Motif ID: HOXA2_HOXB1

Z-value: 0.560

Transcription factors associated with HOXA2_HOXB1:

Gene SymbolEntrez IDGene Name
HOXA2 ENSG00000105996.5 HOXA2
HOXB1 ENSG00000120094.6 HOXB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA2hg19_v2_chr7_-_27142290_271424300.203.4e-01Click!
HOXB1hg19_v2_chr17_-_46608272_466083850.029.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA2_HOXB1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151561506 2.472 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561085 2.376 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_205391178 1.351 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr2_-_190044480 1.277 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_2162162 1.247 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr15_-_74501360 1.238 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr11_-_111782484 0.905 ENST00000533971.1
CRYAB
crystallin, alpha B
chr4_-_90757364 0.727 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr10_-_100995540 0.686 ENST00000370546.1
ENST00000404542.1
HPSE2

heparanase 2

chr11_-_111782696 0.674 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr17_-_46623441 0.663 ENST00000330070.4
HOXB2
homeobox B2
chr4_-_90756769 0.659 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr3_-_51813009 0.619 ENST00000398780.3
IQCF6
IQ motif containing F6
chr17_+_37824700 0.608 ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chr19_-_51512804 0.555 ENST00000594211.1
ENST00000376832.4
KLK9

kallikrein-related peptidase 9

chr17_+_39975544 0.539 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_39975455 0.516 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_37824217 0.502 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr15_-_64673630 0.499 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chr12_+_21168630 0.477 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr17_+_37824411 0.474 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr10_-_79397202 0.449 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1


potassium large conductance calcium-activated channel, subfamily M, alpha member 1


chr10_-_79397316 0.443 ENST00000372421.5
ENST00000457953.1
KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

chr1_-_182641367 0.435 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr12_+_7023491 0.422 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chr9_+_132099158 0.411 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chrX_-_30993201 0.395 ENST00000288422.2
ENST00000378932.2
TAB3

TGF-beta activated kinase 1/MAP3K7 binding protein 3

chr5_+_167181917 0.377 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr17_+_7758374 0.362 ENST00000301599.6
ENST00000574668.1
TMEM88

transmembrane protein 88

chr10_-_79397479 0.362 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_100995603 0.361 ENST00000370552.3
ENST00000370549.1
HPSE2

heparanase 2

chr11_-_126870655 0.354 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr1_-_43833628 0.339 ENST00000413844.2
ENST00000372458.3
ELOVL1

ELOVL fatty acid elongase 1

chr11_+_57365150 0.331 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr7_-_144107320 0.314 ENST00000483238.1
ENST00000467773.1
NOBOX

NOBOX oogenesis homeobox

chr10_-_98945515 0.305 ENST00000371070.4
SLIT1
slit homolog 1 (Drosophila)
chr9_-_127269661 0.304 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr7_-_143956815 0.301 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr7_+_86273218 0.295 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr17_-_27418537 0.292 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chrX_+_99899180 0.282 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr15_-_95870310 0.279 ENST00000508732.2
CTD-2536I1.1
CTD-2536I1.1
chr12_+_101988627 0.257 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr1_-_182642017 0.252 ENST00000367557.4
ENST00000258302.4
RGS8

regulator of G-protein signaling 8

chr17_-_37353950 0.244 ENST00000394310.3
ENST00000394303.3
ENST00000344140.5
CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr7_-_86595190 0.235 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L


KIAA1324-like


chr8_-_143961236 0.233 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1


cytochrome P450, family 11, subfamily B, polypeptide 1


chr22_-_39151463 0.229 ENST00000405510.1
ENST00000433561.1
SUN2

Sad1 and UNC84 domain containing 2

chr1_+_178062855 0.227 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr12_+_57610562 0.224 ENST00000349394.5
NXPH4
neurexophilin 4
chr14_+_68189190 0.224 ENST00000539142.1
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr16_+_30080857 0.223 ENST00000565355.1
ALDOA
aldolase A, fructose-bisphosphate
chr7_-_27170352 0.219 ENST00000428284.2
ENST00000360046.5
HOXA4

homeobox A4

chr12_+_101988774 0.214 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1





myosin binding protein C, slow type





chr7_-_27135591 0.208 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr17_+_36584662 0.206 ENST00000431231.2
ENST00000437668.3
ARHGAP23

Rho GTPase activating protein 23

chr14_-_81893734 0.201 ENST00000555447.1
STON2
stonin 2
chr1_+_243419306 0.200 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr7_-_150864635 0.200 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr15_-_64673665 0.196 ENST00000300035.4
KIAA0101
KIAA0101
chr17_-_57229155 0.193 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr10_-_105615164 0.192 ENST00000355946.2
ENST00000369774.4
SH3PXD2A

SH3 and PX domains 2A

chr12_-_28124903 0.191 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr12_+_56414851 0.184 ENST00000547167.1
IKZF4
IKAROS family zinc finger 4 (Eos)
chr9_+_124329336 0.180 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr3_+_189507523 0.177 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr9_-_36276966 0.173 ENST00000543356.2
ENST00000396594.3
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr12_-_15038779 0.165 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr3_+_189507432 0.162 ENST00000354600.5
TP63
tumor protein p63
chr19_+_35849723 0.161 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr5_-_179045199 0.160 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr16_+_25703274 0.158 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr18_+_56887381 0.155 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
GRP


gastrin-releasing peptide


chr17_+_43239191 0.155 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr8_-_67874805 0.150 ENST00000563496.1
TCF24
transcription factor 24
chr5_+_145826867 0.135 ENST00000296702.5
ENST00000394421.2
TCERG1

transcription elongation regulator 1

chr2_-_197226875 0.133 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr5_+_162864575 0.133 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1






cyclin G1






chr17_+_79495397 0.129 ENST00000417245.2
ENST00000334850.7
FSCN2

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

chr20_+_42574317 0.128 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr2_+_68961934 0.125 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr1_+_68150744 0.123 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr3_+_150264555 0.120 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr8_+_143530791 0.120 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr7_+_20370746 0.118 ENST00000222573.4
ITGB8
integrin, beta 8
chr12_-_28125638 0.116 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr3_+_150264458 0.115 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr5_-_125930929 0.114 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr8_+_23386557 0.110 ENST00000523930.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr2_+_242089833 0.107 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7



protein phosphatase 1, regulatory subunit 7



chr2_+_68961905 0.106 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr9_-_73029540 0.098 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr7_-_27142290 0.087 ENST00000222718.5
HOXA2
homeobox A2
chr12_+_10658489 0.083 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr6_+_33387830 0.081 ENST00000293748.5
SYNGAP1
synaptic Ras GTPase activating protein 1
chr1_-_109584768 0.081 ENST00000357672.3
WDR47
WD repeat domain 47
chr6_+_33388013 0.078 ENST00000449372.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chr14_+_22985251 0.075 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr9_-_101471479 0.068 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr7_-_14029283 0.067 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr19_-_45735138 0.066 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chr3_+_148545586 0.065 ENST00000282957.4
ENST00000468341.1
CPB1

carboxypeptidase B1 (tissue)

chr19_+_13051206 0.064 ENST00000586760.1
CALR
calreticulin
chr12_-_86650077 0.063 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr1_-_109584716 0.062 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WDR47


WD repeat domain 47


chr7_+_26591441 0.062 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2


AC004947.2


chr10_+_24755416 0.061 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chrX_+_41583408 0.061 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr1_-_109584608 0.060 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47



WD repeat domain 47



chr15_-_74501310 0.060 ENST00000423167.2
ENST00000432245.2
STRA6

stimulated by retinoic acid 6

chrX_-_65253506 0.059 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr20_+_30467600 0.058 ENST00000375934.4
ENST00000375922.4
TTLL9

tubulin tyrosine ligase-like family, member 9

chr7_-_14029515 0.057 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chr12_+_57482877 0.056 ENST00000342556.6
ENST00000357680.4
NAB2

NGFI-A binding protein 2 (EGR1 binding protein 2)

chr6_-_112575912 0.055 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr17_-_1588101 0.053 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
PRPF8


pre-mRNA processing factor 8


chr8_+_23386305 0.053 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr4_-_102267953 0.053 ENST00000523694.2
ENST00000507176.1
PPP3CA

protein phosphatase 3, catalytic subunit, alpha isozyme

chr7_+_39017504 0.047 ENST00000403058.1
POU6F2
POU class 6 homeobox 2
chr8_-_143999259 0.047 ENST00000323110.2
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr15_+_48009541 0.044 ENST00000536845.2
ENST00000558816.1
SEMA6D

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr10_+_102505468 0.044 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2



paired box 2



chr20_+_34742650 0.043 ENST00000373945.1
ENST00000338074.2
EPB41L1

erythrocyte membrane protein band 4.1-like 1

chr10_+_18689637 0.043 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_+_113431059 0.042 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr6_+_50061315 0.040 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr20_+_52105495 0.035 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr20_+_34802295 0.031 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chrX_-_110655391 0.031 ENST00000356915.2
ENST00000356220.3
DCX

doublecortin

chr1_-_108507631 0.031 ENST00000527011.1
ENST00000370056.4
VAV3

vav 3 guanine nucleotide exchange factor

chr7_-_100881109 0.030 ENST00000308344.5
CLDN15
claudin 15
chr11_+_68228186 0.029 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3












protein phosphatase 6, regulatory subunit 3












chr16_-_49890016 0.026 ENST00000563137.2
ZNF423
zinc finger protein 423
chr19_+_52074502 0.021 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175


zinc finger protein 175


chrX_+_48455866 0.017 ENST00000376729.5
ENST00000218056.5
WDR13

WD repeat domain 13

chr2_-_145277882 0.013 ENST00000465070.1
ENST00000444559.1
ZEB2

zinc finger E-box binding homeobox 2

chr9_+_113431029 0.012 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK


muscle, skeletal, receptor tyrosine kinase


chr17_+_48609903 0.010 ENST00000268933.3
EPN3
epsin 3
chr3_+_191046810 0.009 ENST00000392455.3
ENST00000392456.3
CCDC50

coiled-coil domain containing 50

chr9_-_73477826 0.009 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3





transient receptor potential cation channel, subfamily M, member 3





chr13_-_36050819 0.009 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr12_-_58135903 0.008 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr20_-_22565101 0.005 ENST00000419308.2
FOXA2
forkhead box A2
chr1_+_67390578 0.005 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
MIER1






mesoderm induction early response 1, transcriptional regulator






chrY_+_26997726 0.004 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chr17_+_43239231 0.003 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2


hexamethylene bis-acetamide inducible 2


chr10_-_98945677 0.001 ENST00000266058.4
ENST00000371041.3
SLIT1

slit homolog 1 (Drosophila)

chr2_-_49381572 0.000 ENST00000454032.1
ENST00000304421.4
FSHR

follicle stimulating hormone receptor

chr6_+_32006159 0.000 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2


cytochrome P450, family 21, subfamily A, polypeptide 2



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.6 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.4 1.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 4.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.4 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 1.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.7 GO:0021569 rhombomere 3 development(GO:0021569)
0.2 1.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.1 0.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.2 GO:0019230 proprioception(GO:0019230)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.0 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 4.8 GO:0005938 cell cortex(GO:0005938)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.3 4.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.0 GO:0030305 heparanase activity(GO:0030305)
0.2 1.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.3 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions