Motif ID: HOXC10_HOXD13

Z-value: 1.219

Transcription factors associated with HOXC10_HOXD13:

Gene SymbolEntrez IDGene Name
HOXC10 ENSG00000180818.4 HOXC10
HOXD13 ENSG00000128714.5 HOXD13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD13hg19_v2_chr2_+_176957619_1769576190.843.4e-07Click!
HOXC10hg19_v2_chr12_+_54378923_54378970-0.232.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC10_HOXD13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_216300784 7.100 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr12_-_52779433 6.808 ENST00000257951.3
KRT84
keratin 84
chr5_+_7654057 6.499 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr1_+_84630645 5.408 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_116654376 4.675 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr2_-_190044480 4.488 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr1_-_152386732 4.329 ENST00000271835.3
CRNN
cornulin
chr20_+_37554955 3.500 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr7_+_134464376 3.460 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr2_-_216878305 3.246 ENST00000263268.6
MREG
melanoregulin
chr1_+_152957707 2.944 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr7_+_134464414 2.907 ENST00000361901.2
CALD1
caldesmon 1
chr7_-_41742697 2.821 ENST00000242208.4
INHBA
inhibin, beta A
chr4_-_69111401 2.768 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr17_-_39553844 2.762 ENST00000251645.2
KRT31
keratin 31
chr4_+_69313145 2.744 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr4_+_169013666 2.658 ENST00000359299.3
ANXA10
annexin A10
chr8_-_49834299 2.504 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr9_+_105757590 2.489 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chrX_-_73072534 2.399 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chrX_-_107682702 2.364 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr18_-_12656715 2.361 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1



spire-type actin nucleation factor 1



chr1_+_153003671 2.316 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr4_-_48018580 2.303 ENST00000514170.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr2_+_158114051 2.298 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr17_-_39526052 2.297 ENST00000251646.3
KRT33B
keratin 33B
chr15_-_80263506 2.235 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr1_+_84630053 2.228 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr6_+_34204642 2.201 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr3_-_52090461 2.156 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr14_-_72458326 2.138 ENST00000542853.1
AC005477.1
AC005477.1
chr21_+_39644214 2.104 ENST00000438657.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr4_-_39033963 2.056 ENST00000381938.3
TMEM156
transmembrane protein 156
chr12_-_95510743 2.026 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr7_+_134551583 2.013 ENST00000435928.1
CALD1
caldesmon 1
chr8_+_42873548 1.999 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr1_+_209859510 1.958 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr1_+_62439037 1.944 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr17_-_38859996 1.943 ENST00000264651.2
KRT24
keratin 24
chr8_+_31497271 1.943 ENST00000520407.1
NRG1
neuregulin 1
chr4_-_68749699 1.896 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr4_+_86525299 1.871 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr1_-_205419053 1.845 ENST00000367154.1
LEMD1
LEM domain containing 1
chr9_-_95640218 1.791 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484


zinc finger protein 484


chr1_+_32042105 1.790 ENST00000457433.2
ENST00000441210.2
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr7_+_134576317 1.762 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr1_+_32042131 1.760 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr12_+_130646999 1.681 ENST00000539839.1
ENST00000229030.4
FZD10

frizzled family receptor 10

chr2_+_210444142 1.650 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr21_+_39644305 1.637 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_17559776 1.619 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1


peptidyl arginine deiminase, type I


chr21_-_28217721 1.591 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr20_+_42984330 1.555 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr21_+_39644395 1.551 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644172 1.540 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr18_+_34124507 1.528 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr6_+_12290586 1.525 ENST00000379375.5
EDN1
endothelin 1
chr20_+_62327996 1.498 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr11_-_107729887 1.462 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr7_+_40174565 1.436 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10





succinylCoA:glutarate-CoA transferase





chr6_-_27114577 1.431 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr1_-_9129735 1.406 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_-_91539918 1.385 ENST00000548218.1
DCN
decorin
chr17_-_39140549 1.377 ENST00000377755.4
KRT40
keratin 40
chr3_+_57875738 1.376 ENST00000417128.1
ENST00000438794.1
SLMAP

sarcolemma associated protein

chr11_-_128392085 1.367 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr19_+_35634146 1.354 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7


FXYD domain containing ion transport regulator 7


chr20_+_3776371 1.354 ENST00000245960.5
CDC25B
cell division cycle 25B
chr7_+_80275953 1.325 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36


CD36 molecule (thrombospondin receptor)


chr7_-_50860565 1.322 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr7_+_134576151 1.313 ENST00000393118.2
CALD1
caldesmon 1
chr2_-_208031943 1.281 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr20_+_58179582 1.278 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr18_-_5396271 1.268 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr6_-_27775694 1.265 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr19_+_1440838 1.248 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr13_-_103719196 1.241 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr17_+_7211656 1.214 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr7_+_80275752 1.213 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr12_-_30887948 1.207 ENST00000433722.2
CAPRIN2
caprin family member 2
chr1_-_155880672 1.207 ENST00000609492.1
ENST00000368322.3
RIT1

Ras-like without CAAX 1

chr12_+_93096619 1.206 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr11_+_63606373 1.202 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr15_+_67418047 1.199 ENST00000540846.2
SMAD3
SMAD family member 3
chr1_+_52682052 1.188 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr1_-_9129631 1.166 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr8_+_52730143 1.156 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr2_+_210444748 1.147 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr16_+_55600580 1.140 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr1_-_237167718 1.133 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr11_-_7961141 1.126 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr14_-_51027838 1.122 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr11_+_69924639 1.112 ENST00000538023.1
ENST00000398543.2
ANO1

anoctamin 1, calcium activated chloride channel

chr4_-_68749745 1.110 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr8_-_125486755 1.109 ENST00000499418.2
ENST00000530778.1
RNF139-AS1

RNF139 antisense RNA 1 (head to head)

chr7_+_80275621 1.094 ENST00000426978.1
ENST00000432207.1
CD36

CD36 molecule (thrombospondin receptor)

chr21_-_31859755 1.093 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr9_+_125133315 1.092 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr12_+_93096759 1.072 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr10_-_24770632 1.065 ENST00000596413.1
AL353583.1
AL353583.1
chr18_+_61445007 1.059 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr12_-_8814669 1.055 ENST00000535411.1
ENST00000540087.1
MFAP5

microfibrillar associated protein 5

chr3_+_57882024 1.032 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr1_-_43919573 1.029 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
HYI


hydroxypyruvate isomerase (putative)


chr17_-_39646116 1.023 ENST00000328119.6
KRT36
keratin 36
chr7_+_1727755 1.018 ENST00000424383.2
ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr1_-_43919346 0.982 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
HYI



hydroxypyruvate isomerase (putative)



chr16_-_80926457 0.980 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1

RP11-314O13.1

chr15_-_75017711 0.976 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr15_+_41549105 0.967 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr7_-_76255444 0.961 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr17_-_39538550 0.945 ENST00000394001.1
KRT34
keratin 34
chr20_+_16729003 0.938 ENST00000246081.2
OTOR
otoraplin
chr4_+_48018781 0.921 ENST00000295461.5
NIPAL1
NIPA-like domain containing 1
chr2_+_33359687 0.915 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr5_+_39105358 0.915 ENST00000593965.1
AC008964.1
AC008964.1
chr2_-_165424973 0.914 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chrX_+_99899180 0.903 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr12_-_18243119 0.893 ENST00000538724.1
ENST00000229002.2
RERGL

RERG/RAS-like

chr15_-_55541227 0.890 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr19_+_48497962 0.886 ENST00000596043.1
ENST00000597519.1
ELSPBP1

epididymal sperm binding protein 1

chr12_-_52715179 0.886 ENST00000293670.3
KRT83
keratin 83
chr11_-_5537920 0.873 ENST00000380184.1
UBQLNL
ubiquilin-like
chr2_+_33359646 0.860 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr17_-_53809473 0.855 ENST00000575734.1
TMEM100
transmembrane protein 100
chr22_-_50524298 0.850 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_-_39507064 0.850 ENST00000007735.3
KRT33A
keratin 33A
chr5_+_135496675 0.846 ENST00000507637.1
SMAD5
SMAD family member 5
chr2_-_238322800 0.844 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr19_+_48497901 0.844 ENST00000339841.2
ELSPBP1
epididymal sperm binding protein 1
chr2_+_101591314 0.839 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr7_-_36634181 0.838 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr11_-_2158507 0.827 ENST00000381392.1
ENST00000381395.1
ENST00000418738.2
IGF2


insulin-like growth factor 2 (somatomedin A)


chr11_-_19082216 0.812 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr18_+_21032781 0.808 ENST00000339486.3
RIOK3
RIO kinase 3
chr4_+_54966198 0.800 ENST00000326902.2
ENST00000503800.1
GSX2

GS homeobox 2

chr1_+_74701062 0.799 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr9_+_75229616 0.794 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr9_+_125132803 0.791 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_111888474 0.788 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr1_+_192127578 0.784 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr1_-_9129598 0.780 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr14_-_107170409 0.770 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr17_-_39637392 0.760 ENST00000246639.2
ENST00000393989.1
KRT35

keratin 35

chr7_+_134430212 0.751 ENST00000436461.2
CALD1
caldesmon 1
chr9_+_131084846 0.747 ENST00000608951.1
COQ4
coenzyme Q4
chr17_+_61086917 0.736 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chrX_+_65382433 0.734 ENST00000374727.3
HEPH
hephaestin
chr8_-_60031762 0.732 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr9_-_21305312 0.728 ENST00000259555.4
IFNA5
interferon, alpha 5
chr6_+_53948328 0.722 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr12_-_95044309 0.706 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr7_+_141490017 0.702 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr17_+_17082842 0.694 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr7_-_92747269 0.694 ENST00000446617.1
ENST00000379958.2
SAMD9

sterile alpha motif domain containing 9

chr19_-_10420459 0.687 ENST00000403352.1
ENST00000403903.3
ZGLP1

zinc finger, GATA-like protein 1

chr15_-_89764929 0.686 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr6_+_42584847 0.679 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr12_-_117799446 0.678 ENST00000317775.6
ENST00000344089.3
NOS1

nitric oxide synthase 1 (neuronal)

chr2_-_238323007 0.673 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chrX_+_65384052 0.672 ENST00000336279.5
ENST00000458621.1
HEPH

hephaestin

chr3_-_51813009 0.668 ENST00000398780.3
IQCF6
IQ motif containing F6
chr3_+_160394940 0.652 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr6_-_100442077 0.651 ENST00000281806.2
ENST00000369212.2
MCHR2

melanin-concentrating hormone receptor 2

chr7_-_27205136 0.648 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr11_+_64001962 0.639 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr14_+_73706308 0.635 ENST00000554301.1
ENST00000555445.1
PAPLN

papilin, proteoglycan-like sulfated glycoprotein

chr12_+_71833756 0.631 ENST00000536515.1
ENST00000540815.2
LGR5

leucine-rich repeat containing G protein-coupled receptor 5

chr4_+_71248795 0.629 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr13_+_46039037 0.626 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr8_+_128426535 0.621 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr1_+_192544857 0.619 ENST00000367459.3
ENST00000469578.2
RGS1

regulator of G-protein signaling 1

chr12_-_91576561 0.618 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr21_+_17792672 0.617 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_108145499 0.615 ENST00000369020.3
ENST00000369022.2
SCML4

sex comb on midleg-like 4 (Drosophila)

chr16_+_86612112 0.613 ENST00000320241.3
FOXL1
forkhead box L1
chr10_+_90354503 0.611 ENST00000531458.1
LIPJ
lipase, family member J
chr19_+_10397648 0.609 ENST00000340992.4
ENST00000393717.2
ICAM4

intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)

chr13_+_109248500 0.601 ENST00000356711.2
MYO16
myosin XVI
chr5_+_95997769 0.596 ENST00000338252.3
ENST00000508830.1
CAST

calpastatin

chr13_-_24007815 0.583 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr2_+_105050794 0.582 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2


long intergenic non-protein coding RNA 1102


chr17_-_62340581 0.581 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2


testis expressed 2


chr6_-_10415470 0.576 ENST00000379604.2
ENST00000379613.3
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr3_-_37216055 0.572 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr1_-_242162375 0.566 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr20_-_50722183 0.561 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr7_-_48068671 0.559 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chrM_-_14670 0.558 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr6_+_130339710 0.556 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr8_+_77593448 0.554 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr3_+_101546827 0.554 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr9_+_36572851 0.553 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr16_+_2285817 0.553 ENST00000564065.1
DNASE1L2
deoxyribonuclease I-like 2
chr15_+_40886199 0.550 ENST00000346991.5
ENST00000528975.1
ENST00000527044.1
CASC5


cancer susceptibility candidate 5


chr9_+_82187487 0.548 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chr4_-_52883786 0.548 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr1_-_42384343 0.547 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr2_+_183580954 0.544 ENST00000264065.7
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr7_-_142139783 0.544 ENST00000390374.3
TRBV7-6
T cell receptor beta variable 7-6

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.5 4.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.1 7.7 GO:0097338 response to clozapine(GO:0097338)
0.9 2.8 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.8 2.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 3.6 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 1.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 6.5 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.5 6.8 GO:0035878 nail development(GO:0035878)
0.5 3.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 2.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.4 2.7 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.3 2.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 2.4 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.3 1.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.3 1.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 1.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 2.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.2 1.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.7 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 1.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.8 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 1.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 0.6 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 1.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.5 GO:0003358 noradrenergic neuron development(GO:0003358)
0.2 1.4 GO:0030578 PML body organization(GO:0030578)
0.2 0.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 1.0 GO:0035803 egg coat formation(GO:0035803)
0.2 1.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.5 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:0003404 optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409)
0.1 0.8 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 2.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:0003335 corneocyte development(GO:0003335)
0.1 2.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 18.6 GO:0070268 cornification(GO:0070268)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 1.4 GO:0007144 female meiosis I(GO:0007144)
0.1 0.6 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 6.1 GO:0010107 potassium ion import(GO:0010107)
0.1 1.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.9 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.4 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.4 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.5 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.1 1.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 2.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 3.3 GO:0032402 melanosome transport(GO:0032402)
0.1 1.6 GO:0060347 heart trabecula formation(GO:0060347)
0.1 1.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 1.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 0.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 1.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.3 GO:1990523 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.1 0.6 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.3 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.2 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.1 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 3.3 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.1 0.2 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.7 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 1.7 GO:0048240 sperm capacitation(GO:0048240)
0.1 2.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0051775 response to redox state(GO:0051775)
0.1 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.5 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.2 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0046098 guanine metabolic process(GO:0046098) response to fungicide(GO:0060992)
0.0 0.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.7 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) tricuspid valve morphogenesis(GO:0003186)
0.0 0.1 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.9 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 1.3 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.4 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:2000342 ERK5 cascade(GO:0070375) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.7 GO:0007635 chemosensory behavior(GO:0007635)
0.0 2.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.8 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.6 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.8 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 2.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 1.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:2000172 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.1 GO:0035990 tendon development(GO:0035989) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.5 GO:0006826 iron ion transport(GO:0006826)
0.0 0.2 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.3 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.7 GO:0048599 oocyte development(GO:0048599)
0.0 8.4 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 1.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 2.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 1.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.3 GO:1901661 quinone metabolic process(GO:1901661)
0.0 1.0 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.4 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 1.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.3 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.4 GO:0016197 endosomal transport(GO:0016197)
0.0 0.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:1904262 TORC2 signaling(GO:0038203) negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.6 GO:0009408 response to heat(GO:0009408)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0005588 collagen type V trimer(GO:0005588)
0.9 2.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.8 2.5 GO:0033150 cytoskeletal calyx(GO:0033150)
0.8 12.2 GO:0030478 actin cap(GO:0030478)
0.7 2.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 7.3 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 7.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 2.0 GO:0070695 FHF complex(GO:0070695)
0.3 3.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.0 GO:0031417 NatC complex(GO:0031417)
0.2 6.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 0.7 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.2 1.2 GO:0097427 microtubule bundle(GO:0097427)
0.2 0.5 GO:0000806 Y chromosome(GO:0000806)
0.2 3.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.2 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.7 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 2.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 2.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 19.9 GO:0005882 intermediate filament(GO:0005882)
0.1 1.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 3.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.7 GO:0030673 axolemma(GO:0030673)
0.1 4.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 2.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 3.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 3.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 3.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 1.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0009986 cell surface(GO:0009986)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.5 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.7 11.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 2.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.6 3.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 1.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 7.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 0.8 GO:0031013 troponin I binding(GO:0031013)
0.4 2.7 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.4 6.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 6.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 11.8 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.8 GO:0050436 microfibril binding(GO:0050436)
0.3 1.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 1.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 0.8 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 1.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 1.5 GO:0004882 androgen receptor activity(GO:0004882)
0.2 2.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 1.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 2.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 2.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 2.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.9 GO:0051400 BH domain binding(GO:0051400)
0.1 7.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 2.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 4.0 GO:0043236 laminin binding(GO:0043236)
0.1 0.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.8 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.6 GO:0030492 hemoglobin binding(GO:0030492)
0.1 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.8 GO:0089720 caspase binding(GO:0089720)
0.1 6.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.9 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 3.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 2.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.8 GO:0042923 neuropeptide binding(GO:0042923)
0.0 2.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 1.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 4.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 3.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0015085 calcium ion transmembrane transporter activity(GO:0015085)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 3.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0044736 hydrogen ion channel activity(GO:0015252) acid-sensing ion channel activity(GO:0044736)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 14.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 6.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 7.8 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 7.9 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.8 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 2.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 4.4 PID_LKB1_PATHWAY LKB1 signaling events
0.1 4.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 3.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 2.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 12.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 2.5 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 2.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.0 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.3 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.7 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.2 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.2 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 1.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.3 7.7 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 2.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 7.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 12.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 7.0 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 2.7 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 7.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 2.6 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 2.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.2 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 3.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.0 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.1 1.4 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.0 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.7 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 5.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.0 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 2.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 2.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors