Motif ID: IRF7
Z-value: 0.902

Transcription factors associated with IRF7:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
IRF7 | ENSG00000185507.15 | IRF7 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
IRF7 | hg19_v2_chr11_-_615570_615728 | 0.07 | 7.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 193 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.7 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
0.9 | 3.6 | GO:0036269 | swimming behavior(GO:0036269) |
0.2 | 3.5 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.2 | 3.4 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
0.0 | 3.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.2 | 2.8 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.6 | 2.5 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
0.3 | 2.5 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.5 | 2.4 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
0.2 | 2.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
0.1 | 2.1 | GO:0046541 | saliva secretion(GO:0046541) |
0.7 | 2.0 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
0.1 | 1.9 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
0.4 | 1.8 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 1.7 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.4 | 1.6 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
0.2 | 1.6 | GO:2000334 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
0.0 | 1.6 | GO:0006536 | glutamate metabolic process(GO:0006536) |
0.3 | 1.5 | GO:0071105 | response to interleukin-11(GO:0071105) |
0.1 | 1.3 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 63 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
0.6 | 3.6 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.3 | 3.5 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.3 | 3.0 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.0 | 2.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 1.4 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 1.3 | GO:0031526 | brush border membrane(GO:0031526) |
0.1 | 1.1 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.0 | 1.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.2 | 0.9 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.9 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.1 | 0.8 | GO:0036021 | endolysosome lumen(GO:0036021) |
0.1 | 0.8 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
0.0 | 0.8 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
0.1 | 0.7 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.0 | 0.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 0.6 | GO:0042825 | TAP complex(GO:0042825) |
0.0 | 0.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.6 | GO:0070069 | cytochrome complex(GO:0070069) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 123 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
1.2 | 3.6 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
0.0 | 3.6 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.2 | 3.4 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
0.1 | 2.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.3 | 2.4 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.6 | 2.2 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
0.1 | 2.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.7 | 2.1 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
0.5 | 2.0 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
0.1 | 1.8 | GO:0070628 | proteasome binding(GO:0070628) |
0.3 | 1.7 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
0.3 | 1.6 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 1.6 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.1 | 1.5 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 1.5 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 1.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.1 | 1.4 | GO:0031386 | protein tag(GO:0031386) |
0.3 | 1.3 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
0.1 | 1.3 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 22 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.5 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 1.4 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 1.3 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 1.3 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.2 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.0 | 0.9 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.8 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.7 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.7 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.7 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.6 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.0 | 0.6 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 0.6 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.6 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.0 | 0.5 | ST_GA13_PATHWAY | G alpha 13 Pathway |
0.0 | 0.3 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 0.2 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 0.2 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.2 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 38 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.3 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |
0.3 | 3.9 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.2 | 3.7 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.1 | 3.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 2.4 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.1 | 2.3 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.0 | 1.5 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 1.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 1.0 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.1 | 0.9 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.0 | 0.9 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.8 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.7 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.7 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.0 | 0.7 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 0.6 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.1 | 0.5 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
0.0 | 0.5 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 0.5 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.0 | 0.5 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |