Motif ID: HOXB6_PRRX2

Z-value: 0.905

Transcription factors associated with HOXB6_PRRX2:

Gene SymbolEntrez IDGene Name
HOXB6 ENSG00000108511.8 HOXB6
PRRX2 ENSG00000167157.9 PRRX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRRX2hg19_v2_chr9_+_132427883_132427951-0.232.8e-01Click!
HOXB6hg19_v2_chr17_-_46682321_466823620.067.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_135251783 2.611 ENST00000394153.2
FHL1
four and a half LIM domains 1
chrX_+_135252050 2.423 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chrX_+_135251835 2.353 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr1_+_50569575 2.160 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chrX_+_135279179 2.097 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr2_-_161056762 1.949 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr5_-_88119580 1.929 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr12_-_122240792 1.844 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr12_-_89746173 1.836 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr2_-_216257849 1.728 ENST00000456923.1
FN1
fibronectin 1
chr12_+_4385230 1.722 ENST00000536537.1
CCND2
cyclin D2
chr2_+_54785485 1.686 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_-_39211463 1.496 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr7_-_41742697 1.449 ENST00000242208.4
INHBA
inhibin, beta A
chr6_+_130339710 1.405 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chrX_+_135278908 1.403 ENST00000539015.1
ENST00000370683.1
FHL1

four and a half LIM domains 1

chr4_-_41750922 1.363 ENST00000226382.2
PHOX2B
paired-like homeobox 2b
chr3_-_74570291 1.342 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr14_-_57272366 1.292 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2


orthodenticle homeobox 2


chr2_+_191792376 1.236 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr16_+_8806800 1.145 ENST00000561870.1
ENST00000396600.2
ABAT

4-aminobutyrate aminotransferase

chr4_+_169013666 1.140 ENST00000359299.3
ANXA10
annexin A10
chr2_-_161056802 1.134 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr1_+_84630053 1.116 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr2_-_216003127 1.114 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr2_-_208030647 1.108 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_+_210444748 1.096 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr2_-_50201327 1.092 ENST00000412315.1
NRXN1
neurexin 1
chr13_-_36050819 1.069 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr1_+_50574585 1.068 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr12_-_12674032 1.061 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr2_+_210444142 1.037 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr8_-_95449155 1.009 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr3_+_141106458 0.997 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr20_-_7921090 0.983 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr1_-_205391178 0.974 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr2_+_102508955 0.942 ENST00000414004.2
FLJ20373
FLJ20373
chr3_+_141105705 0.933 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_-_83824169 0.933 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr14_+_22977587 0.930 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr7_-_14026123 0.920 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1


ets variant 1


chr3_+_130569592 0.905 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr4_+_71494461 0.905 ENST00000396073.3
ENAM
enamelin
chr1_+_84630645 0.901 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_39140549 0.899 ENST00000377755.4
KRT40
keratin 40
chr10_+_11047259 0.884 ENST00000379261.4
ENST00000416382.2
CELF2

CUGBP, Elav-like family member 2

chr3_+_111718173 0.870 ENST00000494932.1
TAGLN3
transgelin 3
chr7_-_107642348 0.865 ENST00000393561.1
LAMB1
laminin, beta 1
chr11_-_84634217 0.863 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr10_+_118187379 0.862 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr13_+_96085847 0.850 ENST00000376873.3
CLDN10
claudin 10
chr12_-_28124903 0.849 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr14_-_95236551 0.843 ENST00000238558.3
GSC
goosecoid homeobox
chr7_+_134464376 0.839 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr3_+_111717600 0.839 ENST00000273368.4
TAGLN3
transgelin 3
chr8_+_42873548 0.817 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr3_-_57233966 0.803 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr15_-_56209306 0.800 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr7_+_123241908 0.776 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15


ankyrin repeat and SOCS box containing 15


chr6_-_66417107 0.772 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr10_+_94833642 0.771 ENST00000224356.4
ENST00000394139.1
CYP26A1

cytochrome P450, family 26, subfamily A, polypeptide 1

chrX_+_28605516 0.761 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr3_-_196911002 0.758 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_+_134576151 0.758 ENST00000393118.2
CALD1
caldesmon 1
chr7_+_107110488 0.757 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr6_-_108145499 0.752 ENST00000369020.3
ENST00000369022.2
SCML4

sex comb on midleg-like 4 (Drosophila)

chrX_-_15683147 0.748 ENST00000380342.3
TMEM27
transmembrane protein 27
chr8_-_122653630 0.741 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr12_-_28125638 0.740 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr15_+_93443419 0.732 ENST00000557381.1
ENST00000420239.2
CHD2

chromodomain helicase DNA binding protein 2

chr2_-_208031943 0.725 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr7_-_27183263 0.724 ENST00000222726.3
HOXA5
homeobox A5
chr3_+_111717511 0.723 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr11_+_124735282 0.718 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr1_+_186265399 0.717 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr11_-_125366089 0.715 ENST00000366139.3
ENST00000278919.3
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr15_-_70390191 0.713 ENST00000559191.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr1_+_107683436 0.705 ENST00000370068.1
NTNG1
netrin G1
chr13_-_46716969 0.694 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr10_-_33623310 0.691 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1



neuropilin 1



chr20_-_50419055 0.690 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr18_-_31628558 0.689 ENST00000535384.1
NOL4
nucleolar protein 4
chr2_+_28618532 0.686 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr1_-_203055129 0.683 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr3_+_111718036 0.673 ENST00000455401.2
TAGLN3
transgelin 3
chr17_-_39203519 0.672 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr2_-_29297127 0.672 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr9_-_128246769 0.672 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr2_+_177015950 0.667 ENST00000306324.3
HOXD4
homeobox D4
chr7_+_139529040 0.654 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1


thromboxane A synthase 1 (platelet)


chr17_-_38859996 0.636 ENST00000264651.2
KRT24
keratin 24
chr3_+_137490748 0.634 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr2_+_182850743 0.629 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_-_28122980 0.624 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr7_+_134576317 0.623 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr4_-_68749745 0.620 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr8_+_85618155 0.617 ENST00000523850.1
ENST00000521376.1
RALYL

RALY RNA binding protein-like

chr17_-_57229155 0.616 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr4_-_68749699 0.609 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr7_+_28452130 0.609 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr13_-_103719196 0.608 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr9_+_75263565 0.606 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr17_-_9694614 0.602 ENST00000330255.5
ENST00000571134.1
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr21_-_40033618 0.595 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG


v-ets avian erythroblastosis virus E26 oncogene homolog


chr7_-_27205136 0.594 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr3_-_185826855 0.593 ENST00000306376.5
ETV5
ets variant 5
chr12_-_86650045 0.591 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_-_163695128 0.590 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr6_+_50681541 0.589 ENST00000008391.3
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr3_-_141747950 0.584 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_+_17270214 0.580 ENST00000544301.1
VIM
vimentin
chr8_-_133123406 0.579 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr11_-_107729887 0.576 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr1_+_107682629 0.575 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1






netrin G1






chr3_-_196910721 0.571 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr5_-_112630598 0.569 ENST00000302475.4
MCC
mutated in colorectal cancers
chr2_+_33359687 0.568 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr11_+_131240373 0.565 ENST00000374791.3
ENST00000436745.1
NTM

neurotrimin

chr14_-_57277163 0.564 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr2_+_33359646 0.564 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr9_+_12693336 0.562 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr7_+_134464414 0.559 ENST00000361901.2
CALD1
caldesmon 1
chr18_-_31803169 0.555 ENST00000590712.1
NOL4
nucleolar protein 4
chr7_+_139528952 0.551 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1



thromboxane A synthase 1 (platelet)



chr4_+_41258786 0.546 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1



ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)



chr12_-_91576750 0.544 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN


decorin


chr4_-_143227088 0.544 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr11_-_128457446 0.542 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr6_+_12290586 0.541 ENST00000379375.5
EDN1
endothelin 1
chr3_+_141105235 0.540 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_53994805 0.534 ENST00000328463.7
ATF7
activating transcription factor 7
chr2_-_69098566 0.533 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr7_-_80141328 0.529 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr16_+_7382745 0.521 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1



RNA binding protein, fox-1 homolog (C. elegans) 1



chr1_+_205682497 0.518 ENST00000598338.1
AC119673.1
AC119673.1
chr18_+_47088401 0.512 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr8_+_54764346 0.507 ENST00000297313.3
ENST00000344277.6
RGS20

regulator of G-protein signaling 20

chr1_-_94079648 0.505 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr2_-_214013353 0.502 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2



IKAROS family zinc finger 2 (Helios)



chr12_-_28123206 0.502 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr7_-_37026108 0.501 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr18_+_29027696 0.498 ENST00000257189.4
DSG3
desmoglein 3
chr5_-_179045199 0.498 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr10_-_49813090 0.498 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr2_-_214016314 0.495 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr11_+_128562372 0.494 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_131321863 0.489 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr12_-_25055177 0.487 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr3_-_4793274 0.482 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr16_+_72459838 0.481 ENST00000564508.1
AC004158.3
AC004158.3
chr11_-_84634447 0.481 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_113897899 0.480 ENST00000383673.2
ENST00000295881.7
DRD3

dopamine receptor D3

chr11_-_83393457 0.478 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_86650077 0.476 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr4_+_71200681 0.475 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr2_+_182850551 0.473 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr5_+_31193847 0.473 ENST00000514738.1
ENST00000265071.2
CDH6

cadherin 6, type 2, K-cadherin (fetal kidney)

chr1_+_168250194 0.470 ENST00000367821.3
TBX19
T-box 19
chr1_-_197036364 0.470 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr1_+_65730385 0.469 ENST00000263441.7
ENST00000395325.3
DNAJC6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr19_-_50143452 0.465 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr10_+_11206925 0.463 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr12_-_91576561 0.463 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr10_-_105845674 0.461 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr9_+_132099158 0.459 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr18_+_21529811 0.458 ENST00000588004.1
LAMA3
laminin, alpha 3
chr20_+_58630972 0.456 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr7_+_18535346 0.453 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9


histone deacetylase 9


chr3_+_158787041 0.452 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr2_-_2334888 0.451 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr2_-_100987007 0.451 ENST00000595083.1
AC012493.2
Uncharacterized protein
chr20_-_10654639 0.448 ENST00000254958.5
JAG1
jagged 1
chr5_+_66300446 0.448 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr5_+_145718587 0.443 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr1_+_62439037 0.442 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr3_+_130569429 0.442 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr2_-_177502659 0.441 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr2_-_190927447 0.439 ENST00000260950.4
MSTN
myostatin
chr12_-_91398796 0.438 ENST00000261172.3
ENST00000551767.1
EPYC

epiphycan

chr10_+_118083919 0.436 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr6_-_10412600 0.434 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_-_49124230 0.431 ENST00000510283.1
ENST00000510855.1
SPAG9

sperm associated antigen 9

chr2_-_119605253 0.429 ENST00000295206.6
EN1
engrailed homeobox 1
chr13_-_99667960 0.425 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr3_-_190167571 0.423 ENST00000354905.2
TMEM207
transmembrane protein 207
chr18_+_56530136 0.421 ENST00000591083.1
ZNF532
zinc finger protein 532
chr11_-_83984231 0.421 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
DLG2




discs, large homolog 2 (Drosophila)




chr5_-_24645078 0.421 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chrX_-_45629661 0.420 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2

RP6-99M1.2

chr3_+_111630451 0.417 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_-_30887948 0.416 ENST00000433722.2
CAPRIN2
caprin family member 2
chr8_-_91095099 0.415 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr8_+_77593448 0.414 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr18_-_44181442 0.413 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr8_-_131399110 0.413 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_+_77333117 0.410 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr2_+_54683419 0.410 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_-_39274606 0.408 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr3_-_123339343 0.408 ENST00000578202.1
MYLK
myosin light chain kinase
chr7_-_112727774 0.407 ENST00000297146.3
ENST00000501255.2
GPR85

G protein-coupled receptor 85


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.6 1.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 2.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.5 2.0 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.5 1.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 1.4 GO:0003358 noradrenergic neuron development(GO:0003358)
0.3 1.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.3 3.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.3 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.3 0.6 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.3 0.9 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 1.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 0.8 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.3 1.1 GO:0035627 ceramide transport(GO:0035627)
0.3 1.6 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 1.1 GO:0003409 optic cup structural organization(GO:0003409)
0.3 1.9 GO:0097338 response to clozapine(GO:0097338)
0.3 2.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 1.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.7 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.7 GO:0060435 bronchiole development(GO:0060435)
0.2 0.7 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.2 1.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.2 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.2 0.8 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 0.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 0.8 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.2 13.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 1.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 1.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.1 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0030035 microspike assembly(GO:0030035)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.4 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 1.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.4 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.2 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.1 0.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 1.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.2 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.1 3.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.3 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.3 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.3 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.3 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.7 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.5 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.8 GO:0030916 otic vesicle formation(GO:0030916)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.4 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.5 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 0.2 GO:0061053 somite development(GO:0061053)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.3 GO:1990523 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0030578 PML body organization(GO:0030578)
0.1 1.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 1.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 2.2 GO:0002076 osteoblast development(GO:0002076)
0.1 0.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.6 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:0003285 septum secundum development(GO:0003285)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.1 GO:1903781 positive regulation of cardiac conduction(GO:1903781)
0.1 0.3 GO:1990834 response to odorant(GO:1990834)
0.1 0.3 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0038027 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119) regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.9 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 4.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.6 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.6 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0071472 cellular response to salt stress(GO:0071472)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0008050 courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.5 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.6 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.4 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.4 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 1.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.2 GO:0060047 heart process(GO:0003015) heart contraction(GO:0060047)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.0 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.3 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.0 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.0 GO:1901629 regulation of presynaptic membrane organization(GO:1901629) regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 2.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0060973 cell migration involved in heart development(GO:0060973)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.3 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.0 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.0 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.5 2.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 1.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 2.1 GO:0032437 cuticular plate(GO:0032437)
0.3 0.9 GO:0005607 laminin-2 complex(GO:0005607)
0.3 1.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 2.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.8 GO:0030478 actin cap(GO:0030478)
0.2 0.5 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 1.3 GO:0043219 lateral loop(GO:0043219)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.7 GO:0097443 sorting endosome(GO:0097443)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.3 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0030133 transport vesicle(GO:0030133)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 2.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 4.3 GO:0072562 blood microparticle(GO:0072562)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 11.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.8 GO:0070161 anchoring junction(GO:0070161)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 1.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 1.7 GO:0050436 microfibril binding(GO:0050436)
0.3 1.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.3 1.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 1.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 1.2 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 2.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.3 GO:0031013 troponin I binding(GO:0031013)
0.2 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.1 GO:0031489 myosin V binding(GO:0031489)
0.1 2.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 2.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 2.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 3.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.5 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0030305 heparanase activity(GO:0030305)
0.1 0.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.6 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 2.9 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 2.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.9 GO:0005549 odorant binding(GO:0005549)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 9.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.6 GO:0031433 telethonin binding(GO:0031433)
0.0 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 2.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 3.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 3.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691) single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.0 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 2.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.9 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 3.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 2.2 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.5 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 2.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 2.3 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 2.7 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.5 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.5 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.3 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.8 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.8 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.1 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.4 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.2 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID_MYC_PATHWAY C-MYC pathway
0.0 1.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 2.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.1 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 2.9 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.1 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.7 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.1 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 4.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 2.2 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 1.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.0 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 1.2 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.5 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.7 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.0 2.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.8 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases