Motif ID: MYF6

Z-value: 0.937


Transcription factors associated with MYF6:

Gene SymbolEntrez IDGene Name
MYF6 ENSG00000111046.3 MYF6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYF6hg19_v2_chr12_+_81101277_811013210.377.9e-02Click!


Activity profile for motif MYF6.

activity profile for motif MYF6


Sorted Z-values histogram for motif MYF6

Sorted Z-values for motif MYF6



Network of associatons between targets according to the STRING database.



First level regulatory network of MYF6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39274606 2.660 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr17_-_39306054 2.102 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5
chr19_-_51504411 1.967 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr17_-_39324424 1.933 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chrX_-_38080077 1.742 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX



sushi-repeat containing protein, X-linked



chr20_-_52790512 1.418 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr20_-_52790055 1.383 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr3_-_124774802 1.232 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr19_-_51504852 1.141 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
KLK8



kallikrein-related peptidase 8



chr12_-_76425368 1.045 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr7_+_145813453 0.856 ENST00000361727.3
CNTNAP2
contactin associated protein-like 2
chr2_-_216300784 0.828 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr13_-_36050819 0.822 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr4_+_7194247 0.796 ENST00000507866.2
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr5_-_44388899 0.777 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr14_-_75422280 0.742 ENST00000238607.6
ENST00000553716.1
PGF

placental growth factor

chr19_+_54371114 0.725 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM



myeloid-associated differentiation marker



chr1_+_20915409 0.642 ENST00000375071.3
CDA
cytidine deaminase
chr22_+_31489344 0.641 ENST00000404574.1
SMTN
smoothelin
chr2_+_115199876 0.635 ENST00000436732.1
ENST00000410059.1
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr9_+_116298778 0.633 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr11_-_65325664 0.620 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chr5_-_147162078 0.584 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr7_-_128045984 0.576 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr19_+_35521616 0.572 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr22_+_38071615 0.562 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr19_-_38397285 0.557 ENST00000303868.5
WDR87
WD repeat domain 87
chr20_+_33759854 0.557 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr8_-_82024290 0.547 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr8_+_31497271 0.547 ENST00000520407.1
NRG1
neuregulin 1
chr12_-_125348329 0.544 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1




scavenger receptor class B, member 1




chr5_-_72744336 0.538 ENST00000499003.3
FOXD1
forkhead box D1
chr5_-_146258291 0.520 ENST00000394411.4
ENST00000453001.1
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr17_-_39507064 0.515 ENST00000007735.3
KRT33A
keratin 33A
chr21_+_37507210 0.514 ENST00000290354.5
CBR3
carbonyl reductase 3
chr9_-_35685452 0.503 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr11_-_1643368 0.502 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr2_-_31360887 0.495 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)


chr14_+_73706308 0.491 ENST00000554301.1
ENST00000555445.1
PAPLN

papilin, proteoglycan-like sulfated glycoprotein

chr6_-_30654977 0.489 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr5_-_147162263 0.484 ENST00000333010.6
ENST00000265272.5
JAKMIP2

janus kinase and microtubule interacting protein 2

chr2_-_220408430 0.481 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr12_-_122241812 0.477 ENST00000538335.1
AC084018.1
AC084018.1
chr9_+_132815985 0.472 ENST00000372410.3
GPR107
G protein-coupled receptor 107
chr15_+_90744533 0.468 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr17_-_39211463 0.468 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr8_-_23712312 0.465 ENST00000290271.2
STC1
stanniocalcin 1
chr20_-_60942361 0.460 ENST00000252999.3
LAMA5
laminin, alpha 5
chr11_-_65325430 0.459 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr12_-_95044309 0.456 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr22_+_30792846 0.454 ENST00000312932.9
ENST00000428195.1
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr17_-_39183452 0.449 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr17_-_39538550 0.448 ENST00000394001.1
KRT34
keratin 34
chr16_+_335680 0.446 ENST00000435833.1
PDIA2
protein disulfide isomerase family A, member 2
chr21_+_10862622 0.446 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1

immunoglobulin heavy variable 1/OR21-1 (non-functional)

chr13_-_114567034 0.445 ENST00000327773.6
ENST00000357389.3
GAS6

growth arrest-specific 6

chr1_+_55505184 0.442 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr20_+_2795626 0.442 ENST00000603872.1
ENST00000380589.4
C20orf141

chromosome 20 open reading frame 141

chrX_+_68725084 0.435 ENST00000252338.4
FAM155B
family with sequence similarity 155, member B
chr17_+_39261584 0.428 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr2_+_148778570 0.421 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr12_-_54813229 0.420 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_52860850 0.420 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr15_-_63674034 0.417 ENST00000344366.3
ENST00000422263.2
CA12

carbonic anhydrase XII

chr4_-_56502426 0.416 ENST00000505262.1
ENST00000507338.1
NMU

neuromedin U

chrX_-_107018969 0.414 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr16_-_2770216 0.413 ENST00000302641.3
PRSS27
protease, serine 27
chr2_-_235405168 0.412 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr16_+_2867228 0.410 ENST00000005995.3
ENST00000574813.1
PRSS21

protease, serine, 21 (testisin)

chr21_+_30502806 0.405 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr1_+_32687971 0.403 ENST00000373586.1
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr11_-_62323702 0.400 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr19_+_39687596 0.392 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chrX_-_106959631 0.388 ENST00000486554.1
ENST00000372390.4
TSC22D3

TSC22 domain family, member 3

chr19_-_51014460 0.383 ENST00000595669.1
JOSD2
Josephin domain containing 2
chr11_-_66725837 0.379 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr6_+_42896865 0.376 ENST00000372836.4
ENST00000394142.3
CNPY3

canopy FGF signaling regulator 3

chr10_-_48438974 0.376 ENST00000224605.2
GDF10
growth differentiation factor 10
chr11_-_10829851 0.375 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr9_+_35673853 0.375 ENST00000378357.4
CA9
carbonic anhydrase IX
chr16_-_74640986 0.373 ENST00000422840.2
ENST00000565260.1
ENST00000447066.2
ENST00000205061.5
GLG1



golgi glycoprotein 1



chr16_+_30064444 0.373 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA


aldolase A, fructose-bisphosphate


chr19_+_6531010 0.371 ENST00000245817.3
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chrX_-_110513703 0.371 ENST00000324068.1
CAPN6
calpain 6
chr10_-_133109947 0.368 ENST00000368642.4
TCERG1L
transcription elongation regulator 1-like
chr10_+_99473455 0.364 ENST00000285605.6
MARVELD1
MARVEL domain containing 1
chr7_+_2687173 0.363 ENST00000403167.1
TTYH3
tweety family member 3
chr19_+_48216600 0.363 ENST00000263277.3
ENST00000538399.1
EHD2

EH-domain containing 2

chr4_+_102268904 0.362 ENST00000527564.1
ENST00000529296.1
AP001816.1

Uncharacterized protein

chr11_-_65325203 0.362 ENST00000526927.1
ENST00000536982.1
LTBP3

latent transforming growth factor beta binding protein 3

chr6_+_45390222 0.362 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr12_-_125348448 0.359 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr4_-_56502451 0.358 ENST00000511469.1
ENST00000264218.3
NMU

neuromedin U

chr17_+_39411636 0.357 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr7_+_5111723 0.356 ENST00000498308.1
RBAKDN
RBAK downstream neighbor (non-protein coding)
chrX_-_128788914 0.354 ENST00000429967.1
ENST00000307484.6
APLN

apelin

chr17_-_26903900 0.350 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chr11_-_9113137 0.346 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2


signal peptide, CUB domain, EGF-like 2


chr17_-_39526052 0.343 ENST00000251646.3
KRT33B
keratin 33B
chr15_-_74501360 0.338 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chrX_+_86772787 0.337 ENST00000373114.4
KLHL4
kelch-like family member 4
chr6_-_137365402 0.336 ENST00000541547.1
IL20RA
interleukin 20 receptor, alpha
chr1_-_154842741 0.336 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr14_+_72399114 0.336 ENST00000553525.1
ENST00000555571.1
RGS6

regulator of G-protein signaling 6

chr17_-_39254391 0.335 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr1_+_213123976 0.332 ENST00000366965.2
ENST00000366967.2
VASH2

vasohibin 2

chr8_-_144651024 0.331 ENST00000524906.1
ENST00000532862.1
ENST00000534459.1
MROH6


maestro heat-like repeat family member 6


chr3_+_167453493 0.328 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr17_-_39553844 0.327 ENST00000251645.2
KRT31
keratin 31
chr22_+_48027423 0.326 ENST00000423737.1
RP11-191L9.4
RP11-191L9.4
chr19_-_49220084 0.323 ENST00000595591.1
ENST00000356751.4
ENST00000594582.1
MAMSTR


MEF2 activating motif and SAP domain containing transcriptional regulator


chr7_-_137028498 0.317 ENST00000393083.2
PTN
pleiotrophin
chr17_+_1959369 0.316 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr22_-_19137796 0.314 ENST00000086933.2
GSC2
goosecoid homeobox 2
chr22_+_30792980 0.313 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr11_-_9113093 0.311 ENST00000450649.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr3_+_110790590 0.310 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr19_-_19051103 0.309 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr3_-_87040233 0.307 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr19_-_14048804 0.305 ENST00000254320.3
ENST00000586075.1
PODNL1

podocan-like 1

chr7_-_100860851 0.302 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr17_-_3417062 0.300 ENST00000570318.1
ENST00000541913.1
SPATA22

spermatogenesis associated 22

chr12_+_26274917 0.297 ENST00000538142.1
SSPN
sarcospan
chr22_-_50964558 0.296 ENST00000535425.1
ENST00000439934.1
SCO2

SCO2 cytochrome c oxidase assembly protein

chr3_+_140770183 0.296 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_+_213123915 0.296 ENST00000366968.4
ENST00000490792.1
VASH2

vasohibin 2

chr16_+_6533380 0.295 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_-_57582296 0.294 ENST00000217131.5
CTSZ
cathepsin Z
chr10_-_79397740 0.294 ENST00000372440.1
ENST00000480683.1
KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

chr3_-_58196939 0.294 ENST00000394549.2
ENST00000461914.3
DNASE1L3

deoxyribonuclease I-like 3

chr20_-_14318248 0.293 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr6_-_32122106 0.290 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr1_+_200842083 0.290 ENST00000304244.2
GPR25
G protein-coupled receptor 25
chr15_-_63674218 0.290 ENST00000178638.3
CA12
carbonic anhydrase XII
chr19_+_54926621 0.289 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1



tweety family member 1



chr19_-_46526304 0.288 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr17_-_39743139 0.285 ENST00000167586.6
KRT14
keratin 14
chrX_+_73641286 0.283 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr11_-_30038490 0.281 ENST00000328224.6
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr9_+_125133315 0.281 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr17_-_39203519 0.280 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr19_-_44174330 0.278 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr7_-_137028534 0.278 ENST00000348225.2
PTN
pleiotrophin
chr2_+_105471969 0.277 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr11_-_67120974 0.277 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr18_+_56530794 0.276 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532


zinc finger protein 532


chr2_+_239008780 0.274 ENST00000343063.3
ESPNL
espin-like
chr11_+_45944190 0.272 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B



glycosyltransferase-like 1B



chr14_+_29236269 0.272 ENST00000313071.4
FOXG1
forkhead box G1
chr1_+_150245099 0.271 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr16_+_30064411 0.270 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr19_+_54926601 0.270 ENST00000301194.4
TTYH1
tweety family member 1
chrX_-_151619746 0.270 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr17_+_7905912 0.268 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr16_+_2867164 0.268 ENST00000455114.1
ENST00000450020.3
PRSS21

protease, serine, 21 (testisin)

chr8_+_104383728 0.265 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr8_+_145162629 0.264 ENST00000323662.8
KIAA1875
KIAA1875
chr2_+_239009020 0.263 ENST00000409169.1
ESPNL
espin-like
chr17_-_39216344 0.262 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr17_-_39296739 0.262 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr20_+_1246908 0.261 ENST00000381873.3
ENST00000381867.1
SNPH

syntaphilin

chr1_+_10509971 0.260 ENST00000320498.4
CORT
cortistatin
chr6_+_129204337 0.259 ENST00000421865.2
LAMA2
laminin, alpha 2
chr19_+_41103063 0.256 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr7_+_96635277 0.255 ENST00000007660.5
DLX6
distal-less homeobox 6
chr16_+_333152 0.255 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2


protein disulfide isomerase family A, member 2


chr12_+_56521840 0.252 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr19_-_44174305 0.251 ENST00000601723.1
ENST00000339082.3
PLAUR

plasminogen activator, urokinase receptor

chr14_+_100150622 0.251 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr11_-_119187826 0.249 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr17_+_40274756 0.249 ENST00000355067.3
HSPB9
heat shock protein, alpha-crystallin-related, B9
chr3_-_145878954 0.248 ENST00000282903.5
ENST00000360060.3
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr16_+_56623433 0.248 ENST00000570176.1
MT3
metallothionein 3
chr11_-_14913190 0.246 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chrX_+_21392553 0.246 ENST00000279451.4
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr2_+_185463093 0.246 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr17_+_74381343 0.245 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr19_+_54385439 0.244 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
PRKCG



protein kinase C, gamma



chr3_+_156009623 0.243 ENST00000389634.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr19_-_51014588 0.243 ENST00000598418.1
JOSD2
Josephin domain containing 2
chr1_+_153004800 0.242 ENST00000392661.3
SPRR1B
small proline-rich protein 1B
chr11_+_369804 0.242 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr2_+_37571717 0.242 ENST00000338415.3
ENST00000404976.1
QPCT

glutaminyl-peptide cyclotransferase

chr10_-_90967063 0.242 ENST00000371852.2
CH25H
cholesterol 25-hydroxylase
chr8_-_68658578 0.241 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6


carboxypeptidase A6


chr3_+_124303539 0.241 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr19_-_40324767 0.240 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B



dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B



chr19_-_14049184 0.240 ENST00000339560.5
PODNL1
podocan-like 1
chr20_+_23420885 0.238 ENST00000246020.2
CSTL1
cystatin-like 1
chr19_-_49222956 0.238 ENST00000599703.1
ENST00000318083.6
ENST00000419611.1
ENST00000377367.3
MAMSTR



MEF2 activating motif and SAP domain containing transcriptional regulator



chr2_-_110371720 0.237 ENST00000356688.4
SEPT10
septin 10
chr12_-_2027639 0.237 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4


calcium channel, voltage-dependent, alpha 2/delta subunit 4


chr14_-_75330537 0.237 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2


prospero homeobox 2


chr4_-_52904425 0.236 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr12_+_9144626 0.235 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr9_-_131940526 0.234 ENST00000372491.2
IER5L
immediate early response 5-like
chr17_-_80009650 0.234 ENST00000310496.4
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_-_137514617 0.233 ENST00000254900.5
BRD8
bromodomain containing 8
chr1_-_236228403 0.233 ENST00000366595.3
NID1
nidogen 1
chr16_+_70680439 0.233 ENST00000288098.2
IL34
interleukin 34

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.4 1.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 3.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.4 1.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 1.0 GO:0045210 FasL biosynthetic process(GO:0045210)
0.3 0.9 GO:0060435 bronchiole development(GO:0060435)
0.3 0.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 0.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.3 0.8 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.4 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 0.7 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.2 0.6 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 1.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.6 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.5 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.4 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.5 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.4 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.4 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.3 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.5 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.2 GO:0055073 cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.1 0.7 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 1.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:0070235 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of activation-induced cell death of T cells(GO:0070235) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.2 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.6 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.2 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.3 GO:0072233 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.1 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 10.7 GO:0031424 keratinization(GO:0031424)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.2 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.0 GO:0021539 subthalamus development(GO:0021539)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880) regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.2 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.8 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.6 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.1 GO:0042116 macrophage activation(GO:0042116)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0050779 RNA destabilization(GO:0050779)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0003229 ventricular cardiac muscle tissue development(GO:0003229)
0.0 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.0 GO:0002339 positive regulation of type I hypersensitivity(GO:0001812) B cell selection(GO:0002339)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.0 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0006408 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.0 GO:0007181 ventricular compact myocardium morphogenesis(GO:0003223) transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:2000553 positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.0 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:2000738 positive regulation of stem cell differentiation(GO:2000738)
0.0 0.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990667 PCSK9-LDLR complex(GO:1990666) PCSK9-AnxA2 complex(GO:1990667)
0.1 0.5 GO:0043259 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 8.1 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.3 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.2 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.3 GO:0005694 chromosome(GO:0005694)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0043005 neuron projection(GO:0043005)
0.0 2.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 1.9 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.0 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.3 0.9 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 0.4 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 0.8 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 0.5 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.6 GO:0030395 lactose binding(GO:0030395)
0.1 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 1.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0034481 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.0 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 4.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.7 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 1.1 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation