Motif ID: MNT_HEY1_HEY2

Z-value: 0.596

Transcription factors associated with MNT_HEY1_HEY2:

Gene SymbolEntrez IDGene Name
HEY1 ENSG00000164683.12 HEY1
HEY2 ENSG00000135547.4 HEY2
MNT ENSG00000070444.10 MNT

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MNThg19_v2_chr17_-_2304365_2304412-0.546.8e-03Click!
HEY1hg19_v2_chr8_-_80680078_806801010.331.2e-01Click!
HEY2hg19_v2_chr6_+_126070726_1260707680.262.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MNT_HEY1_HEY2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_17354617 1.260 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_17354587 1.112 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr9_-_124976185 0.948 ENST00000464484.2
LHX6
LIM homeobox 6
chr9_-_124976154 0.886 ENST00000482062.1
LHX6
LIM homeobox 6
chr13_+_35516390 0.864 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA


neurobeachin


chr6_+_73331918 0.837 ENST00000402622.2
ENST00000355635.3
ENST00000403813.2
ENST00000414165.2
KCNQ5



potassium voltage-gated channel, KQT-like subfamily, member 5



chr1_-_109656439 0.801 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr17_-_17109579 0.781 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr3_-_19988462 0.750 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr12_-_58146128 0.724 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4


cyclin-dependent kinase 4


chr8_-_110656995 0.704 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr6_-_39197226 0.677 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr1_-_42921915 0.636 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr12_-_58146048 0.636 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4




cyclin-dependent kinase 4




chr3_-_71834318 0.612 ENST00000353065.3
PROK2
prokineticin 2
chr1_+_150254936 0.607 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr11_+_65479702 0.595 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr15_+_45315302 0.594 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr8_+_75896731 0.589 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr3_+_113666748 0.587 ENST00000330212.3
ENST00000498275.1
ZDHHC23

zinc finger, DHHC-type containing 23

chr15_+_82555125 0.580 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chrX_+_152240819 0.573 ENST00000535416.1
ENST00000421798.3
PNMA6A
PNMA6C
paraneoplastic Ma antigen family member 6A
paraneoplastic Ma antigen family member 6C
chr19_+_5720666 0.565 ENST00000381624.3
ENST00000381614.2
CATSPERD

catsper channel auxiliary subunit delta

chr2_-_220108309 0.563 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr12_+_50355647 0.562 ENST00000293599.6
AQP5
aquaporin 5
chr6_+_31865552 0.560 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr16_+_84178874 0.542 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chrX_+_152338301 0.540 ENST00000453825.2
PNMA6A
paraneoplastic Ma antigen family member 6A
chr17_+_72270380 0.532 ENST00000582036.1
ENST00000307504.5
DNAI2

dynein, axonemal, intermediate chain 2

chr17_-_42907564 0.532 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chrX_-_34675391 0.532 ENST00000275954.3
TMEM47
transmembrane protein 47
chr19_-_55672037 0.523 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr20_-_21494654 0.521 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr3_-_122512619 0.497 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr17_+_72270429 0.485 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr16_+_333152 0.485 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2


protein disulfide isomerase family A, member 2


chr22_-_31741757 0.480 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_109656579 0.475 ENST00000526264.1
ENST00000369939.3
KIAA1324

KIAA1324

chr19_-_11545920 0.472 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chr20_-_2821271 0.466 ENST00000448755.1
ENST00000360652.2
PCED1A

PC-esterase domain containing 1A

chr17_-_39203519 0.463 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr20_+_44657845 0.453 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr14_-_20923195 0.453 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr3_-_45883558 0.436 ENST00000445698.1
ENST00000296135.6
LZTFL1

leucine zipper transcription factor-like 1

chr7_+_142829162 0.435 ENST00000291009.3
PIP
prolactin-induced protein
chr11_+_125774362 0.428 ENST00000530414.1
ENST00000530129.2
DDX25

DEAD (Asp-Glu-Ala-Asp) box helicase 25

chr17_+_40440481 0.427 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr2_+_27805880 0.421 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512



zinc finger protein 512



chr12_-_112450915 0.419 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
TMEM116





transmembrane protein 116





chrX_+_24711997 0.419 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr16_+_29467127 0.418 ENST00000344620.6
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr5_-_133706695 0.415 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3





cyclin-dependent kinase-like 3





chr8_-_110703819 0.411 ENST00000532779.1
ENST00000534578.1
SYBU

syntabulin (syntaxin-interacting)

chr8_-_110704014 0.409 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU


syntabulin (syntaxin-interacting)


chr2_-_68384603 0.407 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92


WD repeat domain 92


chr22_-_36903101 0.405 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr1_+_154193325 0.399 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L





ubiquitin associated protein 2-like





chr11_+_125774258 0.395 ENST00000263576.6
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr9_+_117373486 0.395 ENST00000288502.4
ENST00000374049.4
C9orf91

chromosome 9 open reading frame 91

chr15_-_83316254 0.395 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr8_-_75233563 0.393 ENST00000342232.4
JPH1
junctophilin 1
chr7_-_150675372 0.392 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_122526499 0.389 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr4_+_129732467 0.383 ENST00000413543.2
PHF17
jade family PHD finger 1
chr3_+_63638339 0.378 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr5_-_1112141 0.375 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr15_+_27112948 0.371 ENST00000555060.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr2_+_172864490 0.371 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr10_-_6019552 0.370 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA


interleukin 15 receptor, alpha


chr7_+_97361218 0.363 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr11_+_126081662 0.362 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
FAM118B



family with sequence similarity 118, member B



chr17_-_6915646 0.360 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2




Uncharacterized protein




chr22_+_29279552 0.357 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chrX_+_55744166 0.357 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr2_+_46926326 0.356 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr7_+_26191809 0.356 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr11_+_67776012 0.355 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr6_-_90121789 0.353 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr1_-_207119738 0.351 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr4_+_72052964 0.351 ENST00000264485.5
ENST00000425175.1
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr16_+_67282853 0.351 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr22_-_42765174 0.351 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1


Z83851.1


chr2_-_160143158 0.350 ENST00000409124.1
ENST00000358147.4
WDSUB1

WD repeat, sterile alpha motif and U-box domain containing 1

chrX_+_55744228 0.349 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr17_+_48172639 0.347 ENST00000503176.1
ENST00000503614.1
PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr19_-_10764509 0.346 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr2_-_160143242 0.345 ENST00000359774.4
WDSUB1
WD repeat, sterile alpha motif and U-box domain containing 1
chrX_+_128913906 0.343 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr1_-_212873267 0.341 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr2_-_160143059 0.341 ENST00000392796.3
WDSUB1
WD repeat, sterile alpha motif and U-box domain containing 1
chr3_-_42306248 0.341 ENST00000334681.5
CCK
cholecystokinin
chr1_-_111746966 0.338 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr7_+_97361388 0.338 ENST00000350485.4
ENST00000346867.4
TAC1

tachykinin, precursor 1

chr4_+_76439665 0.337 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6







THAP domain containing 6







chr12_-_49318715 0.336 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr19_+_50180317 0.336 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr2_-_160143084 0.335 ENST00000409990.3
WDSUB1
WD repeat, sterile alpha motif and U-box domain containing 1
chr10_+_49514698 0.334 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8


mitogen-activated protein kinase 8


chr21_-_46330545 0.332 ENST00000320216.6
ENST00000397852.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr7_+_116593568 0.330 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr7_-_130598059 0.324 ENST00000432045.2
MIR29B1
microRNA 29a
chr18_+_43913919 0.322 ENST00000587853.1
RNF165
ring finger protein 165
chr7_+_6793740 0.320 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
RSPH10B2



radial spoke head 10 homolog B2 (Chlamydomonas)



chr18_+_32556892 0.314 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2



microtubule-associated protein, RP/EB family, member 2



chr14_-_39901618 0.312 ENST00000554932.1
ENST00000298097.7
FBXO33

F-box protein 33

chr11_-_9781068 0.311 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr21_+_42694732 0.309 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr1_+_20512568 0.309 ENST00000375099.3
UBXN10
UBX domain protein 10
chr16_+_335680 0.307 ENST00000435833.1
PDIA2
protein disulfide isomerase family A, member 2
chr17_+_72428218 0.306 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr5_+_133706865 0.306 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr11_-_61684962 0.304 ENST00000394836.2
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr16_+_66914264 0.303 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr11_+_65479462 0.302 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5


K(lysine) acetyltransferase 5


chr5_-_54529415 0.300 ENST00000282572.4
CCNO
cyclin O
chr17_+_68165657 0.299 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_66336060 0.299 ENST00000310325.5
CTSF
cathepsin F
chr14_-_67981916 0.295 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr7_+_94537542 0.293 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr1_+_32712815 0.292 ENST00000373582.3
FAM167B
family with sequence similarity 167, member B
chr15_+_44084503 0.291 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr17_+_1627834 0.291 ENST00000419248.1
ENST00000418841.1
WDR81

WD repeat domain 81

chr9_-_139922726 0.290 ENST00000265662.5
ENST00000371605.3
ABCA2

ATP-binding cassette, sub-family A (ABC1), member 2

chr1_+_150229554 0.290 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr12_-_104234966 0.287 ENST00000392876.3
NT5DC3
5'-nucleotidase domain containing 3
chr7_+_116593433 0.286 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr8_+_95907993 0.278 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr16_-_1031520 0.277 ENST00000568394.1
ENST00000565467.1
RP11-161M6.2

RP11-161M6.2

chr9_-_124990680 0.276 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr4_+_128651530 0.276 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr3_+_51741072 0.274 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr2_+_216176761 0.273 ENST00000540518.1
ENST00000435675.1
ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

chr7_+_1094921 0.272 ENST00000397095.1
GPR146
G protein-coupled receptor 146
chr14_-_67982146 0.271 ENST00000557779.1
ENST00000557006.1
TMEM229B

transmembrane protein 229B

chr7_+_94536898 0.270 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr1_+_61548374 0.270 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA


nuclear factor I/A


chr9_+_133884469 0.267 ENST00000361069.4
LAMC3
laminin, gamma 3
chr16_+_84002234 0.266 ENST00000305202.4
NECAB2
N-terminal EF-hand calcium binding protein 2
chr12_-_15374343 0.265 ENST00000256953.2
ENST00000546331.1
RERG

RAS-like, estrogen-regulated, growth inhibitor

chr8_+_67341239 0.264 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr5_-_178054105 0.263 ENST00000316308.4
CLK4
CDC-like kinase 4
chr2_+_68384976 0.263 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr7_+_102105370 0.259 ENST00000292616.5
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr14_-_23770683 0.259 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E




protein phosphatase 1, regulatory subunit 3E




chr2_-_211036051 0.258 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chrX_-_153523462 0.256 ENST00000361930.3
ENST00000369926.1
TEX28

testis expressed 28

chr11_+_120894781 0.255 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL


tubulin folding cofactor E-like


chr6_+_126070726 0.255 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr10_-_104474128 0.254 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr11_+_1244288 0.254 ENST00000529681.1
ENST00000447027.1
MUC5B

mucin 5B, oligomeric mucus/gel-forming

chr1_+_11333245 0.253 ENST00000376810.5
UBIAD1
UbiA prenyltransferase domain containing 1
chr17_+_72427477 0.251 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr11_+_7534999 0.251 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr11_+_6866883 0.251 ENST00000299454.4
ENST00000379831.2
OR10A5

olfactory receptor, family 10, subfamily A, member 5

chr2_+_46926048 0.250 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr17_+_76311791 0.250 ENST00000586321.1
AC061992.2
AC061992.2
chr1_-_109655377 0.249 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr5_+_122110691 0.249 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr17_-_42908155 0.249 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1


gap junction protein, gamma 1, 45kDa


chr9_+_71320557 0.247 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr2_+_98330009 0.247 ENST00000264972.5
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr1_-_110613276 0.245 ENST00000369792.4
ALX3
ALX homeobox 3
chr9_+_37079888 0.245 ENST00000429493.1
ENST00000593237.1
ENST00000588557.1
ENST00000430809.1
ENST00000592157.1
RP11-220I1.1




RP11-220I1.1




chr22_-_20850128 0.244 ENST00000328879.4
KLHL22
kelch-like family member 22
chr2_-_47572105 0.243 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4



chr17_-_30186328 0.241 ENST00000302362.6
COPRS
coordinator of PRMT5, differentiation stimulator
chr17_-_30185971 0.241 ENST00000378634.2
COPRS
coordinator of PRMT5, differentiation stimulator
chr14_+_96505659 0.241 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chr16_-_28634874 0.240 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr11_-_73694346 0.240 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr8_-_103425047 0.240 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr2_+_10183651 0.239 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr14_-_92572894 0.239 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3













ataxin 3













chr7_+_100464760 0.239 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr6_-_39282221 0.235 ENST00000453413.2
KCNK17
potassium channel, subfamily K, member 17
chr2_+_216176540 0.234 ENST00000236959.9
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_+_28256874 0.233 ENST00000541045.1
ENST00000536908.2
EFCAB5

EF-hand calcium binding domain 5

chr17_+_4613918 0.233 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2






arrestin, beta 2






chr6_-_83775489 0.231 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr17_-_28257080 0.229 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2




slingshot protein phosphatase 2




chr3_+_119187785 0.228 ENST00000295588.4
ENST00000476573.1
POGLUT1

protein O-glucosyltransferase 1

chr22_-_20850070 0.226 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
KLHL22





kelch-like family member 22





chr6_-_84937314 0.225 ENST00000257766.4
ENST00000403245.3
KIAA1009

KIAA1009

chr15_+_41913690 0.224 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr6_-_39282329 0.224 ENST00000373231.4
KCNK17
potassium channel, subfamily K, member 17
chr10_-_98480243 0.223 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr5_+_43602750 0.221 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr17_-_34890665 0.221 ENST00000586007.1
MYO19
myosin XIX
chr13_+_27998681 0.220 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr6_+_127588020 0.220 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146




ring finger protein 146




chr5_-_37839782 0.220 ENST00000326524.2
ENST00000515058.1
GDNF

glial cell derived neurotrophic factor

chr22_-_39268192 0.219 ENST00000216083.6
CBX6
chromobox homolog 6
chr15_+_44084040 0.218 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr2_-_97652290 0.217 ENST00000327896.3
FAM178B
family with sequence similarity 178, member B
chr7_-_103629963 0.217 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr6_-_91006627 0.217 ENST00000537989.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr20_-_61051026 0.217 ENST00000252997.2
GATA5
GATA binding protein 5
chr10_-_71169031 0.216 ENST00000373307.1
TACR2
tachykinin receptor 2
chr2_+_198365095 0.215 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr17_-_5015129 0.215 ENST00000575898.1
ENST00000416429.2
ZNF232

zinc finger protein 232


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.2 0.7 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.2 1.4 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 0.6 GO:0006059 hexitol metabolic process(GO:0006059)
0.2 0.8 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.6 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2 2.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 1.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 1.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 1.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.4 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 0.1 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.2 GO:1902161 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.2 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.3 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:1902869 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.1 GO:0000732 strand displacement(GO:0000732)
0.0 0.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0003249 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) protein ufmylation(GO:0071569)
0.0 0.2 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.4 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0090162 establishment of cell polarity(GO:0030010) establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.0 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0043132 NAD transport(GO:0043132)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.0 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.2 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.6 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.0 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0048858 cell projection morphogenesis(GO:0048858)
0.0 0.0 GO:0002337 B-1 B cell differentiation(GO:0001923) B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.0 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.0 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0071559 response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.0 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0021510 spinal cord development(GO:0021510)
0.0 0.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.6 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:2000757 negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.3 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.0 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.6 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 0.5 GO:0036128 CatSper complex(GO:0036128)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0005694 chromosome(GO:0005694)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.3 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.0 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 1.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.2 0.8 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.8 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.6 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.5 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.0 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.0 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.2 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.0 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.2 PID_MYC_PATHWAY C-MYC pathway
0.0 0.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 2.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.2 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis