Motif ID: HIC1
Z-value: 0.789

Transcription factors associated with HIC1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HIC1 | ENSG00000177374.8 | HIC1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
HIC1 | hg19_v2_chr17_+_1959369_1959604, hg19_v2_chr17_+_1958388_1958404 | 0.04 | 8.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 289 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.4 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 1.1 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
0.1 | 0.9 | GO:0060992 | response to fungicide(GO:0060992) |
0.1 | 0.9 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.1 | 0.8 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
0.1 | 0.8 | GO:0060179 | male mating behavior(GO:0060179) |
0.1 | 0.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.1 | 0.7 | GO:0032455 | nerve growth factor processing(GO:0032455) |
0.1 | 0.7 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
0.0 | 0.7 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.1 | 0.6 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
0.1 | 0.6 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.0 | 0.6 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.6 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.0 | 0.6 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
0.0 | 0.6 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.0 | 0.6 | GO:0016266 | O-glycan processing(GO:0016266) |
0.2 | 0.5 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
0.2 | 0.5 | GO:0045062 | extrathymic T cell selection(GO:0045062) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 74 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.1 | GO:0034705 | potassium channel complex(GO:0034705) |
0.0 | 1.7 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.1 | 1.0 | GO:0070852 | cell body fiber(GO:0070852) |
0.1 | 1.0 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 1.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.9 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059) |
0.0 | 0.9 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.1 | 0.8 | GO:0098845 | postsynaptic endosome(GO:0098845) |
0.0 | 0.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 0.7 | GO:0005587 | collagen type IV trimer(GO:0005587) |
0.0 | 0.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.7 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.6 | GO:0005874 | microtubule(GO:0005874) |
0.0 | 0.6 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
0.1 | 0.5 | GO:0031251 | PAN complex(GO:0031251) |
0.0 | 0.5 | GO:0043219 | lateral loop(GO:0043219) |
0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 0.4 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
0.0 | 0.4 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 170 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.1 | 1.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 1.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.3 | 1.0 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
0.2 | 1.0 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
0.0 | 1.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 0.9 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.1 | 0.8 | GO:0043426 | MRF binding(GO:0043426) |
0.0 | 0.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.2 | 0.7 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
0.1 | 0.7 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
0.2 | 0.6 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
0.2 | 0.6 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
0.1 | 0.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.0 | 0.6 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.6 | GO:0003785 | actin monomer binding(GO:0003785) |
0.2 | 0.5 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
0.2 | 0.5 | GO:0098782 | mechanically-gated potassium channel activity(GO:0098782) |
0.1 | 0.5 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.5 | GO:0097016 | L27 domain binding(GO:0097016) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 21 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.7 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 1.1 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.8 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.8 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.6 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 0.6 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.6 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.0 | 0.5 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.5 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 0.5 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 0.3 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.3 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 0.3 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 0.2 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.1 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 0.1 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
0.0 | 0.1 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
0.0 | 0.1 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 40 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.5 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.1 | 1.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 1.4 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 1.3 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.2 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 1.0 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
0.0 | 1.0 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 1.0 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.7 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.6 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.6 | REACTOME_GAB1_SIGNALOSOME | Genes involved in GAB1 signalosome |
0.0 | 0.6 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.0 | 0.5 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.5 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.4 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.0 | 0.4 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 0.3 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
0.0 | 0.3 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.0 | 0.3 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 0.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |