Motif ID: MEF2D_MEF2A

Z-value: 0.629

Transcription factors associated with MEF2D_MEF2A:

Gene SymbolEntrez IDGene Name
MEF2A ENSG00000068305.13 MEF2A
MEF2D ENSG00000116604.13 MEF2D

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEF2Ahg19_v2_chr15_+_100106155_100106243-0.291.7e-01Click!
MEF2Dhg19_v2_chr1_-_156460391_1564604170.174.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_131200810 1.324 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr2_+_233497931 0.827 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr1_-_201391149 0.823 ENST00000555948.1
ENST00000556362.1
TNNI1

troponin I type 1 (skeletal, slow)

chr7_-_113559104 0.795 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr14_+_24540731 0.731 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6




copine VI (neuronal)




chr3_-_108248169 0.651 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr3_+_35683651 0.617 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_121944491 0.576 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr17_+_37821593 0.568 ENST00000578283.1
TCAP
titin-cap
chr4_-_23891658 0.529 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_+_7184986 0.510 ENST00000317370.8
ENST00000571308.1
SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

chr9_-_104145795 0.488 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr11_-_19223523 0.476 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr17_+_34538310 0.450 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1











chemokine (C-C motif) ligand 4-like 1











chr3_+_138067666 0.435 ENST00000475711.1
ENST00000464896.1
MRAS

muscle RAS oncogene homolog

chr1_-_25756638 0.423 ENST00000349320.3
RHCE
Rh blood group, CcEe antigens
chr17_-_72855989 0.419 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr11_+_129245796 0.413 ENST00000281437.4
BARX2
BARX homeobox 2
chr2_-_211168332 0.401 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr3_+_138067314 0.398 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr14_+_76776957 0.393 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr17_+_34639793 0.392 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2


chemokine (C-C motif) ligand 4-like 2


chr17_+_34640031 0.388 ENST00000339270.6
ENST00000482104.1
CCL4L2

chemokine (C-C motif) ligand 4-like 2

chr7_+_143013198 0.375 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr10_-_75415825 0.373 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr11_+_1942580 0.365 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr8_+_1993152 0.358 ENST00000262113.4
MYOM2
myomesin 2
chr3_+_138067521 0.350 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr8_+_1993173 0.347 ENST00000523438.1
MYOM2
myomesin 2
chr2_-_190044480 0.346 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr8_+_7716700 0.335 ENST00000454911.2
ENST00000326625.5
SPAG11A

sperm associated antigen 11A

chr12_-_45269430 0.333 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr3_+_99357319 0.328 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1


collagen, type VIII, alpha 1


chr16_-_31439735 0.322 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr2_-_165424973 0.318 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chrX_-_21776281 0.315 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr8_+_95565947 0.312 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr10_+_118187379 0.311 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr7_+_18535893 0.300 ENST00000432645.2
ENST00000441542.2
HDAC9

histone deacetylase 9

chr6_-_33160231 0.300 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chr5_+_155753745 0.300 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr2_+_33661382 0.295 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr13_-_46756351 0.294 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr18_+_12407895 0.293 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1



slowmo homolog 1 (Drosophila)



chr2_+_168043793 0.286 ENST00000409273.1
ENST00000409605.1
XIRP2

xin actin-binding repeat containing 2

chr3_+_50316458 0.272 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr2_-_211179883 0.272 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr1_+_95583479 0.268 ENST00000455656.1
ENST00000604534.1
TMEM56
RP11-57H12.6
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr10_-_75410771 0.265 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr1_+_114522049 0.261 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr8_-_7309887 0.259 ENST00000458665.1
ENST00000528168.1
SPAG11B

sperm associated antigen 11B

chr4_+_120056939 0.258 ENST00000307128.5
MYOZ2
myozenin 2
chr2_+_88367299 0.250 ENST00000419482.2
ENST00000444564.2
SMYD1

SET and MYND domain containing 1

chr17_-_34345002 0.247 ENST00000293280.2
CCL23
chemokine (C-C motif) ligand 23
chr15_-_70994612 0.247 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA


uveal autoantigen with coiled-coil domains and ankyrin repeats


chr2_+_220299547 0.245 ENST00000312358.7
SPEG
SPEG complex locus
chr7_-_37488834 0.245 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr17_-_34344991 0.243 ENST00000591423.1
CCL23
chemokine (C-C motif) ligand 23
chr21_-_34186006 0.235 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr11_+_128563652 0.232 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr9_+_116327326 0.230 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chrX_-_15332665 0.229 ENST00000537676.1
ENST00000344384.4
ASB11

ankyrin repeat and SOCS box containing 11

chr17_-_27949911 0.228 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6


coronin 6


chr11_+_57308979 0.217 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr2_-_31637560 0.216 ENST00000379416.3
XDH
xanthine dehydrogenase
chr14_-_65409502 0.214 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr12_-_371994 0.214 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13



solute carrier family 6 (neurotransmitter transporter), member 13



chr1_+_150254936 0.211 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr1_-_100643765 0.204 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39


leucine rich repeat containing 39


chr9_+_129677123 0.199 ENST00000373436.1
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr1_+_145413268 0.197 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2



hemochromatosis type 2 (juvenile)



chr6_-_76203345 0.194 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr4_+_37892682 0.194 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr6_-_55739542 0.193 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr15_-_83474806 0.193 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2


fibronectin type III and SPRY domain containing 2


chr19_-_18209626 0.190 ENST00000598019.2
ENST00000594176.1
ENST00000600835.2
IL12RB1


interleukin 12 receptor, beta 1


chr5_-_150521192 0.186 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr5_+_53751445 0.186 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr6_+_44194762 0.184 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr11_+_124481361 0.184 ENST00000284288.2
PANX3
pannexin 3
chr10_-_3827371 0.184 ENST00000469435.1
KLF6
Kruppel-like factor 6
chr18_-_35145981 0.181 ENST00000420428.2
ENST00000412753.1
CELF4

CUGBP, Elav-like family member 4

chr1_-_917497 0.181 ENST00000433179.2
C1orf170
chromosome 1 open reading frame 170
chr7_+_99775366 0.178 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chrX_-_63450480 0.178 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr1_-_169703203 0.176 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE




selectin E




chr18_-_44181442 0.176 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr19_-_47975417 0.176 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_+_26348259 0.175 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr16_+_12059091 0.174 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr11_+_1940925 0.173 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3





troponin T type 3 (skeletal, fast)





chr1_-_201390846 0.171 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1


troponin I type 1 (skeletal, slow)


chrX_+_135570046 0.170 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr7_+_99775520 0.167 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr7_-_44105158 0.166 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr17_+_42248063 0.165 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr20_-_44519839 0.165 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr17_-_1389228 0.164 ENST00000438665.2
MYO1C
myosin IC
chr1_+_203097407 0.164 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr1_-_116383322 0.164 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr16_+_84328252 0.163 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr16_+_84328429 0.161 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr1_-_917466 0.158 ENST00000341290.2
C1orf170
chromosome 1 open reading frame 170
chr6_-_45983581 0.158 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr6_+_152128686 0.156 ENST00000206249.3
ESR1
estrogen receptor 1
chr8_-_27850141 0.156 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr12_+_15699286 0.156 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr18_+_13611431 0.156 ENST00000587757.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_-_10421853 0.154 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr14_-_65409438 0.154 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr2_-_219696511 0.153 ENST00000439262.2
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr6_+_132129151 0.153 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr4_-_122302163 0.152 ENST00000394427.2
QRFPR
pyroglutamylated RFamide peptide receptor
chr4_-_143226979 0.151 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_+_8543533 0.151 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr7_+_123488124 0.150 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr20_+_44657845 0.150 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr3_+_36421826 0.149 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr1_+_175036966 0.149 ENST00000239462.4
TNN
tenascin N
chr5_-_16509101 0.148 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr8_-_27115931 0.146 ENST00000523048.1
STMN4
stathmin-like 4
chr6_-_76203454 0.143 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr2_-_219696519 0.142 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3


protein kinase, AMP-activated, gamma 3 non-catalytic subunit


chr3_+_135741576 0.142 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr8_+_27183033 0.139 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr1_+_35258592 0.139 ENST00000342280.4
ENST00000450137.1
GJA4

gap junction protein, alpha 4, 37kDa

chr8_+_27182862 0.138 ENST00000521164.1
ENST00000346049.5
PTK2B

protein tyrosine kinase 2 beta

chr15_-_99057551 0.135 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr11_-_62457371 0.135 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr6_+_152128371 0.134 ENST00000443427.1
ESR1
estrogen receptor 1
chr13_-_103346854 0.134 ENST00000267273.6
METTL21C
methyltransferase like 21C
chr10_-_45474237 0.133 ENST00000448778.1
ENST00000298295.3
C10orf10

chromosome 10 open reading frame 10

chr7_+_39125365 0.133 ENST00000559001.1
ENST00000464276.2
POU6F2

POU class 6 homeobox 2

chr1_-_152131703 0.133 ENST00000316073.3
RPTN
repetin
chr8_-_42234745 0.133 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr1_+_182584314 0.132 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr4_+_119809984 0.132 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2


synaptopodin 2


chr18_-_35145728 0.131 ENST00000361795.5
ENST00000603232.1
CELF4

CUGBP, Elav-like family member 4

chrX_-_50386648 0.131 ENST00000460112.3
SHROOM4
shroom family member 4
chr3_+_132843652 0.128 ENST00000508711.1
TMEM108
transmembrane protein 108
chr17_-_10325261 0.127 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr12_+_80750134 0.125 ENST00000546620.1
OTOGL
otogelin-like
chr4_+_8321882 0.125 ENST00000503186.1
ENST00000509453.1
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
chr6_-_116833500 0.124 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr7_+_30951461 0.124 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr3_+_8543393 0.124 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1


LIM and cysteine-rich domains 1


chr6_+_136172820 0.122 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr14_+_39735411 0.121 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr21_+_17909594 0.119 ENST00000441820.1
ENST00000602280.1
LINC00478

long intergenic non-protein coding RNA 478

chr4_+_88529681 0.119 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr10_+_71562180 0.117 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1


collagen, type XIII, alpha 1


chr6_+_159291090 0.117 ENST00000367073.4
ENST00000608817.1
C6orf99

chromosome 6 open reading frame 99

chr21_-_34185944 0.116 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr3_+_35721182 0.116 ENST00000413378.1
ENST00000417925.1
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr2_+_30569506 0.116 ENST00000421976.2
AC109642.1
AC109642.1
chr10_-_69455873 0.114 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr17_-_38821373 0.113 ENST00000394052.3
KRT222
keratin 222
chr12_+_81101277 0.113 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr6_-_169654139 0.113 ENST00000366787.3
THBS2
thrombospondin 2
chr5_+_161274940 0.112 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_88428370 0.112 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr7_-_105332084 0.112 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr5_-_131347501 0.111 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr15_+_59730348 0.111 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chr17_-_1389419 0.110 ENST00000575158.1
MYO1C
myosin IC
chr6_+_159290917 0.109 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr6_-_27806117 0.109 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr7_+_154002189 0.109 ENST00000332007.3
DPP6
dipeptidyl-peptidase 6
chr10_-_3827417 0.108 ENST00000497571.1
ENST00000542957.1
KLF6

Kruppel-like factor 6

chr13_-_97646604 0.108 ENST00000298440.1
ENST00000543457.1
ENST00000541038.1
OXGR1


oxoglutarate (alpha-ketoglutarate) receptor 1


chr14_-_57277178 0.108 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2


orthodenticle homeobox 2


chr17_-_10276319 0.106 ENST00000252172.4
ENST00000418404.3
MYH13

myosin, heavy chain 13, skeletal muscle

chr19_+_3933085 0.105 ENST00000168977.2
ENST00000599576.1
NMRK2

nicotinamide riboside kinase 2

chr12_-_55367361 0.104 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1


thymocyte expressed, positive selection associated 1


chr11_-_47400078 0.103 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr5_-_131347306 0.103 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6



acyl-CoA synthetase long-chain family member 6



chr17_+_27369918 0.101 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr3_-_57326704 0.101 ENST00000487349.1
ENST00000389601.3
ASB14

ankyrin repeat and SOCS box containing 14

chr11_-_35440579 0.101 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_18535346 0.100 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9


histone deacetylase 9


chr2_+_220144052 0.098 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2


DnaJ (Hsp40) homolog, subfamily B, member 2


chr9_+_21440440 0.096 ENST00000276927.1
IFNA1
interferon, alpha 1
chr14_+_56046914 0.096 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1



kinectin 1 (kinesin receptor)



chr8_+_74903580 0.095 ENST00000284818.2
ENST00000518893.1
LY96

lymphocyte antigen 96

chr11_+_112832202 0.094 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chrX_+_105192423 0.094 ENST00000540278.1
NRK
Nik related kinase
chr12_-_45270151 0.093 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr15_+_78830023 0.092 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr2_-_29297127 0.092 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr7_+_5465382 0.091 ENST00000609130.1
RP11-1275H24.2
RP11-1275H24.2
chr11_+_1940786 0.090 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3




troponin T type 3 (skeletal, fast)




chr6_+_123038689 0.090 ENST00000354275.2
ENST00000368446.1
PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr12_-_91539918 0.090 ENST00000548218.1
DCN
decorin
chr1_+_151129103 0.090 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr1_+_150245177 0.090 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chrY_-_23548246 0.089 ENST00000382764.1
CYorf17
chromosome Y open reading frame 17
chr16_+_3194211 0.088 ENST00000428155.1
CASP16
caspase 16, apoptosis-related cysteine peptidase (putative)
chr2_+_11864458 0.088 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1


lipin 1


chr7_+_95115210 0.087 ENST00000428113.1
ENST00000325885.5
ASB4

ankyrin repeat and SOCS box containing 4

chr19_-_51220176 0.085 ENST00000359082.3
ENST00000293441.1
SHANK1

SH3 and multiple ankyrin repeat domains 1


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.9 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.1 0.5 GO:0019530 taurine metabolic process(GO:0019530)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.4 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.3 GO:1903799 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0033594 response to vitamin K(GO:0032571) response to hydroxyisoflavone(GO:0033594)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.7 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.2 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.1 0.2 GO:0031674 I band(GO:0031674)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.8 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.1 0.5 GO:0031433 telethonin binding(GO:0031433)
0.1 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 0.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.5 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling