Motif ID: HOXB2_UNCX_HOXD3

Z-value: 0.511

Transcription factors associated with HOXB2_UNCX_HOXD3:

Gene SymbolEntrez IDGene Name
HOXB2 ENSG00000173917.9 HOXB2
HOXD3 ENSG00000128652.7 HOXD3
UNCX ENSG00000164853.8 UNCX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD3hg19_v2_chr2_+_177015122_1770151220.125.7e-01Click!
HOXB2hg19_v2_chr17_-_46623441_46623441-0.029.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_141747950 1.346 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_217804661 0.964 ENST00000366933.4
SPATA17
spermatogenesis associated 17
chr12_+_7013897 0.926 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr12_+_7014064 0.904 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr1_-_47407097 0.884 ENST00000457840.2
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr8_-_10512569 0.873 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr5_+_68860949 0.863 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr20_-_7921090 0.820 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_76072719 0.771 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chrX_-_13835147 0.763 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr8_+_94241867 0.745 ENST00000598428.1
AC016885.1
Uncharacterized protein
chr17_-_39306054 0.724 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5
chr6_-_49681235 0.679 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr16_+_53133070 0.645 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_-_33446735 0.571 ENST00000460118.2
ENST00000335858.7
RAD51D

RAD51 paralog D

chr1_-_48937838 0.567 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr10_-_28270795 0.566 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr4_-_105416039 0.555 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_109256067 0.538 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr9_-_95166884 0.514 ENST00000375561.5
OGN
osteoglycin
chr9_-_5304432 0.497 ENST00000416837.1
ENST00000308420.3
RLN2

relaxin 2

chr11_-_5255861 0.493 ENST00000380299.3
HBD
hemoglobin, delta
chr20_+_31870927 0.490 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr4_-_138453606 0.488 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chrY_+_15016013 0.482 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr6_+_127898312 0.467 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr1_+_118148556 0.454 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr6_-_76203454 0.449 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr14_-_106926724 0.447 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr4_-_168155169 0.446 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr5_-_13944652 0.433 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr13_-_36429763 0.429 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_-_74486109 0.426 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_101360331 0.419 ENST00000416479.1
ENST00000370113.3
EXTL2

exostosin-like glycosyltransferase 2

chr7_+_99717230 0.418 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr10_-_69597915 0.407 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr6_-_15586238 0.404 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr11_+_101918153 0.402 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr1_-_86848760 0.402 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr3_-_112564797 0.400 ENST00000398214.1
ENST00000448932.1
CD200R1L

CD200 receptor 1-like

chr4_-_74486347 0.400 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr22_+_23487513 0.394 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr2_-_216946500 0.394 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr17_-_3030875 0.394 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr2_+_179184955 0.390 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr11_+_60467047 0.388 ENST00000300226.2
MS4A8
membrane-spanning 4-domains, subfamily A, member 8
chr13_+_77522632 0.383 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr5_+_140602904 0.380 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr6_+_43612750 0.378 ENST00000372165.4
ENST00000372163.4
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr21_-_43735628 0.377 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr17_-_39203519 0.367 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr11_-_31531121 0.365 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr4_+_165675197 0.362 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr19_-_55677999 0.359 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr5_-_137475071 0.358 ENST00000265191.2
NME5
NME/NM23 family member 5
chr9_-_95166841 0.356 ENST00000262551.4
OGN
osteoglycin
chr1_+_54359854 0.349 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1





deiodinase, iodothyronine, type I





chr9_+_124922171 0.346 ENST00000373764.3
ENST00000536616.1
MORN5

MORN repeat containing 5

chr4_+_36283213 0.345 ENST00000357504.3
DTHD1
death domain containing 1
chr9_+_108463234 0.344 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr12_+_82347498 0.341 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr12_+_7014126 0.338 ENST00000415834.1
ENST00000436789.1
LRRC23

leucine rich repeat containing 23

chr2_+_228736321 0.337 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr12_-_23737534 0.337 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr2_+_183982238 0.334 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35


nucleoporin 35kDa


chr5_-_150473127 0.334 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr3_+_63638339 0.333 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr16_+_58283814 0.333 ENST00000443128.2
ENST00000219299.4
CCDC113

coiled-coil domain containing 113

chr3_+_108541608 0.331 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr3_+_108541545 0.331 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr1_-_48937821 0.327 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr2_+_109237717 0.327 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_+_165675269 0.326 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr7_-_16921601 0.324 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3


anterior gradient 3


chr7_+_23719749 0.324 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A



family with sequence similarity 221, member A



chr13_+_50589390 0.321 ENST00000360473.4
ENST00000312942.1
KCNRG

potassium channel regulator

chr1_-_150738261 0.320 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr10_-_105110831 0.316 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr4_+_66536248 0.314 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr6_+_153552455 0.314 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr6_-_87804815 0.312 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr15_-_37393406 0.312 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr11_-_118023490 0.312 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr6_-_28411241 0.311 ENST00000289788.4
ZSCAN23
zinc finger and SCAN domain containing 23
chr5_-_35938674 0.310 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr1_+_101003687 0.307 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr21_-_32253874 0.305 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr3_+_149191723 0.304 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr14_+_65016620 0.303 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr10_-_27529486 0.298 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr9_+_100069933 0.295 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chrX_+_36246735 0.293 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chrX_+_105855160 0.289 ENST00000372544.2
ENST00000372548.4
CXorf57

chromosome X open reading frame 57

chr6_-_32157947 0.288 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr6_+_131958436 0.285 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr4_+_169013666 0.285 ENST00000359299.3
ANXA10
annexin A10
chr3_+_140981456 0.284 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr4_+_169418195 0.281 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr1_+_174844645 0.281 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chrX_-_117119243 0.280 ENST00000539496.1
ENST00000469946.1
KLHL13

kelch-like family member 13

chr21_+_31768348 0.280 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr6_-_26235206 0.280 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr6_+_29274403 0.279 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr17_+_42786051 0.276 ENST00000315005.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr4_-_70505358 0.272 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2


UDP glucuronosyltransferase 2 family, polypeptide A2


chr7_-_25268104 0.272 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr6_-_15548591 0.272 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr19_-_55677920 0.269 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr1_+_3607228 0.268 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73


tumor protein p73


chr6_+_88117683 0.267 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr3_-_69129501 0.267 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3



ubiquitin-like modifier activating enzyme 3



chr5_-_146781153 0.267 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr17_+_11501748 0.267 ENST00000262442.4
ENST00000579828.1
DNAH9

dynein, axonemal, heavy chain 9

chr11_+_122753391 0.266 ENST00000307257.6
ENST00000227349.2
C11orf63

chromosome 11 open reading frame 63

chr1_+_109255279 0.265 ENST00000370017.3
FNDC7
fibronectin type III domain containing 7
chr5_-_24645078 0.265 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr17_-_56296580 0.264 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
MKS1



Meckel syndrome, type 1



chr2_+_176994408 0.264 ENST00000429017.1
ENST00000313173.4
ENST00000544999.1
HOXD8


homeobox D8


chr7_-_138386097 0.264 ENST00000421622.1
SVOPL
SVOP-like
chr7_+_77428149 0.263 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr5_+_61874562 0.263 ENST00000409534.1
ENST00000334994.5
IPO11
LRRC70
importin 11
leucine rich repeat containing 70
chr3_-_108248169 0.261 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr1_-_169396666 0.254 ENST00000456107.1
ENST00000367805.3
CCDC181

coiled-coil domain containing 181

chr7_-_130080977 0.254 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr10_+_134150835 0.253 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr10_-_105110890 0.250 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr4_+_71108300 0.250 ENST00000304954.3
CSN3
casein kappa
chr4_-_110723134 0.247 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr5_+_140227048 0.245 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr1_-_54411255 0.244 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr6_-_111804905 0.242 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr17_-_39597173 0.241 ENST00000246646.3
KRT38
keratin 38
chr2_+_179318295 0.241 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr12_+_20963647 0.240 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr6_+_132873832 0.239 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr2_-_28113965 0.238 ENST00000302188.3
RBKS
ribokinase
chr11_-_111944704 0.238 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr12_+_113587558 0.236 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr15_-_31393910 0.235 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr19_-_46088068 0.234 ENST00000263275.4
ENST00000323060.3
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr3_+_130745688 0.233 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11





NIMA-related kinase 11





chr12_+_20963632 0.232 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr8_+_101170563 0.232 ENST00000520508.1
ENST00000388798.2
SPAG1

sperm associated antigen 1

chr6_-_139613269 0.232 ENST00000358430.3
TXLNB
taxilin beta
chr15_-_65903407 0.231 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9





von Willebrand factor A domain containing 9





chr2_+_109204743 0.231 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_-_52705641 0.230 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr10_+_115511213 0.229 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr22_+_18632666 0.228 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr18_-_71815051 0.227 ENST00000582526.1
ENST00000419743.2
FBXO15

F-box protein 15

chr11_-_47736896 0.226 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2




ATP/GTP binding protein-like 2




chr4_+_56815102 0.226 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr18_+_32173276 0.224 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr4_+_159727272 0.223 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr9_+_26956371 0.221 ENST00000380062.5
ENST00000518614.1
IFT74

intraflagellar transport 74 homolog (Chlamydomonas)

chr4_-_177116772 0.221 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr4_+_169418255 0.221 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr3_-_126327398 0.217 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr11_-_102668879 0.216 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr14_+_74111578 0.216 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr4_-_89951028 0.214 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr1_+_236958554 0.214 ENST00000366577.5
ENST00000418145.2
MTR

5-methyltetrahydrofolate-homocysteine methyltransferase

chr1_-_232651312 0.213 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr17_+_48823975 0.212 ENST00000513969.1
ENST00000503728.1
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr11_+_101785727 0.212 ENST00000263468.8
KIAA1377
KIAA1377
chr16_-_21289627 0.210 ENST00000396023.2
ENST00000415987.2
CRYM

crystallin, mu

chr1_-_149900122 0.210 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr21_+_42694732 0.208 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr1_+_153940346 0.208 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
CREB3L4



cAMP responsive element binding protein 3-like 4



chr12_+_111051902 0.207 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1



tectonic family member 1



chr12_-_39734783 0.206 ENST00000552961.1
KIF21A
kinesin family member 21A
chr17_+_9479944 0.205 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr3_+_111393501 0.204 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_-_165723088 0.204 ENST00000230301.8
C6orf118
chromosome 6 open reading frame 118
chr8_+_38831683 0.204 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr7_+_77428066 0.204 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr10_+_35484793 0.203 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr3_-_33686925 0.203 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr7_-_99527243 0.202 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr18_-_61311485 0.201 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4


serpin peptidase inhibitor, clade B (ovalbumin), member 4


chr3_-_112693865 0.201 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1


CD200 receptor 1


chr8_-_90996459 0.201 ENST00000517337.1
ENST00000409330.1
NBN

nibrin

chr20_+_25388293 0.200 ENST00000262460.4
ENST00000429262.2
GINS1

GINS complex subunit 1 (Psf1 homolog)

chr9_+_36572851 0.200 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr4_+_72204755 0.199 ENST00000512686.1
ENST00000340595.3
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr12_+_111051832 0.199 ENST00000550703.2
ENST00000551590.1
TCTN1

tectonic family member 1

chr8_-_133637624 0.198 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr12_+_41831485 0.196 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chrX_-_24690771 0.196 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr8_-_27468842 0.195 ENST00000523500.1
CLU
clusterin
chr14_-_75530693 0.195 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1




acylphosphatase 1, erythrocyte (common) type




chr1_+_36549676 0.194 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr2_+_169757750 0.192 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2


glucose-6-phosphatase, catalytic, 2


chr13_+_24144509 0.192 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr6_-_46293378 0.192 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr4_+_129730839 0.191 ENST00000511647.1
PHF17
jade family PHD finger 1
chr13_-_61989655 0.190 ENST00000409204.4
PCDH20
protocadherin 20
chr16_-_28634874 0.189 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr9_+_89563578 0.188 ENST00000415801.1
RP11-276H19.1
RP11-276H19.1
chr1_+_104159999 0.187 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0003095 pressure natriuresis(GO:0003095)
0.1 1.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.3 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.1 GO:1901652 response to peptide(GO:1901652)
0.1 2.4 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.3 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.9 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0042100 B cell proliferation(GO:0042100)
0.0 1.5 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.0 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.0 0.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 1.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.2 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.0 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0090298 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.3 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027) AV node cell to bundle of His cell communication(GO:0086067)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.0 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.2 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:2000819 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) regulation of nucleotide-excision repair(GO:2000819)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0048170 striatal medium spiny neuron differentiation(GO:0021773) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.9 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.4 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.0 GO:0097447 dendritic tree(GO:0097447)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.0 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.0 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.5 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.0 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.6 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 1.0 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation