Motif ID: NKX2-5

Z-value: 0.464


Transcription factors associated with NKX2-5:

Gene SymbolEntrez IDGene Name
NKX2-5 ENSG00000183072.9 NKX2-5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX2-5hg19_v2_chr5_-_172662303_172662360-0.077.4e-01Click!


Activity profile for motif NKX2-5.

activity profile for motif NKX2-5


Sorted Z-values histogram for motif NKX2-5

Sorted Z-values for motif NKX2-5



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_150254936 0.403 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr17_-_29641084 0.399 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr4_+_81118647 0.376 ENST00000415738.2
PRDM8
PR domain containing 8
chr11_+_76813886 0.357 ENST00000529803.1
OMP
olfactory marker protein
chr9_+_118950325 0.335 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_-_111314230 0.313 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr17_-_8059638 0.302 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1


period circadian clock 1


chr10_-_7513904 0.296 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr14_+_21467414 0.281 ENST00000554422.1
ENST00000298681.4
SLC39A2

solute carrier family 39 (zinc transporter), member 2

chr7_-_122339162 0.271 ENST00000340112.2
RNF133
ring finger protein 133
chr4_-_153700864 0.261 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr14_+_78227105 0.242 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178



chromosome 14 open reading frame 178



chr17_-_29624343 0.237 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr5_+_75699040 0.236 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr14_-_106830057 0.225 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr6_+_109169591 0.222 ENST00000368972.3
ENST00000392644.4
ARMC2

armadillo repeat containing 2

chr7_-_37488834 0.217 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr6_-_39290316 0.215 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16



potassium channel, subfamily K, member 16



chr14_-_106963409 0.211 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr17_-_29641104 0.197 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr3_-_149095652 0.194 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr10_-_101841588 0.192 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr17_+_53342311 0.190 ENST00000226067.5
HLF
hepatic leukemia factor
chr12_+_123717967 0.180 ENST00000536130.1
ENST00000546132.1
C12orf65

chromosome 12 open reading frame 65

chr17_-_55911970 0.179 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3

RP11-60A24.3

chr7_+_142919130 0.179 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr5_+_78407602 0.177 ENST00000274353.5
ENST00000524080.1
BHMT

betaine--homocysteine S-methyltransferase

chr16_+_31483451 0.176 ENST00000565360.1
ENST00000361773.3
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr9_+_116263778 0.169 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr1_-_113498943 0.167 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr16_+_8814563 0.164 ENST00000425191.2
ENST00000569156.1
ABAT

4-aminobutyrate aminotransferase

chr7_-_94953878 0.161 ENST00000222381.3
PON1
paraoxonase 1
chr17_+_40811283 0.161 ENST00000251412.7
TUBG2
tubulin, gamma 2
chr17_-_19771216 0.159 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr18_-_13915530 0.156 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr17_-_10452929 0.155 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2


myosin, heavy chain 2, skeletal muscle, adult


chr17_+_29421987 0.154 ENST00000431387.4
NF1
neurofibromin 1
chr1_+_154300217 0.151 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr3_+_45984947 0.150 ENST00000304552.4
CXCR6
chemokine (C-X-C motif) receptor 6
chr14_+_23654525 0.147 ENST00000399910.1
ENST00000492621.1
C14orf164

chromosome 14 open reading frame 164

chr1_-_160616804 0.146 ENST00000538290.1
SLAMF1
signaling lymphocytic activation molecule family member 1
chr18_+_42260861 0.143 ENST00000282030.5
SETBP1
SET binding protein 1
chr16_+_3194211 0.140 ENST00000428155.1
CASP16
caspase 16, apoptosis-related cysteine peptidase (putative)
chr17_-_79623597 0.139 ENST00000574024.1
ENST00000331056.5
PDE6G

phosphodiesterase 6G, cGMP-specific, rod, gamma

chr20_-_41818373 0.134 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT



protein tyrosine phosphatase, receptor type, T



chr12_+_123717458 0.133 ENST00000253233.1
C12orf65
chromosome 12 open reading frame 65
chr3_+_124223586 0.131 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr8_-_120651020 0.131 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr22_+_40322623 0.130 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr22_+_40322595 0.130 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr15_+_78799948 0.127 ENST00000566332.1
HYKK
hydroxylysine kinase
chr2_+_152214098 0.126 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_-_87342564 0.124 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr7_-_81399329 0.124 ENST00000453411.1
ENST00000444829.2
HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

chr9_+_116263639 0.122 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr16_-_30134524 0.122 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr6_-_94129244 0.122 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr14_+_22356029 0.121 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr8_+_133879193 0.118 ENST00000377869.1
ENST00000220616.4
TG

thyroglobulin

chr3_-_47950745 0.117 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr12_+_4918342 0.117 ENST00000280684.3
ENST00000433855.1
KCNA6

potassium voltage-gated channel, shaker-related subfamily, member 6

chr2_-_187713891 0.117 ENST00000295131.2
ZSWIM2
zinc finger, SWIM-type containing 2
chr10_+_75504105 0.116 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C





SEC24 family member C





chr1_-_23520755 0.115 ENST00000314113.3
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr2_+_113403434 0.114 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr12_-_4553385 0.113 ENST00000543077.1
FGF6
fibroblast growth factor 6
chr1_+_159796534 0.113 ENST00000289707.5
SLAMF8
SLAM family member 8
chr1_-_160040038 0.111 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr15_+_78799895 0.110 ENST00000408962.2
ENST00000388988.4
ENST00000360519.3
HYKK


hydroxylysine kinase


chr20_-_271304 0.109 ENST00000400269.3
ENST00000360321.2
C20orf96

chromosome 20 open reading frame 96

chr18_+_61575200 0.109 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr7_+_142457315 0.108 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr12_-_123717643 0.107 ENST00000541437.1
ENST00000606320.1
MPHOSPH9

M-phase phosphoprotein 9

chr20_-_271009 0.106 ENST00000382369.5
C20orf96
chromosome 20 open reading frame 96
chr2_-_162931052 0.106 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chrX_-_30326445 0.106 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr19_+_5681011 0.106 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr1_+_166958346 0.105 ENST00000367872.4
MAEL
maelstrom spermatogenic transposon silencer
chr17_-_7493390 0.105 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15


SRY (sex determining region Y)-box 15


chr11_-_19223523 0.100 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr3_+_108321623 0.100 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr6_+_33378738 0.097 ENST00000374512.3
ENST00000374516.3
PHF1

PHD finger protein 1

chr1_-_102312517 0.097 ENST00000338858.5
OLFM3
olfactomedin 3
chr12_-_53097247 0.096 ENST00000341809.3
ENST00000537195.1
KRT77

keratin 77

chr15_+_81589254 0.096 ENST00000394652.2
IL16
interleukin 16
chr9_+_35906176 0.095 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr7_+_99775366 0.094 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr14_+_81421355 0.094 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr2_+_136289030 0.092 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1



R3H domain containing 1



chr17_-_56621665 0.091 ENST00000321691.3
C17orf47
chromosome 17 open reading frame 47
chrX_+_86772787 0.091 ENST00000373114.4
KLHL4
kelch-like family member 4
chr3_-_194072019 0.090 ENST00000429275.1
ENST00000323830.3
CPN2

carboxypeptidase N, polypeptide 2

chr12_-_371994 0.089 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13



solute carrier family 6 (neurotransmitter transporter), member 13



chr15_-_42840961 0.087 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57



leucine rich repeat containing 57



chr13_+_109248500 0.087 ENST00000356711.2
MYO16
myosin XVI
chrX_+_86772707 0.087 ENST00000373119.4
KLHL4
kelch-like family member 4
chr2_+_219646462 0.085 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr8_-_72459885 0.085 ENST00000523987.1
RP11-1102P16.1
Uncharacterized protein
chr16_-_30134266 0.084 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3

chr1_-_22109682 0.084 ENST00000400301.1
ENST00000532737.1
USP48

ubiquitin specific peptidase 48

chr10_+_73156664 0.083 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23



cadherin-related 23



chr14_+_81421710 0.083 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr7_+_99775520 0.082 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr11_-_116663127 0.082 ENST00000433069.1
ENST00000542499.1
APOA5

apolipoprotein A-V

chr21_+_17791838 0.081 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr10_-_128359074 0.081 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr14_+_81421861 0.079 ENST00000298171.2
TSHR
thyroid stimulating hormone receptor
chr14_+_81421921 0.079 ENST00000554263.1
ENST00000554435.1
TSHR

thyroid stimulating hormone receptor

chrX_-_154299501 0.079 ENST00000369484.3
ENST00000369476.3
CMC4
MTCP1
C-x(9)-C motif containing 4
mature T-cell proliferation 1
chr2_-_175499294 0.079 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr16_-_3149278 0.078 ENST00000575108.1
ENST00000576483.1
ENST00000538082.2
ENST00000576985.1
ZSCAN10



zinc finger and SCAN domain containing 10



chr4_+_144354644 0.077 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr6_-_134373732 0.076 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr20_+_55841819 0.075 ENST00000412321.1
ENST00000426580.1
RP4-813D12.3

RP4-813D12.3

chr17_-_13505219 0.074 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr1_+_26606608 0.070 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr17_-_3500392 0.068 ENST00000571088.1
ENST00000174621.6
TRPV1

transient receptor potential cation channel, subfamily V, member 1

chr13_-_53422640 0.066 ENST00000338862.4
ENST00000377942.3
PCDH8

protocadherin 8

chr17_+_54230819 0.065 ENST00000318698.2
ENST00000566473.2
ANKFN1

ankyrin-repeat and fibronectin type III domain containing 1

chr8_+_48873453 0.065 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr1_+_32671236 0.065 ENST00000537469.1
ENST00000291358.6
IQCC

IQ motif containing C

chr21_+_17791648 0.065 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478


long intergenic non-protein coding RNA 478


chr8_+_87878640 0.063 ENST00000518476.1
CNBD1
cyclic nucleotide binding domain containing 1
chr2_-_85895295 0.062 ENST00000428225.1
ENST00000519937.2
SFTPB

surfactant protein B

chr2_+_48541776 0.062 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr13_-_95364389 0.060 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr8_+_48873479 0.059 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr3_-_123710893 0.059 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1







rhophilin associated tail protein 1







chr7_-_28220354 0.058 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr7_+_130020180 0.055 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
CPA1


carboxypeptidase A1 (pancreatic)


chr5_-_74062930 0.054 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2



G elongation factor, mitochondrial 2



chr3_+_125687987 0.054 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B




rhophilin associated tail protein 1B




chr5_+_147258266 0.053 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr22_-_29137771 0.052 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2









checkpoint kinase 2









chrX_+_14547632 0.052 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chr11_+_60102304 0.050 ENST00000300182.4
MS4A6E
membrane-spanning 4-domains, subfamily A, member 6E
chr17_+_26646121 0.050 ENST00000226230.6
TMEM97
transmembrane protein 97
chr4_-_74853897 0.048 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr5_-_76788317 0.046 ENST00000296679.4
WDR41
WD repeat domain 41
chr19_-_5680499 0.046 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chrX_-_142722897 0.045 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr8_-_10588010 0.045 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr19_-_5680891 0.045 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr3_-_15374659 0.044 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr1_-_149982624 0.043 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr3_+_125694347 0.043 ENST00000505382.1
ENST00000511082.1
ROPN1B

rhophilin associated tail protein 1B

chr17_+_58755184 0.043 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr7_-_44229022 0.043 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr1_+_161676983 0.040 ENST00000367957.2
FCRLA
Fc receptor-like A
chr15_-_74726283 0.038 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr8_+_9009296 0.038 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr16_-_57809015 0.038 ENST00000540079.2
ENST00000569222.1
KIFC3

kinesin family member C3

chr15_+_42841008 0.037 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2



HAUS augmin-like complex, subunit 2



chr17_+_38333263 0.037 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chrX_-_49041242 0.036 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3



prickle homolog 3 (Drosophila)



chr11_+_64879317 0.036 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2










transmembrane 7 superfamily member 2










chr15_-_81282133 0.036 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chrY_+_16634483 0.036 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chrX_+_71353499 0.035 ENST00000373677.1
NHSL2
NHS-like 2
chr1_+_161676739 0.035 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA






Fc receptor-like A






chr9_-_34048873 0.035 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr7_-_99774945 0.033 ENST00000292377.2
GPC2
glypican 2
chr17_-_46667594 0.032 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3


homeobox B3


chr1_+_161677034 0.032 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA




Fc receptor-like A




chr9_+_33265011 0.031 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr10_-_99531709 0.031 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr2_+_201997492 0.030 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr6_-_112115074 0.028 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr1_-_207143802 0.028 ENST00000324852.4
ENST00000400962.3
FCAMR

Fc receptor, IgA, IgM, high affinity

chr3_+_46283863 0.027 ENST00000545097.1
ENST00000541018.1
CCR3

chemokine (C-C motif) receptor 3

chr11_-_118436707 0.026 ENST00000264020.2
ENST00000264021.3
IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chrX_-_49965663 0.026 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4


A kinase (PRKA) anchor protein 4


chr2_+_201936458 0.026 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr9_+_33264861 0.025 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr14_+_94393605 0.025 ENST00000556222.1
ENST00000554404.1
ENST00000557000.2
FAM181A


family with sequence similarity 181, member A


chr3_-_113415441 0.025 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr3_+_46283916 0.024 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr3_-_56717246 0.024 ENST00000355628.5
FAM208A
family with sequence similarity 208, member A
chr6_-_41715128 0.023 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC


progastricsin (pepsinogen C)


chr1_-_102462565 0.022 ENST00000370103.4
OLFM3
olfactomedin 3
chr10_+_133753533 0.022 ENST00000422256.2
PPP2R2D
protein phosphatase 2, regulatory subunit B, delta
chr6_-_27279949 0.022 ENST00000444565.1
ENST00000377451.2
POM121L2

POM121 transmembrane nucleoporin-like 2

chr11_-_118436606 0.019 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr1_-_11907829 0.019 ENST00000376480.3
NPPA
natriuretic peptide A
chr7_-_27224795 0.019 ENST00000006015.3
HOXA11
homeobox A11
chr12_+_56360550 0.019 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr5_-_171615315 0.019 ENST00000176763.5
STK10
serine/threonine kinase 10
chr16_+_33006369 0.018 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr5_+_74062806 0.018 ENST00000296802.5
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr17_+_46048376 0.017 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr7_-_81399438 0.016 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_+_113354341 0.015 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_27153173 0.015 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr7_+_129906660 0.014 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr7_-_150675372 0.013 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_-_18813110 0.013 ENST00000396168.1
PTPN5
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr7_-_27224842 0.013 ENST00000517402.1
HOXA11
homeobox A11
chr17_-_46667628 0.012 ENST00000498678.1
HOXB3
homeobox B3
chr11_+_108093839 0.012 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr1_-_115259337 0.012 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.2 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.2 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.2 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.2 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 0.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.2 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0035473 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters