Motif ID: MEIS1

Z-value: 0.557


Transcription factors associated with MEIS1:

Gene SymbolEntrez IDGene Name
MEIS1 ENSG00000143995.15 MEIS1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEIS1hg19_v2_chr2_+_66662690_66662711-0.462.4e-02Click!


Activity profile for motif MEIS1.

activity profile for motif MEIS1


Sorted Z-values histogram for motif MEIS1

Sorted Z-values for motif MEIS1



Network of associatons between targets according to the STRING database.



First level regulatory network of MEIS1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_113594279 1.135 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr5_+_7654057 1.064 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr12_-_57634475 0.808 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr19_-_51538118 0.759 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr19_-_51538148 0.730 ENST00000319590.4
ENST00000250351.4
KLK12

kallikrein-related peptidase 12

chr1_+_203651937 0.728 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr10_+_54074033 0.681 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr2_+_33359687 0.667 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr2_+_113885138 0.657 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr2_+_33359646 0.648 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr20_-_7921090 0.634 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr19_-_51537982 0.625 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr17_-_76899275 0.623 ENST00000322630.2
ENST00000586713.1
DDC8

Protein DDC8 homolog

chr16_+_30194916 0.619 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A


coronin, actin binding protein, 1A


chr5_+_150404904 0.584 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr8_+_31497271 0.579 ENST00000520407.1
NRG1
neuregulin 1
chr1_+_17531614 0.571 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr4_-_159956333 0.571 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr10_-_33623564 0.568 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr11_+_35198243 0.546 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr2_+_210444142 0.541 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr3_-_47934234 0.522 ENST00000420772.2
MAP4
microtubule-associated protein 4
chrX_+_135251783 0.505 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr2_-_118943930 0.498 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1


AC093901.1


chr9_-_22009241 0.487 ENST00000380142.4
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr15_+_59397275 0.487 ENST00000288207.2
CCNB2
cyclin B2
chr17_-_53809473 0.486 ENST00000575734.1
TMEM100
transmembrane protein 100
chr11_-_107729887 0.477 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr20_+_33759854 0.466 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr16_+_8814563 0.458 ENST00000425191.2
ENST00000569156.1
ABAT

4-aminobutyrate aminotransferase

chrX_+_41548220 0.455 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chrX_+_41548259 0.454 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr4_-_175443943 0.445 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr10_+_120967072 0.443 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr9_-_72287191 0.442 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr4_+_75311019 0.437 ENST00000502307.1
AREG
amphiregulin
chr7_-_142247606 0.436 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr18_+_47088401 0.434 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr15_+_57884117 0.434 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr14_+_24540731 0.434 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6




copine VI (neuronal)




chr14_-_94421923 0.432 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chrX_+_135251835 0.429 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr11_-_31832581 0.427 ENST00000379111.2
PAX6
paired box 6
chr21_-_32931290 0.426 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr1_-_153113927 0.418 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr6_-_26124138 0.416 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr15_+_97326659 0.416 ENST00000558553.1
SPATA8
spermatogenesis associated 8
chr2_+_70142232 0.415 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr19_+_4402659 0.415 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr6_+_53948328 0.414 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr10_-_131762105 0.409 ENST00000368648.3
ENST00000355311.5
EBF3

early B-cell factor 3

chr6_-_30654977 0.407 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr15_+_59397298 0.406 ENST00000559622.1
CCNB2
cyclin B2
chr11_-_31832862 0.398 ENST00000379115.4
PAX6
paired box 6
chr14_+_85996471 0.395 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr4_-_23891658 0.390 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_31832785 0.389 ENST00000241001.8
PAX6
paired box 6
chr2_+_234959323 0.387 ENST00000373368.1
ENST00000168148.3
SPP2

secreted phosphoprotein 2, 24kDa

chr12_+_41086297 0.386 ENST00000551295.2
CNTN1
contactin 1
chr3_+_100328433 0.384 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr1_+_152974218 0.379 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3


small proline-rich protein 3


chr14_+_24540046 0.378 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6



copine VI (neuronal)



chr4_-_175443788 0.373 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr6_-_134861089 0.372 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr5_+_68463043 0.371 ENST00000508407.1
ENST00000505500.1
CCNB1

cyclin B1

chr19_-_55660561 0.370 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1






troponin T type 1 (skeletal, slow)






chr14_+_52164820 0.368 ENST00000554167.1
FRMD6
FERM domain containing 6
chr2_+_113735575 0.366 ENST00000376489.2
ENST00000259205.4
IL36G

interleukin 36, gamma

chrX_+_135614293 0.362 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr11_-_123756334 0.362 ENST00000528595.1
ENST00000375026.2
TMEM225

transmembrane protein 225

chrX_+_152082969 0.360 ENST00000535861.1
ENST00000539731.1
ENST00000449285.2
ENST00000318504.7
ENST00000324823.6
ENST00000370268.4
ENST00000370270.2
ZNF185






zinc finger protein 185 (LIM domain)






chr5_+_66124590 0.352 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr19_+_16308659 0.351 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1


adaptor-related protein complex 1, mu 1 subunit


chr1_+_26605618 0.350 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr12_+_101188718 0.350 ENST00000299222.9
ENST00000392977.3
ANO4

anoctamin 4

chr20_+_58630972 0.342 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr4_+_14113592 0.341 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085



long intergenic non-protein coding RNA 1085



chr4_-_175443484 0.340 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD




hydroxyprostaglandin dehydrogenase 15-(NAD)




chr7_+_142031986 0.340 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr1_-_150978953 0.340 ENST00000493834.2
FAM63A
family with sequence similarity 63, member A
chr11_-_31832207 0.338 ENST00000379109.2
PAX6
paired box 6
chr17_-_7297833 0.336 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chrX_+_107069063 0.335 ENST00000262843.6
MID2
midline 2
chr2_+_102456277 0.331 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr11_-_19262486 0.330 ENST00000250024.4
E2F8
E2F transcription factor 8
chr19_+_16308711 0.329 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1


adaptor-related protein complex 1, mu 1 subunit


chr12_-_91505608 0.328 ENST00000266718.4
LUM
lumican
chr17_+_7942335 0.327 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B


arachidonate 15-lipoxygenase, type B


chr17_+_7942424 0.326 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr7_+_110731062 0.325 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3



leucine rich repeat neuronal 3



chr3_-_196014520 0.321 ENST00000441879.1
ENST00000292823.2
ENST00000411591.1
ENST00000431016.1
ENST00000443555.1
PCYT1A




phosphate cytidylyltransferase 1, choline, alpha




chr6_+_106546808 0.320 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr5_-_175843569 0.318 ENST00000310418.4
ENST00000345807.2
CLTB

clathrin, light chain B

chr13_+_32313658 0.318 ENST00000380314.1
ENST00000298386.2
RXFP2

relaxin/insulin-like family peptide receptor 2

chr17_-_47286729 0.316 ENST00000300406.2
ENST00000511277.1
ENST00000511673.1
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chrX_-_72299258 0.315 ENST00000453389.1
ENST00000373519.1
PABPC1L2A

poly(A) binding protein, cytoplasmic 1-like 2A

chr1_-_111991850 0.315 ENST00000411751.2
WDR77
WD repeat domain 77
chr7_-_121944491 0.314 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr15_-_70994612 0.311 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA


uveal autoantigen with coiled-coil domains and ankyrin repeats


chr21_+_30502806 0.309 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr3_+_111578131 0.307 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr11_+_35198118 0.306 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44



CD44 molecule (Indian blood group)



chr12_+_79439405 0.306 ENST00000552744.1
SYT1
synaptotagmin I
chr19_-_42927251 0.303 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr4_-_39033963 0.302 ENST00000381938.3
TMEM156
transmembrane protein 156
chr1_-_93426998 0.302 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr10_+_81272287 0.301 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr14_-_50154921 0.300 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2



polymerase (DNA directed), epsilon 2, accessory subunit



chr1_-_153085984 0.299 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr13_+_78109884 0.298 ENST00000377246.3
ENST00000349847.3
SCEL

sciellin

chr18_+_32455201 0.293 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr1_+_153003671 0.292 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr19_+_48867652 0.290 ENST00000344846.2
SYNGR4
synaptogyrin 4
chr20_-_39946237 0.289 ENST00000441102.2
ENST00000559234.1
ZHX3

zinc fingers and homeoboxes 3

chr12_+_4647950 0.289 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51AP1




RAD51 associated protein 1




chr13_+_78109804 0.288 ENST00000535157.1
SCEL
sciellin
chr6_+_31126291 0.284 ENST00000376257.3
ENST00000376255.4
TCF19

transcription factor 19

chr11_+_35211429 0.283 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44


CD44 molecule (Indian blood group)


chr18_+_61445007 0.283 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr18_-_47807829 0.281 ENST00000585672.1
ENST00000457839.2
ENST00000353909.3
ENST00000339998.6
ENST00000398493.1
MBD1




methyl-CpG binding domain protein 1




chr5_+_96079240 0.281 ENST00000515663.1
CAST
calpastatin
chr14_+_75745477 0.278 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chr4_+_88896819 0.277 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1



secreted phosphoprotein 1



chr2_-_161056762 0.277 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr2_+_208576259 0.276 ENST00000392209.3
CCNYL1
cyclin Y-like 1
chr15_+_67458357 0.276 ENST00000537194.2
SMAD3
SMAD family member 3
chrX_+_70503037 0.274 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr1_+_165796753 0.272 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr5_-_175843524 0.272 ENST00000502877.1
CLTB
clathrin, light chain B
chr4_-_4291761 0.270 ENST00000513174.1
LYAR
Ly1 antibody reactive
chr8_-_144655141 0.269 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr20_+_42295745 0.269 ENST00000396863.4
ENST00000217026.4
MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

chr11_+_35211511 0.269 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr8_-_125577940 0.267 ENST00000519168.1
ENST00000395508.2
MTSS1

metastasis suppressor 1

chr1_+_212208919 0.266 ENST00000366991.4
ENST00000542077.1
DTL

denticleless E3 ubiquitin protein ligase homolog (Drosophila)

chr2_+_233925064 0.266 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr4_-_69111401 0.263 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr9_+_34652164 0.262 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr8_-_7287870 0.261 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr14_+_104029362 0.260 ENST00000495778.1
APOPT1
apoptogenic 1, mitochondrial
chr9_-_22009297 0.260 ENST00000276925.6
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr21_+_43823983 0.258 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A



ubiquitin associated and SH3 domain containing A



chr12_-_51785182 0.257 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6



UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)



chr5_+_82767284 0.256 ENST00000265077.3
VCAN
versican
chr12_+_101188547 0.256 ENST00000546991.1
ENST00000392979.3
ANO4

anoctamin 4

chr1_-_197036364 0.256 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr17_+_40610862 0.256 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1








ATPase, H+ transporting, lysosomal V0 subunit a1








chr2_-_68547061 0.254 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr14_+_92980111 0.254 ENST00000216487.7
ENST00000557762.1
RIN3

Ras and Rab interactor 3

chr3_-_48632593 0.254 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr12_+_100041527 0.251 ENST00000324341.1
FAM71C
family with sequence similarity 71, member C
chr11_+_67195917 0.250 ENST00000524934.1
ENST00000539188.1
ENST00000312629.5
RPS6KB2


ribosomal protein S6 kinase, 70kDa, polypeptide 2


chr19_-_57988871 0.249 ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
ENST00000596831.1
ZNF772





AC004076.9
zinc finger protein 772





Uncharacterized protein
chr18_-_67872891 0.249 ENST00000454359.1
ENST00000437017.1
RTTN

rotatin

chr11_+_65686952 0.248 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr16_+_55600580 0.247 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr1_+_15736359 0.246 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr2_-_119605253 0.246 ENST00000295206.6
EN1
engrailed homeobox 1
chr7_+_142457315 0.246 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr12_+_21679220 0.245 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr4_-_4291748 0.244 ENST00000452476.1
LYAR
Ly1 antibody reactive
chr7_+_147830776 0.242 ENST00000538075.1
CNTNAP2
contactin associated protein-like 2
chr3_-_52090461 0.242 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr9_+_116263639 0.241 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr18_+_61420169 0.239 ENST00000425392.1
ENST00000336429.2
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr5_+_82767487 0.239 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chrX_+_44703249 0.239 ENST00000339042.4
DUSP21
dual specificity phosphatase 21
chr2_+_234959376 0.236 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr9_+_116263778 0.235 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr11_-_113577052 0.234 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5



transmembrane protease, serine 5



chr4_-_156787425 0.233 ENST00000537611.2
ASIC5
acid-sensing (proton-gated) ion channel family member 5
chr11_+_4116005 0.233 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr11_+_4116054 0.233 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr1_+_156863470 0.233 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
PEAR1


platelet endothelial aggregation receptor 1


chrX_+_41306575 0.232 ENST00000342595.2
ENST00000378220.1
NYX

nyctalopin

chr12_-_76953453 0.231 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr21_-_47352477 0.231 ENST00000593412.1
PRED62
Uncharacterized protein
chr18_+_61554932 0.230 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr1_+_154377669 0.230 ENST00000368485.3
ENST00000344086.4
IL6R

interleukin 6 receptor

chr15_+_57884086 0.229 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1





GRINL1A complex locus 1





chr2_-_85636928 0.228 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr6_-_11382478 0.228 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9



neural precursor cell expressed, developmentally down-regulated 9



chr1_+_74701062 0.227 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr8_+_11666649 0.227 ENST00000528643.1
ENST00000525777.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr3_-_49066811 0.227 ENST00000442157.1
ENST00000326739.4
IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

chr2_+_158114051 0.225 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr2_-_161056802 0.223 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr3_+_111578027 0.223 ENST00000431670.2
ENST00000412622.1
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr19_+_10765003 0.223 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr11_-_568369 0.222 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr10_+_49892904 0.222 ENST00000360890.2
WDFY4
WDFY family member 4
chr19_+_10764937 0.221 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr2_-_68694390 0.220 ENST00000377957.3
FBXO48
F-box protein 48
chr16_+_30006997 0.219 ENST00000304516.7
INO80E
INO80 complex subunit E
chr12_+_75874460 0.219 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr7_+_150811705 0.217 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr7_+_145813453 0.217 ENST00000361727.3
CNTNAP2
contactin associated protein-like 2
chr6_+_106534192 0.215 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr2_+_115199876 0.214 ENST00000436732.1
ENST00000410059.1
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr17_-_58469687 0.214 ENST00000590133.1
USP32
ubiquitin specific peptidase 32

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.7 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 0.9 GO:0061743 motor learning(GO:0061743)
0.2 1.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.8 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 1.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.4 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.5 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.5 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.8 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.3 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.6 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.1 0.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.5 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.1 GO:1903800 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.3 GO:1902728 positive regulation of skeletal muscle cell proliferation(GO:0014858) mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.2 GO:0035359 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.3 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.5 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.3 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 4.7 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.7 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.0 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.0 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0035166 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166)
0.0 1.0 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.7 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.7 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0001890 placenta development(GO:0001890)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.0 0.0 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0035546 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.1 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.0 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0002200 somatic diversification of immune receptors(GO:0002200)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 1.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.0 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 0.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 2.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.3 GO:0043219 myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.0 GO:0000806 Y chromosome(GO:0000806)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.0 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0044431 Golgi apparatus part(GO:0044431)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 1.3 GO:0050436 microfibril binding(GO:0050436)
0.2 0.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 0.7 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 0.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0031013 troponin I binding(GO:0031013)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 3.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.1 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.6 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.4 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.0 PID_S1P_S1P2_PATHWAY S1P2 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.9 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.2 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.0 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends