Motif ID: MEF2C
Z-value: 0.698

Transcription factors associated with MEF2C:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MEF2C | ENSG00000081189.9 | MEF2C |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
MEF2C | hg19_v2_chr5_-_88119580_88119605 | -0.29 | 1.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 66 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 7.0 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.0 | 1.8 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.0 | 1.6 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 1.6 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
0.0 | 1.5 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.1 | 1.2 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.0 | 1.2 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
0.0 | 1.1 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
0.3 | 0.8 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.0 | 0.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.0 | 0.8 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.8 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.7 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
0.1 | 0.6 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.1 | 0.6 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.0 | 0.6 | GO:0086069 | bundle of His cell to Purkinje myocyte communication(GO:0086069) |
0.0 | 0.6 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.2 | 0.5 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
0.2 | 0.5 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.5 | GO:0046449 | creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 29 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.5 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 1.3 | GO:0005861 | troponin complex(GO:0005861) |
0.1 | 1.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.2 | 1.0 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
0.1 | 0.8 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.7 | GO:0031430 | M band(GO:0031430) |
0.1 | 0.6 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
0.1 | 0.6 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 0.6 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 0.6 | GO:0016460 | myosin II complex(GO:0016460) |
0.2 | 0.5 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 0.5 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.1 | 0.4 | GO:0045160 | myosin I complex(GO:0045160) |
0.1 | 0.4 | GO:0030427 | growth cone(GO:0030426) site of polarized growth(GO:0030427) |
0.0 | 0.4 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 0.3 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 0.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.2 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 50 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 7.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.3 | 1.9 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
0.1 | 1.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.2 | 0.8 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
0.1 | 0.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.0 | 0.8 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.7 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.2 | 0.6 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.0 | 0.6 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.0 | 0.6 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.1 | 0.5 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.1 | 0.5 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
0.0 | 0.5 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 0.4 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
0.1 | 0.4 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.1 | 0.4 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.0 | 0.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.0 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.0 | 0.4 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
Gene overrepresentation in C2:CP category:
Showing 1 to 6 of 6 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.8 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 1.4 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.6 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.5 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 0.3 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 8 of 8 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 1.8 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 1.4 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.4 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | Genes involved in Extracellular matrix organization |
0.0 | 0.3 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.0 | 0.2 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |