Motif ID: NFIA
Z-value: 0.936

Transcription factors associated with NFIA:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
NFIA | ENSG00000162599.11 | NFIA |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
NFIA | hg19_v2_chr1_+_61869748_61869782 | -0.63 | 9.8e-04 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 206 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.9 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
0.1 | 4.7 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
1.5 | 4.6 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
1.1 | 4.2 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.2 | 4.0 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.1 | 2.9 | GO:0051602 | response to electrical stimulus(GO:0051602) |
0.0 | 2.9 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
0.6 | 2.5 | GO:0090119 | vesicle-mediated cholesterol transport(GO:0090119) |
0.3 | 2.4 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
0.2 | 2.4 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
0.2 | 2.4 | GO:1902172 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
0.3 | 2.2 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.7 | 2.1 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
0.4 | 2.0 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
0.0 | 1.9 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
0.6 | 1.8 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.3 | 1.8 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
0.0 | 1.8 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
0.3 | 1.7 | GO:2000391 | positive regulation of neutrophil extravasation(GO:2000391) |
0.0 | 1.7 | GO:0060612 | adipose tissue development(GO:0060612) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 72 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.4 | GO:0001533 | cornified envelope(GO:0001533) |
1.5 | 4.6 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
0.0 | 3.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.1 | 2.8 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 2.5 | GO:0002102 | podosome(GO:0002102) |
0.0 | 2.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.1 | 2.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.3 | 2.2 | GO:0035976 | AP1 complex(GO:0035976) |
0.0 | 2.1 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 2.1 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.2 | 2.0 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.1 | 2.0 | GO:0033643 | host cell part(GO:0033643) |
0.0 | 1.5 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 1.4 | GO:0072686 | mitotic spindle(GO:0072686) |
0.3 | 1.2 | GO:0036156 | inner dynein arm(GO:0036156) |
0.0 | 1.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.3 | 1.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 1.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.0 | 1.0 | GO:0031430 | M band(GO:0031430) |
0.0 | 0.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 138 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.5 | 4.2 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
0.0 | 3.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 3.3 | GO:0044325 | ion channel binding(GO:0044325) |
0.5 | 2.5 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
0.1 | 2.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 2.2 | GO:0005179 | hormone activity(GO:0005179) |
0.2 | 2.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.0 | 2.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 2.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.4 | 2.0 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
0.1 | 2.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.1 | 2.0 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
0.4 | 1.8 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
0.3 | 1.8 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
0.1 | 1.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.4 | 1.6 | GO:0030305 | heparanase activity(GO:0030305) |
0.1 | 1.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.3 | 1.3 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.0 | 1.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 27 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.1 | 3.9 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 3.6 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 2.4 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 2.3 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.1 | 2.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 2.0 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 1.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.8 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 1.7 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 1.5 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 1.4 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 1.3 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 1.2 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.9 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 0.8 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.6 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.6 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.1 | 0.5 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.5 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 39 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 5.8 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.3 | 4.2 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.1 | 2.8 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 2.4 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.2 | 2.2 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
0.0 | 2.2 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 1.9 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.1 | 1.8 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.1 | 1.7 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.1 | 1.6 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 1.4 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 1.3 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 1.3 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.9 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
0.0 | 0.8 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.7 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.0 | 0.7 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.0 | 0.7 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |