Motif ID: HIF1A

Z-value: 0.799


Transcription factors associated with HIF1A:

Gene SymbolEntrez IDGene Name
HIF1A ENSG00000100644.12 HIF1A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62162258_62162269-0.443.3e-02Click!


Activity profile for motif HIF1A.

activity profile for motif HIF1A


Sorted Z-values histogram for motif HIF1A

Sorted Z-values for motif HIF1A



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_19988462 2.144 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr1_+_150254936 1.844 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr4_-_186317034 1.304 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr12_+_7023735 1.197 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2


enolase 2 (gamma, neuronal)


chr12_+_7023491 1.189 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chrX_+_69509927 1.111 ENST00000374403.3
KIF4A
kinesin family member 4A
chr8_+_75896731 1.084 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr5_+_10441970 1.000 ENST00000274134.4
ROPN1L
rhophilin associated tail protein 1-like
chr3_-_145878954 0.998 ENST00000282903.5
ENST00000360060.3
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr2_-_28113965 0.947 ENST00000302188.3
RBKS
ribokinase
chr2_+_173420697 0.931 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1


pyruvate dehydrogenase kinase, isozyme 1


chr7_+_48075108 0.794 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
C7orf57




chromosome 7 open reading frame 57




chr2_-_220083076 0.764 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_5720666 0.740 ENST00000381624.3
ENST00000381614.2
CATSPERD

catsper channel auxiliary subunit delta

chr10_+_120789223 0.733 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr2_-_28113217 0.712 ENST00000444339.2
RBKS
ribokinase
chr11_+_74204395 0.708 ENST00000526036.1
AP001372.2
AP001372.2
chr14_-_64970494 0.643 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr19_-_55691614 0.637 ENST00000592470.1
ENST00000354308.3
SYT5

synaptotagmin V

chr4_-_39529049 0.619 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH


UDP-glucose 6-dehydrogenase


chr1_+_214454492 0.608 ENST00000366957.5
ENST00000415093.2
SMYD2

SET and MYND domain containing 2

chr5_-_146889619 0.604 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr4_-_39529180 0.604 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UGDH


UDP-glucose 6-dehydrogenase


chr18_+_43913919 0.554 ENST00000587853.1
RNF165
ring finger protein 165
chr7_+_128095945 0.550 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr11_-_76155700 0.526 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr16_+_66878814 0.523 ENST00000394069.3
CA7
carbonic anhydrase VII
chr12_-_49318715 0.522 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr8_+_26240414 0.482 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr4_-_104119528 0.478 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE


centromere protein E, 312kDa


chr2_-_220083671 0.473 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr8_+_17354617 0.463 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr3_+_100211412 0.462 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A


transmembrane protein 45A


chr6_+_151561506 0.460 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr16_-_30022735 0.459 ENST00000564944.1
DOC2A
double C2-like domains, alpha
chr17_-_34890759 0.456 ENST00000431794.3
MYO19
myosin XIX
chr2_-_220083692 0.456 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr6_+_151561085 0.455 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr10_-_93392811 0.453 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr1_+_22333943 0.448 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr4_+_129732467 0.447 ENST00000413543.2
PHF17
jade family PHD finger 1
chrX_-_13956737 0.439 ENST00000454189.2
GPM6B
glycoprotein M6B
chr22_+_41777927 0.427 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr7_+_128095900 0.425 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr2_-_216946500 0.418 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr8_+_17354587 0.412 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr11_-_63933504 0.408 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr22_-_24181174 0.404 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3



derlin 3



chr15_-_60884706 0.403 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr1_+_100436065 0.380 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr19_-_49137790 0.379 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr1_-_231376836 0.378 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr11_-_76155618 0.377 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr19_+_41903709 0.375 ENST00000542943.1
ENST00000457836.2
BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

chr19_-_1568057 0.373 ENST00000402693.4
ENST00000388824.6
MEX3D

mex-3 RNA binding family member D

chr1_-_26233423 0.369 ENST00000357865.2
STMN1
stathmin 1
chr19_-_49137762 0.368 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr17_+_80416050 0.366 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF


nuclear prelamin A recognition factor


chr7_+_26331541 0.364 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10


sorting nexin 10


chr16_-_30022293 0.363 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A


double C2-like domains, alpha


chr6_-_83775489 0.362 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr11_+_7534999 0.362 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr17_-_42908155 0.361 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1


gap junction protein, gamma 1, 45kDa


chrX_+_77359671 0.360 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chr6_+_35265586 0.354 ENST00000542066.1
ENST00000316637.5
DEF6

differentially expressed in FDCP 6 homolog (mouse)

chr2_+_27665232 0.350 ENST00000543753.1
ENST00000288873.3
KRTCAP3

keratinocyte associated protein 3

chr5_+_126112794 0.344 ENST00000261366.5
ENST00000395354.1
LMNB1

lamin B1

chr13_-_24463530 0.333 ENST00000382172.3
MIPEP
mitochondrial intermediate peptidase
chr2_-_68384603 0.332 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92


WD repeat domain 92


chr12_-_121734489 0.331 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2


calcium/calmodulin-dependent protein kinase kinase 2, beta


chr15_-_59665062 0.327 ENST00000288235.4
MYO1E
myosin IE
chrX_-_34675391 0.323 ENST00000275954.3
TMEM47
transmembrane protein 47
chr5_-_131563501 0.323 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2




prolyl 4-hydroxylase, alpha polypeptide II




chrX_-_13956497 0.322 ENST00000398361.3
GPM6B
glycoprotein M6B
chr12_+_110906169 0.319 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr17_-_73127353 0.317 ENST00000580423.1
ENST00000578337.1
ENST00000582160.1
NT5C


5', 3'-nucleotidase, cytosolic


chr2_+_27665289 0.316 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr11_-_17498348 0.314 ENST00000389817.3
ENST00000302539.4
ABCC8

ATP-binding cassette, sub-family C (CFTR/MRP), member 8

chr1_-_159894319 0.307 ENST00000320307.4
TAGLN2
transgelin 2
chrX_+_77359726 0.304 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chr17_-_57184260 0.304 ENST00000376149.3
ENST00000393066.3
TRIM37

tripartite motif containing 37

chr1_-_113498616 0.297 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1


solute carrier family 16 (monocarboxylate transporter), member 1


chr14_+_64970662 0.296 ENST00000556965.1
ENST00000554015.1
ZBTB1

zinc finger and BTB domain containing 1

chr11_-_118901559 0.296 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4



solute carrier family 37 (glucose-6-phosphate transporter), member 4



chr20_+_30946106 0.278 ENST00000375687.4
ENST00000542461.1
ASXL1

additional sex combs like 1 (Drosophila)

chr15_+_41056218 0.274 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr19_-_39440495 0.269 ENST00000448145.2
ENST00000599996.1
SARS2
CTC-360G5.8
seryl-tRNA synthetase 2, mitochondrial
Serine--tRNA ligase, mitochondrial
chr3_+_49044798 0.268 ENST00000438660.1
ENST00000608424.1
ENST00000415265.2
WDR6


WD repeat domain 6


chr4_+_37245799 0.265 ENST00000309447.5
KIAA1239
KIAA1239
chr1_-_113498943 0.264 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr8_-_95908902 0.262 ENST00000520509.1
CCNE2
cyclin E2
chr3_+_113666748 0.262 ENST00000330212.3
ENST00000498275.1
ZDHHC23

zinc finger, DHHC-type containing 23

chr14_-_24685246 0.260 ENST00000396833.2
ENST00000288087.7
MDP1

magnesium-dependent phosphatase 1

chrX_+_24483338 0.259 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr6_-_153304148 0.258 ENST00000229758.3
FBXO5
F-box protein 5
chr17_-_73127826 0.258 ENST00000582170.1
ENST00000245552.2
NT5C

5', 3'-nucleotidase, cytosolic

chr15_+_41056255 0.256 ENST00000561160.1
ENST00000559445.1
GCHFR

GTP cyclohydrolase I feedback regulator

chr3_-_81811312 0.254 ENST00000429644.2
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr11_+_6625046 0.249 ENST00000396751.2
ILK
integrin-linked kinase
chr11_+_9595180 0.247 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr11_-_18343669 0.247 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5


Hermansky-Pudlak syndrome 5


chr2_-_97652324 0.246 ENST00000490605.2
FAM178B
family with sequence similarity 178, member B
chr11_+_6624955 0.244 ENST00000299421.4
ENST00000537806.1
ILK

integrin-linked kinase

chr10_+_49514698 0.244 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8


mitogen-activated protein kinase 8


chr7_+_65540853 0.241 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL



argininosuccinate lyase



chr6_+_87865262 0.240 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr11_+_6624970 0.234 ENST00000420936.2
ENST00000528995.1
ILK

integrin-linked kinase

chr19_+_18530146 0.233 ENST00000348495.6
ENST00000270061.7
SSBP4

single stranded DNA binding protein 4

chr2_-_97652290 0.232 ENST00000327896.3
FAM178B
family with sequence similarity 178, member B
chrX_+_105969893 0.230 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr2_+_204192942 0.230 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr20_+_33464238 0.230 ENST00000360596.2
ACSS2
acyl-CoA synthetase short-chain family member 2
chr7_+_43152191 0.226 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr7_+_65540780 0.223 ENST00000304874.9
ASL
argininosuccinate lyase
chr13_+_27998681 0.223 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr12_+_28343365 0.223 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr19_-_5719860 0.222 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr8_-_103425047 0.220 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr20_+_33464407 0.219 ENST00000253382.5
ACSS2
acyl-CoA synthetase short-chain family member 2
chr3_+_63898275 0.214 ENST00000538065.1
ATXN7
ataxin 7
chr1_-_26232951 0.212 ENST00000426559.2
ENST00000455785.2
STMN1

stathmin 1

chr2_+_10183651 0.212 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr12_-_123849374 0.209 ENST00000602398.1
ENST00000602750.1
SBNO1

strawberry notch homolog 1 (Drosophila)

chr11_+_73498898 0.205 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48





mitochondrial ribosomal protein L48





chr12_+_58013693 0.203 ENST00000320442.4
ENST00000379218.2
SLC26A10

solute carrier family 26, member 10

chr13_+_103451399 0.202 ENST00000257336.1
ENST00000448849.2
BIVM

basic, immunoglobulin-like variable motif containing

chr2_+_32288657 0.201 ENST00000345662.1
SPAST
spastin
chr18_+_56530794 0.199 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532


zinc finger protein 532


chr6_-_159240415 0.196 ENST00000367075.3
EZR
ezrin
chr15_+_38544476 0.195 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr12_+_28343353 0.194 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr16_-_54963026 0.194 ENST00000560208.1
ENST00000557792.1
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr16_+_66914264 0.186 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr2_+_204193129 0.184 ENST00000417864.1
ABI2
abl-interactor 2
chr9_-_139922726 0.183 ENST00000265662.5
ENST00000371605.3
ABCA2

ATP-binding cassette, sub-family A (ABC1), member 2

chr15_+_89182178 0.183 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_+_32288725 0.182 ENST00000315285.3
SPAST
spastin
chr4_-_17783135 0.181 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr1_+_28052518 0.179 ENST00000530324.1
ENST00000234549.7
ENST00000373949.1
ENST00000010299.6
FAM76A



family with sequence similarity 76, member A



chr19_+_1407517 0.176 ENST00000336761.6
ENST00000233078.4
DAZAP1

DAZ associated protein 1

chr7_+_96747030 0.176 ENST00000360382.4
ACN9
ACN9 homolog (S. cerevisiae)
chr1_-_51425772 0.175 ENST00000371778.4
FAF1
Fas (TNFRSF6) associated factor 1
chr1_-_109506036 0.173 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
CLCC1



AKNAD1
chloride channel CLIC-like 1



AKNA domain containing 1
chr7_+_116593433 0.173 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr22_+_19701985 0.173 ENST00000455784.2
ENST00000406395.1
SEPT5

septin 5

chr2_+_88991162 0.171 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr14_-_53162361 0.170 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr22_+_40390930 0.170 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr6_-_153304697 0.170 ENST00000367241.3
FBXO5
F-box protein 5
chr1_-_43833628 0.168 ENST00000413844.2
ENST00000372458.3
ELOVL1

ELOVL fatty acid elongase 1

chr2_+_204193149 0.168 ENST00000422511.2
ABI2
abl-interactor 2
chr17_+_7608511 0.163 ENST00000226091.2
EFNB3
ephrin-B3
chr15_+_89181974 0.162 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_-_35969409 0.162 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG







synergin, gamma







chr17_+_80416482 0.155 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF





nuclear prelamin A recognition factor





chr17_-_8534031 0.155 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10


myosin, heavy chain 10, non-muscle


chr3_-_71632894 0.149 ENST00000493089.1
FOXP1
forkhead box P1
chr12_+_54332535 0.149 ENST00000243056.3
HOXC13
homeobox C13
chr19_-_5720123 0.146 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr17_-_8534067 0.146 ENST00000360416.3
ENST00000269243.4
MYH10

myosin, heavy chain 10, non-muscle

chr4_-_54930790 0.145 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr19_-_1237990 0.145 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
C19orf26


chromosome 19 open reading frame 26


chr9_-_94186131 0.144 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr11_-_62414070 0.144 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB




glucosidase, alpha; neutral AB




chr20_-_44540686 0.141 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
PLTP




phospholipid transfer protein




chr12_-_2113583 0.141 ENST00000397173.4
ENST00000280665.6
DCP1B

decapping mRNA 1B

chr4_+_17578815 0.139 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr22_-_31742218 0.139 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1


POZ (BTB) and AT hook containing zinc finger 1


chr10_-_44070016 0.138 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
ZNF239


zinc finger protein 239


chr5_+_55033845 0.138 ENST00000353507.5
ENST00000514278.2
ENST00000505374.1
ENST00000506511.1
DDX4



DEAD (Asp-Glu-Ala-Asp) box polypeptide 4



chr21_+_45719921 0.137 ENST00000349048.4
PFKL
phosphofructokinase, liver
chr5_+_49962772 0.132 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8




poly (ADP-ribose) polymerase family, member 8




chr3_+_25831567 0.131 ENST00000280701.3
ENST00000420173.2
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chr12_-_64616019 0.128 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66


chromosome 12 open reading frame 66


chr13_+_103451548 0.128 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr9_-_139922631 0.128 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_-_2206801 0.128 ENST00000544865.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr8_-_75233563 0.127 ENST00000342232.4
JPH1
junctophilin 1
chr11_-_76381781 0.126 ENST00000260061.5
ENST00000404995.1
LRRC32

leucine rich repeat containing 32

chr1_-_92351769 0.126 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr8_+_97274119 0.120 ENST00000455950.2
PTDSS1
phosphatidylserine synthase 1
chr14_+_96968802 0.119 ENST00000556619.1
ENST00000392990.2
PAPOLA

poly(A) polymerase alpha

chr17_+_57642886 0.117 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40




DEAH (Asp-Glu-Ala-His) box polypeptide 40




chr12_+_6977258 0.115 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
TPI1


triosephosphate isomerase 1


chr9_+_117373486 0.113 ENST00000288502.4
ENST00000374049.4
C9orf91

chromosome 9 open reading frame 91

chr7_-_22396533 0.112 ENST00000344041.6
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr16_+_2098003 0.110 ENST00000439673.2
ENST00000350773.4
TSC2

tuberous sclerosis 2

chr17_+_6918354 0.110 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr8_-_103424916 0.110 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr15_+_43622843 0.109 ENST00000428046.3
ENST00000422466.2
ENST00000389651.4
ADAL


adenosine deaminase-like


chr14_-_77495007 0.109 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr11_-_65548265 0.106 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr11_-_57283159 0.104 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr4_+_76649797 0.102 ENST00000538159.1
ENST00000514213.2
USO1

USO1 vesicle transport factor

chr8_-_97273807 0.102 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1


MTERF domain containing 1


chr22_-_36424458 0.101 ENST00000438146.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr16_+_67198683 0.100 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
HSF4


heat shock transcription factor 4


chr17_+_76311791 0.100 ENST00000586321.1
AC061992.2
AC061992.2
chr6_-_43021612 0.099 ENST00000535468.1
CUL7
cullin 7
chr22_+_35653445 0.098 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4



HMG box domain containing 4




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 1.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.3 0.9 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.2 1.0 GO:0035425 autocrine signaling(GO:0035425)
0.2 1.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 0.6 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 1.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 0.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.2 0.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 1.7 GO:0015886 heme transport(GO:0015886)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.4 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.4 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.1 0.3 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 3.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.3 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.4 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.0 1.0 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 1.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.0 0.6 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.6 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.4 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.0 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 2.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0097513 myosin II filament(GO:0097513)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.3 2.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 1.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.7 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 0.9 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.2 0.6 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 0.5 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.4 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.4 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.6 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 2.3 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 1.2 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA