Motif ID: LHX2

Z-value: 0.373


Transcription factors associated with LHX2:

Gene SymbolEntrez IDGene Name
LHX2 ENSG00000106689.6 LHX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX2hg19_v2_chr9_+_126777676_126777700,
hg19_v2_chr9_+_126773880_126773895
-0.145.0e-01Click!


Activity profile for motif LHX2.

activity profile for motif LHX2


Sorted Z-values histogram for motif LHX2

Sorted Z-values for motif LHX2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_38859996 1.770 ENST00000264651.2
KRT24
keratin 24
chr18_+_29027696 1.305 ENST00000257189.4
DSG3
desmoglein 3
chr4_+_69313145 1.246 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr6_-_131291572 0.782 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr6_+_53883790 0.710 ENST00000509997.1
MLIP
muscular LMNA-interacting protein
chr9_+_105757590 0.677 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr19_+_15838834 0.638 ENST00000305899.3
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr1_+_152975488 0.606 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr3_+_57882024 0.586 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr6_+_53883708 0.541 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP


muscular LMNA-interacting protein


chr19_+_42212501 0.493 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr11_-_62323702 0.459 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr14_-_34420259 0.447 ENST00000250457.3
ENST00000547327.2
EGLN3

egl-9 family hypoxia-inducible factor 3

chr6_+_26199737 0.436 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr19_+_42212526 0.434 ENST00000221992.6
ENST00000405816.1
ENST00000598976.1
ENST00000435837.2
CEACAM5

CEA

carcinoembryonic antigen-related cell adhesion molecule 5

Uncharacterized protein

chr4_-_109541539 0.428 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1


RPL34 antisense RNA 1 (head to head)


chr18_+_34124507 0.428 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr1_+_62439037 0.414 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_+_192127578 0.412 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr14_+_56584414 0.408 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr2_+_102953608 0.377 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr4_-_159956333 0.361 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr12_+_122688090 0.351 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr4_+_88532028 0.349 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr10_+_95326416 0.333 ENST00000371481.4
ENST00000371483.4
ENST00000604414.1
FFAR4


free fatty acid receptor 4


chr10_-_24770632 0.309 ENST00000596413.1
AL353583.1
AL353583.1
chr8_+_22424551 0.307 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr3_+_62936098 0.301 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
LINC00698



long intergenic non-protein coding RNA 698



chr17_+_17082842 0.300 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr10_-_90712520 0.299 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_-_198509804 0.292 ENST00000489986.1
ENST00000367382.1
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr17_-_57229155 0.281 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr6_+_123038689 0.279 ENST00000354275.2
ENST00000368446.1
PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr12_-_118797475 0.279 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr11_+_31391381 0.279 ENST00000465995.1
ENST00000536040.1
DNAJC24

DnaJ (Hsp40) homolog, subfamily C, member 24

chr12_+_128399965 0.277 ENST00000540882.1
ENST00000542089.1
LINC00507

long intergenic non-protein coding RNA 507

chr21_-_31859755 0.275 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr6_-_66417107 0.268 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr12_-_10978957 0.262 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr4_-_89951028 0.259 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr17_+_61086917 0.257 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr2_+_210517895 0.257 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr9_+_116207007 0.251 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr17_-_39222131 0.250 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr3_-_149095652 0.250 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr4_-_90756769 0.246 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr14_-_51027838 0.243 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr11_+_63606373 0.224 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr17_-_39140549 0.222 ENST00000377755.4
KRT40
keratin 40
chr9_-_21202204 0.214 ENST00000239347.3
IFNA7
interferon, alpha 7
chr8_-_93029865 0.214 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_4828815 0.213 ENST00000533295.1
AKR1E2
aldo-keto reductase family 1, member E2
chr2_-_112237835 0.212 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG

MIR4435-1 host gene (non-protein coding)

chr10_-_29923893 0.206 ENST00000355867.4
SVIL
supervillin
chr10_-_14372870 0.206 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr9_-_77643307 0.199 ENST00000376834.3
ENST00000376830.3
C9orf41

chromosome 9 open reading frame 41

chr11_-_55703876 0.199 ENST00000301532.3
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr11_+_64001962 0.192 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr3_+_57881966 0.185 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr14_+_22554680 0.183 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr2_+_68961934 0.180 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr6_+_126661253 0.178 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW


centromere protein W


chr16_+_23652773 0.174 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
DCTN5


dynactin 5 (p25)


chr2_+_68961905 0.172 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_-_55237484 0.170 ENST00000394609.2
RTN4
reticulon 4
chr7_-_54826869 0.165 ENST00000450622.1
SEC61G
Sec61 gamma subunit
chr6_-_26027480 0.161 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr5_-_175388327 0.158 ENST00000432305.2
ENST00000505969.1
THOC3

THO complex 3

chr2_+_87769459 0.156 ENST00000414030.1
ENST00000437561.1
LINC00152

long intergenic non-protein coding RNA 152

chr12_+_12510352 0.150 ENST00000298571.6
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr6_+_125524785 0.147 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr6_-_26043885 0.143 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr9_-_116061476 0.143 ENST00000441031.3
RNF183
ring finger protein 183
chr7_-_54826920 0.143 ENST00000395535.3
ENST00000352861.4
SEC61G

Sec61 gamma subunit

chr11_+_120973375 0.141 ENST00000264037.2
TECTA
tectorin alpha
chr17_-_39216344 0.141 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chrX_-_19988382 0.140 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr4_-_100575781 0.140 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr6_+_105404899 0.140 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr15_+_58430567 0.137 ENST00000536493.1
AQP9
aquaporin 9
chr4_+_70796784 0.136 ENST00000246891.4
ENST00000444405.3
CSN1S1

casein alpha s1

chr21_-_27423339 0.136 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr7_+_37960163 0.136 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1


ependymin related 1


chr13_-_45768841 0.135 ENST00000379108.1
KCTD4
potassium channel tetramerization domain containing 4
chr13_-_19755975 0.135 ENST00000400113.3
TUBA3C
tubulin, alpha 3c
chrX_+_18725758 0.133 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr20_+_30697298 0.129 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr14_+_22573582 0.126 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr15_+_58430368 0.126 ENST00000558772.1
ENST00000219919.4
AQP9

aquaporin 9

chr4_+_128554081 0.125 ENST00000335251.6
ENST00000296461.5
INTU

inturned planar cell polarity protein

chr5_+_180682720 0.122 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr16_+_24741013 0.118 ENST00000315183.7
ENST00000395799.3
TNRC6A

trinucleotide repeat containing 6A

chr16_-_18887627 0.116 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr10_-_4285923 0.114 ENST00000418372.1
ENST00000608792.1
LINC00702

long intergenic non-protein coding RNA 702

chr2_-_55276320 0.113 ENST00000357376.3
RTN4
reticulon 4
chr12_-_113574028 0.110 ENST00000546530.1
ENST00000261729.5
RASAL1

RAS protein activator like 1 (GAP1 like)

chr18_+_3466248 0.109 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4


RP11-838N2.4


chr2_+_173686303 0.106 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr18_-_19994830 0.106 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr11_-_2323089 0.105 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr1_+_52682052 0.104 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr2_-_55496174 0.102 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2




mitochondrial translational initiation factor 2




chr13_+_19756173 0.097 ENST00000382988.2
RP11-408E5.4
RP11-408E5.4
chr12_+_128399917 0.093 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr16_+_23652700 0.092 ENST00000300087.2
DCTN5
dynactin 5 (p25)
chr12_-_10955226 0.091 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr4_-_120243545 0.090 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr2_+_234627424 0.090 ENST00000373409.3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr8_+_52730143 0.086 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr7_-_122840015 0.082 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr4_+_71226468 0.081 ENST00000226460.4
SMR3A
submaxillary gland androgen regulated protein 3A
chrX_-_11284095 0.081 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr19_+_20188830 0.080 ENST00000418063.2
ZNF90
zinc finger protein 90
chr4_+_147096837 0.079 ENST00000296581.5
ENST00000502781.1
LSM6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr17_-_33864772 0.079 ENST00000361112.4
SLFN12L
schlafen family member 12-like
chr14_+_101297740 0.078 ENST00000555928.1
MEG3
maternally expressed 3 (non-protein coding)
chr4_-_153332886 0.076 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_153518270 0.075 ENST00000354332.4
ENST00000368716.4
S100A4

S100 calcium binding protein A4

chr15_+_69854027 0.075 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr2_-_166930131 0.074 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chrX_+_105937068 0.074 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_95616933 0.072 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr2_+_87135076 0.070 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr3_-_160823040 0.070 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1






beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)






chr3_+_35722844 0.070 ENST00000436702.1
ENST00000438071.1
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr3_+_35722424 0.069 ENST00000396481.2
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_+_9980069 0.067 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1


killer cell lectin-like receptor subfamily F, member 1


chr8_-_19459993 0.065 ENST00000454498.2
ENST00000520003.1
CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr8_-_109260897 0.064 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E





eukaryotic translation initiation factor 3, subunit E





chr6_+_30848557 0.064 ENST00000460944.2
ENST00000324771.8
DDR1

discoidin domain receptor tyrosine kinase 1

chr2_+_90139056 0.063 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr7_-_103848405 0.062 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
ORC5


origin recognition complex, subunit 5


chr3_-_160823158 0.061 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1


beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)


chr16_-_23652570 0.060 ENST00000261584.4
PALB2
partner and localizer of BRCA2
chrX_-_20074895 0.059 ENST00000543767.1
MAP7D2
MAP7 domain containing 2
chr7_-_112758589 0.058 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
LINC00998


long intergenic non-protein coding RNA 998


chr14_+_69865401 0.051 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9


solute carrier family 39, member 9


chr3_+_38017264 0.051 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr21_+_35014783 0.050 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
ITSN1





intersectin 1 (SH3 domain protein)





chr11_-_104827425 0.046 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_45168875 0.045 ENST00000260653.3
SIX3
SIX homeobox 3
chr14_-_107211459 0.045 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr6_+_130339710 0.044 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chrX_+_30233668 0.044 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr5_-_159546396 0.044 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A


PWWP domain containing 2A


chr6_+_132873832 0.044 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr12_+_6554021 0.043 ENST00000266557.3
CD27
CD27 molecule
chr5_-_78281603 0.043 ENST00000264914.4
ARSB
arylsulfatase B
chr12_+_16064106 0.042 ENST00000428559.2
DERA
deoxyribose-phosphate aldolase (putative)
chr1_+_182419261 0.035 ENST00000294854.8
ENST00000542961.1
RGSL1

regulator of G-protein signaling like 1

chr12_-_74686314 0.033 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2


RP11-81H3.2


chr17_+_45000483 0.033 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
GOSR2







golgi SNAP receptor complex member 2







chr18_+_3247779 0.032 ENST00000578611.1
ENST00000583449.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr10_+_69865866 0.031 ENST00000354393.2
MYPN
myopalladin
chr8_-_82395461 0.031 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_44384291 0.029 ENST00000324394.6
ZNF404
zinc finger protein 404
chr6_+_3259148 0.026 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4



proteasome (prosome, macropain) assembly chaperone 4



chr4_+_70916119 0.024 ENST00000246896.3
ENST00000511674.1
HTN1

histatin 1

chr17_-_39324424 0.019 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chrX_+_19373700 0.016 ENST00000379804.1
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr7_-_151217166 0.016 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr2_+_74648848 0.014 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr5_+_179921344 0.013 ENST00000261951.4
CNOT6
CCR4-NOT transcription complex, subunit 6
chr21_-_35014027 0.012 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
CRYZL1







crystallin, zeta (quinone reductase)-like 1







chr9_-_28670283 0.012 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr1_-_147142557 0.010 ENST00000369238.6
ACP6
acid phosphatase 6, lysophosphatidic
chrX_+_52513455 0.007 ENST00000446098.1
XAGE1C
X antigen family, member 1C
chr2_-_231084659 0.007 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110



SP110 nuclear body protein



chr14_+_27342334 0.006 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1

RP11-384J4.1

chr3_+_33155444 0.005 ENST00000320954.6
CRTAP
cartilage associated protein
chr13_+_24844819 0.005 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr6_-_27841289 0.003 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr12_+_48722763 0.002 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific
chr1_+_145883868 0.002 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr12_-_118796910 0.002 ENST00000541186.1
ENST00000539872.1
TAOK3

TAO kinase 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.9 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 3.9 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.7 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.8 GO:0008091 spectrin(GO:0008091)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.9 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis