Motif ID: HOXC11

Z-value: 0.480


Transcription factors associated with HOXC11:

Gene SymbolEntrez IDGene Name
HOXC11 ENSG00000123388.4 HOXC11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXC11hg19_v2_chr12_+_54366894_54366922-0.433.8e-02Click!


Activity profile for motif HOXC11.

activity profile for motif HOXC11


Sorted Z-values histogram for motif HOXC11

Sorted Z-values for motif HOXC11



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_148521381 1.160 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr9_-_124989804 0.804 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr14_-_57272366 0.764 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2


orthodenticle homeobox 2


chr9_-_124976185 0.713 ENST00000464484.2
LHX6
LIM homeobox 6
chr9_-_124976154 0.704 ENST00000482062.1
LHX6
LIM homeobox 6
chr8_+_26435359 0.489 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr2_+_228678550 0.482 ENST00000409189.3
ENST00000358813.4
CCL20

chemokine (C-C motif) ligand 20

chr1_-_204135450 0.453 ENST00000272190.8
ENST00000367195.2
REN

renin

chr7_-_93519471 0.450 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr20_+_58179582 0.449 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr4_+_169013666 0.444 ENST00000359299.3
ANXA10
annexin A10
chr1_+_209878182 0.427 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_-_124990680 0.418 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr7_-_41742697 0.411 ENST00000242208.4
INHBA
inhibin, beta A
chr9_+_75229616 0.392 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr3_-_37216055 0.388 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr1_+_209859510 0.382 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr15_+_67418047 0.365 ENST00000540846.2
SMAD3
SMAD family member 3
chrX_-_107682702 0.363 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr7_+_134464414 0.346 ENST00000361901.2
CALD1
caldesmon 1
chr7_+_134464376 0.344 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr13_+_109248500 0.333 ENST00000356711.2
MYO16
myosin XVI
chr4_+_144354644 0.299 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr2_-_190044480 0.294 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_+_73706308 0.284 ENST00000554301.1
ENST00000555445.1
PAPLN

papilin, proteoglycan-like sulfated glycoprotein

chr10_+_17271266 0.282 ENST00000224237.5
VIM
vimentin
chr19_-_19626351 0.280 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr6_+_12290586 0.264 ENST00000379375.5
EDN1
endothelin 1
chr12_-_52779433 0.257 ENST00000257951.3
KRT84
keratin 84
chr6_+_31683117 0.253 ENST00000375825.3
ENST00000375824.1
LY6G6D

lymphocyte antigen 6 complex, locus G6D

chr21_-_31869451 0.245 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr8_+_42873548 0.227 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr6_+_88054530 0.223 ENST00000388923.4
C6orf163
chromosome 6 open reading frame 163
chr1_-_237167718 0.218 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr7_+_35756092 0.216 ENST00000458087.3
AC018647.3
AC018647.3
chrX_+_65382433 0.214 ENST00000374727.3
HEPH
hephaestin
chr3_-_51813009 0.205 ENST00000398780.3
IQCF6
IQ motif containing F6
chr7_-_81399411 0.195 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_+_158114051 0.192 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_-_94147385 0.192 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr1_-_9129895 0.190 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr10_-_24770632 0.190 ENST00000596413.1
AL353583.1
AL353583.1
chr14_-_25479811 0.185 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr19_+_1440838 0.185 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr12_+_130646999 0.185 ENST00000539839.1
ENST00000229030.4
FZD10

frizzled family receptor 10

chr1_+_12524965 0.181 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr14_-_57277163 0.179 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr2_+_210444142 0.178 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr17_-_41739283 0.178 ENST00000393661.2
ENST00000318579.4
MEOX1

mesenchyme homeobox 1

chr12_-_28124903 0.177 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chrX_+_99899180 0.177 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr12_-_95510743 0.165 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr18_-_12656715 0.164 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1



spire-type actin nucleation factor 1



chr12_-_123201337 0.160 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr2_+_27440229 0.159 ENST00000264705.4
ENST00000403525.1
CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr11_+_64001962 0.157 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chrX_+_65384052 0.151 ENST00000336279.5
ENST00000458621.1
HEPH

hephaestin

chr14_-_72458326 0.151 ENST00000542853.1
AC005477.1
AC005477.1
chr3_-_20053741 0.142 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr12_+_1800179 0.139 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr20_+_42984330 0.137 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chrX_+_65384182 0.136 ENST00000441993.2
ENST00000419594.1
HEPH

hephaestin

chr19_-_19626838 0.133 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr8_-_21669826 0.132 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chr1_+_62439037 0.131 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_-_12677714 0.130 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr7_-_27205136 0.130 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr11_+_34663913 0.129 ENST00000532302.1
EHF
ets homologous factor
chr11_+_63606373 0.128 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr8_-_18666360 0.126 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_9129598 0.126 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_-_36233332 0.120 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1



IGF-like family receptor 1



chr16_-_2314222 0.118 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr8_+_26150628 0.113 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr2_-_136678123 0.112 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr1_+_26485511 0.109 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr7_-_81399355 0.107 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_+_49715293 0.105 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr7_+_22766766 0.102 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr14_-_57277178 0.100 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2


orthodenticle homeobox 2


chr1_-_9129735 0.100 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr15_+_69854027 0.096 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr6_-_41703952 0.092 ENST00000358871.2
ENST00000403298.4
TFEB

transcription factor EB

chr11_-_5537920 0.089 ENST00000380184.1
UBQLNL
ubiquilin-like
chr6_+_15246501 0.089 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr1_+_52682052 0.087 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr22_-_30642782 0.087 ENST00000249075.3
LIF
leukemia inhibitory factor
chr1_+_66999268 0.083 ENST00000371039.1
ENST00000424320.1
SGIP1

SH3-domain GRB2-like (endophilin) interacting protein 1

chr19_-_45927622 0.082 ENST00000300853.3
ENST00000589165.1
ERCC1

excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

chr1_+_46152886 0.078 ENST00000372025.4
TMEM69
transmembrane protein 69
chr12_-_18243075 0.077 ENST00000536890.1
RERGL
RERG/RAS-like
chr9_+_82188077 0.077 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_48351743 0.076 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO


maestro


chr6_-_64029879 0.076 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr18_+_61223393 0.076 ENST00000269491.1
ENST00000382768.1
SERPINB12

serpin peptidase inhibitor, clade B (ovalbumin), member 12

chr3_-_71294304 0.076 ENST00000498215.1
FOXP1
forkhead box P1
chr1_+_229440129 0.074 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr9_+_105757590 0.074 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr1_-_9129631 0.073 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr9_+_82187630 0.068 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_+_36887069 0.066 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41


chromosome 15 open reading frame 41


chr18_+_29769978 0.066 ENST00000269202.6
ENST00000581447.1
MEP1B

meprin A, beta

chr9_+_82187487 0.065 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chr11_-_102576537 0.061 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr1_-_242162375 0.061 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr17_-_79876010 0.061 ENST00000328666.6
SIRT7
sirtuin 7
chrX_+_65382381 0.058 ENST00000519389.1
HEPH
hephaestin
chr7_-_122840015 0.056 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr19_+_35634146 0.056 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7


FXYD domain containing ion transport regulator 7


chr7_-_27169801 0.055 ENST00000511914.1
HOXA4
homeobox A4
chr17_-_46690839 0.055 ENST00000498634.2
HOXB8
homeobox B8
chr20_-_56285595 0.053 ENST00000395816.3
ENST00000347215.4
PMEPA1

prostate transmembrane protein, androgen induced 1

chr6_-_137815524 0.052 ENST00000367734.2
OLIG3
oligodendrocyte transcription factor 3
chr2_-_207023918 0.051 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1


NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)


chr22_+_41697520 0.051 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr1_-_200379180 0.050 ENST00000294740.3
ZNF281
zinc finger protein 281
chr6_+_132873832 0.048 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr20_+_4702548 0.048 ENST00000305817.2
PRND
prion protein 2 (dublet)
chr2_+_176987088 0.048 ENST00000249499.6
HOXD9
homeobox D9
chr3_+_15045419 0.047 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr11_+_34664014 0.046 ENST00000527935.1
EHF
ets homologous factor
chr2_-_50574856 0.045 ENST00000342183.5
NRXN1
neurexin 1
chr3_+_16306837 0.044 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr5_+_145718587 0.043 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr12_-_18243119 0.043 ENST00000538724.1
ENST00000229002.2
RERGL

RERG/RAS-like

chr3_+_89156674 0.042 ENST00000336596.2
EPHA3
EPH receptor A3
chr2_+_208423891 0.041 ENST00000448277.1
ENST00000457101.1
CREB1

cAMP responsive element binding protein 1

chr11_-_132813566 0.039 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr1_-_113160826 0.039 ENST00000538187.1
ENST00000369664.1
ST7L

suppression of tumorigenicity 7 like

chr14_-_51027838 0.038 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_-_200379129 0.037 ENST00000367353.1
ZNF281
zinc finger protein 281
chr12_+_70219052 0.037 ENST00000552032.2
ENST00000547771.2
MYRFL

myelin regulatory factor-like

chr7_-_81399438 0.036 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_+_95736758 0.035 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr18_+_63417864 0.031 ENST00000536984.2
CDH7
cadherin 7, type 2
chr5_-_88119580 0.029 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr6_+_26156551 0.028 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr2_-_40739501 0.027 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr13_-_74708372 0.026 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr8_+_104831472 0.024 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chr2_-_166930131 0.023 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr19_-_39924349 0.020 ENST00000602153.1
RPS16
ribosomal protein S16
chr12_-_71148413 0.019 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr10_+_115614370 0.019 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr7_-_151217166 0.018 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr14_-_101295407 0.018 ENST00000596284.1
AL117190.2
AL117190.2
chr6_-_91296737 0.016 ENST00000369332.3
ENST00000369329.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr2_-_176046391 0.015 ENST00000392541.3
ENST00000409194.1
ATP5G3

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)

chr13_-_103719196 0.015 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr10_+_47894023 0.015 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr12_-_54071181 0.014 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr16_+_67906919 0.013 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr22_+_41956767 0.013 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr16_+_16429787 0.012 ENST00000331436.4
ENST00000541593.1
AC138969.4

Protein PKD1P1

chr6_-_91296602 0.011 ENST00000369325.3
ENST00000369327.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr8_-_57123815 0.010 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr2_+_109204909 0.009 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_47219733 0.009 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4


solute carrier family 38, member 4


chr16_-_18466642 0.008 ENST00000541810.1
ENST00000531453.2
RP11-1212A22.4

LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1

chr18_+_3252206 0.003 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr19_-_10420459 0.003 ENST00000403352.1
ENST00000403903.3
ZGLP1

zinc finger, GATA-like protein 1

chr12_-_71148357 0.003 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_151739131 0.003 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr3_+_148545586 0.002 ENST00000282957.4
ENST00000468341.1
CPB1

carboxypeptidase B1 (tissue)

chr3_-_79816965 0.002 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr17_+_7461613 0.002 ENST00000438470.1
ENST00000436057.1
TNFSF13

tumor necrosis factor (ligand) superfamily, member 13

chr7_-_108209897 0.002 ENST00000313516.5
THAP5
THAP domain containing 5
chr3_+_173116225 0.002 ENST00000457714.1
NLGN1
neuroligin 1
chr1_+_23345930 0.000 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chr8_+_70378852 0.000 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr9_-_73736511 0.000 ENST00000377110.3
ENST00000377111.2
TRPM3

transient receptor potential cation channel, subfamily M, member 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 1.0 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:2000364 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 1.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_ALK1_PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR