Motif ID: HMX2

Z-value: 0.438


Transcription factors associated with HMX2:

Gene SymbolEntrez IDGene Name
HMX2 ENSG00000188816.3 HMX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HMX2hg19_v2_chr10_+_124907638_1249076600.377.6e-02Click!


Activity profile for motif HMX2.

activity profile for motif HMX2


Sorted Z-values histogram for motif HMX2

Sorted Z-values for motif HMX2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_111174054 0.623 ENST00000369770.3
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr10_-_7513904 0.483 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr1_+_209878182 0.414 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr5_-_146781153 0.413 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr18_+_42260861 0.405 ENST00000282030.5
SETBP1
SET binding protein 1
chr6_-_27858570 0.396 ENST00000359303.2
HIST1H3J
histone cluster 1, H3j
chr13_+_24144509 0.370 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr9_+_27109392 0.368 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr2_-_160654745 0.350 ENST00000259053.4
ENST00000429078.2
CD302

CD302 molecule

chr19_+_58144529 0.344 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211





zinc finger protein 211





chr18_-_24765248 0.335 ENST00000580774.1
ENST00000284224.8
CHST9

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9

chr1_-_110933611 0.335 ENST00000472422.2
ENST00000437429.2
SLC16A4

solute carrier family 16, member 4

chr4_-_70518941 0.304 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr7_-_7680601 0.299 ENST00000396682.2
RPA3
replication protein A3, 14kDa
chr21_-_34185944 0.297 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr6_+_151561085 0.288 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr9_-_116102562 0.283 ENST00000374193.4
ENST00000465979.1
WDR31

WD repeat domain 31

chr10_+_32873190 0.276 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr2_+_211342432 0.273 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr8_-_93978309 0.272 ENST00000517858.1
ENST00000378861.5
TRIQK

triple QxxK/R motif containing

chr15_+_41056255 0.263 ENST00000561160.1
ENST00000559445.1
GCHFR

GTP cyclohydrolase I feedback regulator

chr11_+_122753391 0.263 ENST00000307257.6
ENST00000227349.2
C11orf63

chromosome 11 open reading frame 63

chr7_+_123241908 0.263 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15


ankyrin repeat and SOCS box containing 15


chr9_-_116102530 0.262 ENST00000374195.3
ENST00000341761.4
WDR31

WD repeat domain 31

chr10_-_61900762 0.258 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_121379739 0.254 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr15_+_41056218 0.254 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr19_+_15852203 0.247 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr1_+_33546714 0.246 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC



arginine decarboxylase



chr8_-_93978333 0.245 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK


triple QxxK/R motif containing


chr8_-_93978346 0.244 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr1_-_151804314 0.241 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr6_-_51952367 0.234 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr21_+_31768348 0.224 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr10_-_121296045 0.220 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr17_+_67498538 0.218 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_112408768 0.214 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr4_-_168155169 0.206 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr8_+_77318769 0.202 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chrX_+_105937068 0.197 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_-_110933663 0.195 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4


solute carrier family 16, member 4


chr17_-_29641084 0.193 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr11_+_7618413 0.190 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_25652501 0.182 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chrX_+_36053908 0.180 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr8_-_93978357 0.179 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK





triple QxxK/R motif containing





chr17_-_15469590 0.178 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr12_+_47473369 0.176 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr1_+_99127225 0.176 ENST00000370189.5
ENST00000529992.1
SNX7

sorting nexin 7

chr7_+_97361218 0.172 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr12_-_122985067 0.170 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr4_-_39034542 0.169 ENST00000344606.6
TMEM156
transmembrane protein 156
chr11_-_74442430 0.166 ENST00000376332.3
CHRDL2
chordin-like 2
chr3_+_75955817 0.165 ENST00000487694.3
ENST00000602589.1
ROBO2

roundabout, axon guidance receptor, homolog 2 (Drosophila)

chr19_+_9361606 0.163 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr6_+_25754927 0.160 ENST00000377905.4
ENST00000439485.2
SLC17A4

solute carrier family 17, member 4

chr6_-_151773232 0.157 ENST00000444024.1
ENST00000367303.4
RMND1

required for meiotic nuclear division 1 homolog (S. cerevisiae)

chr4_+_25915822 0.155 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr12_+_81471816 0.155 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr4_+_25915896 0.152 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr5_-_114961673 0.152 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr1_+_109102652 0.152 ENST00000370035.3
ENST00000405454.1
FAM102B

family with sequence similarity 102, member B

chr6_-_26199471 0.146 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr7_-_84569561 0.146 ENST00000439105.1
AC074183.4
AC074183.4
chr19_+_41281416 0.136 ENST00000597140.1
MIA
melanoma inhibitory activity
chr3_+_122785895 0.132 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr1_-_108231101 0.130 ENST00000544443.1
ENST00000415432.2
VAV3

vav 3 guanine nucleotide exchange factor

chr2_+_1417228 0.129 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO







thyroid peroxidase







chr10_-_115613828 0.128 ENST00000361384.2
DCLRE1A
DNA cross-link repair 1A
chr19_-_36001113 0.126 ENST00000434389.1
DMKN
dermokine
chr15_+_54305101 0.126 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C


unc-13 homolog C (C. elegans)


chr7_-_87856303 0.125 ENST00000394641.3
SRI
sorcin
chr7_-_87856280 0.124 ENST00000490437.1
ENST00000431660.1
SRI

sorcin

chr13_+_27998681 0.124 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr6_-_46293378 0.124 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr4_-_138453606 0.124 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr17_-_295730 0.123 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr17_-_73663168 0.120 ENST00000578201.1
ENST00000423245.2
RECQL5

RecQ protein-like 5

chr1_+_70820451 0.120 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3




HERV-H LTR-associating 3




chr1_-_205290865 0.119 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr2_-_201374781 0.119 ENST00000359878.3
ENST00000409157.1
KCTD18

potassium channel tetramerization domain containing 18

chr1_-_67266939 0.117 ENST00000304526.2
INSL5
insulin-like 5
chrX_+_79675965 0.116 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr7_-_77325545 0.116 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1




RSBN1L antisense RNA 1




chr14_+_65381079 0.115 ENST00000549987.1
ENST00000542227.1
ENST00000447296.2
ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
CHURC1-FNTB
FNTB

CHURC1






CHURC1-FNTB readthrough
farnesyltransferase, CAAX box, beta

churchill domain containing 1






chrX_+_71996972 0.110 ENST00000334036.5
DMRTC1B
DMRT-like family C1B
chr12_-_10151773 0.110 ENST00000298527.6
ENST00000348658.4
CLEC1B

C-type lectin domain family 1, member B

chr7_+_77325738 0.109 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr12_+_133614119 0.109 ENST00000327668.7
ZNF84
zinc finger protein 84
chr18_+_45778672 0.107 ENST00000600091.1
AC091150.1
HCG1818186; Uncharacterized protein
chr7_+_5920429 0.107 ENST00000242104.5
OCM
oncomodulin
chr5_+_169659950 0.106 ENST00000593851.1
C5orf58
chromosome 5 open reading frame 58
chr17_-_38821373 0.106 ENST00000394052.3
KRT222
keratin 222
chr1_-_109935819 0.103 ENST00000538502.1
SORT1
sortilin 1
chr17_-_29641104 0.103 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr1_-_202858227 0.103 ENST00000367262.3
RABIF
RAB interacting factor
chr11_-_26588634 0.101 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr4_-_48782259 0.101 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL



FRY-like



chr3_-_108836977 0.100 ENST00000232603.5
MORC1
MORC family CW-type zinc finger 1
chr6_-_106773491 0.097 ENST00000360666.4
ATG5
autophagy related 5
chr12_-_72057571 0.097 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr5_-_58295712 0.095 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_100212132 0.095 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_+_148663729 0.095 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr3_-_46249878 0.091 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chrX_-_153979315 0.090 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3


GRB2-associated binding protein 3


chr9_-_111882195 0.089 ENST00000374586.3
TMEM245
transmembrane protein 245
chrX_+_36254051 0.086 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr2_+_158114051 0.086 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr5_+_3596168 0.083 ENST00000302006.3
IRX1
iroquois homeobox 1
chr17_-_73663245 0.083 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5



RecQ protein-like 5



chr15_+_67835517 0.082 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr11_-_101000445 0.082 ENST00000534013.1
PGR
progesterone receptor
chr6_+_26124373 0.081 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr6_+_64345698 0.080 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3




PHD finger protein 3




chr3_+_173116225 0.080 ENST00000457714.1
NLGN1
neuroligin 1
chr14_-_20801427 0.079 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1


cyclin B1 interacting protein 1, E3 ubiquitin protein ligase


chr19_-_52674896 0.078 ENST00000322146.8
ENST00000597065.1
ZNF836

zinc finger protein 836

chr2_+_108994633 0.078 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_-_115259337 0.077 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr14_+_31091511 0.077 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1





sec1 family domain containing 1





chr15_-_40074996 0.076 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr12_-_49463753 0.075 ENST00000301068.6
RHEBL1
Ras homolog enriched in brain like 1
chr13_+_49551020 0.075 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr6_-_46138676 0.075 ENST00000371383.2
ENST00000230565.3
ENPP5

ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)

chr12_-_112279694 0.075 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1

MAPKAPK5 antisense RNA 1

chr12_+_10163231 0.074 ENST00000396502.1
ENST00000338896.5
CLEC12B

C-type lectin domain family 12, member B

chr11_-_327537 0.072 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr4_+_37962018 0.066 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr7_+_75024903 0.063 ENST00000323819.3
ENST00000430211.1
TRIM73

tripartite motif containing 73

chr19_-_52674696 0.063 ENST00000597252.1
ZNF836
zinc finger protein 836
chr5_-_43397184 0.063 ENST00000513525.1
CCL28
chemokine (C-C motif) ligand 28
chr3_+_145782358 0.063 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr1_+_144151520 0.062 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chr10_-_99205607 0.062 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1





exosome component 1





chr20_-_47804894 0.061 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1







staufen double-stranded RNA binding protein 1







chr3_+_111697843 0.061 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10


abhydrolase domain containing 10


chr5_+_119867159 0.061 ENST00000505123.1
PRR16
proline rich 16
chr21_+_17909594 0.059 ENST00000441820.1
ENST00000602280.1
LINC00478

long intergenic non-protein coding RNA 478

chr14_-_50864006 0.057 ENST00000216378.2
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr5_+_61602055 0.055 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr12_-_15374343 0.055 ENST00000256953.2
ENST00000546331.1
RERG

RAS-like, estrogen-regulated, growth inhibitor

chr10_-_95241951 0.051 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF


myoferlin


chr11_-_40315640 0.048 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr2_+_152214098 0.048 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_-_95941987 0.046 ENST00000537435.2
USP44
ubiquitin specific peptidase 44
chr4_-_26492076 0.045 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr20_-_29978286 0.045 ENST00000376315.2
DEFB119
defensin, beta 119
chr14_+_57857262 0.044 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30


N(alpha)-acetyltransferase 30, NatC catalytic subunit


chr2_+_109237717 0.043 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr20_+_33104199 0.042 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
DYNLRB1



dynein, light chain, roadblock-type 1



chr4_-_155511887 0.041 ENST00000302053.3
ENST00000403106.3
FGA

fibrinogen alpha chain

chr19_+_52772821 0.040 ENST00000439461.1
ZNF766
zinc finger protein 766
chr19_-_44384291 0.039 ENST00000324394.6
ZNF404
zinc finger protein 404
chr9_-_98784042 0.039 ENST00000412122.2
LINC00092
long intergenic non-protein coding RNA 92
chr22_+_39795746 0.039 ENST00000216160.6
ENST00000331454.3
TAB1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

chr11_-_128894053 0.039 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chrX_+_134478706 0.037 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449


zinc finger protein 449


chr13_-_46756351 0.036 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_26199499 0.035 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr3_+_156799587 0.035 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr3_-_187009798 0.034 ENST00000337774.5
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr2_+_24272543 0.034 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr1_+_64669294 0.033 ENST00000371077.5
UBE2U
ubiquitin-conjugating enzyme E2U (putative)
chr20_+_42136308 0.033 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1



l(3)mbt-like 1 (Drosophila)



chr4_+_76649797 0.033 ENST00000538159.1
ENST00000514213.2
USO1

USO1 vesicle transport factor

chr12_+_25205568 0.033 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr5_-_169725231 0.032 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_+_12693336 0.029 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr17_+_28268623 0.029 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5



EF-hand calcium binding domain 5



chr4_-_69817481 0.029 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr17_+_54230819 0.029 ENST00000318698.2
ENST00000566473.2
ANKFN1

ankyrin-repeat and fibronectin type III domain containing 1

chr3_+_16216137 0.026 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr6_-_116833500 0.025 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr12_+_128399917 0.024 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr6_-_2751146 0.023 ENST00000268446.5
ENST00000274643.7
MYLK4

myosin light chain kinase family, member 4

chr12_+_107712173 0.023 ENST00000280758.5
ENST00000420571.2
BTBD11

BTB (POZ) domain containing 11

chr17_+_8243154 0.023 ENST00000328248.2
ENST00000584943.1
ODF4

outer dense fiber of sperm tails 4

chr7_-_14880892 0.022 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB


diacylglycerol kinase, beta 90kDa


chr4_+_83956312 0.022 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4


COP9 signalosome subunit 4


chr20_+_56964253 0.022 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr10_-_95242044 0.022 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF


myoferlin


chr4_+_83956237 0.020 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr6_-_26124138 0.020 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr1_+_239882842 0.020 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr4_+_108745711 0.019 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr2_-_134326009 0.018 ENST00000409261.1
ENST00000409213.1
NCKAP5

NCK-associated protein 5

chr18_-_10748498 0.018 ENST00000579949.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr1_+_15943995 0.016 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr15_+_55700741 0.016 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr10_-_126849588 0.015 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr1_-_11865351 0.012 ENST00000413656.1
ENST00000376585.1
ENST00000423400.1
ENST00000431243.1
MTHFR



methylenetetrahydrofolate reductase (NAD(P)H)



chr5_-_142814241 0.011 ENST00000504572.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_+_25205446 0.011 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr11_-_104893863 0.011 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5







caspase 5, apoptosis-related cysteine peptidase







chr2_+_106468204 0.010 ENST00000425756.1
ENST00000393349.2
NCK2

NCK adaptor protein 2

chr18_+_76829441 0.010 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr9_+_131843377 0.010 ENST00000372546.4
ENST00000406974.3
ENST00000540102.1
DOLPP1


dolichyldiphosphatase 1


chr1_-_70820357 0.009 ENST00000370944.4
ENST00000262346.6
ANKRD13C

ankyrin repeat domain 13C

chr17_+_45973516 0.008 ENST00000376741.4
SP2
Sp2 transcription factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.0 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.3 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0043194 spectrin-associated cytoskeleton(GO:0014731) axon initial segment(GO:0043194)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones