVE domain containing 19

chrX_+_17755563 0.284 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1



sex comb on midleg-like 1 (Drosophila)



chr1_+_22979474 0.282 ENST00000509305.1
C1QB
complement component 1, q subcomponent, B chain
chr9_-_107690420 0.281 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr22_+_39410088 0.281 ENST00000361441.4
APOBEC3C
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
chr17_+_36286047 0.279 ENST00000539424.1
TBC1D3F
TBC1 domain family, member 3F
chr17_-_57232525 0.276 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2



spindle and kinetochore associated complex subunit 2



chr19_+_51152702 0.275 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr19_+_11670245 0.274 ENST00000585493.1
ZNF627
zinc finger protein 627
chr12_+_53443963 0.272 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr10_+_5005598 0.272 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr3_-_149095652 0.269 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr19_-_41934635 0.269 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr19_-_10445399 0.269 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr3_-_151047327 0.268 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr8_-_143696833 0.268 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr12_+_8666126 0.266 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr2_+_90458201 0.266 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chrX_+_2609317 0.262 ENST00000381187.3
ENST00000381184.1
CD99

CD99 molecule

chr17_-_36347030 0.262 ENST00000518551.1
TBC1D3
TBC1 domain family, member 3
chr11_+_2920951 0.261 ENST00000347936.2
SLC22A18
solute carrier family 22, member 18
chr22_+_23243156 0.260 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chrX_+_135618258 0.259 ENST00000440515.1
ENST00000456412.1
VGLL1

vestigial like 1 (Drosophila)

chr1_-_47069886 0.258 ENST00000371946.4
ENST00000371945.4
ENST00000428112.2
ENST00000529170.1
MKNK1



MAP kinase interacting serine/threonine kinase 1



chr17_-_76123101 0.257 ENST00000392467.3
TMC6
transmembrane channel-like 6
chr16_-_10652993 0.257 ENST00000536829.1
EMP2
epithelial membrane protein 2
chrX_-_38080077 0.256 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX



sushi-repeat containing protein, X-linked



chr3_-_98235962 0.255 ENST00000513873.1
CLDND1
claudin domain containing 1
chr22_-_24303340 0.255 ENST00000404172.3
ENST00000290765.4
GSTT2B

glutathione S-transferase theta 2B (gene/pseudogene)

chr14_-_106816253 0.254 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr10_+_99332198 0.254 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2


ankyrin repeat domain 2 (stretch responsive muscle)


chr14_-_23426270 0.252 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr16_-_67517716 0.252 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr11_-_2924720 0.251 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr1_-_89641680 0.251 ENST00000294671.2
GBP7
guanylate binding protein 7
chr14_-_106781017 0.250 ENST00000390612.2
IGHV4-28
immunoglobulin heavy variable 4-28
chr10_+_99332529 0.249 ENST00000455090.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr17_-_34502410 0.249 ENST00000398801.3
TBC1D3B
TBC1 domain family, member 3B
chrX_+_55246771 0.248 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chr14_-_107211459 0.247 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr3_+_107602030 0.246 ENST00000494231.1
LINC00636
long intergenic non-protein coding RNA 636
chr13_+_112721913 0.246 ENST00000330949.1
SOX1
SRY (sex determining region Y)-box 1
chr14_-_106668095 0.246 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0035419 activation of MAPK activity involved in innate immune response(GO:0035419)
0.3 1.7 GO:0030035 microspike assembly(GO:0030035)
0.3 0.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.7 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 1.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.6 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.2 1.0 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 0.6 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.5 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.7 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 1.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.5 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 1.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.8 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 0.5 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 1.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.3 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.3 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.1 0.4 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.7 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.2 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.4 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.2 GO:0019860 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:0071335 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 3.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 1.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.5 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.0 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0072678 T cell migration(GO:0072678)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490) regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.3 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0072255 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.2 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0097051 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.5 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0001776 leukocyte homeostasis(GO:0001776) lymphocyte homeostasis(GO:0002260)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.2 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.0 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 1.7 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0007260 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.0 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.3 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071065 dense core granule membrane(GO:0032127) alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 1.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.6 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.6 GO:0005602 complement component C1 complex(GO:0005602)
0.1 4.3 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 2.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.0 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0030120 vesicle coat(GO:0030120)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 0.8 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 1.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.5 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.1 0.3 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.1 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.9 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.7 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.8 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.9 GO:0032052 bile acid binding(GO:0032052)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0019862 IgA binding(GO:0019862)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0017153 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 3.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.0 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 1.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.0 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.2 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.3 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.2 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.9 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.1 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline