Motif ID: NR2E3

Z-value: 0.427


Transcription factors associated with NR2E3:

Gene SymbolEntrez IDGene Name
NR2E3 ENSG00000031544.10 NR2E3



Activity profile for motif NR2E3.

activity profile for motif NR2E3


Sorted Z-values histogram for motif NR2E3

Sorted Z-values for motif NR2E3



Network of associatons between targets according to the STRING database.



First level regulatory network of NR2E3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_1633755 0.804 ENST00000545662.1
WDR81
WD repeat domain 81
chr1_+_47264711 0.594 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1


cytochrome P450, family 4, subfamily B, polypeptide 1


chr2_-_216257849 0.584 ENST00000456923.1
FN1
fibronectin 1
chrX_-_132887729 0.490 ENST00000406757.2
GPC3
glypican 3
chr3_-_195310802 0.455 ENST00000421243.1
ENST00000453131.1
APOD

apolipoprotein D

chr17_+_12692774 0.437 ENST00000379672.5
ENST00000340825.3
ARHGAP44

Rho GTPase activating protein 44

chr20_+_56725952 0.437 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr8_+_40010989 0.436 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr4_-_110723134 0.434 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr4_-_110723194 0.432 ENST00000394635.3
CFI
complement factor I
chr11_-_108408895 0.406 ENST00000443411.1
ENST00000533052.1
EXPH5

exophilin 5

chr4_-_110723335 0.398 ENST00000394634.2
CFI
complement factor I
chr1_-_146697185 0.365 ENST00000533174.1
ENST00000254090.4
FMO5

flavin containing monooxygenase 5

chr3_-_186262166 0.357 ENST00000307944.5
CRYGS
crystallin, gamma S
chr17_+_68165657 0.348 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_189060573 0.345 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr22_-_36013368 0.323 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr17_-_6735035 0.312 ENST00000338694.2
TEKT1
tektin 1
chr17_-_6735012 0.309 ENST00000535086.1
TEKT1
tektin 1
chr12_+_56661461 0.301 ENST00000546544.1
ENST00000553234.1
COQ10A

coenzyme Q10 homolog A (S. cerevisiae)

chr12_+_56661033 0.296 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr7_-_121944491 0.269 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr3_+_181429704 0.268 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr2_+_149894968 0.265 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chrX_-_65259914 0.262 ENST00000374737.4
ENST00000455586.2
VSIG4

V-set and immunoglobulin domain containing 4

chr8_+_104831554 0.246 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr11_-_40315640 0.246 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr10_-_103603523 0.243 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr16_+_29471210 0.237 ENST00000360423.7
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr14_+_58754751 0.224 ENST00000598233.1
AL132989.1
AL132989.1
chr17_+_68100989 0.223 ENST00000585558.1
ENST00000392670.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr16_+_30210552 0.220 ENST00000338971.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr11_+_111789580 0.220 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr15_+_78558523 0.218 ENST00000446172.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr11_+_1891380 0.218 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
LSP1


lymphocyte-specific protein 1


chrX_-_65259900 0.212 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr9_+_74764278 0.210 ENST00000238018.4
ENST00000376989.3
GDA

guanine deaminase

chr11_-_5276008 0.207 ENST00000336906.4
HBG2
hemoglobin, gamma G
chr11_-_5271122 0.206 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr4_-_23891693 0.205 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr22_+_24105394 0.205 ENST00000305199.5
ENST00000382821.3
C22orf15

chromosome 22 open reading frame 15

chr5_-_137368708 0.204 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr14_+_78870030 0.203 ENST00000553631.1
ENST00000554719.1
NRXN3

neurexin 3

chr1_-_112106578 0.202 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr1_+_61330931 0.200 ENST00000371191.1
NFIA
nuclear factor I/A
chr4_-_25865159 0.200 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr5_+_161274940 0.199 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_-_156534754 0.199 ENST00000472943.1
ENST00000473352.1
LINC00886

long intergenic non-protein coding RNA 886

chr2_+_106682103 0.196 ENST00000238044.3
C2orf40
chromosome 2 open reading frame 40
chr3_+_69915385 0.196 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr17_-_10421853 0.195 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr6_-_29648887 0.194 ENST00000376883.1
ZFP57
ZFP57 zinc finger protein
chr12_-_71182695 0.192 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr16_-_12184159 0.190 ENST00000312019.2
RP11-276H1.3
RP11-276H1.3
chr4_-_23891658 0.190 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_-_150473127 0.190 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chrX_+_50653784 0.182 ENST00000252677.3
BMP15
bone morphogenetic protein 15
chr5_+_59783941 0.180 ENST00000506884.1
ENST00000504876.2
PART1

prostate androgen-regulated transcript 1 (non-protein coding)

chr4_-_186317034 0.180 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr3_+_141105705 0.178 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_-_169626104 0.177 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1

CTB-27N1.1

chr1_-_112106556 0.173 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr19_-_40724246 0.173 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr2_+_106682135 0.172 ENST00000437659.1
C2orf40
chromosome 2 open reading frame 40
chr3_+_113616317 0.171 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr9_+_74764340 0.167 ENST00000376986.1
ENST00000358399.3
GDA

guanine deaminase

chr2_-_175712270 0.167 ENST00000295497.7
ENST00000444394.1
CHN1

chimerin 1

chr12_+_51785057 0.165 ENST00000535225.2
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr6_-_76203345 0.165 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chrX_-_102565858 0.164 ENST00000449185.1
ENST00000536889.1
BEX2

brain expressed X-linked 2

chr19_+_35396219 0.164 ENST00000595783.1
CTC-523E23.6
CTC-523E23.6
chr21_+_43823983 0.164 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A



ubiquitin associated and SH3 domain containing A



chr7_-_137028534 0.161 ENST00000348225.2
PTN
pleiotrophin
chr8_+_36641842 0.160 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr22_-_37172111 0.157 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27


intraflagellar transport 27 homolog (Chlamydomonas)


chr1_+_149858461 0.156 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr16_+_50776021 0.156 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD


cylindromatosis (turban tumor syndrome)


chr3_+_148508845 0.154 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr11_-_32452357 0.154 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr22_-_37172191 0.154 ENST00000340630.5
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr11_-_26588634 0.152 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr11_+_64216546 0.151 ENST00000316124.2
AP003774.4
HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
chr4_+_160188889 0.150 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr20_+_48909240 0.150 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr5_-_76935513 0.150 ENST00000306422.3
OTP
orthopedia homeobox
chr8_+_103563792 0.147 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr3_-_65583561 0.146 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr11_-_33913708 0.146 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr22_+_41865109 0.145 ENST00000216254.4
ENST00000396512.3
ACO2

aconitase 2, mitochondrial

chr3_+_154958715 0.144 ENST00000462531.1
ENST00000490497.1
RP11-451G4.1

RP11-451G4.1

chr6_+_54173227 0.144 ENST00000259782.4
ENST00000370864.3
TINAG

tubulointerstitial nephritis antigen

chr19_+_37808778 0.142 ENST00000544914.1
ENST00000589188.1
HKR1

HKR1, GLI-Kruppel zinc finger family member

chr11_+_76745385 0.142 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
B3GNT6


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)


chr9_-_90589586 0.140 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr1_+_87797351 0.140 ENST00000370542.1
LMO4
LIM domain only 4
chr4_+_170581213 0.140 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr9_-_90589402 0.140 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chr15_-_58306295 0.140 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_61547405 0.137 ENST00000371189.4
NFIA
nuclear factor I/A
chr16_-_75569068 0.136 ENST00000336257.3
ENST00000565039.1
CHST5

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5

chr11_-_10590238 0.136 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr8_+_86121448 0.135 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr14_+_74035763 0.135 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr1_+_153190053 0.134 ENST00000368744.3
PRR9
proline rich 9
chr7_-_137028498 0.134 ENST00000393083.2
PTN
pleiotrophin
chr12_+_56477093 0.132 ENST00000549672.1
ENST00000415288.2
ERBB3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

chr15_-_65067773 0.132 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr1_+_107599267 0.131 ENST00000361318.5
ENST00000370078.1
PRMT6

protein arginine methyltransferase 6

chr1_-_43282906 0.130 ENST00000372521.4
CCDC23
coiled-coil domain containing 23
chr8_+_74903580 0.130 ENST00000284818.2
ENST00000518893.1
LY96

lymphocyte antigen 96

chr13_-_38443860 0.130 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr11_+_71640071 0.130 ENST00000533380.1
ENST00000393713.3
ENST00000545854.1
RNF121


ring finger protein 121


chr15_+_76629064 0.130 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr6_+_21593972 0.129 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr14_+_74004051 0.129 ENST00000557556.1
ACOT1
acyl-CoA thioesterase 1
chr2_+_54558004 0.129 ENST00000405749.1
ENST00000398634.2
ENST00000447328.1
C2orf73


chromosome 2 open reading frame 73


chr6_-_25874440 0.129 ENST00000361703.6
ENST00000397060.4
SLC17A3

solute carrier family 17 (organic anion transporter), member 3

chr6_+_12007897 0.128 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr11_+_71640112 0.128 ENST00000530137.1
RNF121
ring finger protein 121
chr5_-_20575959 0.128 ENST00000507958.1
CDH18
cadherin 18, type 2
chr5_+_140571902 0.125 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr12_-_91539918 0.124 ENST00000548218.1
DCN
decorin
chr6_-_76203454 0.124 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr18_+_13611763 0.124 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr1_+_61547894 0.123 ENST00000403491.3
NFIA
nuclear factor I/A
chr4_-_2264015 0.123 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr20_-_40247133 0.123 ENST00000373233.3
ENST00000309279.7
CHD6

chromodomain helicase DNA binding protein 6

chr15_-_52587945 0.122 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr4_+_159727272 0.122 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr3_+_160394940 0.121 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr11_-_41481135 0.121 ENST00000528697.1
ENST00000530763.1
LRRC4C

leucine rich repeat containing 4C

chr11_+_65266507 0.120 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr8_+_101170563 0.119 ENST00000520508.1
ENST00000388798.2
SPAG1

sperm associated antigen 1

chr1_+_65775204 0.118 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_-_21792838 0.117 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr15_+_81591757 0.116 ENST00000558332.1
IL16
interleukin 16
chr1_+_166958497 0.115 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr4_+_88896819 0.115 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1



secreted phosphoprotein 1



chr8_+_77318769 0.115 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr18_-_53069419 0.115 ENST00000570177.2
TCF4
transcription factor 4
chr7_-_130080818 0.114 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
CEP41


centrosomal protein 41kDa


chr19_+_3762645 0.113 ENST00000330133.4
MRPL54
mitochondrial ribosomal protein L54
chr11_+_66406149 0.113 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
RBM4






RNA binding motif protein 4






chr3_-_165555200 0.112 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr20_+_58533471 0.111 ENST00000244047.5
ENST00000348616.4
CDH26

cadherin 26

chr5_-_13944652 0.111 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chrX_-_24665208 0.110 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_-_79082867 0.110 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chrX_+_133941218 0.110 ENST00000370784.4
ENST00000370785.3
FAM122C

family with sequence similarity 122C

chr11_+_30252549 0.110 ENST00000254122.3
ENST00000417547.1
FSHB

follicle stimulating hormone, beta polypeptide

chr16_+_56995854 0.109 ENST00000566128.1
CETP
cholesteryl ester transfer protein, plasma
chr17_-_62208169 0.108 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr5_+_161275320 0.107 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_167298281 0.107 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr14_+_23654525 0.106 ENST00000399910.1
ENST00000492621.1
C14orf164

chromosome 14 open reading frame 164

chr21_-_34185944 0.105 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr14_+_74003818 0.104 ENST00000311148.4
ACOT1
acyl-CoA thioesterase 1
chr6_-_79944336 0.104 ENST00000344726.5
ENST00000275036.7
HMGN3

high mobility group nucleosomal binding domain 3

chr20_-_45318230 0.103 ENST00000372114.3
TP53RK
TP53 regulating kinase
chrM_+_12331 0.103 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr12_-_8043736 0.102 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr19_-_41870026 0.101 ENST00000243578.3
B9D2
B9 protein domain 2
chr20_-_56286479 0.099 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr19_-_40596767 0.099 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
ZNF780A


zinc finger protein 780A


chr11_+_121447469 0.099 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr6_-_152639479 0.099 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_161274685 0.098 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_-_3584430 0.098 ENST00000438482.1
ENST00000422961.1
AC108488.4

AC108488.4

chr8_-_37457350 0.097 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr21_+_27011584 0.096 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2


junctional adhesion molecule 2


chrX_+_72667090 0.095 ENST00000373514.2
CDX4
caudal type homeobox 4
chr12_-_45269430 0.095 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr6_-_170599561 0.094 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr5_-_139422654 0.093 ENST00000289409.4
ENST00000358522.3
ENST00000378238.4
ENST00000289422.7
ENST00000361474.1
ENST00000545385.1
ENST00000394770.1
ENST00000541337.1
NRG2







neuregulin 2







chr19_+_3721719 0.092 ENST00000589378.1
ENST00000382008.3
TJP3

tight junction protein 3

chr17_-_41977964 0.092 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr10_-_103603568 0.092 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr12_+_110906169 0.091 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr19_-_9546177 0.091 ENST00000592292.1
ENST00000588221.1
ZNF266

zinc finger protein 266

chr12_+_104680659 0.090 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1





thioredoxin reductase 1





chr15_-_58571445 0.090 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_+_17298255 0.089 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
NUCB2


nucleobindin 2


chr12_+_104458235 0.089 ENST00000229330.4
HCFC2
host cell factor C2
chr4_-_153332886 0.088 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_+_17248418 0.088 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr11_+_17298297 0.087 ENST00000529010.1
NUCB2
nucleobindin 2
chr4_-_170948361 0.087 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr11_+_65479702 0.087 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr7_-_19813192 0.087 ENST00000422233.1
ENST00000433641.1
TMEM196

transmembrane protein 196

chr19_+_3762703 0.086 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr15_+_65914347 0.086 ENST00000544319.2
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr1_+_45140360 0.085 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228




chromosome 1 open reading frame 228




chr19_+_46498704 0.085 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61


coiled-coil domain containing 61


chr22_-_41864662 0.085 ENST00000216252.3
PHF5A
PHD finger protein 5A
chr19_-_54693401 0.084 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr15_+_43803143 0.084 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr2_-_158732340 0.084 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1



activin A receptor, type I



chr2_+_232573208 0.083 ENST00000409115.3
PTMA
prothymosin, alpha
chr9_-_140484917 0.083 ENST00000298585.2
ZMYND19
zinc finger, MYND-type containing 19
chr9_-_116102562 0.082 ENST00000374193.4
ENST00000465979.1
WDR31

WD repeat domain 31


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.6 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.5 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.4 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.2 GO:0018032 protein amidation(GO:0018032)
0.1 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0072299 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.6 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102) response to isolation stress(GO:0035900)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.0 GO:1904604 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation